Michal Tomasz Marzec

Michal Tomasz Marzec

Guest researcher


  1. Published

    Glucose-Regulated Protein 94 (GRP94): A Novel Regulator of Insulin-Like Growth Factor Production

    Argon, Y., Bresson, S. E., Marzec, Michal Tomasz & Grimberg, A., 2020, In: Cells. 9, 8, 12 p., 1844.

    Research output: Contribution to journalReviewResearchpeer-review

  2. Variation in GRP94 Activity Impacts Production of Igfs and Human Growth

    Argon, Y., Grimberg, A., Rosenfeld, R. G. & Marzec, Michal Tomasz, 2014, In: Endocrine Reviews. 35, 3

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Plasma gelsolin modulates cellular response to sphingosine 1-phosphate

    Bucki, R., Kulakowska, A., Byfield, F. J., Zendzian-Piotrowska, M., Baranowski, M., Marzec, Michal Tomasz, Winer, J. P., Ciccarelli, N. J., Gorski, J., Drozdowski, W., Bittman, R. & Janmey, P. A., 2010, In: American Journal of Physiology: Cell Physiology. 299, 6, p. C1516-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in beta-Cells

    Dahlby, T., Simon, C., Backe, M. B., Dahllof, M. S., Holson, E., Wagner, B. K., Boni-Schnetzler, M., Marzec, Michal Tomasz, Lundh, M. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences. 21, 21, 18 p., 8016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Utility of blood procalcitonin concentration in the management of cancer patients with infections

    Durnas, B., Watek, M., Wollny, T., Niemirowicz, K., Marzec, Michal Tomasz, Bucki, R. & Gozdz, S., 2016, In: OncoTargets and Therapy. 9, p. 469-475

    Research output: Contribution to journalReviewResearchpeer-review

  6. Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders.

    El-Salem, M., Raghunath, P. N., Marzec, Michal Tomasz, Wlodarski, P., Tsai, D., Hsi, E. & Wasik, M. A., 2007, In: Laboratory Investigation. 87, 1, p. 29-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Activation of mTORC1 signaling pathway in AIDS-related lymphomas.

    El-Salem, M., Raghunath, P. N., Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Robertson, E. & Wasik, M. A., 2009, In: American Journal of Pathology. 175, 2, p. 817-824 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling

    Ghiasi, S. M., Dahlby, T., Hede Andersen, C., Haataja, L., Petersen, S., Omar-Hmeadi, M., Yang, M., Pihl, Celina, Bresson, S. E., Khilji, Muhammad Saad, Klindt, K., Cheta, O., Perone, M. J., Tyrberg, B., Prats, C., Barg, S., Tengholm, A., Arvan, P., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, Apr 2019, In: Diabetes. 68, 4, p. 747-760 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    FK506-Binding Protein 2 Participates in Proinsulin Folding

    Hoefner, C., Bryde, T. H., Pihl, C., Tiedemann, S. N., Bresson, S. E., Hotiana, H. A., Khilji, M. S., Santos, T. D., Puglia, M., Pisano, P., Majewska, M., Durzynska, J., Klindt, K., Klusek, J., Perone, M. J., Bucki, R., Hägglund, P. M., Gourdon, P. E., Gotfryd, K., Urbaniak, E. & 5 others, Borowiak, M., Wierer, M., MacDonald, P. E., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, 2023, In: Biomolecules. 13, 1, 20 p., 152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Peroxisome Proliferator-Activated Receptor γ Promotes Lymphocyte Survival through Its Actions on Cellular Metabolic Activities.

    Jo, S., Yang, C., Miao, Q., Marzec, Michal Tomasz, Wasik, M. A., Lu, P. & Wang, Y. L., 2006, In: Journal of Immunology. 177, 6, p. 3737-3745 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4(+) T lymphocytes

    Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 15 Aug 2008, In: Journal of Immunology. 181, 4, p. 2506-2512

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

    Kasprzycka, M., Majewski, M., Wang, Z., Ptasznik, A., Wysocka, M., Zhang, Q., Marzec, Michal Tomasz, Gimotty, P., Crompton, M. R. & Wasik, M. A., 2006, In: American Journal of Pathology. 168, 5, p. 1631-1641 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    γc-Signaling Cytokines Induce a Regulatory T Cell Phenotype in Malignant CD4+ T Lymphocytes.

    Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-2512 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3

    Kasprzycka, M., Marzec, Michal Tomasz, Liu, X., Zhang, Q. & Wasik, M. A., 27 Jun 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 26, p. 9964-9969

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The inducible beta 5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient beta-cells and is overexpressed in type 2 diabetes pancreatic islets

    Khilji, Muhammad Saad, Bresson, S. E., Verstappen, D., Pihl, Celina, Andersen, Phillip Alexander Keller, Agergaard, Jette Bach, Dahlby, T., Holgersen Bryde, Tenna, Klindt, K., Nielsen, C. K., Walentinsson, A., Zivkovic, D., Bousquet, M., Tyrberg, B., Richardson, S. J., Morgan, N. G., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E892-E900

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β

    Khilji, Muhammad Saad, Verstappen, D., Dahlby, T., Prause, Michala Cecilie Burstein, Pihl, Celina, Bresson, S. E., Holgersen Bryde, Tenna, Andersen, Phillip Alexander Keller, Klindt, K., Zivkovic, D., Bousquet-Dubouch, M. P., Tyrberg, B., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, 2020, In: PLoS ONE. 15, 2, 21 p., e0222432.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells

    Khilji, Muhammad Saad, Faridi, P., Pinheiro-Machado, E., Hoefner, C., Dahlby, T., Aranha, R., Buus, Søren, Nielsen, M., Klusek, J., Mandrup-Poulsen, Thomas, Pandey, K., Purcell, A. W. & Marzec, Michal Tomasz, 2022, In: Biomedicines. 10, 4, 814.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    IDF2022-0254 Glutathione S-transferase P1 genetic variants influence the HbA1c level in diabetic patients

    Klusek, J., Głuszek, S., Orlewska, K., Marzec, Michal Tomasz, Wawszczak-kasza, M., Madej, Ł., Klusek, J., Witczak, B. & Orlewska, E., 2023, In: Diabetes Research and Clinical Practice. 197, Suppl. 1, 1 p., 110268.

    Research output: Contribution to journalConference articleResearchpeer-review

  19. Published

    NOS2 Polymorphism in Aspect of Left and Right-Sided Colorectal Cancer

    Klusek, J., Lewitowicz, P., Oblap, R., Orlewska, E., Witczak, B., Marzec, Michal Tomasz, Kozłowska-Geller, M., Nawacki, Ł., Wawszczak-Kasza, M., Kocańda, K., Jóźwik, A. & Głuszek, S., 2024, In: Journal of Clinical Medicine. 13, 4, 11 p., 937.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma.

    Lee, S., Marzec, Michal Tomasz, Liu, X., Wehrli, S., Kantekure, K., Ragunath, P. N., Nelson, D. S., Delikatny, E. J., Glickson, J. D. & Wasik, M. A., 2013, In: NMR in Biomedicine. 26, 1, p. 106-114 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Prediction and Early Detection of Response by NMR Spectroscopy and Imaging

    Lee, S., Arias-Mendoza, F., Poptani, H., Delikatny, E. J., Wasik, M., Marzec, Michal Tomasz, Schuster, S. J., Nasta, S. D., Svoboda, J., O'Connor, O. A., Smith, M. R. & Glickson, J. D., Jan 2012, In: PET Clinics. 7, 1, p. 119-26 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.

    Marzec, Michal Tomasz, Kasprzycka, M., Liu, X., Raghunath, P. N., Wlodarski, P. & Wasik, M. A., 2007, In: Oncogene. 26, 6, p. 813-821 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

    Marzec, Michal Tomasz, Kasprzycka, M., Liu, X., El-Salem, M., Halasa, K., Raghunath, P. N., Bucki, R., Wlodarski, P. & Wasik, M. A., 2007, In: Oncogene. 26, 38, p. 5606-5614 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells

    Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

    Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 129941679