Michael Gajhede
Professor
Structural Biology
Universitetsparken 2
2100 København Ø
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Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH
Aduri, N. G., Montefiori, M., Khalil, R., Gajhede, Michael, Jørgensen, Flemming Steen & Mirza, Osman Asghar, 31 Jan 2019, In: ACS Omega. 4, 1, p. 2040-2046 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular architecture of the Jumonji C family histone demethylase KDM5B
Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular basis of allergic cross-reactivity between group 1 major allergens from birch and apple
Holm, J., Bærentzen, G., Gajhede, Michael, Ipsen, H., Larsen, J. N., Løwenstein, H., Wissenbach, M. & Spangfort, M. D., 2001, In: Journal of Chromatography - B. 756, 1-2, p. 307-313 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular basis of the amylose-like polymer formation catalyzed by Neisseria polysaccharea amylosucrase
Albenne, C., Skov, L., Mirza, Osman Asghar, Gajhede, Michael, Feller, G., D'Amico, S., André, G., Potocki-Véronèse, G., van der Veen, B. A., Monsan, P. & Remaud-Simeon, M., 2 Jan 2004, In: Journal of Biological Chemistry. 279, 1, p. 726-34 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors
Harpsøe, Kasper, Hald, H., Timmermann, D. B., Jensen, M. L., Dyhring, T., Nielsen, E. Ø., Peters, D., Balle, T., Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Ahring, P. K., 25 Jan 2013, In: Journal of Biological Chemistry. 288, 4, p. 2559-2570 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4
Kasper, C., Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2008, In: FEBS Letters. 582, 29, p. 4089-4094Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors
Olsen, J. A., Balle, T., Gajhede, Michael, Ahring, P. K. & Kastrup, Jette Sandholm Jensen, 17 Mar 2014, In: PLOS ONE. 9, 3, p. e91232 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand-binding domain
Venskutonyte, R., Larsen, A. P., Frydenvang, Karla Andrea, Gajhede, Michael, Gefflaut, T., Pickering, Darryl S, Bunch, Lennart & Kastrup, Jette Sandholm Jensen, 2014, In: ChemMedChem. 9, 10, p. 2254-2259 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor
Owczarek, S., Kiryushko, D., Hald Larsen, M., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Sandi, C., Berezin, V., Bock, E. & Soroka, V., 2010, In: The FASEB Journal. 24, 4, p. 1139-1150 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity
Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., Dar, I., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 6 Dec 2002, In: Journal of Biological Chemistry. 277, 49, p. 47741-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus
Wang, X., Hald, H., Ernst, H. A., Egebjerg, J., Christensen, K. V., Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Mirza, Osman Asghar, 2010, In: Protein Expression and Purification. 71, 2, p. 179-183Research output: Contribution to journal › Journal article › Research › peer-review
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Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid
Hald, H., Naur, P., Pickering, Darryl S, Sprogøe, D., Madsen, Ulf, Timmermann, D. B., Ahring, P. K., Liljefors, T., Schousboe, Arne, Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2007, In: Journal of Biological Chemistry. 282, 35, p. 25726-25736Research output: Contribution to journal › Journal article › Research › peer-review
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Peptides Derived from Histone 3 and Modified at Position 18 Inhibit Histone Demethylase KDM6 Enzymes
Jones, S. E., Olsen, L., Dorosz, J., Seger, S. T., Andersson, J. L., Kristensen, L. H. & Gajhede, Michael, 4 Sep 2018, In: ChemBioChem. 19, 17, p. 1817-1822Research output: Contribution to journal › Letter › Research › peer-review
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Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors
Juknaite, L., Venskutonyte, R., Assaf, Z., Faure, S., Gefflaut, T., Aitken, D. J., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Bunch, Lennart, Frydenvang, Karla Andrea & Pickering, Darryl S, 2012, In: Journal of Structural Biology. 180, 1, p. 39-46Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors
Kristensen, Anders Skov, Hansen, K. B., Naur, P., Olsen, L., Kurtkaya, N. L., Dravid, S. M., Kvist, T., Yi, F., Pøhlsgaard, J., Clausen, Rasmus Prætorius, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Traynelis, S. F., Feb 2016, In: Molecular Pharmacology. 89, 2, p. 253-262 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plant peroxidases: Substrate complexes with mechanistic implications
Gajhede, Michael, 2001, In: Biochemical Society Transactions. 29, p. 91-99Research output: Contribution to journal › Journal article › Research
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Rational and combinatorial engineering of the glucan synthesizing enzyme amylosucrase
Albenne, C., Van Der Veen, B. A., Potocki-Véronèse, G., Joucla, G., Skov, L., Mirza, Osman Asghar, Gajhede, Michael, Monsan, P. & Remaud-Simeon, M., 1 Aug 2003, In: Biocatalysis and Biotransformation. 21, 4-5, p. 271-277 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Realizing integration in structural biology: The 2022 ISBUC Annual Meeting
Kragelund, Birthe Brandt, Loland, Claus Juul, Montoya, Guillermo, Hatzakis, Nikos, Martinez, Karen Laurence, Gajhede, Michael, Christensen, Caspar Elo & Holt, Lucy, 2023, In: Structure. 31, 7, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
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Reversal of ABCG2/BCRP-mediated multidrug resistance by 5,3’,5’-trihydroxy-3,6,7,4’-tetramethoxyflavone isolated from the Australian desert plant Eremophila galeata Chinnock
Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth Thermann, Stenvang, Jan & Stærk, Dan, 2021, In: Biomolecules. 11, 10, 19 p., 1534.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of CD3 gamma in T cell receptor assembly
Dietrich, J., Neisig, A., Hou, X., Wegener, A. M., Gajhede, Michael & Geisler, Carsten, 1996, In: Journal of Cell Biology. 132, 3, p. 299-310 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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STRUCTURE OF 1-DIMETHYLAMINO-2,2,3,4,4-PENTAMETHYL-1-LAMBDA-5-PHOSPHETANE 1-SULFIDE, C10H22NPS, AT 105 K
Gajhede, Michael, DAHL, O. & Nielsen, J., 1985, In: Acta Crystallographica. Section C: Crystal Structure Communications. 41, JUN, p. 935-937Research output: Contribution to journal › Journal article › Research › peer-review
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Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR
Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, Michael, Hansen, Paul Robert & Mirza, Osman Asghar, 16 Feb 2017, In: Research in Microbiology. 168, 5, p. 443-449Research output: Contribution to journal › Journal article › Research › peer-review
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Site-directed mutagenesis of key amino acids in the active site of amylosucrase from Neisseria polysaccharea
Albenne, C., Potocki De Montalk, G., Monsan, P., Skov, L., Mirza, Osman Asghar, Gajhede, Michael & Remaud-Simeon, M., 1 Dec 2002, In: Biologia - Section Cellular and Molecular Biology. 57, SUPPL. 11, p. 119-128 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution
Jørgensen, A. D., Nøhr, J., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Sigurskjold, B. W., Sauer, J., Svergun, D. I., Svensson, B. & Vestergaard, Bente, 2008, In: Journal of Biological Chemistry. 283, 21, p. 14772-14780Research output: Contribution to journal › Journal article › Research › peer-review
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Small-molecule modulators of tumor necrosis factor signaling
Chédotal, H., Narayanan, Dilip, Povlsen, K., Gotfredsen, C. H., Brambilla, R., Gajhede, Michael, Bach, Anders & Clausen, M. H., 2023, In: Drug Discovery Today. 28, 6, 103575.Research output: Contribution to journal › Review › Research › peer-review
ID: 1304192
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Structure of rat acidic fibroblast growth factor at 1.4 A resolution.
Research output: Contribution to journal › Journal article › Research › peer-review
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