Michael Gajhede
Professor
Structural Biology
Universitetsparken 2
2100 København Ø
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A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase
Henriksen, A., Aghajari, N., Jensen, K. F. & Gajhede, Michael, 1996, In: Biochemistry. 35, 12, p. 3803-3809Research output: Contribution to journal › Journal article › Research › peer-review
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A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils
Vestergaard, Bente, Jensen, M. G., Roessle, M., Kastrup, Jette Sandholm Jensen, van de Weert, Marco, Flink, J. M., Frøkjær, Sven, Gajhede, Michael & Svergun, D. I., 2007, In: PLoS - Biology. 5, 5, p. 1089-1097Research output: Contribution to journal › Journal article › Research › peer-review
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A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage
Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322Research output: Contribution to journal › Journal article › Research › peer-review
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A tetrazolyl-substituted subtype-selective AMPA receptor agonist
Vogensen, S. B., Frydenvang, Karla Andrea, Greenwood, J. R., Postorino, G., Nielsen, Birgitte, Pickering, Darryl S, Ebert, B., Bølcho, U., Egebjerg, J., Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Johansen, Tommy Nørskov, Clausen, Rasmus Prætorius & Krogsgaard-Larsen, Povl, 2007, In: Journal of Medicinal Chemistry. 50, 10, p. 2408-2414Research output: Contribution to journal › Journal article › Research › peer-review
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A unique set of SH3-SH3 interactions controls IB1 homodimerization
Kristensen, O., Guenat, S., Dar, I., Allaman-Pillet, N., Abderrahmani, A., Ferdaoussi, M., Roduit, R., Maurer, F., Beckmann, J. S., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Bonny, C., 2006, In: E M B O Journal. 25, 4, p. 785-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity
Shahsavar, A., Ahring, P. K., Olsen, J. A., Krintel, C., Kastrup, Jette Sandholm Jensen, Balle, T. & Gajhede, Michael, Oct 2015, In: Molecular Pharmacology. 88, 4, p. 697-707 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family
Skov, L. K., Mirza, Osman Asghar, Henriksen, A., De Montalk, G. P., Remaud-Simeon, M., Sarçabal, P., Willemot, R. M., Monsan, P. & Gajhede, Michael, 6 Jul 2001, In: Journal of Biological Chemistry. 276, 27, p. 25273-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification.
Ostergaard, L., Teilum, Kaare, Mirza, Osman Asghar, Mattsson, O., Petersen, M., Welinder, K. G., Mundy, J., Gajhede, Michael & Henriksen, A., 2000, In: Plant Molecular Biology. 44, 2, p. 231-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Arabidopsis thaliana peroxidase N: structure of a novel neutral peroxidase
Mirza, Osman Asghar, Henriksen, A., Ostergaard, L., Welinder, K. G. & Gajhede, Michael, Mar 2000, In: Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 3, p. 372-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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At være eller ikke være en antagonist
Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2009, In: Lægemiddelforskning. p. 43-45Research output: Contribution to journal › Journal article › Communication
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Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2
Krintel, C., Dorosz, J., Larsen, A. H., Thorsen, T. S., Venskutonytė, R., Mirza, Osman Asghar, Gajhede, Michael, Boesen, T. & Kastrup, Jette Sandholm Jensen, 2021, In: The FEBS Journal. 288, p. 995-1007 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate
Venskutonyte, R., Frydenvang, Karla Andrea, Gajhede, Michael, Bunch, Lennart, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, Dec 2011, In: Journal of Structural Biology. 176, 3, p. 307-314Research output: Contribution to journal › Journal article › Research › peer-review
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Chaperone binding at the ribosomal exit tunnel
Kristensen, O. & Gajhede, Michael, 2003, In: Structure. 11, 12, p. 1547-56 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical and thermal unfolding of calreticulin
Duus, K., Larsen, N., Tran, T. A. T., Güven, E., Skov, L. K., Jespersgaard, C., Gajhede, Michael & Houen, G., 2013, In: Protein and Peptide Letters. 20, p. 562-568Research output: Contribution to journal › Journal article › Research › peer-review
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Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters
Assaf, Z., Larsen, A. P., Venskutonyte, R., Han, L., Abrahamsen, B., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Jensen, Anders A., Pickering, Darryl S, Frydenvang, Karla Andrea, Gefflaut, T. & Bunch, Lennart, 2013, In: Journal of Medicinal Chemistry. 56, 4, p. 1614-1628Research output: Contribution to journal › Journal article › Research › peer-review
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Cobalt(III) Cage Complexes Linked to 4-Pyridyl: Models for Protein Modification
Gajhede, Michael, Hammershøi, Anders & Skov, L. K., 1991, In: Dalton Transactions (Print Edition). 45, 5, p. 474-481 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformational stability of calreticulin
Jørgensen, C. S., Trandum, C., Larsen, N. B., Ryder, L. R., Gajhede, Michael, Skov, L., Højrup, P., Barkholt, V. & Houen, G., 2005, In: Protein and Peptide Letters. 12, 7, p. 687-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Corrigendum to "Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate" [J. Struct. Biol. 176 (2011) 307-314]
Venskutonyte, R., Frydenvang, Karla Andrea, Gajhede, Michael, Bunch, Lennart, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, Nov 2013, In: Journal of Structural Biology. 184, 2, p. 381 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHßE Suggests a Unique Mode of Antagonism
Shahsavar, Azadeh, Kastrup, Jette Sandholm Jensen, Nielsen, E. Ø., Kristensen, Jesper Langgaard, Gajhede, Michael & Balle, T., 2012, In: P L o S One. 7, 8, p. e40757Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal Structure of NCAM2 Ig1 (I4122 Cell Unit)
Kulahin, N., Rasmussen, K. K., Kristensen, O., Kastrup, Jette Sandholm Jensen, Poulsen, Jens-Christian Navarro, Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008Research output: Non-textual form › Dataset › Research
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Crystal Structure of NCAM2 Ig1-2
Kulahin, N., Rasmussen, K. K., Kristensen, O., Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008Research output: Non-textual form › Dataset › Research
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Crystal Structure of NCAM2 Ig2-3
Kulahin, N., Rasmussen, K. K., Kristensen, O., Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008Research output: Non-textual form › Dataset › Research
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Crystal Structure of NCAM2 Ig34
Kulahin, N., Rasmussen, K. K., Kristensen, O., Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008Research output: Non-textual form › Dataset › Research
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Crystal Structures of Amylosucrase from Neisseria polysaccharea in Complex with D-Glucose and the Active Site Mutant Glu328Gln in Complex with the Natural Substrate Sucrose
Mirza, O., Skov, L. K., Remaud-Simeon, M., Potocki de Montalk, G., Albenne, C., Monsan, P. & Gajhede, Michael, 2001, In: Biochemistry. 40, p. 9032-9039Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site
Kvist, T., Steffensen, T. B., Greenwood, J. R., Mehrzad Tabrizi, F., Hansen, K. B., Gajhede, Michael, Pickering, Darryl S, Traynelis, S. F., Kastrup, Jette Sandholm Jensen & Bräuner, Hans, 2013, In: The Journal of Biological Chemistry. 288, p. 33124-35 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1304192
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Structure of rat acidic fibroblast growth factor at 1.4 A resolution.
Research output: Contribution to journal › Journal article › Research › peer-review
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