Lene Juel Rasmussen

Lene Juel Rasmussen

Managing director of centre, professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 1: Modifiable pathways of damage and repair in aging


  1. 2021
  2. Published

    Societal need for interdisciplinary ageing research

    Cherbuin, N., Lijima, K., Kalula, S., Malhotrad, R., Rasmussen, Lene Juel, Chan, A., Lafortune, L., Harper, S., Zheng, X., Lindeman, D., Walsh, E., Hussain, R., Burns, R., Kristiansen, Maria, Sugawara, I., Son, B., Tanaka, T., Buckner, S., Hoffman, J. & Combrinck, M., 25 Feb 2021, In : Biomedicine Hub. 6, 1, p. 42-47 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes

    Subramanian, V., Rodemoyer, B., Shastri, V., Rasmussen, Lene Juel, Madsen, Claus Desler & Schmidt, K. H., 2021, In : Scientific Reports. 11, 2157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    mHealth applications to support caregiver needs and engagement during stroke recovery: A content review

    Lobo, Elton Henry Savio, Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J. & Abdelrazek, M., 2021, In : Research in Nursing and Health. 44, 1, p. 213-225

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2020
  6. Published

    ARDD 2020: from aging mechanisms to interventions

    Mkrtchyan, Garik, Abdelmohsen, K., Andreux, P., Bagdonaite, Ieva , Barzilai, N., Brunak, Søren, Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J., Gorbunova, V., Grey, A. D., He, W. W., Hoeijmakers, J., Hoffmann, Eva, Horvath, S., Houtkooper, R. H., Jensen, Majken Karoline, Jensen, M. B., Kane, A., Kassem, M., Keizer, P. D., Kennedy, B., Karsenty, G., Lamming, D. W., Lee, K. F., MacAulay, Nanna, Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, Andreas, Niedernhofer, L., Osborne, Brenna, Pak, H. H., Parkhitko, A., Raimundo, N., Rando, T. A., Rasmussen, Lene Juel, Reis, C., Riedel, C. G., Franco-Romero, A., Schumacher, B., Sinclair, D. A., Suh, Y., Taub, P. R., Toiber, D., Treebak, Jonas Thue, Valenzano, D. R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2020, In : Aging. 12, 24, p. 24486-24503 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

    Møller, S. H., Mellergaard, Maiken, Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, Rikke Illum, Aldana Garcia, Blanca Irene, Madsen, Claus Desler, Rasmussen, Lene Juel, Sustarsic, Elahu Gosney, Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In : Frontiers in Immunology. 11, 22 p., 1968.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

    Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In : BMC Cancer. 20, 1, 14 p., 349.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

    Duan, Shunlei, Han, Xuerui, Akbari, Mansour, Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In : Nucleic Acids Research. 48, 12, p. 6530–6546

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions

    Bjerregaard, Victoria Alexandra, Schönewolf-Greulich, B., Rasmussen, Lene Juel, Madsen, Claus Desler & Tümer, Asuman Zeynep, 2020, In : Frontiers in Neurology. 11, 9 p., 163.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics

    du Mee, Dorine Jeanne Mariëtte, Bak, Mads, Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In : Mitochondrion. 53, p. 255-259

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Simvastatin improves mitochondrial respiration in peripheral blood cells

    Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Madsen, Claus Desler & Rasmussen, Lene Juel, 2020, In : Scientific Reports. 10, 1, 17012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

    Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Madsen, Claus Desler, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In : iScience. 23, 10, 42 p., 101556.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    TIP60 in aging and neurodegeneration

    Li, Zhiquan & Rasmussen, Lene Juel, 2020, In : Ageing Research Reviews. 64, 101195.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

    Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, Linda Hildegard, Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In : Mechanisms of Ageing and Development. 185, 111194.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome

    Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In : Genetics in Medicine. 22, p. 847–856

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2019
  18. Published

    A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis

    Hasan-Olive, M. M., Lauritzen, K. H., Ali, M., Rasmussen, Lene Juel, Storm-Mathisen, J. & Bergersen, Linda Hildegard, 2019, In : Neurochemical Research. 44, 1, p. 22-37 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome

    Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, Lene Juel, Greenblatt, M. S., de Wind, N. & Tavtigian, S. V., 2019, In : Genetics in Medicine. 21, p. 1486–1496

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    From powerhouse to perpetrator—mitochondria in health and disease

    Fakouri, N. B., Hansen, T. L., Madsen, Claus Desler, Anugula, Sharath & Rasmussen, Lene Juel, 2019, In : Biology. 8, 2, 15 p., 35.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    MERTK Acts as a costimulatory receptor on human cd8 t cells

    Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Madsen, Claus Desler & thor Straten, Per, 2019, In : Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Mitochondrial oxidative phosphorylation capacity of cryopreserved cells

    Lauridsen, P. E., Rasmussen, Lene Juel & Madsen, Claus Desler, 2019, In : Mitochondrion. 47, p. 47-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia

    Bundgaard, A., Qvortrup, Klaus, Rasmussen, Lene Juel & Fago, A., 2019, In : Journal of Experimental Biology. 222, 11, 9 p., jeb200410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2018
  25. Published

    Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus

    Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Madsen, Claus Desler, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, Linda Hildegard & Lauritzen, Martin, 2018, In : Neurobiology of Aging. 61, p. 215-224 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms

    Jakobsen, Emil, Lange, S. C., Andersen, Jens Velde, Madsen, Claus Desler, Kihl, H. F., Hohnholt, M., Stridh, M. H., Rasmussen, Lene Juel, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, 2018, In : Biochemical Pharmacology. 155, p. 92-101 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The role of mitochondrial dysfunction in the progression of Alzheimer’s disease

    Madsen, Claus Desler, Lillenes, M. S., Tønjum, T. & Rasmussen, Lene Juel, 2018, In : Current Medicinal Chemistry. 25, 40, p. 5578 - 5587

    Research output: Contribution to journalReviewResearchpeer-review

  28. 2017
  29. Published

    Bacterial infection increases risk of carcinogenesis by targeting mitochondria

    Strickertsson, J. A. B., Madsen, Claus Desler & Rasmussen, Lene Juel, Dec 2017, In : Seminars in Cancer Biology. 47, p. 95-100 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro

    Liu, D., Frederiksen, J. H., Liberti, S. E., Lützen, A., Keijzers, G., Pena-Diaz, J. & Rasmussen, Lene Juel, 19 Sep 2017, In : Nucleic Acids Research. 45, 16, p. 9427-9440 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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