Merete Fredholm

Merete Fredholm

Professor


Publication year:
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1 - 100 out of 285Page size: 100
  1. 2024
  2. Published

    Association of serum and fecal microRNA profiles in healthy cats and cats with gastrointestinal cancer or chronic inflammatory enteropathy

    Lyngby, Janne Graarup, Brogaard, L., Kristensen, Annemarie T., Fredholm, Merete, Bjørnvad, Charlotte Reinhard, Salavati Schmitz, S., Skancke, E., Morris, J., Dupont, Nana, Argyle, D., Sánchez, S., Spohr, A., Graarup-Hansen, K., Nielsen, Lise Nikolic & Cirera, Susanna, 2024, In: Journal of Veterinary Internal Medicine. 38, 1, p. 741 1 p., ESCG-O-3.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Mitral valve transcriptome analysis in thirty-four age-matched Cavalier King Charles Spaniels with or without congestive heart failure caused by myxomatous mitral valve disease

    Reimann, Maria Josefine, Cremer, Signe Emilie, Christiansen, L., Ibragimov, Emil, Gao, Fei, Cirera, Susanna, Fredholm, Merete, Olsen, Lisbeth Høier & Karlskov-Mortensen, Peter, 2024, In: Mammalian Genome. 35, 1, p. 77-89 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs

    Zeng, H., Zhang, W., Lin, Q., Gao, Y., Teng, J., Xu, Z., Cai, X., Zhong, Z., Wu, J., Liu, Y., Diao, S., Wei, C., Gong, W., Pan, X., Li, Z., Huang, X., Chen, X., Du, J., Zhao, F., Zhao, Y. & 19 others, Ballester, M., Crespo-Piazuelo, D., Amills, M., Clop, A., Karlskov-Mortensen, Peter, Fredholm, Merete, Li, P., Huang, R., Tang, G., Li, M., Liu, X., Chen, Y., Zhang, Q., Li, J., Yuan, X., Ding, X., Fang, L., Zhang, Z. & The PigGTEx Consortium, T. P. C., 2024, In: Nucleic Acids Research. 52, D1, p. D980-D989 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Relationship between syringomyelia and myxomatous mitral valve disease in Cavalier King Charles spaniels

    Bach, Maiken Bayer Thode, Stougaard, C. L., Thøfner, M. S., Reimann, Maria Josefine, Westrup, U., Koch, Jørgen, Fredholm, Merete, Martinussen, Torben, Berendt, Mette & Olsen, Lisbeth Høier, 2024, In: Journal of Veterinary Internal Medicine. 38, 2, p. 904-912 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2023
  7. Published

    Association of serum and fecal microRNA profiles in cats with gastrointestinal cancer and chronic inflammatory enteropathy

    Brogaard, L., Lyngby, Janne Graarup, Kristensen, Annemarie T., Fredholm, Merete, Bjørnvad, Charlotte Reinhard, Salavati Schmitz, S., Skancke, E., Morris, J. S., Dupont, Nana, Argyle, D., Sánchez, A., Spohr, A., Graarup-Hansen, K., Nielsen, Lise Nikolic & Cirera, Susanna, 2023, In: Journal of Veterinary Internal Medicine. 37, 5, p. 1738-1749

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Evaluation of the value of genetic testing for cystinuria in the Danish population of English bulldogs

    Fitzwilliams, Therese Emilie Glar, Wolff-Sneedorff, J. L., Fredholm, Merete, Karlskov-Mortensen, Peter, Guldbrandtsen, Bernt & Bruun, Camilla Vibeke Sichlau, 2023, In: Animal Genetics. 54, 4, p. 566-569

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Kortlægning af initiativer til at modvirke usund avl

    Bruun, Camilla Vibeke Sichlau, Fredholm, Merete, Proschowsky, Helle Friis & Sandøe, Peter, 2023, In: Dansk Veterinaertidsskrift. 2023, 11, p. 18-22 5 p.

    Research output: Contribution to journal › Journal article › Research

  10. Published

    Mapping of initiatives to prevent inherited diseases and exaggerated phenotypes in dogs

    Bruun, Camilla Vibeke Sichlau, Fredholm, Merete, Proschowsky, Helle Friis & Sandøe, Peter, 2023, Department of Veterinary and Animal Sciences, University of Copenhagen. 67 p.

    Research output: Book/Report › Report › Research

  11. 2022
  12. Published

    Analysis of merged transcriptomic and genomic datasets to identify genes and pathways underlying residual feed intake in growing pigs

    Ibragimov, Emil, Pedersen, Anni Øyan, Xiao, L., Cirera, Susanna, Fredholm, Merete & Karlskov-Mortensen, Peter, 2022, In: Scientific Reports. 12, 21946.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Association of fecal and serum microRNA profiles with gastrointestinal cancer and chronic inflammatory enteropathy in dogs

    Lyngby, Janne Graarup, Gòdia, M., Brogaard, L., Kristensen, Annemarie T., Fredholm, Merete, Skancke, E., Morris, J., Dupont, Nana, Salavati Schmitz, S., Argyle, D., Sánchez, A., Bjørnvad, Charlotte Reinhard, Cirera, Susanna & Nielsen, Lise Nikolic, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 1989-2001

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Modeling microRNA-driven post-transcriptional regulation using exon–intron split analysis in pigs

    Mármol-Sánchez, E., Cirera, Susanna, Zingaretti, L. M., Jacobsen, M. J., Ramayo-Caldas, Y., Jørgensen, Claus Bøttcher, Fredholm, Merete, Cardoso, T. F., Quintanilla, R. & Amills, M., 2022, In: Animal Genetics. 53, 5, p. 613-626

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Pampered pets or poor bastards? The welfare of dogs kept as companion animals

    Meyer, Iben, Forkman, Björn, Fredholm, Merete, Glanville, C., Guldbrandtsen, Bernt, Ruiz Izaguirre, E., Palmer, C. & Sandøe, Peter, 2022, In: Applied Animal Behaviour Science. 251, 105640.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2021
  17. Published

    Diet-Dependent Changes of the DNA Methylome Using a Göttingen Minipig Model for Obesity

    Feng, Y., Cirera, Susanna, Taşöz, E., Liu, Y., Olsen, Lisbeth Høier, Christoffersen, B. Ø., Pedersen, H. D., Ludvigsen, T. P., Kirk, R. K., Schumacher-Petersen, Camilla, Deng, Y., Fredholm, Merete & Gao, Fei, 2021, In: Frontiers in Genetics. 12, 632859.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Exercise-Associated Sudden Death in Finnish Standardbred and Coldblooded Trotters - A Case Series With Pedigree Analysis

    Trachsel, D. S., Callø, Kirstine, Mykkänen, A. K., Raistakka, P., Anttila, M., Fredholm, Merete, Tala, M., Lamminpää, K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: Journal of Equine Veterinary Science. 104, 103694.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D

    Skedsmo, F. S., Espenes, A., Tranulis, M. A., Matiasek, K., Gunnes, G., Bjerkås, I., Moe, L., Røed, S. S., Berendt, Mette, Fredholm, Merete, Rohdin, C., Shelton, G. D., Bruheim, P., Stafsnes, M. H., Bartosova, Z., Hermansen, L. C., Stigen, Ø. & Jäderlund, K. H., 2021, In: Neuromuscular Disorders. 31, 1, p. 56-68

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Kan vi bruge den nye DNA-test for diskusprolaps?

    Bruun, Camilla Vibeke Sichlau & Fredholm, Merete, 2021, In: Gravhunden. 2021, 3, p. 29-31 3 p.

    Research output: Contribution to journal › Journal article › Communication

  21. Published

    Pig genome functional annotation enhances the biological interpretation of complex traits and human disease

    Pan, Z., Yao, Y., Yin, H., Cai, Z., Wang, Y., Bai, L., Kern, C., Halstead, M., Chanthavixay, G., Trakooljul, N., Wimmers, K., Sahana, G., Su, G., Lund, M. S., Fredholm, M., Karlskov-Mortensen, P., Ernst, C. W., Ross, P., Tuggle, C. K., Fang, L. & 1 others, Zhou, H., 2021, In: Nature Communications. 12, 1, 5848.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Stor andel af Labrador retrievere i Danmark bærer den nedarvede øjensygdom Stargardt disease

    Mørch, A., Panholm, L., Ysbæk-Nielsen, K., Knudsen, J. K., Sandøe, Peter & Fredholm, Merete, 2021, In: Dansk Veterinærtidsskrift. 2021, 7, p. 25-27 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The first genome-wide association study concerning idiopathic epilepsy in Petit Basset Griffon Vendeen

    Deschain, T., Fabricius, J., Berendt, Mette, Fredholm, Merete & Karlskov-Mortensen, Peter, 2021, In: Animal Genetics. 52, 5, p. 762-766

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Unraveling molecular mechanisms involved in the development of leptin resistance using the pig as a model

    Mármol-Sánchez, E., Artman, J. S., Fredholm, Merete & Cirera, Susanna, 2021, In: Animal Genetics. 52, 1, p. 55-65

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2020
  27. Published

    Arctic-adapted dogs emerged at the Pleistocene-Holocene transition

    Sinding, M. H. S., Gopalakrishnan, S., Ramos-Madrigal, J., de Manuel, M., Pitulko, V. V., Kuderna, L., Feuerborn, T. R., Frantz, L. A. F., Vieira, F. G., Niemann, J., Samaniego Castruita, J. A., Carøe, C., Andersen-Ranberg, E. U., Jordan, P. D., Pavlova, E. Y., Nikolskiy, P. A., Kasparov, A. K., Ivanova, V. V., Willerslev, E., Skoglund, P. & 15 others, Fredholm, Merete, Wennerberg, S. E., Heide-Jørgensen, M. P., Dietz, R., Sonne, C., Meldgaard, Morten, Dalén, L., Larson, G., Petersen, Bent, Sicheritz-Pontén, Thomas, Bachmann, L., Wiig, Ø., Marques-Bonet, T., Hansen, Anders Johannes & Gilbert, M Thomas P, 2020, In: Science (New York, N.Y.). 368, 6498, p. 1495-1499 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Breeding schemes for intervertebral disc disease in dachshunds: Is disc calcification score preferable to genotyping of the FGF4 retrogene insertion on CFA12?

    Bruun, Camilla Vibeke Sichlau, Bruun, C., Marx, T., Proschowsky, Helle Friis & Fredholm, Merete, 2020, In: Canine medicine and genetics. 7, 18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Differential microRNA expression-profiles in feces and serum of dogs with chronic inflammatory enteropathy and with gastrointestinal disease

    Lyngby, Janne Graarup, Godia, M., Kristensen, Annemarie T., Fredholm, Merete, Skancke, E., Salvati, S., Morris, J. S., Argyle, D., Bjørnvad, Charlotte Reinhard, Sánchez, A., Dupont, Nana, Cirera, Susanna & Nielsen, Lise Nikolic, 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research

  30. Published

    Fgf21 regulates hepatic metabolic pathways to improve steatosis and inflammation

    Keinicke, H., Sun, G., Mentzel, Caroline M. Junker, Fredholm, Merete, John, L. M., Andersen, B., Raun, K. & Kjaergaard, M., 2020, In: Endocrine Connections. 9, 8, p. 755-768 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Genome wide association study of 40 clinical measurements in eight dog breeds

    Momozawa, Y., Merveille, A. C., Battaille, G., Wiberg, M., Koch, Jørgen, Willesen, Jakob, Proschowsky, Helle Friis, Gouni, V., Chetboul, V., Tiret, L., Fredholm, Merete, Seppälä, E. H., Lohi, H., Georges, M. & Lequarré, A. S., 2020, In: Scientific Reports. 10, 6520.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Genomic diversity revealed by whole-genome sequencing in three Danish commercial pig breeds

    Cai, Z., Sarup, P., Ostersen, T., Nielsen, B., Fredholm, Merete, Karlskov-Mortensen, Peter, Sørensen, P., Jensen, J., Guldbrandtsen, B., Lund, M. S., Christensen, Ole Fredslund Borg & Sahana, G., 2020, In: Journal of Animal Science. 98, 7, skaa229.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels

    Zhang, Q., Cai, Z., Lhomme, M., Sahana, G., Lesnik, P., Guerin, M., Fredholm, Merete & Karlskov-Mortensen, Peter, 2020, In: Scientific Reports. 10, 1, 14 p., 18434.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    NASH-inducing Diets in Göttingen Minipigs

    Pedersen, H. D., Galsgaard, E. D., Christoffersen, B., Cirera, Susanna, Holst, D., Fredholm, Merete & Latta, M., 2020, In: Journal of Clinical and Experimental Hepatology. 10, 3, p. 211-221

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation

    Cirera, Susanna, Taşöz, E., Juul Jacobsen, M., Schumacher-Petersen, Camilla, Østergaard Christoffersen, B., Kaae Kirk, R., Pagh Ludvigsen, T., Hvid, H., Duelund Pedersen, H., Olsen, Lisbeth Høier & Fredholm, Merete, 2020, In: Nutrition and Diabetes. 10, 1, 12 p., 9.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Validation of DNA test for hip dysplasia failed in Danish Labrador Retrievers

    Bruun, Camilla Vibeke Sichlau, Bank, A., Ström, A., Proschowsky, Helle Friis & Fredholm, Merete, 2020, In: Animal Genetics. 51, 4, p. 617-619

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. 2019
  38. Published

    Breeding French bulldogs so that they breathe well-A long way to go

    Ravn-Mølby, E., Sindahl, L., Nielsen, Søren Saxmose, Bruun, Camilla Vibeke Sichlau, Sandøe, Peter & Fredholm, Merete, 2019, In: PLoS ONE. 14, 12, 14 p., e0226280.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism

    Jacobsen, M. J., Havgaard, Jakob Hull, Anthon, Christian, Mentzel, Caroline M. Junker, Cirera, Susanna, Krogh, P. M., Pundhir, Sachin, Karlskov-Mortensen, Peter, Bruun, C. S., Lesnik, P., Guerin, M., Gorodkin, Jan, Jørgensen, Claus Bøttcher, Fredholm, Merete & Barrès, Romain, 2019, In: Frontiers in Genetics. 10, 13 p., 1268.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Evaluation of fecal microRNA stability in healthy cats

    Lyngby, Janne Graarup, Kristensen, Annemarie T., Fredholm, Merete, Nielsen, Lise Nikolic & Cirera, Susanna, 2019, In: Veterinary Clinical Pathology. 48, 3, p. 455-460 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite-host cross talk

    Hansen, E. P., Fromm, B., Andersen, S. D., Marcilla, A., Andersen, K. L., Borup, A., Williams, Andrew Richard, Jex, A. R., Gasser, R. B., Young, N. D., Hall, R. S., Stensballe, A., Ovchinnikov, V., Yan, Y., Fredholm, Merete, Thamsborg, Stig Milan & Nejsum, P., 2019, In: Journal of Extracellular Vesicles. 8, 1, 14 p., 1578116.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

    Ameen, C., Feuerborn, T. R., Brown, S. K., Linderholm, A., Hulme-Beaman, A., Lebrasseur, O., Sinding, M-H. S., Lounsberry, Z. T., Lin, A. T., Appelt, M., Bachmann, L., Betts, M., Britton, K., Darwent, J., Dietz, R., Fredholm, M., Gopalakrishnan, S., Goriunova, O. I., Grønnow, B., Haile, J. & 39 others, Hallsson, J. H., Harrison, R., Heide-Jørgensen, M. P., Knecht, R., Losey, R. J., Masson-MacLean, E., McGovern, T. H., McManus-Fry, E., Meldgaard, Morten, Midtdal, Å., Moss, M. L., Nikitin, I. G., Nomokonova, T., Pálsdóttir, A. H., Perri, A., Popov, A. N., Rankin, L., Reuther, J. D., Sablin, M., Schmidt, A. L., Shirar, S., Smiarowski, K., Sonne, C., Stiner, M. C., Vasyukov, M., West, C. F., Ween, G. B., Wennerberg, S. E., Wiig, Ø., Woollett, J., Dalén, L., Hansen, Anders Johannes, Gilbert, M Thomas P, Sacks, B. N., Frantz, L., Larson, G., Dobney, K., Darwent, C. M. & Evin, A., 2019, In: Proceedings. Biological sciences. 286, 1916, p. 20191929

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. 2018
  44. Published

    Kamphund eller ej?

    Fredholm, Merete & Sandøe, Peter, 23 Feb 2018, In: Weekendavisen: Ideer. p. 4-5 2 p.

    Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication

  45. Published

    Ascaris suum infection down-regulates inflammatory pathways in the pig intestine in vivo and in human dendritic cells in vitro

    Midttun, H. L. E., Acevedo, N., Skallerup, P., Almeida, Sara dos Santos, Skovgaard, K., Andresen, Lars, Skov, Søren, Caraballo, L., van Die, I., Jørgensen, Claus Bøttcher, Fredholm, Merete, Thamsborg, Stig Milan, Nejsum, P. & Williams, Andrew Richard, 2018, In: The Journal of Infectious Diseases. 217, 2, p. 310-319

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    A targeted genotyping approach enhances identification of variants in taste receptor and appetite/reward genes of potential functional importance for obesity-related porcine traits

    Cirera, Susanna, Clop, A., Jacobsen, M. J., Guerin, M., Lesnik, P., Jørgensen, Claus Bøttcher, Fredholm, Merete & Karlskov-Mortensen, Peter, 2018, In: Animal Genetics. 49, 2, p. 110–118

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Analysis of porcine body size variation using re-sequencing data of miniature and large pigs 06 Biological Sciences 0604 Genetics

    Reimer, C., Rubin, C. J., Sharifi, A. R., Ha, N. T., Weigend, S., Waldmann, K. H., Distl, O., Pant, S. D., Fredholm, Merete, Schlather, M. & Simianer, H., 2018, In: BMC Genomics. 19, 17 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Brug af DNA-markører: til at bestemme, om en hund tilhører en forbudt race

    Fredholm, Merete, Pedersen, L., Laursen, M. G. & Sandøe, Peter, 2018, In: Dansk Veterinaertidsskrift. 3, p. 26-28/ 3 p.

    Research output: Contribution to journal › Journal article › Research

  49. Published

    Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs

    Mentzel, Caroline M. Junker, Cardoso, T. F., Pipper, C. B., Jacobsen, M. J., Jørgensen, Claus Bøttcher, Cirera, Susanna & Fredholm, Merete, 2018, In: Molecular Genetics and Genomics. 293, 1, p. 129–136 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Early microbial colonization affects DNA methylation of genes related to intestinal immunity and metabolism in preterm pigs

    Pan, X., Gong, D., Nguyen, Duc Ninh, Zhang, X., Hu, Q., Lu, H., Fredholm, Merete, Sangild, Per Torp & Gao, Fei, 2018, In: D N A Research. 25, 3, p. 287–296

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Identification of the mutation causing progressive retinal atrophy in Old Danish Pointing Dog

    Karlskov-Mortensen, Peter, Proschowsky, Helle Friis, Gao, Fei & Fredholm, Merete, 2018, In: Animal Genetics. 49, 3, p. 237-241 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Interbreed variation in serum serotonin (5-hydroxytryptamine) concentration in updates healthy dogs

    Hoglund, K., Haggstrom, J., Hanås, S., Merveille, A. -., Gouni, V., Wiberg, M., Willesen, Jakob, Mc Entee, K., Sorensen, L. M., Tiret, L., Seppala, E. H., Lohi, H., Chetboul, V., Fredholm, Merete, Lequarre, A. -. & Ljungvall, I., 2018, In: Journal of Veterinary Cardiology. 20, 4, p. 244-253

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Interbreed variation of biomarkers of lipid and glucose metabolism in dogs

    Gomez-fernandez-blanco, C., Peeters, D., Moyse, E., Farnir, F., Höglund, K., Gouni, V., Wiberg, M., Lundgren Willesen, J., Hanås, S., Mcentee, K., Tiret, L., Häggström, J., Lohi, H., Chetboul, V., Fredholm, Merete, Seppälä, E. H., Lequarré, A. & Merveille, A., 2018, In: Veterinary Clinical Pathology. 47, 4, p. 582-588

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2017
  55. Published

    Circulating let-7g is down-regulated in Bernese Mountain dogs with disseminated histiocytic sarcoma and carcinomas: a prospective study

    Børresen, Betina, Nielsen, Lise Nikolic, Jessen, Lisbeth Rem, Kristensen, Annemarie T., Fredholm, Merete & Cirera, Susanna, Jun 2017, In: Veterinary and Comparative Oncology. 15, 2, p. 525–533 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Transcriptional immune response in mesenteric lymph nodes in pigs with different levels of resistance to Ascaris suum

    Skallerup, P., Nejsum, P., Cirera, Susanna, Skovgaard, K., Pipper, C. B., Fredholm, Merete, Jørgensen, Claus Bøttcher & Thamsborg, Stig Milan, Mar 2017, In: Acta Parasitologica. 62, 1, p. 141-153 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Dyrevelfærdsmæssige problemer i forbindelse med hundeavl

    Fredholm, Merete, 2017, In: Dansk Veterinaertidsskrift. 100, 6, p. 6-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Dyrevelfærdsmæssige problemer i forbindelse med hundeavl

    Fredholm, Merete, 2017, In: Norsk Veterinaer-Tidsskrift. 2017, 4, p. 236-239

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    FEELnc: A tool for long non-coding RNA annotation and its application to the dog transcriptome

    Wucher, V., Legeai, F., Hédan, B., Rizk, G., Lagoutte, L., Leeb, T., Jagannathan, V., Cadieu, E., David, A., Lohi, H., Cirera Salicio, S., Fredholm, M., Botherel, N., Leegwater, P. A. J., Le Béguec, C., Fieten, H., Johnson, J. J., Alföldi, J., André, C., Lindblad-Toh, K. & 2 others, Hitte, C. & Derrien, T., 2017, In: Nucleic Acids Research. 45, 8, 12 p., e57.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Fat and carbohydrate content in the diet induces drastic changes in gene expression in young Göttingen minipigs

    Mentzel, Caroline M. Junker, Figueiredo Cardoso, T., Haagensen, A. M. J., Sørensen, Dorte Bratbo, Fredholm, Merete & Cirera, Susanna, 2017, In: Mammalian Genome. 28, 5-6, p. 166-175 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Haplotypes on pig chromosome 3 distinguish metabolically healthy from unhealthy obese individuals

    Frederiksen, S. D., Karlskov-Mortensen, Peter, Pant, S. D., Guerin, M., Lesnik, P., Jørgensen, Claus Bøttcher, Cirera, Susanna, Bruun, Camilla Vibeke Sichlau, Mark, T. & Fredholm, Merete, 2017, In: PLoS ONE. 12, 6, 13 p., e0178828.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Re-emergence of hereditary polyneuropathy in scandinavian alaskan malamute dogs-old enemy or new entity? A case series

    Jäderlund, K. H., Rohdin, C., Berendt, Mette, Stigen, Ø., Fredholm, Merete, Espenes, A., Bjerkås, I. & Moe, L., 2017, In: Acta Veterinaria Scandinavica. 59, 1, 4 p., 26.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. 2016
  64. Published

    Joint profiling of miRNAs and mRNAs reveals miRNA mediated gene regulation in the Göttingen minipig obesity model

    Mentzel, Caroline M. Junker, Alkan, F., Keinicke, H., Jacobsen, M. J., Gorodkin, Jan, Fredholm, Merete & Cirera, Susanna, 30 Nov 2016, In: P L o S One. 11, 11, 16 p., e0167285.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs

    Jacobsen, M. J., Havgaard, Jakob Hull, Mentzel, Caroline M. Junker, Sørensen, P. M., Pundhir, Sachin, Anthon, Christian, Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Jørgensen, Claus Bøttcher, Barrès, Romain & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement 4, p. 46-47 2 p., P2019.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  66. Published

    Focus on atherosclerosis and the pig as a model to identify genes affecting cholesterol and other plasma lipid levels.

    Karlskov-Mortensen, Peter, Frederiksen, S. D., Pant, S. D., Cirera, Susanna, Jørgensen, Claus Bøttcher, Bruun, Camilla Vibeke Sichlau, Mark, T. & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement4, p. 152-152 1 p., P6009.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  67. Published

    Differential Analysis of the Nasal Microbiome of Pig Carriers or Non-Carriers of Staphylococcus aureus

    Espinosa-Gongora, C., Larsen, N., Schønning, Kristian, Fredholm, Merete & Guardabassi, Luca, 10 Aug 2016, In: P L o S One. 11, 8, 13 p., 0160331.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Hepatic expression of inflammatory genes and microRNAs in pigs with high "cholesteryl ester transfer protein" (CETP) activity

    Cirera, Susanna, Tørsleff, B. C. J., Ritz, C., Fredholm, Merete, Heegaard, P. M. H. & Skovgaard, K., 30 May 2016, In: Mammalian Genome. 27, 9, p. 503-510 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    A large insertion in intron 2 of the TYRP1 gene associated with American Palomino phenotype in American mink

    Cirera, Susanna, Markakis, M. N., Kristensen, Thea, Vissenberg, K., Fredholm, Merete, Christensen, Knud Arnbjerg & Anistoroaei, R. M., Apr 2016, In: Mammalian Genome. 27, 3, p. 135-143 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Effect of breed on plasma endothelin-1 concentration, plasma renin activity, and serum cortisol concentration in healthy dogs

    Höglund, K., Lequarré, A., Ljungvall, I., Mc Entee, K., Merveille, A., Wiberg, M., Gouni, V., Willesen, Jakob, Hanås, S., Wess, G., Mejer Sørensen, L., Tiret, L., Kierczak, M., Forsberg, S. K. G., Seppälä, E., Lindblad-Toh, K., Lohi, H., Chetboul, V., Fredholm, Merete & Häggström, J., Mar 2016, In: Journal of Veterinary Internal Medicine. 30, 2, p. 566-573 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Discrepancy in compliance between the clinical and genetic diagnosis of choroidal hypoplasia in Danish Rough Collies and Shetland Sheepdogs

    Fredholm, Merete, Larsen, R. C., Jönsson, M., Söderlund, M. A., Hardon, T. & Proschowsky, Helle Friis, 6 Jan 2016, In: Animal Genetics. 47, 2, p. 250-252 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity

    Jacobsen, M. J., Mentzel, Caroline M. Junker, Olesen, A. S., Huby, T., Jørgensen, Claus Bøttcher, Barrès, Romain, Fredholm, Merete & Simar, D., 2016, In: Journal of Diabetes Research. 2016, p. 1-11 8539057.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Identification of protein-damaging mutations in 10 swine taste receptors and 191 appetite-reward genes

    Clop, A., Sharaf, A., Castelló, A., Ramos-Onsins, S., Cirera, Susanna, Mercadé, A., Derdak, S., Beltran, S., Huisman, A., Fredholm, Merete, van As, P. & Sánchez, A., 2016, In: BMC Genomics. 17, 17 p., 685.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Physical training and weight loss in dogs lead to transcriptional changes in genes involved in the glucose-transport pathway in muscle and adipose tissues

    Herrera Uribe, J., Vitger, Anne Désiré, Ritz, C., Fredholm, Merete, Bjørnvad, Charlotte Reinhard & Cirera, Susanna, 2016, In: The Veterinary Journal. 208, p. 22-27 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    The prevalence of the electrocardiographic J wave in the Petit Basset Griffon Vendéen compared to 10 different dog breeds

    Rudling, E. H., Schlamowitz, S., Pipper, C. B., Nilsson, E., Höllmer, M., Willesen, Jakob, Berendt, Mette, Fredholm, Merete, Gulløv, C. H., Christiansen, M. & Koch, Jørgen, 2016, In: Journal of Veterinary Cardiology. 18, 1, p. 26-33 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. 2015
  77. Published

    Expression study of GLUT4 translocation-related genes in a porcine pre-diabetic model

    Kristensen, Thea, Fredholm, Merete & Cirera, Susanna, Dec 2015, In: Mammalian Genome. 26, 11, p. 650-657 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    An integrative systems genetics approach reveals potential causal genes and pathways related to obesity

    Kogelman, L., Zhernakova, D. V., Westra, H., Cirera, Susanna, Fredholm, Merete, Franke, L. & Kadarmideen, H., 20 Oct 2015, In: Genome Medicine. 7, 15 p., 105.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans

    Pant, S. D., Karlskov-Mortensen, Peter, Jacobsen, M. J., Cirera, Susanna, Kogelman, L., Bruun, Camilla Vibeke Sichlau, Mark, T., Jørgensen, Claus Bøttcher, Grarup, Niels, Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, Oluf Borbye, Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 8 Sep 2015, In: PLOS ONE. 10, 9, 22 p., e0137356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Prevalence and heritability of distichiasis in the English Cocker spaniel

    Petersen, T., Proschowsky, Helle Friis, Hardon, T., Nyhuus Rasch, S. & Fredholm, Merete, 2 Aug 2015, In: Canine Genetics and Epidemiology. 2, 6 p., 11.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Gender and obesity specific MicroRNA expression in adipose tissue from lean and obese pigs

    Mentzel, Caroline M. Junker, Anthon, Christian, Jacobsen, M. J., Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Jørgensen, Claus Bøttcher, Gorodkin, Jan, Cirera, Susanna & Fredholm, Merete, 29 Jul 2015, In: P L o S One. 10, 7, 19 p., e0131650.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Circulating miRNAs as biomarkers for disseminated histiocytic sarcoma in Bernese Mountain dogs - a prospective study

    Børresen, Betina, Nielsen, Lise Nikolic, Jessen, Lisbeth Rem, Kristensen, Annemarie T., Fredholm, Merete & Cirera, Susanna, 2015.

    Research output: Contribution to conference › Conference abstract for conference › Research

  83. Published

    Detection of a quantitative trait locus associated with resistance to infection with Trichuris suis in pigs

    Skallerup, P., Thamsborg, Stig Milan, Jørgensen, Claus Bøttcher, Mejer, Helena, Göring, H. H. H., Archibald, A. L., Fredholm, Merete & Nejsum, P., 2015, In: Veterinary Parasitology. 210, 3-4, p. 264-269 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Genome-wide association study reveals a locus for nasal carriage of Staphylococcus aureus in Danish crossbred pigs

    Skallerup, P., Gongora, C. E., Jørgensen, Claus Bøttcher, Guardabassi, Luca & Fredholm, Merete, 2015, In: B M C Veterinary Research. 11, 8 p., 290.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Prevalence and heritability of symptomatic syringomyelia in Cavalier King Charles Spaniels and long-term outcome in symptomatic and asymptomatic littermates

    Thøfner, M. S., Stougaard, C. L., Westrup, U., Madry, A. A., Knudsen, C. S., Berg, H., Jensen, C. S. E., Handby, R. M. L., Gredal, Hanne Birgit, Fredholm, Merete & Berendt, Mette, 2015, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 29, 1, p. 243-250 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    The shepherds' tale: a genome-wide study across 9 dog breeds implicates two loci in the regulation of fructosamine serum concentration in Belgian shepherds

    Forsberg, S. K. G., Kierczak, M., Ljungvall, I., Merveille, A-C., Gouni, V., Wiberg, M., Willesen, J., Hanås, S., Lequarré, A-S., Mejer Sørensen, L., Tiret, L., McEntee, K., Seppälä, E., Koch, J., Battaille, G., Lohi, H., Fredholm, M., Chetboul, V., Häggström, J., Carlborg, Ö. & 2 others, Lindblad-Toh, K. & Höglund, K., 2015, In: PLOS ONE. 10, 5, 17 p., e0123173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. 2014
  88. Published

    Genomic Predictions of Obesity Related Phenotypes in a Pig model using GBLUP and Bayesian Approaches

    Pant, S. D., Do, D. N., Janss, L., Fredholm, Merete & Kadarmideen, H., 28 Aug 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  89. Published

    Detection of a quantitative trait locus associated with resistance to whipworm infections in pigs

    Skallerup, P., Thamsborg, Stig Milan, Jørgensen, Claus Bøttcher, Göring, H. H., Fredholm, Merete & Nejsum, P., 25 Aug 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  90. Published

    Systems genetics analysis of obesity in a porcine model using WISH network method

    Kogelman, L., Pant, S. D., Karjalainen, J., Franke, L., Fredholm, Merete & Kadarmideen, H., 16 Aug 2014. 3 p.

    Research output: Contribution to conference › Paper › Research

  91. Published

    A hereditary disposition for bovine peripheral nerve sheath tumors in Danish Holstein cattle

    Grossi, A. B., Agerholm, Jørgen Steen, Christensen, Knud Arnbjerg, Jensen, Henrik Elvang, Leifsson, Páll S., Bendixen, C., Karlskov-Mortensen, Peter & Fredholm, Merete, 2014, In: Acta Veterinaria Scandinavica (Online). 56, 6 p., 85.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Avl for forbedret velfærd hos racehunde

    Meyer, Iben, Forkman, Björn, Fredholm, Merete, Knudsen, V., Lund, Thomas Bøker, Nissen, Merete Holst, Proschowsky, Helle Friis & Sandøe, Peter, 2014.

    Research output: Contribution to conference › Poster › Research

  93. Published

    Breed differences in natriuretic peptides in healthy dogs

    Sjöstrand, K., Wess, G., Ljungvall, I., Häggström, J., Merveille, A-C., Wiberg, M., Gouni, V., Willesen, J., Hanås, S., Lequarré, A-S., Sørensen, L. M., Wolf, J., Tiret, L., Kierczak, M., Forsberg, S., McEntee, K., Battaille, G., Seppälä, E., Lindblad-Toh, K., Georges, M. & 4 others, Lohi, H., Chetboul, V., Fredholm, Merete & Höglund, K., 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 451-457 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Clinical findings and prevalence of the mutation associated with Primary ciliary dyskinesia in Old English Sheepdogs

    Merveille, A., Battaille, G., Billen, F., Deleuze, S., Fredholm, Merete, Thomas, A., Clercx, C. & Lequarre, A., 2014, In: Journal of Veterinary Internal Medicine. 28, 3, p. 771-778 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Expression studies of six human obesity-related genes in seven tissues from divergent pig breeds

    Cirera, Susanna, Jensen, M. S., Elbrønd, V. S., Moesgaard, S. G., Christoffersen, B. O., Kadarmideen, H., Skovgaard, K., Bruun, Camilla Vibeke Sichlau, Karlskov-Mortensen, Peter, Jørgensen, Claus Bøttcher & Fredholm, Merete, 2014, In: Animal Genetics. 45, 1, p. 59-66 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Functional study of a genetic marker allele associated with resistance to Ascaris suum in pigs

    Skallerup, P., Thamsborg, Stig Milan, Jørgensen, Claus Bøttcher, Enemark, H. L., Yoshida, A., Göring, H. H., Fredholm, Merete & Nejsum, P., 2014, In: Parasitology. 141, 6, p. 777-787 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity

    Pant, S. D., Karlskov-Mortensen, Peter, Cirera, Susanna, Kogelman, L., Jacobsen, M. J., Bruun, Camilla Vibeke Sichlau, Jørgensen, Claus Bøttcher, Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 2014. 4 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  98. Published

    Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine model

    Kogelman, L., Cirera, Susanna, Zhernakova, D. V., Fredholm, Merete, Franke, L. & Kadarmideen, H., 2014, In: B M C Genomics. 7, 16 p., 57.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Identifying QTL and genetic correlations between fur quality traits in mink (Neovison vison)

    Thirstrup, J. P., Anistoroaei, R. M., Guldbrandtsen, B., Christensen, Knud Arnbjerg, Fredholm, Merete & Nielsen, V. H., 2014, In: Animal Genetics. 45, 1, p. 105-110 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Perosomus elumbis in Danish Holstein cattle

    Agerholm, Jørgen Steen, Holm, W., Schmidt, M., Hyttel, P., Fredholm, Merete & McEvoy, Fintan, 2014, In: B M C Veterinary Research. 10, 6 p., 227.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Quantitative and systems genetics analyses of lipid profiles in a pig model for obesity

    Frederiksen, S. D., Pant, S. D., Kogelman, L., Fredholm, Merete & Kadarmideen, H., 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  102. Published

    Selektiv avl af racehunde og -katte: kan den ske på en velfærdsmæssigt forsvarlig måde?

    Sandøe, Peter, Meyer, Iben, Fredholm, Merete & Proschowsky, Helle Friis, 2014, Dyrevelfærd i Danmark 2014: Videncenter for dyrevelfærd. Fødevarestyrelsen, p. 36-48 13 p.

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

  103. Published

    Structured RNAs and synteny regions in the pig genome

    Anthon, Christian, Tafer, H., Havgaard, Jakob Hull, Thomsen, B., Hedegaard, J., Seemann, Ernst Stefan, Pundhir, Sachin, Kehr, S., Bartschat, S., Nielsen, M., Nielsen, R. O., Fredholm, Merete, Stadler, P. F. & Gorodkin, Jan, 2014, In: BMC Genomics. 15, 27 p., 459.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Systems biology and RNA-Seq analyses to detect biomarkers for metabolic syndrome in a porcine model

    Mantas, P., Kogelman, L., Cirera, Susanna, Fredholm, Merete & Kadarmideen, H., 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  105. Published

    Systems genetics analysis of RNA-Seq data to unravel the genetics of obesity using a porcine model

    Kogelman, L., Zhernakova, D. V., Westra, H., Cirera, Susanna, Fredholm, Merete, Franke, L. & Kadarmideen, H., 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  106. Published

    Systems genetics analysis of obesity using RNA-Seq data in an F2 pig resource population

    Kogelman, L., Zhernakova, D. V., Westra, H., Cirera, Susanna, Fredholm, Merete, Franke, L. & Kadarmideen, H., 2014, Proceedings, 10th World Congress of Genetics Applied to Livestock Production. 3 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  107. Published

    Systems genetics of obesity in an F2 pig model by genome-wide association, genetic network and pathway analyses

    Kogelman, L., Pant, S. D., Fredholm, Merete & Kadarmideen, H., 2014, In: Frontiers in Genetics. 5, 15 p., 214.

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    The WISH network method applied to obesity in an F2 pig population

    Kogelman, L., Pant, S. D., Karjalainen, J., Franke, L., Fredholm, Merete & Kadarmideen, H., 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  109. Published

    Vad är fel med min bulldogg? att förebygga avel av hundar med brakycefalt syndrom

    Sandøe, Peter, Hansen, I. K., Göransson, M., Eriksen, Thomas & Fredholm, Merete, 2014, In: Svensk Veterinaertidning. 2014, 8-9, p. 23-27 5 p.

    Research output: Contribution to journal › Journal article › Research

  110. 2013
  111. Published

    Gene expression in mesenteric lymph nodes of pigs with two different genotypes associated with resistance or susceptibility to Ascaris suum

    Skallerup, P., Nejsum, P., Jørgensen, Claus Bøttcher, Cirera, Susanna, Skovgaard, K., Pipper, C. B., Fredholm, Merete & Thamsborg, Stig Milan, 10 Sep 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  112. Published

    Gene expression in mesenteric lymph nodes of pigs with two different genotypes associated with resistance or susceptibility to Ascaris suum

    Skallerup, P., Nejsum, P., Jørgensen, Claus Bøttcher, Cirera, Susanna, Skovgaard, K., Pipper, C. B., Fredholm, Merete & Thamsborg, Stig Milan, 26 Aug 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

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