Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. Published

    Radical chemistry of epigallocatechin gallate and its relevance to protein damage

    Hagerman, A. E., Dean, R. T. & Davies, Michael Jonathan, 1 Jun 2003, In : Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Identification and characterization of protein cross-links induced by oxidative reactions

    Hägglund, Per Mårten, Mariotti, M. & Davies, Michael Jonathan, 2018, In : Expert Review of Proteomics. 15, 8, p. 665-681

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides

    Hampton, M. B., Morgan, P. E. & Davies, Michael Jonathan, 11 Sep 2002, In : FEBS letters. 527, 1-3, p. 289-92 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma

    Havelund, J. F., Wojdyla, K. I., Davies, Michael Jonathan, Jensen, O. N., Møller, I. M. & Rogowska-Wrzesinska, A., 6 Mar 2017, In : Journal of Proteomics. 156, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, Jun 1998, In : Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals

    Hawkins, C. L. & Davies, Michael Jonathan, Aug 2001, In : Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Generation and propagation of radical reactions on proteins

    Hawkins, C. L. & Davies, Michael Jonathan, 2 Apr 2001, In : B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals

    Hawkins, C. L. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 1, p. 57-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?

    Hawkins, C. L. & Davies, Michael Jonathan, 27 Feb 1997, In : B B A - Reviews on Cancer. 1360, 1, p. 84-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, 1 Jun 1999, In : Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Hypochlorite-induced oxidation of amino acids, peptides and proteins

    Hawkins, C. L., Pattison, D. I. & Davies, Michael Jonathan, Dec 2003, In : Amino Acids. 25, 3-4, p. 259-74 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis

    Hawkins, C. L., Brown, B. E. & Davies, Michael Jonathan, 15 Nov 2001, In : Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, 15 Jun 1998, In : Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Detection, identification, and quantification of oxidative protein modifications

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Journal of Biological Chemistry. 294, 51, p. 19683-19708

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals

    Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In : Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation

    Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In : Biochemical Journal. 365, Pt 3, p. 605-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

    Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In : Biochemical Journal. 416, 3, p. 441-52 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In : Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation

    Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In : Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In : FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In : Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Detection and characterisation of radicals in biological materials using EPR methodology

    Hawkins, Clare Louise & Davies, Michael Jonathan, Feb 2014, In : B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins

    Hazell, L. J., Davies, Michael Jonathan & Stocker, R., 1999, In : Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Benzoyl peroxide-induced damage to DNA and its components: direct evidence for the generation of base adducts, sugar radicals, and strand breaks

    Hazlewood, C. & Davies, Michael Jonathan, 1 Aug 1996, In : Archives of Biochemistry and Biophysics. 332, 1, p. 79-91 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains

    Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael Jonathan, Nov 2000, In : Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones

    Headlam, H. A. & Davies, Michael Jonathan, 1 Jun 2002, In : Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals

    Headlam, H. A. & Davies, Michael Jonathan, 1 Jan 2003, In : Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products

    Headlam, H. A. & Davies, Michael Jonathan, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides

    Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael Jonathan, 1 May 2006, In : Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences

    Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael Jonathan & Spickett, C. M., Apr 2015, In : Free Radical Research. 49, 4, p. 347-73 27 p.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation

    Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In : Free Radical Biology and Medicine. 153, p. 12-16 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins: [Meeting Abstract]

    Ignasiak-Kciuk, M., Shashikadze, B., Frackowiak, K., Gamon, Luke Francis, Davies, Michael Jonathan & Marciniak, B., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S30-S30 89.

    Research output: Contribution to journalConference articleResearchpeer-review

  34. Published

    Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space

    Indo, H. P., Majima, H. J., Terada, M., Suenaga, S., Tomita, K., Yamada, S., Higashibata, A., Ishioka, N., Kanekura, T., Nonaka, I., Hawkins, Clare Louise, Davies, Michael Jonathan, Clair, D. K. S. & Mukai, C., 16 Dec 2016, In : Scientific Reports. 6, 10 p., 39015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function

    Indo, H. P., Hawkins, Clare Louise, Nakanishi, I., Matsumoto, K., Matsui, H., Suenaga, S., Davies, Michael Jonathan, St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Vol. 240. p. 439-456 18 p. (Handbook of Experimental Pharmacology, Vol. 240).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  36. Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion

    Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael Jonathan, Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In : Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Myoglobin-induced oxidative damage: evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants

    Irwin, J. A., Ostdal, H. & Davies, Michael Jonathan, 1 Feb 1999, In : Archives of Biochemistry and Biophysics. 362, 1, p. 94-104 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

    Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : P L o S One. 11, 12, 16 p., e0168844.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): implications for foam cell formation in atherosclerosis

    Ismael, F. O., Proudfoot, J. M., Brown, B. E., van Reyk, D. M., Croft, K. D., Davies, Michael Jonathan & Hawkins, C. L., May 2015, In : Archives of Biochemistry and Biophysics. 573, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Competitive kinetics as a tool to determine rate constants for reduction of ferrylmyoglobin by food components

    Jongberg, S., Lund, Marianne N., Pattison, D. I., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2016, In : Food Chemistry. 199, p. 36-41 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Competitive reduction of perferrylmyoglobin radicals by protein thiols and plant phenols

    Jongberg, S., Lund, Marianne N., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2014, In : Journal of Agricultural and Food Chemistry. 62, 46, p. 11279-11288 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}

    Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael Jonathan & Siebuhr, A. S., 2019, In : Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.

    Research output: Contribution to journalConference articleResearch

  43. Biomarkers of oxidative stress study V: ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine

    Kadiiska, M. B., Basu, S., Brot, N., Cooper, C., Saari Csallany, A., Davies, Michael Jonathan, George, M. M., Murray, D. M., Jackson Roberts, L., Shigenaga, M. K., Sohal, R. S., Stocker, R., Van Thiel, D. H., Wiswedel, I., Hatch, G. E. & Mason, R. P., Aug 2013, In : Free Radical Biology & Medicine. 61, p. 408-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides

    Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2014, In : Free Radical Biology & Medicine. 70, p. 96-105 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols

    Karimi, M., Crossett, B., Cordwell, S. J., Pattison, David & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 154, p. 62-74 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability

    Karimi, M., Ignasiak, M. T., Chan, B., Croft, A. K., Radom, L., Schiesser, C. H., Pattison, D. I. & Davies, Michael Jonathan, 12 Dec 2016, In : Scientific Reports. 6, 12 p., 38572.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Computational design of effective, bioinspired HOCl antioxidants: the role of intramolecular Cl+ and H+ shifts

    Karton, A., O'Reilly, R. J., Pattison, D. I., Davies, Michael Jonathan & Radom, L., 21 Nov 2012, In : Journal of the American Chemical Society. 134, 46, p. 19240-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Mechanistic view of iodide in oxidative stress: [Meeting Abstract]

    Kciuk, M. I., Davies, Michael Jonathan & Marciniak, B., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S122-S122 P-254.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid

    Kennett, E. C. & Davies, Michael Jonathan, 1 Sep 2008, In : Free Radical Biology & Medicine. 45, 5, p. 716-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Mechanisms and consequences of oxidative damage to extracellular matrix

    Kennett, E. C., Chuang, Christine, Degendorfer, G., Whitelock, J. M. & Davies, Michael Jonathan, Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1279-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism

    Kennett, E. C. & Davies, Michael Jonathan, 15 Apr 2007, In : Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation

    Kennett, E. C. & Davies, Michael Jonathan, 15 Aug 2009, In : Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains

    Kennett, E. C., Rees, M. D., Malle, E., Hammer, A., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jul 2010, In : Free Radical Biology & Medicine. 49, 2, p. 282-93 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017)

    Khramtsov, V. V. & Davies, Michael Jonathan, 2018, In : Free Radical Research. 52, 3, p. 305-306

    Research output: Contribution to journalEditorialResearch

  55. Published

    Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes: Baseline data from the DESMOND randomized controlled trial

    Khunti, K., Skinner, Timothy, Heller, S., Carey, M. E., Dallosso, H. M. & Davies, Michael Jonathan, 1 Dec 2008, In : Diabetic Medicine. 25, 12, p. 1454-1461 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care

    Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael Jonathan, 9 Jun 2012, In : BMJ (Online). 344, 7860, e2333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study

    Khunti, K., Taub, N., Tringham, J., Jarvis, J., Farooqi, A., Skinner, Timothy & Davies, Michael Jonathan, 1 Apr 2010, In : Primary Care Diabetes. 4, 1, p. 25-32 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice

    Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael Jonathan, May 2015, In : Atherosclerosis. 240, 1, p. 234-241 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein

    Knott, H. M., Baoutina, A., Davies, Michael Jonathan & Dean, R. T., 15 Apr 2002, In : Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles

    Knott, H. M., Brown, B. E., Davies, Michael Jonathan & Dean, R. T., Sep 2003, In : European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations

    Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 15 Apr 2010, In : Biochemical Pharmacology. 79, 8, p. 1156-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1

    Kovacevic, Z., Sahni, S., Lok, K. H., Davies, Michael Jonathan, Wink, D. A. & Richardson, D. R., May 2017, In : B B A - Reviews on Cancer. 1861, 5 Pt A, p. 995-999 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  63. Published

    Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin

    Krämer, Anna Carola, Torreggiani, A. & Davies, Michael Jonathan, 2017, In : Journal of Agricultural and Food Chemistry. 65, 47, p. 10258-10269 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin

    Krämer, Anna Carola & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Key role of cysteine residues and sulfenic acids in thermal- and H2O2-mediated modification of β-lactoglobulin

    Krämer, Anna Carola, Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael Jonathan, 2016, In : Free Radical Biology & Medicine. 97, 8, p. 544–555 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Key role of cysteine residues in thermal- and H2O2-mediated modification of beta-lactoglobulin

    Krämer, Anna Carola, Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael Jonathan, 2016, In : Free Radical Biology & Medicine. 96, Suppl. 1, p. S16 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  67. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals

    Lam, M. A., Pattison, D. I., Bottle, S. E., Keddie, D. J. & Davies, Michael Jonathan, Nov 2008, In : Chemical Research in Toxicology. 21, 11, p. 2111-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links

    Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2008, In : Biochemical Journal. 410, 3, p. 565-574 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

    Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael Jonathan, 15 Aug 2010, In : Biochemical Journal. 430, 1, p. 161-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites

    Leinisch, F., Mariotti, M., Andersen, Sofie Hagel, Lindemose, S., Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael Jonathan, 2020, In : Scientific Reports. 10, 1, 11 p., 3106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues

    Leinisch, F., Mariotti, M., Rykaer, M., López-Alarcón, C., Hägglund, Per Mårten & Davies, Michael Jonathan, Nov 2017, In : Free Radical Biology & Medicine. 112, p. 240-252 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals

    Leinisch, F., Mariotti, M., Hägglund, Per Mårten & Davies, Michael Jonathan, Oct 2018, In : Free Radical Biology and Medicine. 126, p. 73-86

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease

    Leung, C., Herath, C. B., Jia, Z., Andrikopoulos, S., Brown, B. E., Davies, Michael Jonathan, Rivera, L. R., Furness, J. B., Forbes, J. M. & Angus, P. W., 21 Sep 2016, In : World Journal of Gastroenterology. 22, 35, p. 8026-8040 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Quinone-induced protein modifications: kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins

    Li, Y., Jongberg, S., Andersen, Mogens Larsen, Davies, Michael Jonathan & Lund, Marianne N., 2016, In : Free Radical Biology & Medicine. 97, p. 148-157 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Protein oxidation and ageing

    Linton, S., Davies, Michael Jonathan & Dean, R. T., Sep 2001, In : Experimental Gerontology. 36, 9, p. 1503-18 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells

    Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael Jonathan & Hawkins, Clare Louise, Dec 2013, In : Free Radical Biology & Medicine. 65, p. 1352-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

    Lloyd, M. M., van Reyk, D. M., Davies, Michael Jonathan & Hawkins, Clare Louise, 1 Sep 2008, In : Biochemical Journal. 414, 2, p. 271-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

    Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael Jonathan, Iozzo, R. V. & Whitelock, J. M., Apr 2014, In : Matrix Biology. 35, p. 112-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Nitration alters laminin polymerization: [Meeting Abstract]

    Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, S1, p. S127-S127 P-271.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  80. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

    Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 2019, In : Redox Biology. 24, UNSP 101226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages

    Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : Free Radical Biology & Medicine. 94, p. 88-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

    Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael Jonathan, Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In : Journal of Endocrinology. 233, 3, p. 369-379 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, Jul 2000, In : Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA

    Luxford, C., Morin, B., Dean, R. T. & Davies, Michael Jonathan, 15 Nov 1999, In : Biochemical Journal. 344 Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Induction of DNA damage by oxidised amino acids and proteins

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, 2002, In : Biogerontology. 3, 1-2, p. 95-102 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

    Mai, K., Smith, N. C., Feng, Z., Katrib, M., Slapeta, J., Slapetova, I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan, Zhang, X., Norton, R. S. & Belli, S. I., Sep 2011, In : International Journal for Parasitology (Online). 41, 11, p. 1157-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Chasing Great Paths of Helmut “Oxidative Stress” Sies

    Majima, H., Indo, H., Nakanishi, I., Suenaga, S., Matsumoto, K., Matsui, H., Minamiyami, Y., Ichikawa, H., Yen, H., Hawkins, C., Davies, Michael Jonathan, Ozawa, T. & St. Clair, D., 2016, In : Archives of Biochemistry and Biophysics. 595, p. 54-60 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid

    Malle, E., Marsche, G., Arnhold, J. & Davies, Michael Jonathan, Apr 2006, In : B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

    Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 2018, In : Journal of Proteome Research. 17, 6, p. 2017-2027

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Absence of synproportionation between oxy and ferryl leghemoglobin. off

    Mathieu, C., Swaraj, K., Davies, Michael Jonathan, Trinchant, J. C. & Puppo, A., Aug 1997, In : Free Radical Research. 27, 2, p. 165-71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes

    Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael Jonathan, 1998, In : Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation

    Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, Michael Jonathan, Beattie, J. H. & Galley, H. F., 2015, In : British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage

    Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael Jonathan, 15 Mar 2008, In : Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis

    Moheimani, F., Morgan, P. E., van Reyk, D. M. & Davies, Michael Jonathan, Jun 2010, In : B B A - Reviews on Cancer. 1802, 6, p. 561-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins

    Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael Jonathan, 2011, In : Journal of Diabetes Research. 2011, p. 851280

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis

    Moheimani, F., Kim, C. H. J., Rahmanto, A. S., van Reyk, D. M. & Davies, Michael Jonathan, Jul 2012, In : Atherosclerosis. 223, 1, p. 144-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species

    Moreau, S., Davies, Michael Jonathan & Puppo, A., 16 Aug 1995, In : Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage

    Moreau, S., Davies, Michael Jonathan, Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In : The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase

    Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael Jonathan, 27 Mar 2015, In : Free Radical Research. 49, 6, p. 743-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Jul 2005, In : Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205