Mette Kolpen

Mette Kolpen

Guest researcher


Publication year:
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1 - 38 out of 38Page size: 50
  1. 2024
  2. E-pub ahead of print

    Bacterial aerobic respiration is a major consumer of oxygen in sputum from patients with acute lower respiratory tract infection

    Jensen, Peter Østrup, Olsen, P., Dungu, A. M., Egelund, G. B., Jensen, A. V., Ravn, P., Lindegaard, Birgitte, Hertz, Frederik Boëtius, Bjarnsholt, Thomas, Faurholt-Jepsen, D. & Kolpen, Mette, 2024, (E-pub ahead of print) In: APMIS.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes

    Bové, M., Kolpen, Mette, Lichtenberg, Mads, Bjarnsholt, Thomas & Coenye, T., 2023, In: Microbiology (United Kingdom). 169, 1, 001278.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination

    Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup, Pressler, T., Johansen, Helle Krogh & Kolpen, Mette, 2023, In: APMIS. 131, 8, p. 419-425

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Exhaled nitric oxide in intubated ICU patients on mechanical ventilation—a feasibility study

    Kofoed, A., Hindborg, M., Hjembæk-Brandt, J., Sørensen, C. D., Kolpen, Mette & Bestle, Morten Heiberg, 2023, In: Journal of Breath Research. 17, 4, 6 p., 046014.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Hyperbaric oxygen therapy augments ciprofloxacin effect against Pseudomonas aeruginosa biofilm infected chronic wounds in a mouse model

    Laulund, A. S., Schwartz, F. A., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Calum, Henrik Pierre, Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 5, 100100.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2022
  9. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, Mette, Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, P., Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: European Respiratory Journal. Supplement. 60, Suppl. 66, 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections

    Jensen, Peter Østrup, Møller, S. A., Stjernekilde, S., Olsen, P., Moser, Claus Ernst, Schwartz, F. A., Lerche, C. J., Høiby, Niels, Hyldegaard, Ole, Faurholt-jepsen, D. & Kolpen, Mette, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 201-223 (Antibiofilm Strategies, Vol. 11).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  11. Published

    Increased sputum lactate during oral glucose tolerance test in cystic fibrosis

    Jensen, Peter Østrup, Nielsen, B. U., Kolpen, Mette, Pressler, T., Faurholt-Jepsen, D. & Mathiesen, I. H. M., 2022, In: APMIS. 130, 8, p. 535-539

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Synergy between Mecillinam and Ceftazidime/Avibactam or Avibactam against Multi-Drug-Resistant Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae

    List, K. K., Kolpen, Mette, Kragh, K. N., Charbon, Godefroid, Radmer, S., Hansen, F., Løbner-Olesen, Anders, Frimodt-Møller, N. & Hertz, F. B., 2022, In: Antibiotics. 11, 10, 13 p., 1280.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment

    Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2021
  15. Published

    Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa

    Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2019
  19. Published

    Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

    Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

    Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Oxygen restriction generates difficult-to-culture p. Aeruginosa

    Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The inflamed sputum in lower respiratory tract infection: l-lactate levels are correlated to neutrophil accumulation

    Fredman, G., Kolpen, Mette, Hertz, F. B., Petersen, P. T., Jensen, A. V., Baunbæk-Egelund, G., Ravn, Pernille, Jensen, Peter Østrup & Faurholt-Jepsen, Daniel, 2019, In: APMIS. 127, 2, p. 72-79

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2018
  24. Published

    Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms

    Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model

    Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas & Kühl, Michael, 2018, In: npj Biofilms and Microbiomes. 4, 11 p., 3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2017
  27. Published

    Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin

    Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Biofilms and host response - helpful or harmful

    Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Diagnosis of biofilm infections in cystic fibrosis patients

    Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis

    Lerche, C. J., Christophersen, L. J., Kolpen, Mette, Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, Ole, Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Microenvironmental characteristics and physiology of biofilms in chronic infections of CF patients are strongly affected by the host immune response

    Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N. & Kühl, Michael, 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 276–288 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    The consequences of being in an infectious biofilm – microenvironmental conditions governing antibiotic tolerance

    Sønderholm, M., Bjarnsholt, Thomas, Alhede, M., Kolpen, Mette, Jensen, Peter Østrup, Kühl, Michael & Kragh, K. N., 2017, In: International Journal of Molecular Sciences. 18, 12, 14 p., 2688.

    Research output: Contribution to journal › Review › Research › peer-review

  33. 2016
  34. Published

    Diffusion retardation by binding of tobramycin in an alginate biofilm model

    Cao, B., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus Ernst & Sams, T., 21 Apr 2016, In: P L o S One. 11, 4, 11 p., e0153616.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

    Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

    Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  37. 2015
  38. Published

    RE-SENSITIZATION OF ANOXIC PSEUDOMONAS AERUGINOSA BIOFILMS WITH RE-OXYGENATION USING HYPERBARIC OXYGEN TREATMENT

    Kolpen, Mette, Mousavi, N., Sams, T., Kragh, K. N., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, P. O., Oct 2015, In: Pediatric Pulmonology. 50, S41, p. 312-312 1 p., 322.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  39. Published

    Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum

    Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas, Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N., Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2015, In: International Journal of Medical Microbiology. 305, 1, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2014
  41. Published

    Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

    Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

    Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen

    Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

    Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

    Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. 2013
  47. Published

    Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

    Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, Høiby, Niels & Bjarnsholt, Thomas, 2013, In: P L o S One. 8, 7, 17 p., e68484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. 2011
  49. Published

    Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

    Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  50. 2010
  51. Published

    Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

    Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection

    Kolpen, Mette, Bjarnsholt, Thomas, Moser, C., Hansen, C. R., Kühl, Michael, Høiby, Niels & Jensen, P. Ø., 2010, In: Journal of Cystic Fibrosis. Supplement 1, p. S49 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

ID: 17579642