Michael Lückmann

Michael Lückmann

Staff scientist


Publication year:
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1 - 10 out of 18Page size: 10
  1. 2022
  2. Published

    Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action

    Lückmann, Michael, Iliyaz, Aslihan Shenol, Nissen, T. A. D., Petersen, Jacob Emil, Kouvchinov, David, Schwartz, Thue W. & Frimurer, Thomas Michael, 2022, In: ACS Medicinal Chemistry Letters. 13, 12, p. 1839-1847

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2021
  4. Published

    Discovery of GPR183 Agonists Based on an Antagonist Scaffold

    Kjær, Viktoria Madeline Skovgaard, Ieremias, L., Daugvilaite, V., Lückmann, Michael, Frimurer, Thomas Michael, Ulven, Trond, Rosenkilde, Mette & Våbenø, J., 2021, In: ChemMedChem. 16, 17, p. 2623-2627

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor

    Smit, F. X., van der Velden, W. J. C., Kizilkaya, Hüsün Sheyma, Nørskov, A., Lückmann, Michael, Hansen, T. N., wbf943, wbf943, Qvotrup, K., Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: Structure. 29, 7, p. 679-693.e6 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Molecular mechanism of ligand binding pathways and activation of the succinate receptor

    Iliyaz, Aslihan Shenol, Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2021, In: European Biophysics Journal. 50, Suppl. 1, p. 160 1 p., P-234.

    Research output: Contribution to journal › Conference abstract in journal › Research

  7. 2020
  8. Published

    Structural basis for GPCR signaling by small polar versus large lipid metabolites-discovery of non-metabolite ligands

    Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2020, In: Current Opinion in Cell Biology. 63, p. 38-48

    Research output: Contribution to journal › Review › Research › peer-review

  9. 2019
  10. Published

    Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1

    Lückmann, Michael, Trauelsen, Mette, Bentsen, M. A., Nissen, T. A. D., Martins, J., Fallah, Z., Nygaard, M. M., Papaleo, E., Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

    Jørgensen, Astrid Sissel, Larsen, Olav, Uetz-von Allmen, E., Lückmann, Michael, Legler, D. F., Frimurer, Thomas Michael, Veldkamp, C. T., Hjortø, Gertrud Malene & Rosenkilde, Mette, 2019, In: Frontiers in Immunology. 10, 14 p., 2156.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1

    Larsen, Olav, Lückmann, Michael, van der Velden, W. J. C., Oliva-Santiago, M., Brvar, M., Ulven, Trond, Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 2019, In: ACS Pharmacology & Translational Science. 2, 6, p. 429-441 13 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  13. 2018
  14. Published

    Ligand-selective small molecule modulators of the constitutively active vGPCR US28

    Amarandi, R., Lückmann, Michael, Melynis, M., Jakobsen, M. H., Fallah, Z., Spiess, Katja, Hjortø, Gertrud Malene, Pui, A., Frimurer, Thomas Michael & Rosenkilde, Mette, 2018, In: European Journal of Medicinal Chemistry. 155, p. 244-254

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1

    Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 123541281