Michael Jonathan Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3, 2200 København N, 12.6, Building: 30
- 2021
- Published
Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues
Flouda, Konstantina, Gammelgaard, Bente, Davies, Michael Jonathan & Hawkins, Clare Louise, May 2021, In : Redox Biology. 41, 101873.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidation of protein disulfide bonds by singlet oxygen gives rise to glutathionylated proteins
Jiang, S., Carroll, L., Rasmussen, L. M. & Davies, Michael Jonathan, Jan 2021, In : Redox Biology. 38, 101822.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynein regulates Kv7.4 channel trafficking from the cell membrane
van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael Jonathan, Greenwood, Iain Andrew, Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In : Journal of General Physiology. 153, 3, 19 p., e202012760.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
Davies, Michael Jonathan, 2021, In : Pharmacology and Therapeutics. 218, 23 p., 107685.Research output: Contribution to journal › Review › Research › peer-review
- Published
Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage
Flouda, Konstantina, Mercer, J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2021, In : Free Radical Biology & Medicine. 166, p. 165-177Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Oxidant-induced glutathionylation at protein disulfide bonds
Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 20 Nov 2020, In : Free Radical Biology and Medicine. 160, p. 513-525 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization
Gamon, Luke Francis, Guo, Chaorui, He, Jianfei, Hägglund, Per Mårten, Hawkins, Clare Louise & Davies, Michael Jonathan, Sep 2020, In : Redox Biology. 36, 9 p., 101586.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
Guo, Chaorui, Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In : Redox Biology. 36, 14 p., 101666.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes
Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael Jonathan, Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In : Archives of Biochemistry and Biophysics. 689, 7 p., 108443.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway
Shu, N., Hägglund, Per Mårten, Cai, H., Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2020, In : Redox Biology. 29, UNSP 101400.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Azocompounds as generators of defined radical species: Contributions and challenges for free radical research
López-Alarcón, C., Fuentes-Lemus, E., Figueroa, J. D., Dorta, E., Schöneich, C. & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 160, p. 78-91Research output: Contribution to journal › Review › Research › peer-review
- Published
Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In : Scientific Reports. 13 p., 666.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols
Karimi, M., Crossett, B., Cordwell, S. J., Pattison, David & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 154, p. 62-74 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis
Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael Jonathan & Siebuhr, A. S., 2020, In : Scientific Reports. 10, 1, 10 p., 17300.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings
Zacharias, T., Flouda, Konstantina, Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael Jonathan, 2020, In : Biochemical Pharmacology. 173, 14 p., 113631.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion
Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In : RSC Advances. 10, 43, p. 25786-25800 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure
Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael Jonathan & Lund, Marianne N., 2020, In : Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone
Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael Jonathan, 2020, In : Redox Biology. 28, 9 p., 101335 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction kinetics of selenium -containing compounds with oxidants
Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 155, p. 58-68Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase
Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael Jonathan, 2020, In : Redox Biology. 28, 12 p., 101331.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages
Guo, Chaorui, Sileikaite, Inga, Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants. 9, 12, 14 p., 1255.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN−)
Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In : Redox Biology. 36, 13 p., 101641.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin
He, Jianfei, fjp320, fjp320, Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael Jonathan & Hägglund, Per Mårten, 2020, In : Redox Biology. 36, 11 p., 101631.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks
Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2020, In : Free Radical Biology and Medicine. 152, p. 61-73Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination
Möllers Blossom, Benedikt, Russo, D. A., Singh, Raushan Kumar, Van Oort, B., Keller, Malene Billeskov, Simonsen, Tor Ivan, Perzon, A., Gamon, Luke Francis, Davies, Michael Jonathan, Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In : ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease
Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants & Redox Signaling. 32, 13, p. 957-981Research output: Contribution to journal › Review › Research › peer-review
- Published
UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites
Leinisch, F., Mariotti, M., Andersen, Sofie Hagel, Lindemose, S., Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael Jonathan, 2020, In : Scientific Reports. 10, 1, 11 p., 3106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation
Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In : Free Radical Biology and Medicine. 153, p. 12-16 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]
Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]
Shu, N., Hägglund, Per Mårten & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S9-S9 8.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function: [Meeting Abstract]
Shu, N. & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S49-S49 168.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule
Davies, Michael Jonathan & Schiesser, C. H., 2019, In : New Journal of Chemistry. 43, 25, p. 9759-9765Research output: Contribution to journal › Review › Research › peer-review
- Published
3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism
Avila, F., Ravello, N., Zanocco, A. L., Gamon, Luke Francis, Davies, Michael Jonathan & Silva, E., 2019, In : Free Radical Biology and Medicine. 141, p. 103-114Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]
Gamon, Luke Francis & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Analysis of protein chlorination by mass spectrometry
Nybo, T., Davies, Michael Jonathan & Rogowska-Wrzesinska, A., 2019, In : Redox Biology. 26, 10 p., UNSP 101236.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan
Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 143, p. 375-386Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines
Carroll, L., Karton, A., Radom, L., Davies, Michael Jonathan & Pattison, D. I., 2019, In : Chemical Research in Toxicology. 32, 3, p. 513-525 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula
Chen, Z., Leinisch, F., Greco, Ines, Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 68-81Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase
Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 20, p. 496-513Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action
Tiwari, M. K., Hägglund, Per Mårten, Møller, I. M., Davies, Michael Jonathan & Bjerrum, Morten Jannik, 2019, In : Redox Biology. 26, 15 p., 101262.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection, identification, and quantification of oxidative protein modifications
Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Journal of Biological Chemistry. 294, 51, p. 19683-19708Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin
Krämer, Anna Carola & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models
Chen, Z., Kondrashina, A., Greco, Ines, Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}
Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael Jonathan & Siebuhr, A. S., 2019, In : Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells
Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 134, p. 526-536Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications
Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 24, UNSP 101226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]
Flouda, Konstantina, Davies, Michael Jonathan & Hawkins, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins: [Meeting Abstract]
Ignasiak-Kciuk, M., Shashikadze, B., Frackowiak, K., Gamon, Luke Francis, Davies, Michael Jonathan & Marciniak, B., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S30-S30 89.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function
Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 136, p. 118-134Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]
Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)
Tur, J. A., Jacob, C., Chaimbault, P., Tadayyon, M., Richling, E., Hermans, N., dos Santos, C. N., Diederich, M., Giblin, L., Elhabiri, M., Gaucher, C., Andreoletti, P., Fernandes, A., Davies, Michael Jonathan, Bartoszek, A. & Cherkaoui-Malki, M., 2019, In : Free Radical Research. 53, S1, p. 1163-1170Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching
David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Redox Biology. 24, 9 p., 101207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction of quinones with proteins: Kinetics of adduct formation, effects on enzymatic activity and protein structure, and potential reversibility of modifications
Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 137, p. 169-180Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode
Silva, E., Barrias, P., Fuentes-Lemus, E., Tirapegui, C., Aspee, A., Carroll, L., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 131, p. 133-143Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tempus fugit horizontal ellipsis
Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 1-1Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Whey proteins: targets of oxidation, or mediators of redox protection
Giblin, L., Yalcin, A. S., Bicim, G., Krämer, Anna Carola, Chen, Z., Callanan, M. J., Arranz, E. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, S1, p. 1136–1152 17 p.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function
Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, Oct 2018, In : Redox Biology. 19, p. 388-400Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals
Leinisch, F., Mariotti, M., Hägglund, Per Mårten & Davies, Michael Jonathan, Oct 2018, In : Free Radical Biology and Medicine. 126, p. 73-86Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aggregation of alpha- and beta- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation
Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Escobar, E., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 20 Aug 2018, In : Free Radical Biology and Medicine. 124, p. 176-188Research output: Contribution to journal › Journal article › Research › peer-review
- Published
alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent
Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael Jonathan & Lopez-Alarcon, C., 1 Aug 2018, In : Food Chemistry. 256, p. 119-128Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]
Zacharias, T., Flouda, Konstantina, Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael Jonathan, 20 May 2018, In : Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Apr 2018, In : Free Radical Biology and Medicine. 118, p. 126-136Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
Borges, E. L., Ignasiak, M. T., Velichenko, Y., Perin, G., Hutton, C. A., Davies, Michael Jonathan & Schiesser, C. H., 25 Mar 2018, In : Chemical Communications. 54, 24, p. 2990-2993Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael Jonathan, 1 Feb 2018, In : Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of extracellular matrix protein chlorination and oxidation by mass spectrometry: [Meeting Abstract]
Nybo, T., Davies, Michael Jonathan & Rogowska-Wrzesinska, A., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S56-S57 P-40.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Cardiac spheroid co-cultures as a novel in vitro model to study human heart microenvironment
Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Davies, Michael Jonathan, Figtree, G. & Gentile, C., 2018, In : Journal of Pharmacological and Toxicological Methods. 93, p. 167 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula: [Meeting Abstract]
Chen, Z., Leinisch, F., Greco, Ines, Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, Supplement 1, p. S47 1 p., P-8.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function: [Meeting Abstract]
Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2018, In : Free Radical Biology & Medicine. 120, S1, p. S24-S24 P-41 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Early events in copper-ion catalyzed oxidation of α-synuclein
Tiwari, M. K., Leinisch, F., Sahin, C., Møller, I. M., Otzen, D. E., Davies, Michael Jonathan & Bjerrum, Morten Jannik, 2018, In : Free Radical Biology & Medicine. 121, p. 38-50 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin
Nielsen, L. R., Lund, Marianne N., Davies, Michael Jonathan, Nielsen, J. H. & Nielsen, S. B., 2018, In : International Dairy Journal. 79, p. 52-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]
Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Identification and characterization of protein cross-links induced by oxidative reactions
Hägglund, Per Mårten, Mariotti, M. & Davies, Michael Jonathan, 2018, In : Expert Review of Proteomics. 15, 8, p. 665-681Research output: Contribution to journal › Review › Research › peer-review
- Published
Influence of O-2 on riboflavin-mediated photo-oxidation of lysozyme: [Meeting Abstract]
Silva, E., Tirapegui, C., Fuentes-Lemus, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Caroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S58-S59 P-46.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Kinetics and biological consequences of quinone-induced protein adduction: [Meeting Abstract]
Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, S1, p. S55-S55 P-34.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation
Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 2018, In : Journal of Proteome Research. 17, 6, p. 2017-2027Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanistic view of iodide in oxidative stress: [Meeting Abstract]
Kciuk, M. I., Davies, Michael Jonathan & Marciniak, B., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S122-S122 P-254.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis: [Meeting Absract]
Cai, H., Chuang, Christine & Davies, Michael Jonathan, 2018, In : International Journal of Experimental Pathology. 99, 6, p. A24-A24Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Nitration alters laminin polymerization: [Meeting Abstract]
Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, S1, p. S127-S127 P-271.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]
Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017)
Khramtsov, V. V. & Davies, Michael Jonathan, 2018, In : Free Radical Research. 52, 3, p. 305-306Research output: Contribution to journal › Editorial › Research
- 2017
- Published
Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 132-142 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins
Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 395-405 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications
Rykær, M., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 3 Nov 2017, In : Journal of Proteome Research. 16, 11, p. 3978-3988 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues
Leinisch, F., Mariotti, M., Rykaer, M., López-Alarcón, C., Hägglund, Per Mårten & Davies, Michael Jonathan, Nov 2017, In : Free Radical Biology & Medicine. 112, p. 240-252 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function
Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael Jonathan & López-Alarcón, C., Nov 2017, In : Free Radical Biology and Medicine. 112, p. 60-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiac spheroids as promising in vitro models to study the human heart microenvironment
Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Figtree, G. A., Davies, Michael Jonathan & Gentile, C., 1 Aug 2017, In : Scientific Reports. 7, 12 p., 7005.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1
Kovacevic, Z., Sahni, S., Lok, K. H., Davies, Michael Jonathan, Wink, D. A. & Richardson, D. R., May 2017, In : B B A - Reviews on Cancer. 1861, 5 Pt A, p. 995-999 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage
Skjoldager, N., Blanner Bang, M., Rykaer, M., Björnberg, O., Davies, Michael Jonathan, Svensson, B., Harris, P. & Hägglund, Per Mårten, Apr 2017, In : Scientific Reports. 7, 10 p., 46282.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma
Havelund, J. F., Wojdyla, K. I., Davies, Michael Jonathan, Jensen, O. N., Møller, I. M. & Rogowska-Wrzesinska, A., 6 Mar 2017, In : Journal of Proteomics. 156, p. 40-51 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification
Forman, H. J., Davies, Michael Jonathan, Krämer, Anna Carola, Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In : Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
1,4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress
Ng, H. H., Leo, C. H., O'Sullivan, K., Alexander, S., Davies, Michael Jonathan, Schiesser, C. H. & Parry, L. J., Mar 2017, In : Biochemical Pharmacology. 128, p. 34-45 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxides and protein oxidation
Davies, Michael Jonathan, 1 Jan 2017, Hydrogen Peroxide Metabolism in Health and Disease. CRC Press, p. 101-124Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, 2017, In : Redox Biology. 12, p. 872-882 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin
Krämer, Anna Carola, Torreggiani, A. & Davies, Michael Jonathan, 2017, In : Journal of Agricultural and Food Chemistry. 65, 47, p. 10258-10269 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function
Indo, H. P., Hawkins, Clare Louise, Nakanishi, I., Matsumoto, K., Matsui, H., Suenaga, S., Davies, Michael Jonathan, St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Vol. 240. p. 439-456 18 p. (Handbook of Experimental Pharmacology, Vol. 240).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The immunoproteasome is induced by cytokines and regulates apoptosis in human islets
Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael Jonathan, Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In : Journal of Endocrinology. 233, 3, p. 369-379 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space
Indo, H. P., Majima, H. J., Terada, M., Suenaga, S., Tomita, K., Yamada, S., Higashibata, A., Ishioka, N., Kanekura, T., Nonaka, I., Hawkins, Clare Louise, Davies, Michael Jonathan, Clair, D. K. S. & Mukai, C., 16 Dec 2016, In : Scientific Reports. 6, 10 p., 39015.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability
Karimi, M., Ignasiak, M. T., Chan, B., Croft, A. K., Radom, L., Schiesser, C. H., Pattison, D. I. & Davies, Michael Jonathan, 12 Dec 2016, In : Scientific Reports. 6, 12 p., 38572.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Special issue for the 7th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia 2015 Thailand)
Ungsurungsie, M., Surh, Y., Toyokuni, S. & Davies, Michael Jonathan, 2 Oct 2016, In : Free Radical Research. 50, 10, p. 1045-1046Research output: Contribution to journal › Editorial › Research
- Published
Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development
Tweeddale, H. J., Hawkins, Clare Louise, Janmie, J. F., Truscott, R. J. W. & Davies, Michael Jonathan, Oct 2016, In : Free Radical Research. 50, 10, p. 1116-1130 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease
Leung, C., Herath, C. B., Jia, Z., Andrikopoulos, S., Brown, B. E., Davies, Michael Jonathan, Rivera, L. R., Furness, J. B., Forbes, J. M. & Angus, P. W., 21 Sep 2016, In : World Journal of Gastroenterology. 22, 35, p. 8026-8040 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxynitrite-mediated oxidation of plasma fibronectin
Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael Jonathan, Aug 2016, In : Free Radical Biology & Medicine. 97, p. 602-615 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues
Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael Jonathan, 1 Jan 2016, In : Free Radical Biology & Medicine. 90, p. 195-205 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages
Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : Free Radical Biology & Medicine. 94, p. 88-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chasing Great Paths of Helmut “Oxidative Stress” Sies
Majima, H., Indo, H., Nakanishi, I., Suenaga, S., Matsumoto, K., Matsui, H., Minamiyami, Y., Ichikawa, H., Yen, H., Hawkins, C., Davies, Michael Jonathan, Ozawa, T. & St. Clair, D., 2016, In : Archives of Biochemistry and Biophysics. 595, p. 54-60 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Competitive kinetics as a tool to determine rate constants for reduction of ferrylmyoglobin by food components
Jongberg, S., Lund, Marianne N., Pattison, D. I., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2016, In : Food Chemistry. 199, p. 36-41 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods
Davies, Michael Jonathan, 2016, In : Methods. 109, p. 21-30 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells
Talib, J. & Davies, Michael Jonathan, 2016, In : Journal of Biological Inorganic Chemistry. 21, 3, p. 305-317 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Key role of cysteine residues and sulfenic acids in thermal- and H2O2-mediated modification of β-lactoglobulin
Krämer, Anna Carola, Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael Jonathan, 2016, In : Free Radical Biology & Medicine. 97, 8, p. 544–555 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Key role of cysteine residues in thermal- and H2O2-mediated modification of beta-lactoglobulin
Krämer, Anna Carola, Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael Jonathan, 2016, In : Free Radical Biology & Medicine. 96, Suppl. 1, p. S16 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals
Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2016, In : RSC Advances. 6, 63, p. 57948-57955 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein oxidation and peroxidation
Davies, Michael Jonathan, 2016, In : Biochemical Journal. 473, 7, p. 805-825 21 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Quinone-induced protein modifications: kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins
Li, Y., Jongberg, S., Andersen, Mogens Larsen, Davies, Michael Jonathan & Lund, Marianne N., 2016, In : Free Radical Biology & Medicine. 97, p. 148-157 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?
Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : P L o S One. 11, 12, 16 p., e0168844.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Temperature Activated Diffusion of Radicals through Ion Implanted Polymers
Wakelin, E. A., Davies, Michael Jonathan, Bilek, M. M. M. & McKenzie, D. R., 2 Dec 2015, In : A C S Applied Materials and Interfaces. 7, 47, p. 26340-26345 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance
Storkey, C., Pattison, D. I., Ignasiak, M. T., Schiesser, C. H. & Davies, Michael Jonathan, Dec 2015, In : Free Radical Biology & Medicine. 89, p. 1049-1056 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin
Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael Jonathan, Dec 2015, In : Free Radical Biology & Medicine. 89, p. 721-733 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions
Weber, D., Davies, Michael Jonathan & Grune, T., 1 Aug 2015, In : Redox Biology. 5, p. 367-380 14 p.Research output: Contribution to journal › Review › Research › peer-review
Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion
Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael Jonathan, Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In : Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, Jul 2015, In : Free Radical Biology & Medicine. 84, p. 279-288 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): implications for foam cell formation in atherosclerosis
Ismael, F. O., Proudfoot, J. M., Brown, B. E., van Reyk, D. M., Croft, K. D., Davies, Michael Jonathan & Hawkins, C. L., May 2015, In : Archives of Biochemistry and Biophysics. 573, p. 40-51 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice
Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael Jonathan, May 2015, In : Atherosclerosis. 240, 1, p. 234-241 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences
Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael Jonathan & Spickett, C. M., Apr 2015, In : Free Radical Research. 49, 4, p. 347-73 27 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase
Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael Jonathan, 27 Mar 2015, In : Free Radical Research. 49, 6, p. 743-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation
Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, Michael Jonathan, Beattie, J. H. & Galley, H. F., 2015, In : British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants
Carroll, L., Davies, Michael Jonathan & Pattison, D. I., 2015, In : Free Radical Research. 49, 6, p. 750-767 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sulfur and selenium in oxidation protection
Davies, Michael Jonathan, 2015, In : La chimica e l’industria, Chimica & Materiali. 2015, 6, p. 50-54Research output: Contribution to journal › Review › Research › peer-review
- 2014
Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants
Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael Jonathan, Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In : Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction
Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael Jonathan, Oct 2014, In : Free Radical Research. 48, 10, p. 1256-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation and modification of extracellular matrix and its role in disease
Chuang, Christine, Degendorfer, G. & Davies, Michael Jonathan, Sep 2014, In : Free Radical Research. 48, 9, p. 970-89 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach
Storkey, C., Davies, Michael Jonathan & Pattison, D. I., Aug 2014, In : Free Radical Biology & Medicine. 73, p. 60-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides
Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2014, In : Free Radical Biology & Medicine. 70, p. 96-105 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mechanisms of degradation of the natural high-potency sweetener (2R,4R)-monatin in mock beverage solutions
Storkey, C., Pattison, D. I., Gaspard, D. S., Hagestuen, E. D. & Davies, Michael Jonathan, 16 Apr 2014, In : Journal of Agricultural and Food Chemistry. 62, 15, p. 3476-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells
Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael Jonathan, 15 Apr 2014, In : Biochemical Journal. 459, 2, p. 313-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael Jonathan, Iozzo, R. V. & Whitelock, J. M., Apr 2014, In : Matrix Biology. 35, p. 112-22 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis
Dunn, L. L., Simpson, P. J. L., Prosser, H. C., Lecce, L., Yuen, G. S. C., Buckle, A., Sieveking, D. P., Vanags, L. Z., Lim, P. R., Chow, R. W. Y., Lam, Y. T., Clayton, Z., Bao, S., Davies, Michael Jonathan, Stadler, N., Celermajer, D. S., Stocker, R., Bursill, C. A., Cooke, J. P. & Ng, M. K. C., Feb 2014, In : Diabetes. 63, 2, p. 675-87 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Detection and characterisation of radicals in biological materials using EPR methodology
Hawkins, Clare Louise & Davies, Michael Jonathan, Feb 2014, In : B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.Research output: Contribution to journal › Review › Research › peer-review
Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses
Gad, N. A., Mizdrak, J., Pattison, D. I., Davies, Michael Jonathan, Truscott, R. J. W. & Jamie, J. F., Feb 2014, In : Investigative Ophthalmology & Visual Science. 55, 2, p. 849-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice
Brown, B. E., Kim, C. H. J., Torpy, F. R., Bursill, C. A., McRobb, L. S., Heather, A. K., Davies, Michael Jonathan & van Reyk, D. M., Feb 2014, In : Atherosclerosis. 232, 2, p. 403-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Increasing capacity to deliver diabetes self-management education: Results of the DESMOND lay educator non-randomized controlled equivalence trial
Carey, M. E., Mandalia, P. K., Daly, H., Gray, L. J., Hale, R., Martin Stacey, L., Taub, N., Skinner, Timothy, Stone, M., Heller, S., Khunti, K. & Davies, Michael Jonathan, 1 Jan 2014, In : Diabetic Medicine. 31, 11, p. 1431-1438 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction
Talib, J., Kwan, J., Suryo Rahmanto, A., Witting, P. K. & Davies, Michael Jonathan, 1 Jan 2014, In : Biochemical Journal. 457, 1, p. 89-97 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Competitive reduction of perferrylmyoglobin radicals by protein thiols and plant phenols
Jongberg, S., Lund, Marianne N., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2014, In : Journal of Agricultural and Food Chemistry. 62, 46, p. 11279-11288 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction
Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael Jonathan, Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In : American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731Research output: Contribution to journal › Journal article › Research › peer-review
Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal
Morgan, P. E., Sheahan, P. J. & Davies, Michael Jonathan, 2014, In : PloS one. 9, 1, 11 p., e86564.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells
Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael Jonathan & Hawkins, Clare Louise, Dec 2013, In : Free Radical Biology & Medicine. 65, p. 1352-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Superoxide radicals have a protective role during H2O2 stress
Thorpe, G. W., Reodica, M., Davies, Michael Jonathan, Heeren, G., Jarolim, S., Pillay, B., Breitenbach, M., Higgins, V. J. & Dawes, I. W., Sep 2013, In : Molecular Biology of the Cell. 24, 18, p. 2876-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biomarkers of oxidative stress study V: ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine
Kadiiska, M. B., Basu, S., Brot, N., Cooper, C., Saari Csallany, A., Davies, Michael Jonathan, George, M. M., Murray, D. M., Jackson Roberts, L., Shigenaga, M. K., Sohal, R. S., Stocker, R., Van Thiel, D. H., Wiswedel, I., Hatch, G. E. & Mason, R. P., Aug 2013, In : Free Radical Biology & Medicine. 61, p. 408-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes
Morgan, P. E., Sheahan, P. J., Pattison, D. I. & Davies, Michael Jonathan, Aug 2013, In : Free Radical Biology & Medicine. 61, p. 229-42 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
Graham, G. G., Davies, Michael Jonathan, Day, R. O., Mohamudally, A. & Scott, K. F., Jun 2013, In : Inflammopharmacology. 21, 3, p. 201-32 32 p.Research output: Contribution to journal › Journal article › Research › peer-review
Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals: role of oxidizable amino acid residues
Arenas, A., López-Alarcón, C., Kogan, M., Lissi, E., Davies, Michael Jonathan & Silva, E., 18 Jan 2013, In : Chemical Research in Toxicology. 26, 1, p. 67-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)
Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Jan 2013, In : Biochemical Journal. 449, 2, p. 531-42 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content
Thallas-Bonke, V., Coughlan, M. T., Tan, A. L., Harcourt, B. E., Morgan, P. E., Davies, Michael Jonathan, Bach, L. A., Cooper, M. E. & Forbes, J. M., Jan 2013, In : Nephrology. 18, 1, p. 47-56 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages
Brown, B. E., Nobecourt, E., Zeng, J., Jenkins, A. J., Rye, K. & Davies, Michael Jonathan, 2013, In : PLOS ONE. 8, 5, p. e65430Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins
Cook, N. L., Pattison, D. I. & Davies, Michael Jonathan, 1 Dec 2012, In : Free Radical Biology & Medicine. 53, 11, p. 2072-80 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Computational design of effective, bioinspired HOCl antioxidants: the role of intramolecular Cl+ and H+ shifts
Karton, A., O'Reilly, R. J., Pattison, D. I., Davies, Michael Jonathan & Radom, L., 21 Nov 2012, In : Journal of the American Chemical Society. 134, 46, p. 19240-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Preventing protein oxidation with sugars: scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives
Storkey, C., Pattison, D. I., White, J. M., Schiesser, C. H. & Davies, Michael Jonathan, 19 Nov 2012, In : Chemical Research in Toxicology. 25, 11, p. 2589-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies
Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael Jonathan, 1 Nov 2012, In : Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Selenium-containing amino acids as direct and indirect antioxidants
Rahmanto, A. S. & Davies, Michael Jonathan, Nov 2012, In : I U B M B Life. 64, 11, p. 863-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Photo-oxidation-induced inactivation of the selenium-containing protective enzymes thioredoxin reductase and glutathione peroxidase
Suryo Rahmanto, A., Pattison, D. I. & Davies, Michael Jonathan, 15 Sep 2012, In : Free Radical Biology & Medicine. 53, 6, p. 1308-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids
Pattison, D. I., Davies, Michael Jonathan & Hawkins, Clare Louise, Aug 2012, In : Free Radical Research. 46, 8, p. 975-95 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine
Talib, J., Pattison, D. I., Harmer, J. A., Celermajer, D. S. & Davies, Michael Jonathan, 1 Jul 2012, In : Free Radical Biology & Medicine. 53, 1, p. 20-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis
Moheimani, F., Kim, C. H. J., Rahmanto, A. S., van Reyk, D. M. & Davies, Michael Jonathan, Jul 2012, In : Atherosclerosis. 223, 1, p. 144-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care
Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael Jonathan, 9 Jun 2012, In : BMJ (Online). 344, 7860, e2333.Research output: Contribution to journal › Journal article › Research › peer-review
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Truscott, R. J. W., Mizdrak, J., Friedrich, M. G., Hooi, M. Y., Lyons, B., Jamie, J. F., Davies, Michael Jonathan, Wilmarth, P. A. & David, L. L., Jun 2012, In : Experimental Eye Research. 99, p. 48-54 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reduced metal ion concentrations in atherosclerotic plaques from subjects with type 2 diabetes mellitus
Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., Croft, K. D., Mori, T. A., Vacata, V., Daemen, M. J. A. P., Waltenberger, J. & Davies, Michael Jonathan, Jun 2012, In : Atherosclerosis. 222, 2, p. 512-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates
Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Mar 2012, In : Free Radical Biology & Medicine. 52, 6, p. 1075-85 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells
Cook, N. L., Viola, H. M., Sharov, V. S., Hool, L. C., Schöneich, C. & Davies, Michael Jonathan, 1 Mar 2012, In : Free Radical Biology & Medicine. 52, 5, p. 951-61 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline
Morgan, P. E., Pattison, D. I. & Davies, Michael Jonathan, 15 Jan 2012, In : Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage
Skaff, O., Pattison, D. I., Morgan, P. E., Bachana, R., Jain, V. K., Priyadarsini, K. I. & Davies, Michael Jonathan, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 305-16 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Free Radical Research origins
Davies, Michael Jonathan, Jan 2012, In : Free Radical Research. 46, 1, p. 1Research output: Contribution to journal › Journal article › Research
Photo-oxidation of proteins
Pattison, D. I., Rahmanto, A. S. & Davies, Michael Jonathan, Jan 2012, In : Photochemical & Photobiological Sciences. 11, 1, p. 38-53 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
Catalytic activity of selenomethionine in removing amino acid, peptide, and protein hydroperoxides
Suryo Rahmanto, A. & Davies, Michael Jonathan, 15 Dec 2011, In : Free Radical Biology & Medicine. 51, 12, p. 2288-99 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase
Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2011, In : Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mechanisms and consequences of oxidative damage to extracellular matrix
Kennett, E. C., Chuang, Christine, Degendorfer, G., Whitelock, J. M. & Davies, Michael Jonathan, Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1279-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis and antioxidant capacity of 5-selenopyranose derivatives
Storkey, C., Davies, Michael Jonathan, White, J. M. & Schiesser, C. H., 14 Sep 2011, In : Chemical communications (Cambridge, England). 47, 34, p. 9693-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study
Crasto, W., Jarvis, J., Khunti, K., Skinner, Timothy, Gray, L. J., Brela, J., Troughton, J., Daly, H., Lawrence, I. G., McNally, P. G., Carey, M. E. & Davies, Michael Jonathan, 1 Sep 2011, In : Diabetes Research and Clinical Practice. 93, 3, p. 328-336 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima
Mai, K., Smith, N. C., Feng, Z., Katrib, M., Slapeta, J., Slapetova, I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan, Zhang, X., Norton, R. S. & Belli, S. I., Sep 2011, In : International Journal for Parasitology (Online). 41, 11, p. 1157-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation
Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael Jonathan, 27 Jul 2011, In : Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between anxiety and measures of glycaemia in a population-based diabetes screening programme
Aujla, N., Davies, Michael Jonathan, Skinner, Timothy, Gray, L. J., Webb, D. R., Srinivasan, Balaji & Khunti, K., 1 Jul 2011, In : Diabetic Medicine. 28, 7, p. 785-788 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
One-electron reduction of N-chlorinated and N-brominated species is a source of radicals and bromine atom formation
Pattison, D. I., O'Reilly, R. J., Skaff, O., Radom, L., Anderson, R. F. & Davies, Michael Jonathan, 21 Mar 2011, In : Chemical Research in Toxicology. 24, 3, p. 371-82 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial
Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Dalyb, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Olivere, L., 1 Mar 2011, In : Psychology and Health. 26, 3, p. 321-335 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome
Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Jan 2011, In : Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention
Davies, Michael Jonathan, Jan 2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 8-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins
Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael Jonathan, 2011, In : Journal of Diabetes Research. 2011, p. 851280Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3
Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, Michael Jonathan & Winterbourn, C. C., 1 Dec 2010, In : Biochemical Journal. 432, 2, p. 313-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: A cross-sectional study
Gray, L. J., Tringham, J. R., Davies, Michael Jonathan, Webb, D. R., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Dec 2010, In : Vascular Health and Risk Management. 6, 1, p. 837-842 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts
Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael Jonathan, 30 Nov 2010, In : Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cost effectiveness analysis
Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M. E., Campbell, M. J., Heller, S., Khunti, K., Skinner, Timothy & Davies, Michael Jonathan, 26 Aug 2010, In : BMJ (Online). 341, 7770, c4093.Research output: Contribution to journal › Journal article › Research › peer-review
The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages
Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael Jonathan, 15 Aug 2010, In : Biochemical Journal. 430, 1, p. 161-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depressive symptoms in the first year from diagnosis of Type 2 diabetes: Results from the DESMOND trial
Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Aug 2010, In : Diabetic Medicine. 27, 8, p. 965-967 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: A comparison of two screening tools
Aujla, N., Skinner, Timothy, Khunti, K. & Davies, Michael Jonathan, 1 Aug 2010, In : Diabetic Medicine. 27, 8, p. 896-905 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains
Kennett, E. C., Rees, M. D., Malle, E., Hammer, A., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jul 2010, In : Free Radical Biology & Medicine. 49, 2, p. 282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis
Moheimani, F., Morgan, P. E., van Reyk, D. M. & Davies, Michael Jonathan, Jun 2010, In : B B A - Reviews on Cancer. 1802, 6, p. 561-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations
Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 15 Apr 2010, In : Biochemical Pharmacology. 79, 8, p. 1156-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cellular effects of peptide and protein hydroperoxides
Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Apr 2010, In : Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study
Khunti, K., Taub, N., Tringham, J., Jarvis, J., Farooqi, A., Skinner, Timothy & Davies, Michael Jonathan, 1 Apr 2010, In : Primary Care Diabetes. 4, 1, p. 25-32 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I
Nobécourt, E., Tabet, F., Lambert, G., Puranik, R., Bao, S., Yan, L., Davies, Michael Jonathan, Brown, B. E., Jenkins, A. J., Dusting, G. J., Bonnet, D. J., Curtiss, L. K., Barter, P. J. & Rye, K., Apr 2010, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 766-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between depression and health-related quality of life in people with type 2 diabetes: A systematic literature review
Ali, S., Stone, M., Skinner, Timothy, Robertson, N., Davies, Michael Jonathan & Khunti, K., 1 Feb 2010, In : Diabetes/Metabolism Research and Reviews. 26, 2, p. 75-89 15 p.Research output: Contribution to journal › Review › Research › peer-review
Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction
Szuchman-Sapir, A. J., Pattison, D. I., Davies, Michael Jonathan & Witting, P. K., 1 Jan 2010, In : Free Radical Biology & Medicine. 48, 1, p. 35-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan
Rees, M. D., Whitelock, J. M., Malle, E., Chuang, Christine, Iozzo, R. V., Nilasaroya, A. & Davies, Michael Jonathan, Jan 2010, In : Matrix Biology. 29, 1, p. 63-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy
Sourris, K. C., Harcourt, B. E., Penfold, S. A., Yap, F. Y. T., Morley, A. L., Morgan, P. E., Davies, Michael Jonathan, Baker, S. T., Jerums, G. & Forbes, J. M., 2010, In : Journal of Diabetes Research. 2010, p. 974681Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus
Aujla, N., Abrams, K. R., Davies, Michael Jonathan, Taub, N., Skinner, Timothy & Khunti, K., 9 Nov 2009, In : PLoS ONE. 4, 11, e7755.Research output: Contribution to journal › Journal article › Research › peer-review
Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation
Kennett, E. C. & Davies, Michael Jonathan, 15 Aug 2009, In : Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance
Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 15 Aug 2009, In : Biochemical Journal. 422, 1, p. 111-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides
Rees, M. D., Bottle, S. E., Fairfull-Smith, K. E., Malle, E., Whitelock, J. M. & Davies, Michael Jonathan, 1 Jul 2009, In : Biochemical Journal. 421, 1, p. 79-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products
Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In : Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2009, In : Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of protein modification by oxidants
Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypobromous acid and bromamine production by neutrophils and modulation by superoxide
Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael Jonathan, 1 Feb 2009, In : Biochemical Journal. 417, 3, p. 773-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients
Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Feb 2009, In : Free Radical Research. 43, 2, p. 117-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation
Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In : Biochemical Journal. 416, 3, p. 441-52 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes: Baseline data from the DESMOND randomized controlled trial
Khunti, K., Skinner, Timothy, Heller, S., Carey, M. E., Dallosso, H. M. & Davies, Michael Jonathan, 1 Dec 2008, In : Diabetic Medicine. 25, 12, p. 1454-1461 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins
Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In : Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals
Lam, M. A., Pattison, D. I., Bottle, S. E., Keddie, D. J. & Davies, Michael Jonathan, Nov 2008, In : Chemical Research in Toxicology. 21, 11, p. 2111-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin
Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael Jonathan & Witting, P. K., 15 Sep 2008, In : Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
'Educator talk' and patient change: Some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial
Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Sep 2008, In : Diabetic Medicine. 25, 9, p. 1117-1120 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid
Kennett, E. C. & Davies, Michael Jonathan, 1 Sep 2008, In : Free Radical Biology & Medicine. 45, 5, p. 716-25 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid
Lloyd, M. M., van Reyk, D. M., Davies, Michael Jonathan & Hawkins, Clare Louise, 1 Sep 2008, In : Biochemical Journal. 414, 2, p. 271-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines
Summers, F. A., Morgan, P. E., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2008, In : Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study
Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 5 Aug 2008, In : Biochemistry. 47, 31, p. 8237-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study
Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael Jonathan, 1 Jul 2008, In : Patient Education and Counseling. 72, 1, p. 88-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mammalian heme peroxidases: from molecular mechanisms to health implications
Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidative damage to extracellular matrix and its role in human pathologies
Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jun 2008, In : Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation
Stadler, N., Stanley, N., Heeneman, S., Vacata, V., Daemen, M. J. A. P., Bannon, P. G., Waltenberger, J. & Davies, Michael Jonathan, May 2008, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 1024-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage
Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael Jonathan, 15 Mar 2008, In : Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial
Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In : BMJ. 336, 7642, p. 491-495 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The DESMOND educational intervention
Davies, Michael Jonathan, Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In : Chronic Illness. 4, 1, p. 38-40 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links
Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2008, In : Biochemical Journal. 410, 3, p. 565-574 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants
Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, Dec 2007, In : Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis
Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In : Free Radical Research. 41, 12, p. 1301-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides
Dremina, E. S., Sharov, V. S., Davies, Michael Jonathan & Schöneich, C., Oct 2007, In : Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 28 Aug 2007, In : Biochemistry. 46, 34, p. 9853-64 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses
Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., Aug 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products
Gracanin, M. & Davies, Michael Jonathan, 15 May 2007, In : Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism
Kennett, E. C. & Davies, Michael Jonathan, 15 Apr 2007, In : Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro
Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, 6 Mar 2007, In : FEBS letters. 581, 5, p. 1067-70 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, Mar 2007, In : F E B S Journal. 274, 6, p. 1530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of extracellular matrix and its components by hypobromous acid
Rees, M. D., McNiven, T. N. & Davies, Michael Jonathan, 15 Jan 2007, In : Biochemical Journal. 401, 2, p. 587-96 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study
Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In : Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions
Zeng, J. & Davies, Michael Jonathan, Dec 2006, In : Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols
Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael Jonathan, 1 Sep 2006, In : Biochemical Journal. 398, 2, p. 197-206 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals
Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael Jonathan & Radom, L., 31 Aug 2006, In : Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage
Pattison, D. I. & Davies, Michael Jonathan, 4 Jul 2006, In : Biochemistry. 45, 26, p. 8152-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions
Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael Jonathan, 1 May 2006, In : Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides
Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael Jonathan, 1 May 2006, In : Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid
Malle, E., Marsche, G., Arnhold, J. & Davies, Michael Jonathan, Apr 2006, In : B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives
Rees, M. D. & Davies, Michael Jonathan, 8 Mar 2006, In : Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides
Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In : Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Actions of ultraviolet light on cellular structures
Pattison, D. I. & Davies, Michael Jonathan, 2006, In : E X S. 96, p. 131-57 27 p.Research output: Contribution to journal › Journal article › Research
- 2005
- Published
Diabetes screening anxiety and beliefs
Skinner, Timothy, Davies, Michael Jonathan, Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In : Diabetic Medicine. 22, 11, p. 1497-1502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In : Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation
Rees, M. D., Pattison, D. I. & Davies, Michael Jonathan, 1 Oct 2005, In : Biochemical Journal. 391, Pt 1, p. 125-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In : Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function
Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In : Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers
Birinyi-Strachan, L. C., Davies, Michael Jonathan, Lewis, R. J. & Nicholson, G. M., Oct 2005, In : Neuropharmacology. 49, 5, p. 669-86 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein oxidation injury occurs during pediatric cardiopulmonary bypass
Sheil, M. L., Luxford, C., Davies, Michael Jonathan, Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In : Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins
Zeng, J. & Davies, Michael Jonathan, Aug 2005, In : Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus
Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Jul 2005, In : Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Guanine-specific DNA damage induced by gamma-irradiated histone
Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael Jonathan & Kawanishi, S., 15 Jun 2005, In : Biochemical Journal. 388, Pt 3, p. 813-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation
Pattison, D. I. & Davies, Michael Jonathan, 17 May 2005, In : Biochemistry. 44, 19, p. 7378-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells
Brown, B. E., Dean, R. T. & Davies, Michael Jonathan, Feb 2005, In : Diabetologia. 48, 2, p. 361-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The oxidative environment and protein damage
Davies, Michael Jonathan, 17 Jan 2005, In : B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
Protein-bound kynurenine is a photosensitizer of oxidative damage
Parker, N. R., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., 1 Nov 2004, In : Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates
Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides
Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 241-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress
Pattison, D. I. & Davies, Michael Jonathan, 27 Apr 2004, In : Biochemistry. 43, 16, p. 4799-809 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protective mechanisms against peptide and protein peroxides generated by singlet oxygen
Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Feb 2004, In : Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactive species formed on proteins exposed to singlet oxygen
Davies, Michael Jonathan, Jan 2004, In : Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper
Stadler, N., Lindner, R. A. & Davies, Michael Jonathan, 2004, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EPR spin trapping of protein radicals
Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products
Headlam, H. A. & Davies, Michael Jonathan, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Hypochlorite-induced oxidation of amino acids, peptides and proteins
Hawkins, C. L., Pattison, D. I. & Davies, Michael Jonathan, Dec 2003, In : Amino Acids. 25, 3-4, p. 259-74 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fragmentation of extracellular matrix by hypochlorous acid
Woods, A. A. & Davies, Michael Jonathan, 15 Nov 2003, In : Biochemical Journal. 376, Pt 1, p. 219-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation
Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 12 Nov 2003, In : Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles
Knott, H. M., Brown, B. E., Davies, Michael Jonathan & Dean, R. T., Sep 2003, In : European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Singlet oxygen-mediated damage to proteins and its consequences
Davies, Michael Jonathan, 6 Jun 2003, In : Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radical chemistry of epigallocatechin gallate and its relevance to protein damage
Hagerman, A. E., Dean, R. T. & Davies, Michael Jonathan, 1 Jun 2003, In : Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima
Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan & Smith, N. C., Jun 2003, In : Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, Apr 2003, In : Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photo-oxidation of cells generates long-lived intracellular protein peroxides
Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Mar 2003, In : Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques
Woods, A. A., Linton, S. M. & Davies, Michael Jonathan, 1 Mar 2003, In : Biochemical Journal. 370, Pt 2, p. 729-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals
Headlam, H. A. & Davies, Michael Jonathan, 1 Jan 2003, In : Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The retina: oxidative stress and diabetes
van Reyk, D. M., Gillies, M. C. & Davies, Michael Jonathan, 2003, In : Redox Report (Online). 8, 4, p. 187-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides
Hampton, M. B., Morgan, P. E. & Davies, Michael Jonathan, 11 Sep 2002, In : FEBS letters. 527, 1-3, p. 289-92 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s
Pattison, D. I., Dean, R. T. & Davies, Michael Jonathan, 1 Aug 2002, In : Toxicology. 177, 1, p. 23-37 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation
Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In : Biochemical Journal. 365, Pt 3, p. 605-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products
Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Jul 2002, In : Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction between protein radicals and other biomolecules
Østdal, H., Davies, Michael Jonathan & Andersen, H. J., 15 Jul 2002, In : Free Radical Biology & Medicine. 33, 2, p. 201-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues
Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael Jonathan, Jul 2002, In : Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones
Headlam, H. A. & Davies, Michael Jonathan, 1 Jun 2002, In : Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein
Knott, H. M., Baoutina, A., Davies, Michael Jonathan & Dean, R. T., 15 Apr 2002, In : Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack
Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, Apr 2002, In : European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins
Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In : FEBS letters. 510, 1-2, p. 41-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals
Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In : Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of aliphatic amino acid alcohols in oxidized proteins
Morin, B., Fu, S., Wang, H., Davies, Michael Jonathan & Dean, R. T., 2002, In : Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of DNA damage by oxidised amino acids and proteins
Luxford, C., Dean, R. T. & Davies, Michael Jonathan, 2002, In : Biogerontology. 3, 1-2, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis
Hawkins, C. L., Brown, B. E. & Davies, Michael Jonathan, 15 Nov 2001, In : Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein oxidation and ageing
Linton, S., Davies, Michael Jonathan & Dean, R. T., Sep 2001, In : Experimental Gerontology. 36, 9, p. 1503-18 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals
Hawkins, C. L. & Davies, Michael Jonathan, Aug 2001, In : Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation and propagation of radical reactions on proteins
Hawkins, C. L. & Davies, Michael Jonathan, 2 Apr 2001, In : B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An investigation of the chromium oxidation state of a monoanionic chromium tris(catecholate) complex by X-ray absorption and EPR spectroscopies
Pattison, D. I., Levina, A., Davies, Michael Jonathan & Lay, P. A., 15 Jan 2001, In : Inorganic Chemistry. 40, 2, p. 214-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds
Pattison, D. I. & Davies, Michael Jonathan, 2001, In : Chemical Research in Toxicology. 14, 10, p. 1453-64 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity
Pattison, D. I., Davies, Michael Jonathan, Levina, A., Dixon, N. E. & Lay, P. A., 2001, In : Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photo-oxidation of proteins and its role in cataractogenesis
Davies, Michael Jonathan & Truscott, R. J., 2001, In : Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates
Davies, Michael Jonathan & Hawkins, C. L., Dec 2000, In : Free Radical Research. 33, 6, p. 719-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains
Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael Jonathan, Nov 2000, In : Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA
Luxford, C., Dean, R. T. & Davies, Michael Jonathan, Jul 2000, In : Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers
Pattison, D. I., Lay, P. A. & Davies, Michael Jonathan, 26 Jun 2000, In : Inorganic Chemistry. 39, 13, p. 2729-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract
Garner, B., Davies, Michael Jonathan & Truscott, R. J., Jan 2000, In : Experimental Eye Research. 70, 1, p. 81-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An investigation into the genotoxic species generated during reduction of chromium(VI) by catechol(amine)s
Pattison, D. I., Lay, P. A. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 2-3, p. 130-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals
Hawkins, C. L. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 1, p. 57-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive peroxides
Wright, A., Hawkins, C. L. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 2-3, p. 159-61 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Lipid oxidation in human low-density lipoprotein induced by metmyoglobin/H2O2: involvement of alpha-tocopheroxyl and phosphatidylcholine alkoxyl radicals
Witting, P. K., Willhite, C. A., Davies, Michael Jonathan & Stocker, R., Dec 1999, In : Chemical Research in Toxicology. 12, 12, p. 1173-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stable markers of oxidant damage to proteins and their application in the study of human disease
Davies, Michael Jonathan, Fu, S., Wang, H. & Dean, R. T., Dec 1999, In : Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA
Luxford, C., Morin, B., Dean, R. T. & Davies, Michael Jonathan, 15 Nov 1999, In : Biochemical Journal. 344 Pt 1, p. 125-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael Jonathan, 1 Jun 1999, In : Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?
Ostdal, H., Andersen, H. J. & Davies, Michael Jonathan, 1 Feb 1999, In : Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myoglobin-induced oxidative damage: evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants
Irwin, J. A., Ostdal, H. & Davies, Michael Jonathan, 1 Feb 1999, In : Archives of Biochemistry and Biophysics. 362, 1, p. 94-104 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
Hazell, L. J., Davies, Michael Jonathan & Stocker, R., 1999, In : Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation
Morin, B., Bubb, W. A., Davies, Michael Jonathan, Dean, R. T. & Fu, S., Nov 1998, In : Chemical Research in Toxicology. 11, 11, p. 1265-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing
Park, J. I., Grant, C. M., Davies, Michael Jonathan & Dawes, I. W., 4 Sep 1998, In : The Journal of Biological Chemistry. 273, 36, p. 22921-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
Fu, S., Davies, Michael Jonathan, Stocker, R. & Dean, R. T., 1 Aug 1998, In : Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael Jonathan, 15 Jun 1998, In : Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation
Hawkins, C. L. & Davies, Michael Jonathan, Jun 1998, In : Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photodynamically generated bovine serum albumin radicals: evidence for damage transfer and oxidation at cysteine and tryptophan residues
Silvester, J. A., Timmins, G. S. & Davies, Michael Jonathan, 15 Mar 1998, In : Free Radical Biology & Medicine. 24, 5, p. 754-66 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage
Morin, B., Davies, Michael Jonathan & Dean, R. T., 15 Mar 1998, In : Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin
Silvester, J. A., Timmins, G. S. & Davies, Michael Jonathan, 15 Feb 1998, In : Archives of Biochemistry and Biophysics. 350, 2, p. 249-58 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes
Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael Jonathan, 1998, In : Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite
Thomas, S. R., Davies, Michael Jonathan & Stocker, R., 1998, In : Chemical Research in Toxicology. 11, 5, p. 484-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
A kinetic and ESR investigation of iron(II) oxalate oxidation by hydrogen peroxide and dioxygen as a source of hydroxyl radicals
Park, J. S., Wood, P. M., Davies, Michael Jonathan, Gilbert, B. C. & Whitwood, A. C., Nov 1997, In : Free Radical Research. 27, 5, p. 447-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absence of synproportionation between oxy and ferryl leghemoglobin. off
Mathieu, C., Swaraj, K., Davies, Michael Jonathan, Trinchant, J. C. & Puppo, A., Aug 1997, In : Free Radical Research. 27, 2, p. 165-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?
Hawkins, C. L. & Davies, Michael Jonathan, 27 Feb 1997, In : B B A - Reviews on Cancer. 1360, 1, p. 84-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biochemistry and pathology of radical-mediated protein oxidation
Dean, R. T., Fu, S., Stocker, R. & Davies, Michael Jonathan, 1997, In : Biochemical Journal. 324 ( Pt 1), p. 1-18 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage
Moreau, S., Davies, Michael Jonathan, Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In : The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage
Davies, Michael Jonathan, 1 Dec 1996, In : Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benzoyl peroxide-induced damage to DNA and its components: direct evidence for the generation of base adducts, sugar radicals, and strand breaks
Hazlewood, C. & Davies, Michael Jonathan, 1 Aug 1996, In : Archives of Biochemistry and Biophysics. 332, 1, p. 79-91 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte
Murphy, P. G., Davies, Michael Jonathan, Columb, M. O. & Stratford, N., Apr 1996, In : British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias
Collis, C. S., Rice-Evans, C. & Davies, Michael Jonathan, Apr 1996, In : International Journal of Biochemistry & Cell Biology. 28, 4, p. 405-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Xanthine oxidase activity and free radical generation in patients with sepsis syndrome
Galley, H. F., Davies, Michael Jonathan & Webster, N. R., 1996, In : Critical Care Medicine. 24, 10, p. 1649-53 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species
Moreau, S., Davies, Michael Jonathan & Puppo, A., 16 Aug 1995, In : Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
A hydrogen-donating monohydroxamate scavenges ferryl myoglobin radicals
Cooper, C. E., Green, E. S., Rice-Evans, C. A., Davies, Michael Jonathan & Wrigglesworth, J. M., Apr 1994, In : Free Radical Research. 20, 4, p. 219-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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