Michael Givskov

Michael Givskov

Professor

Member of:

    ORCID: 0000-0001-5004-8609

    Publication year:
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    1 - 25 out of 336Page size: 25
    1. 2024
    2. Published

      Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump

      Kristensen, Rasmus, Andersen, Jens Bo, Rybtke, Morten Levin, Jansen, C. U., Fritz, Blaine Gabriel, Kiilerich, R. O., Uhd, J., Bjarnsholt, Thomas, Qvortrup, K., Tolker-Nielsen, Tim, Givskov, Michael & Jakobsen, Tim Holm, 2024, In: Antimicrobial Agents and Chemotherapy. 68, 2

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture

      Eilers, K., Hoong Yam, J. K., Liu, X., Goh, Y. F., To, K. N., Paracuellos, P., Morton, R., Brizuela, J., Hui Yong, A. M., Givskov, Michael, Freibert, S. A., Bange, G., Rice, S. A., Steinchen, W. & Filloux, A., 2024, In: Journal of Biological Chemistry. 300, 2, 105659.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. 2023
    5. Published

      Auranofin inhibits virulence pathways in Pseudomonas aeruginosa

      Yam, J. K. H., Tan, L. Z. W., Hong, Z., Salido, M. M. S., Woo, B. Y., Yong, A. M. H., Tan, C. A. Z., Li, S. F. Y., Yang, L., Givskov, Michael & Chng, S. S., 2023, In: Bioorganic and Medicinal Chemistry. 79, 117167.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      A genetic switch controls Pseudomonas aeruginosa surface colonization

      Manner, C., Dias Teixeira, R., Saha, D., Kaczmarczyk, A., Zemp, R., Wyss, F., Jaeger, T., Laventie, B. J., Boyer, S., Malone, J. G., Qvortrup, K., Andersen, Jens Bo, Givskov, Michael, Tolker-Nielsen, Tim, Hiller, S., Drescher, K. & Jenal, U., 2023, In: Nature Microbiology. 8, p. 1520–1533

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Associational Resistance to Predation by Protists in a Mixed Species Biofilm

      Goh, Y. F., Røder, Henriette Lyng, Chan, S. H., Ismail, M. H., Madsen, Jonas Stenløkke, Lee, K. W. K., Sørensen, Søren Johannes, Givskov, Michael, Burmølle, Mette, Rice, S. A. & McDougald, D., 2023, In: Applied and Environmental Microbiology. 89, 2, 16 p., e0174122.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Characterization of TelE, a T7SS LXG Effector Exhibiting a Conserved C-Terminal Glycine Zipper Motif Required for Toxicity

      Teh, W. K., Ding, Y., Gubellini, F., Filloux, A., Poyart, C., Givskov, Michael & Dramsi, S., 2023, In: Microbiology Spectrum. 11, 4, e0148123.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 2022
    10. Published

      A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

      Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Adaptation to an Amoeba Host Leads to Pseudomonas aeruginosa Isolates with Attenuated Virulence

      Leong, W., Poh, W. H., Williams, J., Lutz, C., Mozammel Hoque, M., Poh, Y. H., Yee, B. Y. K., Chua, C., Givskov, Michael, Sanderson-Smith, M., Rice, S. A. & McDougald, D., 2022, In: Applied and Environmental Microbiology. 88, 5, e02322.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo

      Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, Morten Levin, Seliktar, D., Kofidis, T., Høiby, Niels, Tolker-Nielsen, Tim, Song, Z. & Givskov, Michael, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa

      Yam, J. K. H., Aung, T. T., Chua, S. L., Cheng, Y., Kohli, G. S., Zhou, J., Constancias, F., Liu, Y., Cai, Z., Salido, M. M. S., Drautz-Moses, D. I., Rice, S. A., Schuster, S. C., Boo, Z. Z., Wu, B., Kjelleberg, S., Tolker-Nielsen, T., Lakshminarayanan, R., Beuerman, R. W., Yang, L. & 1 others, Givskov, Michael, 2022, In: Infection and Immunity. 90, 8

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Phenotypic and integrated analysis of a comprehensive Pseudomonas aeruginosa PAO1 library of mutants lacking cyclic-di-GMP-related genes

      Eilers, K., Kuok Hoong Yam, J., Morton, R., Mei Hui Yong, A., Brizuela, J., Hadjicharalambous, C., Liu, X., Givskov, Michael, Rice, S. A. & Filloux, A., 2022, In: Frontiers in Microbiology. 13, 949597.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors

      Flagstad, T., Pedersen, M. T., Jakobsen, Tim Holm, Felding, J., Tolker-Nielsen, Tim, Givskov, Michael, Qvortrup, K. & Nielsen, Thomas Eiland, 2022, In: Bioorganic and Medicinal Chemistry Letters. 57, 128499.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. 2021
    17. Published

      Bacterial genotoxins induce T cell senescence

      Mathiasen, S. L., Gall Mas, Laura, Pateras, I. S., Theodorou, S. D. P., Namini, Martin Rich Javadi, Hansen, Morten Bagge, Martin, O. C. B., Vadivel, Chella Krishna, Ntostoglou, K., Butter, D., Givskov, Michael, Geisler, Carsten, Akbar, A. N., Gorgoulis, V. G., Frisan, T., Ødum, Niels & Krejsgaard, T., 2021, In: Cell Reports. 35, 10, 109220.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Carbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutants

      Nair, H. A. S., Subramoni, S., Poh, W. H., Hasnuddin, N. T. B., Tay, M., Givskov, Michael, Tolker-Nielsen, Tim, Kjelleberg, S., McDougald, D. & Rice, S. A., 2021, In: BMC Microbiology. 21, 10 p., 255.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through loss of the Rieske cytochrome bc1 sub-unit

      Soh, E., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Camara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, bioRxiv, 43 p.

      Research output: Working paper › Preprint › Research

    20. Published

      Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through lack of the Rieske cytochrome bc1sub-unit

      Soh, E. Y. C., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Cámara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, In: PLOS Pathogens. 17, 8, 25 p., e1009425.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms

      Andersen, Jens Bo, Hultqvist, Louise Dahl, Jansen, C. U., Jakobsen, Tim Holm, Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Uhd, J., Fritz, Blaine Gabriel, Seifert, R., Berthelsen, J., Nielsen, Thomas Eiland, Qvortrup, K., Givskov, Michael & Tolker-Nielsen, Tim, 2021, In: npj Biofilms and Microbiomes. 7, 13 p., 59.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Induction of native c-di-GMP phosphodiesterases leads to dispersal of Pseudomonas aeruginosa biofilms

      Andersen, Jens Bo, Kragh, K. N., Hultqvist, Louise Dahl, Rybtke, Morten Levin, Nilsson, Carl Martin Peter, Jakobsen, Tim Holm, Givskov, Michael & Tolker-Nielsen, Tim, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 4, e02431-20.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Periodontitis associates with species-specific gene expression of the oral microbiota

      Midjord-Belstrøm, Daniel, Constancias, F., Drautz-Moses, D. I., Schuster, S. C., Veleba, M., Mahé, F. & Givskov, Michael, 2021, In: npj Biofilms and Microbiomes. 7, 76.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      SAR study of 4-arylazo-3,5-diamino-1: H -pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms

      Jansen, C. U., Uhd, J., Andersen, Jens Bo, Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Nilsson, Carl Martin Peter, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Qvortrup, K. M., 2021, In: RSC Medicinal Chemistry. 12, 11, p. 1868-1878 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Transcriptional Activity of Predominant Streptococcus Species at Multiple Oral Sites Associate With Periodontal Status

      Midjord-Belstrøm, Daniel, Constancias, F., Markvart, Merete, Sikora, Martin, Sørensen, Christiane Elisabeth & Givskov, Michael, 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 13 p., 752664.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. 2020
    27. Published

      Pseudomonas aeruginosa isolates co-incubated with Acanthamoeba castellanii exhibit phenotypes similar to chronic cystic fibrosis isolates

      Leong, W., Lutz, C., Williams, J., Poh, Y. H., Ken Yee, B. Y., Chua, C., Rice, S. A., Givskov, Michael, Sanderson-Smith, M. & McDougald, D., 2020, bioRxiv, 49 p.

      Research output: Working paper › Preprint › Research

    28. Published

      A mouse ear skin model to study the dynamics of innate immune responses against Staphylococcus aureus biofilms

      Abdul Hamid, A. I., Nakusi, L., Givskov, Michael, Chang, Y. T., Marquès, C. & Gueirard, P., 2020, In: BMC Microbiology. 20, 1, 12 p., 22.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

      Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. 2019
    31. Published

      Antibiotics inhibit tumor and disease activity in cutaneous T cell lymphoma

      Lindahl, L. M., Willerslev-Olsen, A., Gjerdrum, L. M. R., Nielsen, P. R., Blümel, E., Rittig, A. H., Celis, P., Herpers, B., Becker, J. C., Stausbøl-Grøn, B., Wasik, M. A., Gluud, M., Fredholm, S., Buus, T. B., Johansen, C., Nastasi, C., Peiffer, L., Kubat, L., Bzorek, M., Eriksen, J. O. & 11 others, Krejsgaard, T., Bonefeld, Charlotte Menne, Geisler, Carsten, Mustelin, T., Langhoff, E., Givskov, Michael, Woetmann, Anders , Kilian, M., Litman, Thomas, Iversen, L. & Ødum, Niels, 26 Sep 2019, In: Blood. 134, 13, p. 1072-1083

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 5838523