Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

    Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 20, p. 496-513

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity

    Pattison, D. I., Davies, Michael Jonathan, Levina, A., Dixon, N. E. & Lay, P. A., 2001, In : Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): implications for foam cell formation in atherosclerosis

    Ismael, F. O., Proudfoot, J. M., Brown, B. E., van Reyk, D. M., Croft, K. D., Davies, Michael Jonathan & Hawkins, C. L., May 2015, In : Archives of Biochemistry and Biophysics. 573, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells

    Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael Jonathan & Hawkins, Clare Louise, Dec 2013, In : Free Radical Biology & Medicine. 65, p. 1352-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein

    Knott, H. M., Baoutina, A., Davies, Michael Jonathan & Dean, R. T., 15 Apr 2002, In : Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Dalyb, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Olivere, L., 1 Mar 2011, In : Psychology and Health. 26, 3, p. 321-335 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Competitive kinetics as a tool to determine rate constants for reduction of ferrylmyoglobin by food components

    Jongberg, S., Lund, Marianne N., Pattison, D. I., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2016, In : Food Chemistry. 199, p. 36-41 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Competitive reduction of perferrylmyoglobin radicals by protein thiols and plant phenols

    Jongberg, S., Lund, Marianne N., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2014, In : Journal of Agricultural and Food Chemistry. 62, 46, p. 11279-11288 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Computational design of effective, bioinspired HOCl antioxidants: the role of intramolecular Cl+ and H+ shifts

    Karton, A., O'Reilly, R. J., Pattison, D. I., Davies, Michael Jonathan & Radom, L., 21 Nov 2012, In : Journal of the American Chemical Society. 134, 46, p. 19240-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions

    Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael Jonathan, 1 May 2006, In : Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action

    Tiwari, Manish Kumar, Hägglund, Per Mårten, Møller, I. M., Davies, Michael Jonathan & Bjerrum, Morten Jannik, 2019, In : Redox Biology. 26, 15 p., 101262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development

    Tweeddale, H. J., Hawkins, Clare Louise, Janmie, J. F., Truscott, R. J. W. & Davies, Michael Jonathan, Oct 2016, In : Free Radical Research. 50, 10, p. 1116-1130 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Degradation of extracellular matrix and its components by hypobromous acid

    Rees, M. D., McNiven, T. N. & Davies, Michael Jonathan, 15 Jan 2007, In : Biochemical Journal. 401, 2, p. 587-96 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid

    Kennett, E. C. & Davies, Michael Jonathan, 1 Sep 2008, In : Free Radical Biology & Medicine. 45, 5, p. 716-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, Jun 1998, In : Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism

    Kennett, E. C. & Davies, Michael Jonathan, 15 Apr 2007, In : Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis

    Moheimani, F., Morgan, P. E., van Reyk, D. M. & Davies, Michael Jonathan, Jun 2010, In : B B A - Reviews on Cancer. 1802, 6, p. 561-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cost effectiveness analysis

    Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M. E., Campbell, M. J., Heller, S., Khunti, K., Skinner, Timothy & Davies, Michael Jonathan, 26 Aug 2010, In : BMJ (Online). 341, 7770, c4093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Depressive symptoms in the first year from diagnosis of Type 2 diabetes: Results from the DESMOND trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Aug 2010, In : Diabetic Medicine. 27, 8, p. 965-967 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Detection and characterisation of radicals in biological materials using EPR methodology

    Hawkins, Clare Louise & Davies, Michael Jonathan, Feb 2014, In : B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods

    Davies, Michael Jonathan, 2016, In : Methods. 109, p. 21-30 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques

    Woods, A. A., Linton, S. M. & Davies, Michael Jonathan, 1 Mar 2003, In : Biochemical Journal. 370, Pt 2, p. 729-35 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Detection, identification, and quantification of oxidative protein modifications

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Journal of Biological Chemistry. 294, 51, p. 19683-19708

    Research output: Contribution to journalReviewResearchpeer-review

  24. Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses

    Gad, N. A., Mizdrak, J., Pattison, D. I., Davies, Michael Jonathan, Truscott, R. J. W. & Jamie, J. F., Feb 2014, In : Investigative Ophthalmology & Visual Science. 55, 2, p. 849-55 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

    Weber, D., Davies, Michael Jonathan & Grune, T., 1 Aug 2015, In : Redox Biology. 5, p. 367-380 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study

    Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In : Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Diabetes screening anxiety and beliefs

    Skinner, Timothy, Davies, Michael Jonathan, Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In : Diabetic Medicine. 22, 11, p. 1497-1502 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease

    Leung, C., Herath, C. B., Jia, Z., Andrikopoulos, S., Brown, B. E., Davies, Michael Jonathan, Rivera, L. R., Furness, J. B., Forbes, J. M. & Angus, P. W., 21 Sep 2016, In : World Journal of Gastroenterology. 22, 35, p. 8026-8040 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper

    Stadler, N., Lindner, R. A. & Davies, Michael Jonathan, 2004, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes

    Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael Jonathan, 1998, In : Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation

    Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael Jonathan, 27 Jul 2011, In : Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    EPR spin trapping of protein radicals

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers

    Pattison, D. I., Lay, P. A. & Davies, Michael Jonathan, 26 Jun 2000, In : Inorganic Chemistry. 39, 13, p. 2729-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Early events in copper-ion catalyzed oxidation of α-synuclein

    Tiwari, Manish Kumar, Leinisch, F., Sahin, C., Møller, I. M., Otzen, D. E., Davies, Michael Jonathan & Bjerrum, Morten Jannik, 2018, In : Free Radical Biology & Medicine. 121, p. 38-50 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin

    Krämer, Anna Carola & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin

    Krämer, Anna Carola, Torreggiani, A. & Davies, Michael Jonathan, 2017, In : Journal of Agricultural and Food Chemistry. 65, 47, p. 10258-10269 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins

    Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael Jonathan, 2011, In : Journal of Diabetes Research. 2011, p. 851280

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin

    Nielsen, L. R., Lund, Marianne N., Davies, Michael Jonathan, Nielsen, J. H. & Nielsen, S. B., 2018, In : International Dairy Journal. 79, p. 52-61 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte

    Murphy, P. G., Davies, Michael Jonathan, Columb, M. O. & Stratford, N., Apr 1996, In : British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals

    Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael Jonathan & Radom, L., 31 Aug 2006, In : Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care

    Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael Jonathan, 9 Jun 2012, In : BMJ (Online). 344, 7860, e2333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial

    Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In : BMJ. 336, 7642, p. 491-495 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models

    Chen, Z., Kondrashina, A., Greco, Ines, Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings

    Zacharias, T., Flouda, Konstantina, Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael Jonathan, 2020, In : Biochemical Pharmacology. 173, 14 p., 113631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]

    Zacharias, T., Flouda, Konstantina, Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael Jonathan, 20 May 2018, In : Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Feb 2009, In : Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

    Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael Jonathan, 1 Sep 2006, In : Biochemical Journal. 398, 2, p. 197-206 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael Jonathan, 4 Jul 2006, In : Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

    Fu, S., Davies, Michael Jonathan, Stocker, R. & Dean, R. T., 1 Aug 1998, In : Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins

    Zeng, J. & Davies, Michael Jonathan, Aug 2005, In : Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205