Michael Lückmann

Michael Lückmann

Staff scientist


Publication year:
  1. 2019
  2. Published

    Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1

    Lückmann, Michael, Trauelsen, Mette, Bentsen, Marie Aare, Nissen, Tinne Amalie Damgaard, Martins, J., Fallah, Z., Nygaard, Mads Mørup, Papaleo, Elena, Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

    Jørgensen, Astrid Sissel, Larsen, O., Uetz-von Allmen, E., Lückmann, Michael, Legler, D. F., Frimurer, Thomas Michael, Veldkamp, C. T., Hjortø, Gertrud Malene & Rosenkilde, Mette, 2019, In : Frontiers in Immunology. 10, 14 p., 2156.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1

    Larsen, O., Lückmann, Michael, van der Velden, Wijnand Jacobus C, Oliva-Santiago, M., Brvar, M., Ulven, Trond, Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 2019, In : ACS Pharmacology & Translational Science. 2, 6, p. 429-441 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2018
  6. Published

    Ligand-selective small molecule modulators of the constitutively active vGPCR US28

    Amarandi, R., Lückmann, Michael, Melynis, M., Jakobsen, M. H., Fallah, Z., Spiess, Katja, Hjortø, Gertrud Malene, Pui, A., Frimurer, Thomas Michael & Rosenkilde, Mette, 2018, In : European Journal of Medicinal Chemistry. 155, p. 244-254

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1

    Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In : Scientific Reports. 8, 1, p. 1-18 10010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The HETE Is on FFAR1 and Pancreatic Islet Cells

    Trauelsen, Mette, Lückmann, Michael, Frimurer, Thomas Michael & Schwartz, Thue W., 2018, In : Cell Metabolism. 27, 2, p. 273-275 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Translating biased signaling in the ghrelin receptor system into differential in vivo functions

    Mende, F., Hundahl, C., Plouffe, B., Skov, Louise Julie, Sivertsen, B., Madsen, A. N., Lückmann, Michael, Diep, T. A., Offermanns, S., Frimurer, Thomas Michael, Bouvier, M. & Holst, Birgitte, 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10255-E10264 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2017
  11. Published

    Biased agonism and allosteric modulation of GPR183- a 7TM receptor also known as EBV-induced EBI2

    Daugvilaite, V., Madsen, C. M., Lückmann, Michael, Castello Echeverria, C., Sailer, A. W., Frimurer, Thomas Michael, Rosenkilde, Mette & Benned-Jensen, T., 2017, In : British Journal of Pharmacology. 174, 13, p. 2031–2042

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structure-based discovery of novel US28 small molecule ligands with different modes of action

    Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In : Chemical Biology & Drug Design. 89, 3, p. 289–296

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2016
  14. Published

    Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding

    Barington, L., Rummel, P. C., Lückmann, Michael, Pihl, H., Larsen, O., Daugvilaite, V., Johnsen, A. H., Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 19 May 2016, In : The Journal of Biological Chemistry. 291, 31, p. 16208-16220

    Research output: Contribution to journalJournal articleResearchpeer-review

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