Mads Gyrd-Hansen
Professor
Skin Immunology Research Center
Nørre Allé 14
2200 København N
- 2018
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling
Hrdinka, M., Schlicher, L., Dai, B., Pinkas, D. M., Bufton, J. C., Picaud, S., Ward, J. A., Rogers, C., Suebsuwong, C., Nikhar, S., Cuny, G. D., Huber, K. V., Filippakopoulos, P., Bullock, A. N., Degterev, A. & Gyrd-Hansen, Mads, 3 Sep 2018, In: The EMBO Journal. 37, 17Research output: Contribution to journal › Journal article › Research › peer-review
Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1
Prabakaran, T., Bodda, C., Krapp, C., Zhang, B-C., Christensen, M. H., Sun, C., Reinert, L., Cai, Y., Jensen, S. B., Skouboe, M. K., Nyengaard, J. R., Thompson, C. B., Lebbink, R. J., Sen, G. C., van Loo, G., Nielsen, R., Komatsu, M., Nejsum, L. N., Jakobsen, M. R., Gyrd-Hansen, M. & 1 others, , 13 Apr 2018, In: The EMBO Journal. 37, 8, e97858.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
The Met1-Linked Ubiquitin Machinery: Emerging Themes of (De)regulation
Hrdinka, M. & Gyrd-Hansen, Mads, 19 Oct 2017, In: Molecular Cell. 68, 2, p. 265-280 16 p.Research output: Contribution to journal › Review › Research › peer-review
Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease
Schwerd, T., Pandey, S., Yang, H-T., Bagola, K., Jameson, E., Jung, J., Lachmann, R. H., Shah, N., Patel, S. Y., Booth, C., Runz, H., Düker, G., Bettels, R., Rohrbach, M., Kugathasan, S., Chapel, H., Keshav, S., Elkadri, A., Platt, N., Muise, A. M. & 8 others, , Jun 2017, In: Gut. 66, 6, p. 1060-1073 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
All roads lead to ubiquitin
Gyrd-Hansen, Mads, 2017, In: Cell Death and Differentiation. 24, 7, p. 1135-1136 2 p.Research output: Contribution to journal › Editorial › Research
Cell scientist to watch - Mads Gyrd-Hansen
Gyrd-Hansen, Mads, 2017, In: Journal of Cell Science. 130, 12, p. 1981-1983 3 p.Research output: Contribution to journal › Comment/debate › Research
- 2016
- Published
OTULIN deficiency causes auto-inflammatory syndrome
Fiil, Berthe Katrine & Gyrd-Hansen, Mads, Nov 2016, In: Cell Research. 26, 11, p. 1176-1177 2 p.Research output: Contribution to journal › Journal article › Commissioned
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
Elliott, P. R., Leske, D., Hrdinka, M., Bagola, K., Fiil, Berthe Katrine, McLaughlin, S. H., Wagstaff, J., Volkmar, N., Christianson, J. C., Kessler, B. M., Freund, S. M. V., Komander, D. & Gyrd-Hansen, Mads, 15 Sep 2016, In: Molecular Cell. 63, 6, p. 990-1005 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling
Hrdinka, M., Fiil, Berthe Katrine, Zucca, M., Leske, D., Bagola, K., Yabal, M., Elliott, P. R., Damgaard, R. B., Komander, D., Jost, P. J. & Gyrd-Hansen, Mads, 29 Mar 2016, In: Cell Reports. 14, 12, p. 2846-58 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors
Canning, P., Ruan, Q., Schwerd, T., Hrdinka, M., Maki, J. L., Saleh, D., Suebsuwong, C., Ray, S., Brennan, P. E., Cuny, G. D., Uhlig, H. H., Gyrd-Hansen, Mads, Degterev, A. & Bullock, A. N., 17 Sep 2015, In: Cell Chemical Biology. 22, 9, p. 1174-84 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4000197
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Molecular basis and regulation of OTULIN-LUBAC interaction
Research output: Contribution to journal › Journal article › Research › peer-review
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41
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The Met1-linked ubiquitin machinery in inflammation and infection
Research output: Contribution to journal › Review › Research › peer-review
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23
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Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
Research output: Contribution to journal › Journal article › Research › peer-review
Published