Michael J. Davies

Michael J. Davies

Professor

ORCID: 0000-0002-5196-6919

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  1. Published

    Early events in copper-ion catalyzed oxidation of α-synuclein

    Tiwari, M. K., Leinisch, F., Sahin, C., Møller, I. M., Otzen, D. E., Davies, Michael J. & Bjerrum, Morten Jannik, 2018, In: Free Radical Biology & Medicine. 121, p. 38-50 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin

    Krämer, A. C. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin

    Krämer, A. C., Torreggiani, A. & Davies, Michael J., 2017, In: Journal of Agricultural and Food Chemistry. 65, 47, p. 10258-10269 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Effect of crowding, compartmentalization and nanodomains on protein modification and redox signaling – current state and future challenges

    Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 196, p. 81-92

    Research output: Contribution to journal › Review › Research › peer-review

  5. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins

    Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael J., 2011, In: Journal of Diabetes Research. 2011, p. 851280

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin

    Nielsen, L. R., Lund, Marianne N., Davies, Michael J., Nielsen, J. H. & Nielsen, S. B., 2018, In: International Dairy Journal. 79, p. 52-61 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Effect of macromolecular crowding on protein oxidation: Consequences on the rate, extent and oxidation pathways

    Fuentes Lemus, Eduardo, Reyes, J. S., Gamon, Luke Francis, López-Alarcón, C. & Davies, Michael J., 2021, In: Redox Biology. 48, 15 p., 102202.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte

    Murphy, P. G., Davies, Michael J., Columb, M. O. & Stratford, N., Apr 1996, In: British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals

    Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael J. & Radom, L., 31 Aug 2006, In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care

    Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael J., 9 Jun 2012, In: BMJ (Online). 344, 7860, e2333.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial

    Davies, Michael J., Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In: BMJ. 336, 7642, p. 491-495 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models

    Chen, Z., Kondrashina, A., Greco, I., Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings

    Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael J., 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]

    Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael J., 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  15. Published

    Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I

    Nobecourt, E., Zeng, J., Davies, Michael J., Brown, B. E., Yadav, S., Barter, P. J. & Rye, K. -., Jun 2008, In: Diabetologia. 51, 6, p. 1008-1017 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Electrophile versus oxidant modification of cysteine residues: Kinetics as a key driver of protein modification

    Sauerland, Max Benjamin & Davies, Michael J., 30 Sep 2022, In: Archives of Biochemistry and Biophysics. 727, 10 p., 109344.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction

    Gentile, C., Kesteven, S., Wu, J., Davies, Michael J., Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  18. Published

    Enzymatic cross-linking of collagens in organ fibrosis - resolution and assessment

    Pehrsson, M., Mortensen, J. H., Manon-Jensen, T., Bay-Jensen, A., Karsdal, M. A. & Davies, Michael J., 2021, In: Expert Review of Molecular Diagnostics. 21, 10, p. 1049-1064

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Ethnic differences in the prevalence and recognition of depression in a primary care population with and without type 2 diabetes

    Ali, S., Taub, N. A., Stone, M. A., Davies, Michael J., Skinner, Timothy & Khunti, K., 1 Sep 2010, Diabetologia.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  20. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Feb 2009, In: Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

    Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael J., 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael J., 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

    Fu, S., Davies, Michael J., Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins

    Zeng, J. & Davies, Michael J., Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences

    Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael J. & Spickett, C. M., Apr 2015, In: Free Radical Research. 49, 4, p. 347-73 27 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells

    Talib, J. & Davies, Michael J., 2016, In: Journal of Biological Inorganic Chemistry. 21, 3, p. 305-317 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]

    Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  28. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function

    Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael J., 1 Feb 2018, In: Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Exposure to peroxynitrite impacts the ability of anastellin to modulate the structure of extracellular matrix

    He, Jianfei, Chuang, Christine, Hawkins, Clare Louise, Davies, Michael J. & Hägglund, Per Mårten, 2023, In: Free Radical Biology and Medicine. 206, p. 83-93 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}

    Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael J. & Siebuhr, A. S., 2019, In: Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.

    Research output: Contribution to journal › Conference abstract in journal › Research

  31. Published

    Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion

    Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael J. & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins

    Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 132-142 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract

    Garner, B., Davies, Michael J. & Truscott, R. J., Jan 2000, In: Experimental Eye Research. 70, 1, p. 81-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?

    Ostdal, H., Andersen, H. J. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation

    Jiang, S., Carroll, L., Mariotti, M., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Redox Biology. 41, 16 p., 101874.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Fragmentation of extracellular matrix by hypochlorous acid

    Woods, A. A. & Davies, Michael J., 15 Nov 2003, In: Biochemical Journal. 376, Pt 1, p. 219-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Free Radical Research origins

    Davies, Michael J., Jan 2012, In: Free Radical Research. 46, 1, p. 1

    Research output: Contribution to journal › Journal article › Research

  38. Published

    Generation and propagation of radical reactions on proteins

    Hawkins, C. L. & Davies, Michael J., 2 Apr 2001, In: B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure

    Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael J. & Lund, Marianne N., 2020, In: Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Genotoxicity assessment of 1,4-anhydro-4-seleno-D-talitol (SeTal) in human liver HepG2 and HepaRG cells

    di Vito, R., Acito, M., Fatigoni, C., Schiesser, C. H., Davies, Michael J., Mangiavacchi, F., Villarini, M., Santi, C. & Moretti, M., 2023, In: Toxicology. 499, 153663.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction

    Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael J., Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles

    Knott, H. M., Brown, B. E., Davies, Michael J. & Dean, R. T., Sep 2003, In: European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages

    Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael J., Mar 2007, In: F E B S Journal. 274, 6, p. 1530-41 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells

    Brown, B. E., Dean, R. T. & Davies, Michael J., Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation

    Kennett, E. C. & Davies, Michael J., 15 Aug 2009, In: Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Guanine-specific DNA damage induced by gamma-irradiated histone

    Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael J. & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo

    Murphy, M. P., Bayir, H., Belousov, V., Chang, C. J., Davies, K. J. A., Davies, M. J., Dick, T. P., Finkel, T., Forman, H. J., Janssen-Heininger, Y., Gems, D., Kagan, V. E., Kalyanaraman, B., Larsson, N. G., Milne, G. L., Nyström, T., Poulsen, H. E., Radi, R., Van Remmen, H., Schumacker, P. T. & 5 others, Thornalley, P. J., Toyokuni, S., Winterbourn, C. C., Yin, H. & Halliwell, B., 2022, In: Nature Metabolism. 4, 6, p. 651-662

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives

    Rees, M. D. & Davies, Michael J., 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage

    Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Food Hydrocolloids. 121, 16 p., 107060.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction

    Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael J., Oct 2014, In: Free Radical Research. 48, 10, p. 1256-66 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

    Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine

    Talib, J., Pattison, D. I., Harmer, J. A., Celermajer, D. S. & Davies, Michael J., 1 Jul 2012, In: Free Radical Biology & Medicine. 53, 1, p. 20-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA

    Luxford, C., Morin, B., Dean, R. T. & Davies, Michael J., 15 Nov 1999, In: Biochemical Journal. 344 Pt 1, p. 125-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Hypobromous acid and bromamine production by neutrophils and modulation by superoxide

    Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael J., 1 Feb 2009, In: Biochemical Journal. 417, 3, p. 773-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis

    Hawkins, C. L., Brown, B. E. & Davies, Michael J., 15 Nov 2001, In: Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals

    Hawkins, Clare Louise & Davies, Michael J., Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals

    Hawkins, C. L. & Davies, Michael J., Aug 2001, In: Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael J., 15 Jun 1998, In: Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals

    Hawkins, C. L. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 1, p. 57-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Hypochlorite-induced oxidation of amino acids, peptides and proteins

    Hawkins, C. L., Pattison, D. I. & Davies, Michael J., Dec 2003, In: Amino Acids. 25, 3-4, p. 259-74 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael J., 1 Jun 1999, In: Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates

    Davies, Michael J. & Hawkins, C. L., Dec 2000, In: Free Radical Research. 33, 6, p. 719-29 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity

    Wang, Y., Hammer, A., Hoefler, G., Malle, E., Hawkins, Clare Louise, Chuang, Christine & Davies, Michael J., 2023, In: Antioxidants. 12, 2, 25 p., 420.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin

    Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael J. & Witting, P. K., 15 Sep 2008, In: Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 28 Aug 2007, In: Biochemistry. 46, 34, p. 9853-64 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells

    Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 134, p. 526-536

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

    Lloyd, M. M., van Reyk, D. M., Davies, Michael J. & Hawkins, Clare Louise, 1 Sep 2008, In: Biochemical Journal. 414, 2, p. 271-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

    Skaff, O., Pattison, D. I. & Davies, Michael J., 15 Aug 2009, In: Biochemical Journal. 422, 1, p. 111-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Hypoxia of human endothelial artery wall cells affects arterial extracellular matrix remodelling and contributes to atherosclerosis development

    Huang, S., Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 563 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  73. Published

    Identification and characterization of protein cross-links induced by oxidative reactions

    Hägglund, Per Mårten, Mariotti, M. & Davies, Michael J., 2018, In: Expert Review of Proteomics. 15, 8, p. 665-681

    Research output: Contribution to journal › Review › Research › peer-review

  74. Published

    Identification and quantification of protein nitration sites in human coronary artery smooth muscle cells in the absence and presence of peroxynitrous acid/peroxynitrite

    Xu, Shuqi, Chuang, Christine, Hawkins, Clare Louise, Hägglund, Per Mårten & Davies, Michael J., 2023, In: Redox Biology. 64, 13 p., 102799.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

    Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 24, UNSP 101226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids

    Trammell, Sam, Gamon, Luke Francis, Gotfryd, K., Michler, Katja Thorøe, Alrehaili, B. D., Rix, I., Knop, Filip Krag, Gourdon, Pontus Emanuel, Lee, Y. K., Davies, Michael J., Gillum, M. P. & Grevengoed, Trisha Jean, 2023, In: Journal of Lipid Research. 64, 9, 9 p., 100361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Identification of galectin-1 and other cellular targets of alpha,beta-unsaturated carbonyl compounds, including dimethylfumarate, by use of click-chemistry probes

    Sauerland, Max Benjamin, Helm, C., Lorentzen, Lasse Gøbel, Manandhar, Asmita, Ulven, Trond, Gamon, Luke Francis & Davies, Michael J., 2023, In: Redox Biology. 59, 15 p., 102560.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines

    Summers, F. A., Morgan, P. E., Davies, Michael J. & Hawkins, Clare Louise, Sep 2008, In: Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]

    Flouda, K., Davies, Michael J. & Hawkins, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.

    Research output: Contribution to journal › Conference abstract in journal › Research

  80. Published

    Implications of differential peroxyl radical-induced inactivation of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase for the pentose phosphate pathway

    Reyes, J. S., Fuentes Lemus, Eduardo, Figueroa, J. D., Rojas, J., Fierro, A., Arenas, F., Hägglund, Per Mårten, Davies, Michael J. & López-Alarcón, C., 2022, In: Scientific Reports. 12, 1, 19 p., 21191.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    In memoriam: Emeritus Professor Robin L. Willson

    Davies, Michael J., Davies, K. J. A., Halliwell, B., Jackson, M. J., Mann, G. E., Poli, G., Radi, R., Riley, P. A., Sies, H., Ward, J. F., Wardman, P. & Willson, J., 2022, In: Free Radical Research. 56, 7-8, p. 572-576 5 p.

    Research output: Contribution to journal › Journal article › Research

  82. Published

    Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides

    Hampton, M. B., Morgan, P. E. & Davies, Michael J., 11 Sep 2002, In: FEBS Letters. 527, 1-3, p. 289-92 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

    Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Jul 2002, In: Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael J., Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates

    Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, Michael J. & Hawkins, Clare Louise, 15 Mar 2012, In: Free Radical Biology & Medicine. 52, 6, p. 1075-85 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

    Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Increasing capacity to deliver diabetes self-management education: Results of the DESMOND lay educator non-randomized controlled equivalence trial

    Carey, M. E., Mandalia, P. K., Daly, H., Gray, L. J., Hale, R., Martin Stacey, L., Taub, N., Skinner, Timothy, Stone, M., Heller, S., Khunti, K. & Davies, Michael J., 1 Jan 2014, In: Diabetic Medicine. 31, 11, p. 1431-1438 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Induction of DNA damage by oxidised amino acids and proteins

    Luxford, C., Dean, R. T. & Davies, Michael J., 2002, In: Biogerontology. 3, 1-2, p. 95-102 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Influence of O-2 on riboflavin-mediated photo-oxidation of lysozyme: [Meeting Abstract]

    Silva, E., Tirapegui, C., Fuentes-Lemus, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Caroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S58-S59 P-46.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  90. Published

    Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage

    Xu, Shuqi, Chuang, Christine, Malle, E., Gamon, Luke Francis, Hawkins, Clare Louise & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 188, p. 162-174

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone

    Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael J., 2020, In: Redox Biology. 28, 9 p., 101335 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides

    Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack

    Morgan, P. E., Dean, R. T. & Davies, Michael J., Apr 2002, In: European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis

    Moheimani, F., Kim, C. H. J., Rahmanto, A. S., van Reyk, D. M. & Davies, Michael J., Jul 2012, In: Atherosclerosis. 223, 1, p. 144-51 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides

    Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, Clare Louise & Davies, Michael J., May 2014, In: Free Radical Biology & Medicine. 70, p. 96-105 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides

    Rees, M. D., Bottle, S. E., Fairfull-Smith, K. E., Malle, E., Whitelock, J. M. & Davies, Michael J., 1 Jul 2009, In: Biochemical Journal. 421, 1, p. 79-86 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products

    Gracanin, M. & Davies, Michael J., 15 May 2007, In: Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Interaction kinetics of selenium -containing compounds with oxidants

    Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael J., 2020, In: Free Radical Biology and Medicine. 155, p. 58-68

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins: [Meeting Abstract]

    Ignasiak-Kciuk, M., Shashikadze, B., Frackowiak, K., Gamon, Luke Francis, Davies, Michael J. & Marciniak, B., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S30-S30 89.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  100. Published

    Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]

    Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.

    Research output: Contribution to journal › Conference abstract in journal › Research

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