Lise Arleth

Lise Arleth

Associate Dean of Research

ORCID: 0000-0002-4694-4299

Publication year:
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  1. 2024
  2. Published

    Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering

    Galvagnion-Büll, Céline, Barclay, A., Makasewicz, K., Marlet, Frederik Ravnkilde, Moulin, M., Devos, J. M., Linse, S., Martel, A., Porcar, L., Sparr, E., Pedersen, Martin Cramer, Roosen-Runge, F., Arleth, Lise & Buell, A. K., 2024, In: Physical chemistry chemical physics : PCCP. 26, p. 10998-11013

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Aggregative adherence fimbriae form compact structures as seen by SAXS

    Jønsson, R., Björling, A., Midtgaard, S. R., Jensen, G. V., Skar-Gislinge, Nicholas, Arleth, Lise, Matthews, S., Krogfelt, K. A. & Jenssen, H., 2 Oct 2023, In: Scientific Reports. 13, 1, 7 p., 16516.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Modeling of flexible membrane-bound biomolecular complexes for solution small-angle scattering

    Barclay, A., Kragelund, Birthe Brandt, Arleth, Lise & Pedersen, Martin Cramer, Apr 2023, In: Journal of Colloid and Interface Science. 635, p. 611-621 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Anisotropic protein-protein interactions in dilute and concentrated solutions

    Pasquier, C., Midtgaard, S. R., Polimeni, M., Jorgensen, C. I., Arleth, Lise, Callisen, T. H. & Lund, M., Jan 2023, In: Journal of Colloid and Interface Science. 629, p. 794-804 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase

    Forsberg, Z., Stepnov, A. A., Tesei, Giulio, Wang, Yong, Buchinger, E., Kristiansen, S. K., Aachmann, F. L., Arleth, Lise, Eijsink, V. G. H., Lindorff-Larsen, Kresten & Courtade, G., 2023, In: Journal of Biological Chemistry. 299, 11, 17 p., 105262.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate

    Araya-Secchi, R., Bugge, K., Seiffert, P., Petry, A., Haxholm, G. W., Lindorff-Larsen, Kresten, Pedersen, Stine Helene Falsig, Arleth, Lise & Kragelund, Birthe Brandt, 2023, In: eLife. 12, 27 p., e84645.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Travel light: Essential packing for membrane proteins with an active lifestyle

    Johansen, Nicolai Tidemand, Tidemand, Frederik Grønbæk, Pedersen, Martin Cramer & Arleth, Lise, 2023, In: Biochimie. 205, p. 3-26 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. 2022
  11. Published

    Non-ionic detergent assists formation of supercharged nanodiscs and insertion of membrane proteins

    Tidemand, Frederik Grønbæk, Blemmer, S., Johansen, Nicolai Tidemand, Arleth, Lise & Pedersen, Martin Cramer, 1 Jun 2022, In: Biochimica et Biophysica Acta - Biomembranes. 1864, 6, 10 p., 183884.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Dark peptide discs for the investigation of membrane proteins in supported lipid bilayers: the case of synaptobrevin 2 (VAMP2)

    Luchini, A., Tidemand, Frederik Grønbæk, Johansen, Nicolai Tidemand, Sebastiani, Federica, Corucci, G., Fragneto, G., Cardenas, M. & Arleth, Lise, 2022, In: Nanoscale Advances. 4, 21, p. 4526-4534 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Global fitting of multiple data frames from SEC-SAXS to investigate the structure of next-generation nanodiscs

    Barclay, A., Johansen, Nicolai Tidemand, Tidemand, Frederik Grønbæk, Arleth, Lise & Pedersen, Martin Cramer, 2022, In: Acta Crystallographica Section D: Biological Crystallography. 78, p. 483-493 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Mg2+-dependent conformational equilibria in CorA and an integrated view on transport regulation

    Johansen, Nicolai Tidemand, Bonaccorsi, M., Bengtsen, T., Nørgrd Larsen, Andreas, Tidemand, Frederik Grønbæk, Pedersen, Martin Cramer, Huda, P., Berndtsson, J., Darwish, T., Yepuri, N. R., Martel, A., Pomorski, Thomas Guenther, Bertarello, A., Sansom, M., Rapp, M., Crehuet, R., Schubeis, T., Lindorff-Larsen, Kresten, Pintacuda, G. & Arleth, Lise, 2022, In: eLife. 11, 35 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Structural model of tissue factor (TF) and TF-factor VIIa complex in a lipid membrane: A combined experimental and computational study

    Luchini, A., Tidemand, Frederik Grønbæk, Araya-Secchi, R., Campana, M., Cárdenas, M. & Arleth, Lise, 2022, In: Journal of Colloid and Interface Science. 623, p. 294-305 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2021
  17. Published

    Semi-empirical Analysis of Complex ITC Data from Protein-Surfactant Interactions

    Tidemand, Frederik Grønbæk, Zunino, A., Johansen, Nicolai Tidemand, Hansen, A. F., Westh, P., Mosegaard, Klaus & Arleth, Lise, 21 Sep 2021, In: Analytical Chemistry. 93, 37, p. 12698-12706 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Probing solution structure of the pentameric ligand-gated ion channel GLIC by small-angle neutron scattering

    Lycksell, M., Rovsnik, U., Bergh, C., Johansen, Nicolai Tidemand, Martel, A., Porcar, L., Arleth, Lise, Howard, R. J. & Lindahl, E., 14 Sep 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 37, 9 p., 2108006118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Oligomerization of Pharmaceutically Relevant Insulin Analogues for Varying Concentration and Salinity Revealed by Small-Angle X-ray Scattering

    Jensen, G., Rosenmejer, K. R., Huda, P. & Arleth, Lise, 6 Sep 2021, In: Molecular Pharmaceutics. 18, 9, p. 3272-3280 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The microscopic distribution of hydrophilic polymers in interpenetrating polymer networks (IPNs) of medical grade silicone

    Smith, G. N., Brok, E., Schmiele, M., Mortensen, Kell, Bouwman, W. G., Duif, C. P., Hassenkam, Tue, Alm, M., Thomsen, P. & Arleth, Lise, 22 Mar 2021, In: Polymer. 224, 9 p., 123671.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Peptide discs as precursors of biologically relevant supported lipid bilayers

    Luchini, A., Sebastiani, Federica, Tidemand, Frederik Grønbæk, Batchu, K. C., Campana, M., Fragneto, G., Cárdenas, M. & Arleth, Lise, Mar 2021, In: Journal of Colloid and Interface Science. 585, p. 376-385 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Aescin - a natural soap for the formation of lipid nanodiscs with tunable size

    Geisler, R., Pedersen, Martin Cramer, Preisig, N., Hannappel, Y., Prevost, S., Dattani, R., Arleth, Lise & Hellweg, T., 21 Feb 2021, In: Soft Matter. 17, 7, p. 1888-1900 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Ab initio determination of the shape of membrane proteins in a nanodisc

    Orioli, S., Hansen, C. G. H. & Arleth, Lise, 2021, In: Acta crystallographica Section D: Structural biology . 77, p. 176-193 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects

    Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Lipid-bound ApoE3 self-assemble into elliptical disc-shaped particles

    Nørgrd Larsen, Andreas, Johansen, Nicolai Tidemand, Gajhede, Michael, Arleth, Lise & Midtgaard, S. R., 2021, In: B B A - Biomembranes. 1863, 1, 10 p., 183495.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Order and disorder - An integrative structure of the full-length human growth hormone receptor

    Kassem, N., Araya-Secchi, R., Bugge, K., Barclay, A., Steinocher, H., Khondker, A., Wang, Yong, Lenard, A. J., Bürck, J., Sahin, Cagla, Ulrich, A. S., Landreh, M., Pedersen, Martin Cramer, Rheinstädter, M. C., Pedersen, Per Amstrup, Lindorff-Larsen, Kresten, Arleth, Lise & Kragelund, Birthe Brandt, 2021, In: Science Advances. 7, 27, 20 p., eabh3805.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Properdin oligomers adopt rigid extended conformations supporting function

    Pedersen, D. V., Pedersen, M. N., Mazarakis, S. M. M., Wang, Yong, Lindorff-Larsen, Kresten, Arleth, Lise & Andersen, G. R., 2021, In: eLife. 10, 22 p., e63356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Solution Structure of the Gloeobacter Violaceus Ligand-Gated Ion Channel Probed by Small-Angle Neutron Scattering

    Lycksell, M., Rovsnik, U., Bergh, C. C., Johansen, Nicolai Tidemand, Martel, A., Porcar, L., Arleth, Lise, Howard, R. & Lindahl, E., 2021, In: Biophysical Journal. 120, 3, Supp. 1, p. 56a-56a 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Structural and Biophysical Properties of Supercharged and Circularized Nanodiscs

    Johansen, Nicolai Tidemand, Luchini, A., Tidemand, Frederik Grønbæk, Orioli, S., Martel, A., Porcar, L., Arleth, Lise & Pedersen, Martin Cramer, 2021, In: Langmuir. 37, 22, p. 6681-6690 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2020
  31. Published

    The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity

    Hendus-Altenburger, R., Vogensen, J., Pedersen, E. S., Luchini, A., Araya-Secchi, R., Bendsoe, A. H., Prasad, N. S., Prestel, Andreas, Cardenas, M., Pedraz-Cuesta, E., Arleth, Lise, Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 3 Dec 2020, In: Communications Biology . 3, 1, 18 p., 731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Assembly of Capsids from Hepatitis B Virus Core Protein Progresses through Highly Populated Intermediates in the Presence and Absence of RNA

    Oliver, R. C., Potrzebowski, W., Najibi, S. M., Pedersen, M. N., Arleth, Lise, Mahmoudi, N. & Andre, I., 25 Aug 2020, In: ACS Nano. 14, 8, p. 10226-10238 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Orchestration of signaling by structural disorder in class 1 cytokine receptors

    Seiffert, P., Bugge, K., Nygaard, M., Haxholm, G. W., Martinsen, J. H., Pedersen, M. N., Arleth, Lise, Boomsma, Wouter & Kragelund, Birthe Brandt, 24 Aug 2020, In: Cell Communication and Signaling. 18, 1, 30 p., 132.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Structural Insight into the Self-Assembly of a Pharmaceutically Optimized Insulin Analogue Obtained by Small-Angle X-ray Scattering

    Dreyer, L. S., Nygaard, J., Malik, L., Hoeg-Jensen, T., Hoiberg-Nielsen, R. & Arleth, Lise, 3 Aug 2020, In: Molecular Pharmaceutics. 17, 8, p. 2809-2820 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Assessment of structure factors for analysis of small-angle scattering data from desired or undesired aggregates

    Nørgrd Larsen, Andreas, Pedersen, J. S. & Arleth, Lise, Aug 2020, In: Journal of Applied Crystallography. 53, p. 991-1005 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations.

    Bengtsen, T., Midtgaard, S. R., Holm-Janas, Viktor, Kjølbye, L. R., Johansen, Nicolai Tidemand, Tesei, Giulio, Bottaro, S., Schiøtt, B., Arleth, Lise & Lindorff-Larsen, Kresten, 30 Jul 2020, In: eLife. 9, 24 p., e56518.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Protocol for Investigating the Interactions Between Intrinsically Disordered Proteins and Membranes by Neutron Reflectometry

    Luchini, A. & Arleth, Lise, 22 Jul 2020, Intrinsically Disordered Proteins: Methods and Protocols. Kragelund, B. B. & Skriver, K. (eds.). Humana Press, p. 569-584 16 p. (Methods in Molecular Biology, Vol. 2141).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  38. Published

    Dispersion state of TiO2 pigment particles studied by ultra-small-angle X-ray scattering revealing dependence on dispersant but limited change during drying of paint coating

    Lof, D., Hamieau, G., Zalich, M., Ducher, P., Kynde, S., Midtgaard, S. R., Parasida, C. F., Arleth, Lise & Jensen, G., 1 May 2020, In: Progress in Organic Coatings. 142, 8 p., 105590.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Exploring the Protein-Membrane Interactions on the Intracellular Side of PRLR

    Araya-Secchi, R., Bugge, K., Kragelund, Birthe Brandt & Arleth, Lise, 7 Feb 2020, In: Biophysical Journal. 118, 3, Suppl.1, p. 57A-57A 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  40. Published

    Small-angle Neutron Scattering Shows that the Solution Structures of the Bacterial Mg2+-Channel CorA are Overall Similar with and without Mg2+ Bound

    Arleth, Lise, Johansen, Nicolai Tidemand, Bengtsen, T., Larsen, A. H., Tidemand, Frederik Grønbæk, Pomorski, Thomas Guenther & Lindorff-Larsen, Kresten, 7 Feb 2020, In: Biophysical Journal. 118, 3, Suppl. 1, p. 12A 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  41. Published

    Supported Lipid Bilayers with Asymmetric Membrane Proteins: Controlling the Protein Orientation by using Peptide-Discs

    Luchini, A., Tidemand, Frederik Grønbæk, Araya-Secchi, R. R. & Arleth, Lise, 7 Feb 2020, In: Biophysical Journal. 118, 3, Suppl.1, p. 17A-17A 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  42. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution

    Nørgrd Larsen, Andreas, Wang, Yong, Bottaro, S., Grudinin, S., Arleth, Lise & Lindorff-Larsen, Kresten, 2020, In: P L o S Computational Biology. 16, 4, 29 p., e1007870.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer

    Tidemand, Frederik Grønbæk, Østergaard, H., Ploug, Michael, Kragelund, Birthe Brandt & Arleth, Lise, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 10 p., 183214.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. 2019
  46. Published

    Aescin-Induced Conversion of Gel-Phase Lipid Membranes into Bicelle-like Lipid Nanoparticles

    Geisler, R., Pedersen, Martin Cramer, Hannappel, Y., Schweins, R., Prevost, S., Dattani, R., Arleth, Lise & Hellweg, T., 10 Dec 2019, In: Langmuir. 35, 49, p. 16244-16255

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Distinct α-Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior

    Cholak, E., Bucciarelli, S., Bugge, K., Johansen, Nicolai Tidemand, Vestergaard, Bente, Arleth, Lise, Kragelund, Birthe Brandt & Langkilde, Annette Eva, Nov 2019, In: Biochemistry. 58, 50, p. 5052-5065

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Structure and Dynamics of the Central Lipid Pool and Proteins of the Bacterial Holo-Translocon

    Martin, R., Nørgrd Larsen, Andreas, Corey, R. A., Midtgaard, S. R., Frielinghaus, H., Schaffitzel, C., Arleth, Lise & Collinson, I., 21 May 2019, In: Biophysical Journal. 116, 10, p. 1931-1940 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Circularized and solubility-enhanced MSPs facilitate simple and high-yield production of stable nanodiscs for studies of membrane proteins in solution

    Johansen, Nicolai Tidemand, Tidemand, Frederik Grønbæk, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Pedersen, Martin Cramer & Arleth, Lise, May 2019, In: F E B S Journal. 286, 9, p. 1734-1751

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Probing Structural States of a Pentameric Ligand-Gated Ion Channel with Small Angle Neutron Scattering

    Lycksell, M., Johansen, Nicolai Tidemand, Howard, R. J., Arleth, Lise & Lindahl, E., 15 Feb 2019, In: Biophysical Journal. 116, 3, Supp. 1, p. 36A-37A

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Towards biomimics of cell membranes: Structural effect of phosphatidylinositol triphosphate (PIP3) on a lipid bilayer

    Luchini, A., Nzulumike, A. N. O., Lind, T. K., Nylander, T., Barker, R., Arleth, Lise, Mortensen, Kell & Cardenas, M., 1 Jan 2019, In: Colloids and Surfaces B: Biointerfaces. 173, p. 202-209

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    PSX, Protein-Solvent Exchange: software for calculation of deuterium-exchange effects in small-angle neutron scattering measurements from protein coordinates

    Pedersen, Martin Cramer, Wang, Yong, Tidemand, Frederik Grønbæk, Martel, A., Lindorff-Larsen, Kresten & Arleth, Lise, 2019, In: Journal of Applied Crystallography. 52, 6, p. 1427-1436 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Peptide disc mediated control of membrane protein orientation in supported lipid bilayers for surface-sensitive investigations

    Luchini, A., Tidemand, Frederik Grønbæk, Johansen, Nicolai Tidemand, Campana, M., Sotres, J., Ploug, Michael, Cárdenas, M. & Arleth, Lise, 2019, In: Analytical Chemistry. 92, 1, p. 1081-1088

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    SEC-SAXS on an in-house laboratory instrument

    Skou, S., Bucciarelli, S., Midtgaard, S. R., Pedersen, M. N., Arleth, Lise & Vestergaard, Bente, 2019, p. A230-A230. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  55. Published

    The influence of pH, protein concentration and calcium ratio on the formation and structure of nanotubes from partially hydrolyzed bovine α-lactalbumin

    Geng, X., Kirkensgaard, Jacob Judas Kain, Arleth, Lise, Otte, Jeanette & Ipsen, Richard, 2019, In: Soft Matter. 15, 24, p. 4787-4796

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. 2018
  57. Published

    Introducing SEC-SANS for studies of complex self-organized biological systems

    Johansen, Nicolai Tidemand, Pedersen, Martin Cramer, Porcar, L., Martel, A. & Arleth, Lise, 22 Dec 2018, In: Acta crystallographica Section D: Structural biology . 74, Part: 12, p. 1178-1191

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4240193