Michael Jonathan Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3, 2200 København N, 12.6, Building: 30
Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides
Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In : Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between depression and health-related quality of life in people with type 2 diabetes: A systematic literature review
Ali, S., Stone, M., Skinner, Timothy, Robertson, N., Davies, Michael Jonathan & Khunti, K., 1 Feb 2010, In : Diabetes/Metabolism Research and Reviews. 26, 2, p. 75-89 15 p.Research output: Contribution to journal › Review › Research › peer-review
Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals: role of oxidizable amino acid residues
Arenas, A., López-Alarcón, C., Kogan, M., Lissi, E., Davies, Michael Jonathan & Silva, E., 18 Jan 2013, In : Chemical Research in Toxicology. 26, 1, p. 67-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between anxiety and measures of glycaemia in a population-based diabetes screening programme
Aujla, N., Davies, Michael Jonathan, Skinner, Timothy, Gray, L. J., Webb, D. R., Srinivasan, Balaji & Khunti, K., 1 Jul 2011, In : Diabetic Medicine. 28, 7, p. 785-788 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: A comparison of two screening tools
Aujla, N., Skinner, Timothy, Khunti, K. & Davies, Michael Jonathan, 1 Aug 2010, In : Diabetic Medicine. 27, 8, p. 896-905 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus
Aujla, N., Abrams, K. R., Davies, Michael Jonathan, Taub, N., Skinner, Timothy & Khunti, K., 9 Nov 2009, In : PLoS ONE. 4, 11, e7755.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism
Avila, F., Ravello, N., Zanocco, A. L., Gamon, Luke Francis, Davies, Michael Jonathan & Silva, E., 2019, In : Free Radical Biology and Medicine. 141, p. 103-114Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates
Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Mar 2012, In : Free Radical Biology & Medicine. 52, 6, p. 1075-85 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima
Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan & Smith, N. C., Jun 2003, In : Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers
Birinyi-Strachan, L. C., Davies, Michael Jonathan, Lewis, R. J. & Nicholson, G. M., Oct 2005, In : Neuropharmacology. 49, 5, p. 669-86 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination
Möllers Blossom, Benedikt, Russo, D. A., Singh, Raushan Kumar, Van Oort, B., Keller, Malene Billeskov, Simonsen, Tor Ivan, Perzon, A., Gamon, Luke Francis, Davies, Michael Jonathan, Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In : ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants
Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael Jonathan, Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In : Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
Borges, E. L., Ignasiak, M. T., Velichenko, Y., Perin, G., Hutton, C. A., Davies, Michael Jonathan & Schiesser, C. H., 25 Mar 2018, In : Chemical Communications. 54, 24, p. 2990-2993Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells
Brown, B. E., Dean, R. T. & Davies, Michael Jonathan, Feb 2005, In : Diabetologia. 48, 2, p. 361-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice
Brown, B. E., Kim, C. H. J., Torpy, F. R., Bursill, C. A., McRobb, L. S., Heather, A. K., Davies, Michael Jonathan & van Reyk, D. M., Feb 2014, In : Atherosclerosis. 232, 2, p. 403-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages
Brown, B. E., Nobecourt, E., Zeng, J., Jenkins, A. J., Rye, K. & Davies, Michael Jonathan, 2013, In : PLOS ONE. 8, 5, p. e65430Research output: Contribution to journal › Journal article › Research › peer-review
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, Mar 2007, In : F E B S Journal. 274, 6, p. 1530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis: [Meeting Absract]
Cai, H., Chuang, Christine & Davies, Michael Jonathan, 2018, In : International Journal of Experimental Pathology. 99, 6, p. A24-A24Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells
Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 134, p. 526-536Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In : Scientific Reports. 13 p., 666.Research output: Contribution to journal › Journal article › Research › peer-review
Increasing capacity to deliver diabetes self-management education: Results of the DESMOND lay educator non-randomized controlled equivalence trial
Carey, M. E., Mandalia, P. K., Daly, H., Gray, L. J., Hale, R., Martin Stacey, L., Taub, N., Skinner, Timothy, Stone, M., Heller, S., Khunti, K. & Davies, Michael Jonathan, 1 Jan 2014, In : Diabetic Medicine. 31, 11, p. 1431-1438 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants
Carroll, L., Davies, Michael Jonathan & Pattison, D. I., 2015, In : Free Radical Research. 49, 6, p. 750-767 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 132-142 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, 2017, In : Redox Biology. 12, p. 872-882 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interaction kinetics of selenium -containing compounds with oxidants
Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael Jonathan, 2020, In : Free Radical Biology and Medicine. 155, p. 58-68Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidant-induced glutathionylation at protein disulfide bonds
Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 20 Nov 2020, In : Free Radical Biology and Medicine. 160, p. 513-525 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Apr 2018, In : Free Radical Biology and Medicine. 118, p. 126-136Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, Jul 2015, In : Free Radical Biology & Medicine. 84, p. 279-288 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines
Carroll, L., Karton, A., Radom, L., Davies, Michael Jonathan & Pattison, D. I., 2019, In : Chemical Research in Toxicology. 32, 3, p. 513-525 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins
Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 395-405 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypobromous acid and bromamine production by neutrophils and modulation by superoxide
Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael Jonathan, 1 Feb 2009, In : Biochemical Journal. 417, 3, p. 773-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models
Chen, Z., Kondrashina, A., Greco, Ines, Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael Jonathan, 2019, In : Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula
Chen, Z., Leinisch, F., Greco, Ines, Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 68-81Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula: [Meeting Abstract]
Chen, Z., Leinisch, F., Greco, Ines, Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, Supplement 1, p. S47 1 p., P-8.Research output: Contribution to journal › Conference abstract in journal › Research
Oxidation and modification of extracellular matrix and its role in disease
Chuang, Christine, Degendorfer, G. & Davies, Michael Jonathan, Sep 2014, In : Free Radical Research. 48, 9, p. 970-89 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells
Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael Jonathan, 15 Apr 2014, In : Biochemical Journal. 459, 2, p. 313-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias
Collis, C. S., Rice-Evans, C. & Davies, Michael Jonathan, Apr 1996, In : International Journal of Biochemistry & Cell Biology. 28, 4, p. 405-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells
Cook, N. L., Viola, H. M., Sharov, V. S., Hool, L. C., Schöneich, C. & Davies, Michael Jonathan, 1 Mar 2012, In : Free Radical Biology & Medicine. 52, 5, p. 951-61 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins
Cook, N. L., Pattison, D. I. & Davies, Michael Jonathan, 1 Dec 2012, In : Free Radical Biology & Medicine. 53, 11, p. 2072-80 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues
Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael Jonathan, 1 Jan 2016, In : Free Radical Biology & Medicine. 90, p. 195-205 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A hydrogen-donating monohydroxamate scavenges ferryl myoglobin radicals
Cooper, C. E., Green, E. S., Rice-Evans, C. A., Davies, Michael Jonathan & Wrigglesworth, J. M., Apr 1994, In : Free Radical Research. 20, 4, p. 219-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study
Crasto, W., Jarvis, J., Khunti, K., Skinner, Timothy, Gray, L. J., Brela, J., Troughton, J., Daly, H., Lawrence, I. G., McNally, P. G., Carey, M. E. & Davies, Michael Jonathan, 1 Sep 2011, In : Diabetes Research and Clinical Practice. 93, 3, p. 328-336 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation
Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael Jonathan, 27 Jul 2011, In : Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching
David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Redox Biology. 24, 9 p., 101207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial
Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In : BMJ. 336, 7642, p. 491-495 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The DESMOND educational intervention
Davies, Michael Jonathan, Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In : Chronic Illness. 4, 1, p. 38-40 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Tempus fugit horizontal ellipsis
Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 1-1Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
Davies, Michael Jonathan, 2021, In : Pharmacology and Therapeutics. 218, 23 p., 107685.Research output: Contribution to journal › Review › Research › peer-review
- Published
1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule
Davies, Michael Jonathan & Schiesser, C. H., 2019, In : New Journal of Chemistry. 43, 25, p. 9759-9765Research output: Contribution to journal › Review › Research › peer-review
- Published
Peroxides and protein oxidation
Davies, Michael Jonathan, 1 Jan 2017, Hydrogen Peroxide Metabolism in Health and Disease. CRC Press, p. 101-124Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Stable markers of oxidant damage to proteins and their application in the study of human disease
Davies, Michael Jonathan, Fu, S., Wang, H. & Dean, R. T., Dec 1999, In : Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein oxidation and peroxidation
Davies, Michael Jonathan, 2016, In : Biochemical Journal. 473, 7, p. 805-825 21 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Sulfur and selenium in oxidation protection
Davies, Michael Jonathan, 2015, In : La chimica e l’industria, Chimica & Materiali. 2015, 6, p. 50-54Research output: Contribution to journal › Review › Research › peer-review
Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention
Davies, Michael Jonathan, Jan 2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 8-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photo-oxidation of proteins and its role in cataractogenesis
Davies, Michael Jonathan & Truscott, R. J., 2001, In : Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactive species formed on proteins exposed to singlet oxygen
Davies, Michael Jonathan, Jan 2004, In : Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease
Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants & Redox Signaling. 32, 13, p. 957-981Research output: Contribution to journal › Review › Research › peer-review
- Published
Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage
Davies, Michael Jonathan, 1 Dec 1996, In : Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods
Davies, Michael Jonathan, 2016, In : Methods. 109, p. 21-30 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
The oxidative environment and protein damage
Davies, Michael Jonathan, 17 Jan 2005, In : B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EPR spin trapping of protein radicals
Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mammalian heme peroxidases: from molecular mechanisms to health implications
Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates
Davies, Michael Jonathan & Hawkins, C. L., Dec 2000, In : Free Radical Research. 33, 6, p. 719-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Singlet oxygen-mediated damage to proteins and its consequences
Davies, Michael Jonathan, 6 Jun 2003, In : Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Free Radical Research origins
Davies, Michael Jonathan, Jan 2012, In : Free Radical Research. 46, 1, p. 1Research output: Contribution to journal › Journal article › Research
- Published
Biochemistry and pathology of radical-mediated protein oxidation
Dean, R. T., Fu, S., Stocker, R. & Davies, Michael Jonathan, 1997, In : Biochemical Journal. 324 ( Pt 1), p. 1-18 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxynitrite-mediated oxidation of plasma fibronectin
Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael Jonathan, Aug 2016, In : Free Radical Biology & Medicine. 97, p. 602-615 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin
Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael Jonathan, Dec 2015, In : Free Radical Biology & Medicine. 89, p. 721-733 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]
Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael Jonathan, 1 Feb 2018, In : Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides
Dremina, E. S., Sharov, V. S., Davies, Michael Jonathan & Schöneich, C., Oct 2007, In : Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis
Dunn, L. L., Simpson, P. J. L., Prosser, H. C., Lecce, L., Yuen, G. S. C., Buckle, A., Sieveking, D. P., Vanags, L. Z., Lim, P. R., Chow, R. W. Y., Lam, Y. T., Clayton, Z., Bao, S., Davies, Michael Jonathan, Stadler, N., Celermajer, D. S., Stocker, R., Bursill, C. A., Cooke, J. P. & Ng, M. K. C., Feb 2014, In : Diabetes. 63, 2, p. 675-87 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]
Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.Research output: Contribution to journal › Conference abstract in journal › Research
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The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function
Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael Jonathan & López-Alarcón, C., Nov 2017, In : Free Radical Biology and Medicine. 112, p. 60-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion
Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In : RSC Advances. 10, 43, p. 25786-25800 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]
Flouda, Konstantina, Davies, Michael Jonathan & Hawkins, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues
Flouda, Konstantina, Gammelgaard, Bente, Davies, Michael Jonathan & Hawkins, Clare Louise, May 2021, In : Redox Biology. 41, 101873.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage
Flouda, Konstantina, Mercer, J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2021, In : Free Radical Biology & Medicine. 166, p. 165-177Research output: Contribution to journal › Journal article › Research › peer-review
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Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification
Forman, H. J., Davies, Michael Jonathan, Krämer, Anna Carola, Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In : Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
Fu, S., Davies, Michael Jonathan, Stocker, R. & Dean, R. T., 1 Aug 1998, In : Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent
Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael Jonathan & Lopez-Alarcon, C., 1 Aug 2018, In : Food Chemistry. 256, p. 119-128Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals
Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2016, In : RSC Advances. 6, 63, p. 57948-57955 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aggregation of alpha- and beta- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation
Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Escobar, E., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 20 Aug 2018, In : Free Radical Biology and Medicine. 124, p. 176-188Research output: Contribution to journal › Journal article › Research › peer-review
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Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks
Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2020, In : Free Radical Biology and Medicine. 152, p. 61-73Research output: Contribution to journal › Journal article › Research › peer-review
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Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]
Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan
Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 143, p. 375-386Research output: Contribution to journal › Journal article › Research › peer-review
Guanine-specific DNA damage induced by gamma-irradiated histone
Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael Jonathan & Kawanishi, S., 15 Jun 2005, In : Biochemical Journal. 388, Pt 3, p. 813-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses
Gad, N. A., Mizdrak, J., Pattison, D. I., Davies, Michael Jonathan, Truscott, R. J. W. & Jamie, J. F., Feb 2014, In : Investigative Ophthalmology & Visual Science. 55, 2, p. 849-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Xanthine oxidase activity and free radical generation in patients with sepsis syndrome
Galley, H. F., Davies, Michael Jonathan & Webster, N. R., 1996, In : Critical Care Medicine. 24, 10, p. 1649-53 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction
Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael Jonathan, Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In : American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase
Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael Jonathan, 2020, In : Redox Biology. 28, 12 p., 101331.Research output: Contribution to journal › Journal article › Research › peer-review
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Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization
Gamon, Luke Francis, Guo, Chaorui, He, Jianfei, Hägglund, Per Mårten, Hawkins, Clare Louise & Davies, Michael Jonathan, Sep 2020, In : Redox Biology. 36, 9 p., 101586.Research output: Contribution to journal › Journal article › Research › peer-review
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Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]
Gamon, Luke Francis & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]
Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract
Garner, B., Davies, Michael Jonathan & Truscott, R. J., Jan 2000, In : Experimental Eye Research. 70, 1, p. 81-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Whey proteins: targets of oxidation, or mediators of redox protection
Giblin, L., Yalcin, A. S., Bicim, G., Krämer, Anna Carola, Chen, Z., Callanan, M. J., Arranz, E. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, S1, p. 1136–1152 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cost effectiveness analysis
Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M. E., Campbell, M. J., Heller, S., Khunti, K., Skinner, Timothy & Davies, Michael Jonathan, 26 Aug 2010, In : BMJ (Online). 341, 7770, c4093.Research output: Contribution to journal › Journal article › Research › peer-review
Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome
Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Jan 2011, In : Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products
Gracanin, M. & Davies, Michael Jonathan, 15 May 2007, In : Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products
Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In : Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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