Michael J. Davies

Michael J. Davies

Professor

ORCID: 0000-0002-5196-6919

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  1. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Actions of ultraviolet light on cellular structures

    Pattison, D. I. & Davies, Michael J., 2006, In: E X S. 96, p. 131-57 27 p.

    Research output: Contribution to journal › Journal article › Research

  3. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael J., 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

    Pattison, D. I., Davies, Michael J. & Hawkins, Clare Louise, Aug 2012, In: Free Radical Research. 46, 8, p. 975-95 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Enzymatic cross-linking of collagens in organ fibrosis - resolution and assessment

    Pehrsson, M., Mortensen, J. H., Manon-Jensen, T., Bay-Jensen, A., Karsdal, M. A. & Davies, Michael J., 2021, In: Expert Review of Molecular Diagnostics. 21, 10, p. 1049-1064

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC

    Perez-Hernandez, M., van Opbergen, C. J. M., Bagwan, N., Vissing, C. R., Marron-Linares, G. M., Zhang, M., Vega, E. T., Sorrentino, A., Drici, L., Sulek, K., Zhai, R., Hansen, F. B., Christensen, A. H., Boesgaard, S., Gustafsson, F., Rossing, K., Small, E. M., Davies, M. J., Rothenberg, E., Sato, P. Y. & 6 others, Cerrone, M., Jensen, Thomas Hartvig Lindkær, Qvortrup, Klaus, Bundgård, Henning, Delmar, M. & Lundby, Alicia, 2022, In: Circulation. 146, 11, p. 851-867

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3

    Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, Michael J. & Winterbourn, C. C., 1 Dec 2010, In: Biochemical Journal. 432, 2, p. 313-21 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Cardiac spheroids as promising in vitro models to study the human heart microenvironment

    Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Figtree, G. A., Davies, Michael J. & Gentile, C., 1 Aug 2017, In: Scientific Reports. 7, 12 p., 7005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Cardiac spheroid co-cultures as a novel in vitro model to study human heart microenvironment

    Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Davies, Michael J., Figtree, G. & Gentile, C., 2018, In: Journal of Pharmacological and Toxicological Methods. 93, p. 167 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  10. Published

    Oxygen Exposure and Tolerance Shapes the Cell Wall-Associated Lipids of the Skin Commensal Cutibacterium acnes

    Popa, I., Touboul, D., Andersson, T., Fuentes Lemus, Eduardo, Santerre, C., Davies, Michael J. & Lood, R., 2023, In: Microorganisms. 11, 9, 15 p., 2260.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Cellular effects of peptide and protein hydroperoxides

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 15 Apr 2010, In: Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Selenium-containing amino acids as direct and indirect antioxidants

    Rahmanto, A. S. & Davies, Michael J., Nov 2012, In: I U B M B Life. 64, 11, p. 863-71 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 30 Nov 2010, In: Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro

    Rashid, I., van Reyk, D. M. & Davies, Michael J., 6 Mar 2007, In: FEBS Letters. 581, 5, p. 1067-70 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    MODULATION OF ENDOTHELIAL CELL FUNCTION BY THE MYELOPEROXIDASE-DERIVED OXIDANT HYPOCHLOROUS ACID (HOCl) AND ITS CONTRIBUTION TO ATHEROSCLEROSIS

    Rayner, B. S., Lloyd, M. M., Summers, F. A., Davies, Michael J. & Hawkins, Clare Louise, 2014, In: Hypertension.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives

    Rees, M. D. & Davies, Michael J., 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Oxidative damage to extracellular matrix and its role in human pathologies

    Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael J., 15 Jun 2008, In: Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

    Rees, M. D., Whitelock, J. M., Malle, E., Chuang, Christine, Iozzo, R. V., Nilasaroya, A. & Davies, Michael J., Jan 2010, In: Matrix Biology. 29, 1, p. 63-73 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Degradation of extracellular matrix and its components by hypobromous acid

    Rees, M. D., McNiven, T. N. & Davies, Michael J., 15 Jan 2007, In: Biochemical Journal. 401, 2, p. 587-96 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides

    Rees, M. D., Bottle, S. E., Fairfull-Smith, K. E., Malle, E., Whitelock, J. M. & Davies, Michael J., 1 Jul 2009, In: Biochemical Journal. 421, 1, p. 79-86 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation

    Rees, M. D., Pattison, D. I. & Davies, Michael J., 1 Oct 2005, In: Biochemical Journal. 391, Pt 1, p. 125-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    M. jannaschii FtsZ, a key protein in bacterial cell division, is inactivated by peroxyl radical-mediated methionine oxidation

    Reyes, J. S., Fuentes Lemus, Eduardo, Aspée, A., Davies, Michael J., Monasterio, O. & López-Alarcón, C., 2021, In: Free Radical Biology and Medicine. 166, p. 53-66

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Peroxyl radicals modify 6-phosphogluconolactonase from Escherichia coli via oxidation of specific amino acids and aggregation which inhibits enzyme activity

    Reyes, J. S., Fuentes Lemus, Eduardo, Romero, J., Arenas, F., Fierro, A., Davies, Michael J. & López-Alarcón, C., 2023, In: Free Radical Biology and Medicine. 204, p. 118-127

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Implications of differential peroxyl radical-induced inactivation of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase for the pentose phosphate pathway

    Reyes, J. S., Fuentes Lemus, Eduardo, Figueroa, J. D., Rojas, J., Fierro, A., Arenas, F., Hägglund, Per Mårten, Davies, Michael J. & López-Alarcón, C., 2022, In: Scientific Reports. 12, 1, 19 p., 21191.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Reaction of cysteine residues with oxidized tyrosine residues mediates cross-linking of photo-oxidized casein proteins

    Rossi, C., Fuentes Lemus, Eduardo & Davies, Michael J., 2022, In: Food Chemistry. 385, 7 p., 132667.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications

    Rykær, M., Svensson, B., Davies, Michael J. & Hägglund, Per Mårten, 3 Nov 2017, In: Journal of Proteome Research. 16, 11, p. 3978-3988 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Structural Basis for Dityrosine-Mediated Inhibition of alpha-Synuclein Fibrillization

    Sahin, C., Osterlund, E. C., Osterlund, N., Costeira-Paulo, J., Pedersen, J. N., Christiansen, G., Nielsen, J., Grønnemose, A. L., Amstrup, S. K., Tiwari, M. K., Rao, R. S. P., Bjerrum, Morten Jannik, Ilag, L. L., Davies, Michael J., Marklund, E. G., Pedersen, J. S., Landreh, M., Moller, I. M., Jorgensen, T. J. D. & Otzen, D. E., 2022, In: Journal of the American Chemical Society. 144, 27, p. 11949-11954 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols

    Sauerland, M., Mertes, R., Morozzi, C., Eggler, A. L., Gamon, Luke Francis & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 169, p. 1-11 569.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Kinetic data for the reactions of alpha,beta-unsaturated aldehydes shed light on their molecular targets and biological effects

    Sauerland, M., Gamon, Luke Francis & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 596 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  32. Published

    Electrophile versus oxidant modification of cysteine residues: Kinetics as a key driver of protein modification

    Sauerland, Max Benjamin & Davies, Michael J., 30 Sep 2022, In: Archives of Biochemistry and Biophysics. 727, 10 p., 109344.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Identification of galectin-1 and other cellular targets of alpha,beta-unsaturated carbonyl compounds, including dimethylfumarate, by use of click-chemistry probes

    Sauerland, Max Benjamin, Helm, C., Lorentzen, Lasse Gøbel, Manandhar, Asmita, Ulven, Trond, Gamon, Luke Francis & Davies, Michael J., 2023, In: Redox Biology. 59, 15 p., 102560.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

    Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael J., Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In: Archives of Biochemistry and Biophysics. 689, 7 p., 108443.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Protein oxidation injury occurs during pediatric cardiopulmonary bypass

    Sheil, M. L., Luxford, C., Davies, Michael J., Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In: Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Reaction of quinones with proteins: Kinetics of adduct formation, effects on enzymatic activity and protein structure, and potential reversibility of modifications

    Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 137, p. 169-180

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone

    Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael J., 2020, In: Redox Biology. 28, 9 p., 101335 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Kinetics and biological consequences of quinone-induced protein adduction: [Meeting Abstract]

    Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S55-S55 P-34.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  39. Published

    Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]

    Shu, N., Hägglund, Per Mårten & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S9-S9 8.

    Research output: Contribution to journal › Conference abstract in journal › Research

  40. Published

    Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function: [Meeting Abstract]

    Shu, N. & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S49-S49 168.

    Research output: Contribution to journal › Conference abstract in journal › Research

  41. Published

    Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway

    Shu, N., Hägglund, Per Mårten, Cai, H., Hawkins, Clare Louise & Davies, Michael J., Jan 2020, In: Redox Biology. 29, UNSP 101400.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

    Sies, H., Belousov, V. V., Chandel, N. S., Davies, Michael J., Jones, D. P., Mann, G. E., Murphy, M. P., Yamamoto, M. & Winterbourn, C., 2022, In: Nature Reviews Molecular Cell Biology. 23, p. 499–515

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    The role of RNA oxidation in islet dysfunction in Type 2 diabetes

    Sileikaite, I., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1 , p. S37-S38

    Research output: Contribution to journal › Conference abstract in journal › Research

  44. Published

    Detrimental Actions of Chlorinated Nucleosides on the Function and Viability of Insulin-Producing Cells

    Sileikaite-Morvaközi, I., Hansen, W. H., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2023, In: International Journal of Molecular Sciences. 24, 19, 13 p., 14585.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Influence of O-2 on riboflavin-mediated photo-oxidation of lysozyme: [Meeting Abstract]

    Silva, E., Tirapegui, C., Fuentes-Lemus, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Caroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S58-S59 P-46.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  46. Published

    Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode

    Silva, E., Barrias, P., Fuentes-Lemus, E., Tirapegui, C., Aspee, A., Carroll, L., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Free Radical Biology and Medicine. 131, p. 133-143

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin

    Silvester, J. A., Timmins, G. S. & Davies, Michael J., 15 Feb 1998, In: Archives of Biochemistry and Biophysics. 350, 2, p. 249-58 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Photodynamically generated bovine serum albumin radicals: evidence for damage transfer and oxidation at cysteine and tryptophan residues

    Silvester, J. A., Timmins, G. S. & Davies, Michael J., 15 Mar 1998, In: Free Radical Biology & Medicine. 24, 5, p. 754-66 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage

    Skaff, O., Pattison, D. I., Morgan, P. E., Bachana, R., Jain, V. K., Priyadarsini, K. I. & Davies, Michael J., 1 Jan 2012, In: Biochemical Journal. 441, 1, p. 305-16 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants

    Skaff, O., Pattison, D. I. & Davies, Michael J., Dec 2007, In: Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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