Michael Gajhede
Professor
Structural Biology
Universitetsparken 2
2100 København Ø
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Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule
Kulahin, N., Kristensen, O., Rasmussen, K. K., Olsen, L., Rydberg, P., Vestergaard, Bente, Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E., Walmod, P. S. & Gajhede, Michael, 9 Feb 2011, In: Structure. 19, 2, p. 203-211Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal Structure of NCAM2 Ig34
Kulahin, N., Rasmussen, K. K., Kristensen, O., Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008Research output: Non-textual form › Dataset › Research
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Chaperone binding at the ribosomal exit tunnel
Kristensen, O. & Gajhede, Michael, 2003, In: Structure. 11, 12, p. 1547-56 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystallization of a stringent response factor from Aquifex aeolicus
Kristensen, O., Laurberg, M. & Gajhede, Michael, 2002, In: Acta Crystallographica. Section D: Biological Crystallography. 58, Pt 7, p. 1198-200 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp
Kristensen, O., Ross, B. & Gajhede, Michael, 2008, In: Journal of Molecular Biology. 375, 5, p. 1469-1476Research output: Contribution to journal › Journal article › Research › peer-review
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A unique set of SH3-SH3 interactions controls IB1 homodimerization
Kristensen, O., Guenat, S., Dar, I., Allaman-Pillet, N., Abderrahmani, A., Ferdaoussi, M., Roduit, R., Maurer, F., Beckmann, J. S., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Bonny, C., 2006, In: E M B O Journal. 25, 4, p. 785-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family
Kristensen, O., Laurberg, M., Liljas, A., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2004, In: Biochemistry. 43, 28, p. 8894-900 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor
Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, P., Kastrup, Jette Sandholm Jensen, Helin, K., Olsen, L. & Gajhede, Michael, Jun 2012, In: F E B S Journal. 279, 11, p. 1905-1914Research output: Contribution to journal › Journal article › Research › peer-review
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Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases
Kristensen, J. B. L., Nielsen, A. L., Jørgensen, L., Kristensen, L. H., Helgstrand, C., Juknaite, L., Kristensen, Jesper Langgaard, Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius, Olsen, L. & Gajhede, Michael, 23 Jun 2011, In: F E B S Letters. 585, 12, p. 1951-1956Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors
Kristensen, Anders Skov, Hansen, K. B., Naur, P., Olsen, L., Kurtkaya, N. L., Dravid, S. M., Kvist, T., Yi, F., Pøhlsgaard, J., Clausen, Rasmus Prætorius, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Traynelis, S. F., Feb 2016, In: Molecular Pharmacology. 89, 2, p. 253-262 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain
Krintel, C., Frydenvang, Karla Andrea, Ceravalls de Rabassa, A., Kaern, A. M., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 27 Mar 2014, In: F E B S Journal. p. 2422–2430 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2
Krintel, C., Dorosz, J., Larsen, A. H., Thorsen, T. S., Venskutonytė, R., Mirza, Osman Asghar, Gajhede, Michael, Boesen, T. & Kastrup, Jette Sandholm Jensen, 2021, In: The FEBS Journal. 288, p. 995-1007 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain
Krintel, C., Harpsøe, Kasper, Zachariassen, L. G., Peters, D., Frydenvang, Karla Andrea, Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2013, In: Acta Crystallographica Section D: Structural Biology. 69, Pt 9, p. 1645-1652 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2
Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In: Biochemical Journal. 441, 1, p. 173-178Research output: Contribution to journal › Journal article › Research › peer-review
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Realizing integration in structural biology: The 2022 ISBUC Annual Meeting
Kragelund, Birthe Brandt, Loland, Claus Juul, Montoya, Guillermo, Hatzakis, Nikos, Martinez, Karen Laurence, Gajhede, Michael, Christensen, Caspar Elo & Holt, Lucy, 2023, In: Structure. 31, 7, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism
Kobberø, S. D., Gajhede, Michael, Mirza, Osman Asghar, Kløverpris, S., Kjær, T. R., Mikkelsen, J. H., Boesen, T. & Oxvig, C., 2022, In: Nature Communications. 13, 1, 16 p., 6084.Research output: Contribution to journal › Journal article › Research › peer-review
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The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209
Kasper, C., Pickering, Darryl S, Mirza, Osman Asghar, Olsen, L., Kristensen, Anders Skov, Greenwood, J. R., Liljefors, T., Schousboe, Arne, Wätjen, F., Gajhede, Michael, Sigurskjold, B. W. & Kastrup, Jette Sandholm Jensen, 2006, In: Journal of Molecular Biology. 357, 4, p. 1184-201 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4
Kasper, C., Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2008, In: FEBS Letters. 582, 29, p. 4089-4094Research output: Contribution to journal › Journal article › Research › peer-review
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Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites
Kaae, B. H., Harpsøe, Kasper, Kastrup, Jette Sandholm Jensen, Sanz, A. C., Pickering, Darryl S, Metzler, B., Clausen, Rasmus Prætorius, Gajhede, Michael, Sauerberg, P., Liljefors, T. & Madsen, Ulf, 2007, In: Chemistry & Biology. 14, 11, p. 1294-303 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cyclic Acetals. Structural Analysis of 1,3‐Dioxepine and Related Compounds
Jørgensen, Flemming Steen, Gajhede, Michael & Frei, B., 1 Jan 1985, In: Helvetica Chimica Acta. 68, 8, p. 2148-2157 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformational stability of calreticulin
Jørgensen, C. S., Trandum, C., Larsen, N. B., Ryder, L. R., Gajhede, Michael, Skov, L., Højrup, P., Barkholt, V. & Houen, G., 2005, In: Protein and Peptide Letters. 12, 7, p. 687-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution
Jørgensen, A. D., Nøhr, J., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Sigurskjold, B. W., Sauer, J., Svergun, D. I., Svensson, B. & Vestergaard, Bente, 2008, In: Journal of Biological Chemistry. 283, 21, p. 14772-14780Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors
Juknaite, L., Venskutonyte, R., Assaf, Z., Faure, S., Gefflaut, T., Aitken, D. J., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Bunch, Lennart, Frydenvang, Karla Andrea & Pickering, Darryl S, 2012, In: Journal of Structural Biology. 180, 1, p. 39-46Research output: Contribution to journal › Journal article › Research › peer-review
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Peptides Derived from Histone 3 and Modified at Position 18 Inhibit Histone Demethylase KDM6 Enzymes
Jones, S. E., Olsen, L., Dorosz, J., Seger, S. T., Andersson, J. L., Kristensen, L. H. & Gajhede, Michael, 4 Sep 2018, In: ChemBioChem. 19, 17, p. 1817-1822Research output: Contribution to journal › Letter › Research › peer-review
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Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity
Jones, S. E., Olsen, L. & Gajhede, Michael, 2018, In: Biochemistry. 57, 5, p. 585–592Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1304192
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Structure of rat acidic fibroblast growth factor at 1.4 A resolution.
Research output: Contribution to journal › Journal article › Research › peer-review
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