Lena Specht

Lena Specht

Clinical Professor

Member of:

  • Clinical Oncology


  1. 2023
  2. Published

    A comparison of loco-regional relapse pattern in HPV positive vs negative oropharyngeal cancers following radiotherapy: relation to pretreatment FDG-PET and radiotherapy target volumes

    Håkansson, K., Lindegaard, A. M., Bernsdorf, M., Gothelf, A., Kristensen, C. A., Specht, Lena, Friborg, Jeppe Tang & Vogelius, Ivan R. , 2023, In: Acta Oncologica. 62, 9, p. 1028-1035 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A systematic review on clinical adaptive radiotherapy for head and neck cancer

    Lindegaard, A. M., Håkansson, K., Bernsdorf, M., Gothelf, A. B., Kristensen, C. A., Specht, Lena, Vogelius, Ivan R. & Friborg, Jeppe Tang, 2023, In: Acta oncologica (Stockholm, Sweden). 62, 11, p. 1360-1368 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Brentuximab Vedotin Plus AVD for First-Line Treatment of Early-Stage Unfavorable Hodgkin Lymphoma (BREACH): A Multicenter, Open-Label, Randomized, Phase II Trial

    Fornecker, L. M., Lazarovici, J., Aurer, I., Casasnovas, R. O., Gac, A. C., Bonnet, C., Bouabdallah, K., Feugier, P., Specht, L., Molina, L., Touati, M., Borel, C., Stamatoullas, A., Nicolas-Virelizier, E., Pascal, L., Lugtenburg, P., Di Renzo, N., Vander Borght, T., Traverse-Glehen, A., Dartigues, P. & 5 others, Hutchings, M., Versari, A., Meignan, M., Federico, M. & André, M., 2023, In: Journal of Clinical Oncology. 41, 2, p. 327-335 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Accepted/In press

    Career development: A balance of opportunities and choices

    de Jong, D., Kimby, E. & Specht, Lena, 2023, (Accepted/In press) In: Hematological Oncology. p. 1-4

    Research output: Contribution to journalComment/debateResearchpeer-review

  6. Published

    Increased incidence rates of positive blood cultures shortly after chemotherapy compared to radiotherapy among individuals treated for solid malignant tumours

    Roen, A., Terrones, C., Bannister, W., Helleberg, M., Andersen, M. A., Niemann, Carsten, Daugaard, G., Specht, Lena, Mocroft, A., Reekie, J. & Lundgren, Jens, 2023, In: Infection. 51, 11 p., 147–157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Accepted/In press

    Personalised therapy in follicular lymphoma – is the dial turning?

    Linton, K. M., Specht, Lena, Pavlovsky, A., Thompson, C. A., Kimby, E., de Jong, D., Nastoupil, L. J., Cottereau, A. S., Casulo, C., Sarkozy, C. & Okosun, J., 2023, (Accepted/In press) In: Hematological Oncology. 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Prediction of Radiation-induced Lymphopenia following Exposure of the Thoracic Region and Associated Risk of Infections and Mortality

    Terrones-Campos, C., Ledergerber, B., Forbes, N., Smith, Abraham George, Petersen, Jens, Helleberg, Marie, Lundgren, Jens, Specht, Lena & Vogelius, Ivan R. , 2023, In: Clinical Oncology. 35, 7, p. e434-e444 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Radiotherapy in Cutaneous Lymphomas and Cutaneous Sarcomas

    Specht, Lena & Coyle, C., 2023, Non-melanoma Skin Cancer: Essentials for Oncologists. Rembielak, A. & Tagliaferri, L. (eds.). CRC Press, p. 305-320 16 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  10. Published

    Reappraisal of the role of radiation therapy in lymphoma treatment

    Specht, Lena, 2023, In: Hematological Oncology. 41, S1, p. 75-81 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Systemic Treatment of Cutaneous Lymphomas

    Kamstrup, M. R. & Specht, Lena, 2023, Non-melanoma Skin Cancer: Essentials for Oncologists. Rembielak, A. & Tagliaferri, L. (eds.). CRC Press, p. 355-364 10 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. Published

    The potential for local ablative therapy of oligometastases in head and neck squamous cell carcinoma: a real-world data analysis

    Kjems, J., Laursen, M. R. T., Kristensen, C. A., Gothelf, A. B., Bernsdorf, M., Specht, Lena, Berthelsen, A. K., Vogelius, Ivan R. , Persson, Gitte F. & Friborg, Jeppe Tang, 2023, In: Acta Oncologica. 62, 9, p. 1091-1095

    Research output: Contribution to journalLetterResearchpeer-review

  13. 2022
  14. Published

    Early non-cancer mortality risk prediction after curative-intent radiotherapy or chemoradiotherapy for head and neck squamous cell carcinoma

    Jensen, K. H., Vogelius, Ivan R. , Bernsdorf, M., Gothelf, A., Kristensen, C. A., Maare, C., Andersen, E., Specht, Lena & Friborg, Jeppe Tang, Jun 2022, In: Radiotherapy and Oncology. 171, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A phase 2 trial of deep-inspiration breath hold in radiotherapy of gastric lymphomas

    Petersen, P. M., Rechner, L. A. & Specht, Lena, Apr 2022, In: Physics & imaging in radiation oncology. 22, p. 137-141 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Hyperbaric oxygen treatment of mandibular osteoradionecrosis: Combined data from the two randomized clinical trials DAHANCA-21 and NWHHT2009-1

    Forner, L. E., Dieleman, F. J., Shaw, R. J., Kanatas, A., Butterworth, C. J., Kjeller, G., Alsner, J., Overgaard, J., Hillerup, S., Hyldegaard, Ole, Arnell, P., von Buchwald, Christian, Kaanders, J. H. A. M., Smeele, L. E., Specht, Lena, Johansen, J., Witjes, M. J. H., Merkx, M. A. W. & Jansen, E. C., Jan 2022, In: Radiotherapy and Oncology. 166, p. 137-144 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Baseline FDG PET/CT in free breathing versus deep inspiration breath-hold for pediatric patients with mediastinal lymphoma

    Lundgaard, A. Y., Dejanovic, D., Berthelsen, A. K., Andersen, Flemming Littrup, Rechner, L. A., Borgwardt, L., Hjalgrim, L. L., Specht, Lena & Maraldo, M. V., 2022, In: Acta Oncologica. 61, 2, p. 239-246 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Cardiovascular risk factors, radiation therapy, and myocardial infarction among lymphoma survivors

    Salz, T., Zabor, E. C., Brown, Peter de Nully, Dalton, Susanne Oksbjerg, Raghunathan, N. J., Matasar, M. J., Steingart, R., Hjalgrim, Henrik, Specht, Lena, Vickers, A. J., Oeffinger, K. C. & Johansen, Christoffer, 2022, In: Acta Oncologica. 61, 9, p. 1064-1068

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Intraglandular Off-the-Shelf Allogeneic Mesenchymal Stem Cell Treatment in Patients with Radiation-Induced Xerostomia: A Safety Study (MESRIX-II)

    Lynggaard, C. D., Grønhøj, Christian, Christensen, R., Fischer-Nielsen, A., Melchiors, Jacob, Specht, Lena, Andersen, E., Mortensen, Jann, Oturai, P., Barfod, G. H., Haastrup, E. K., Møller-Hansen, M., Haack-Sørensen, M., Ekblond, A., Kastrup, J., Jensen, S. B. & von Buchwald, Christian, 2022, In: Stem Cells Translational Medicine. 11, 5, p. 478-489 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Long-term Safety of Treatment with Autologous Mesenchymal Stem Cells in Patients with Radiation-Induced Xerostomia: Primary Results of the MESRIX Phase I/II Randomized Trial

    Lynggaard, C. D., Grønhøj, Christian, Jensen, S. B., Christensen, R., Specht, Lena, Andersen, E., Andersen, T. T., Ciochon, U. M., Rathje, G. S., Hansen, Adam Espe, Stampe, H., Fischer-Nielsen, A. & von Buchwald, Christian, 2022, In: Clinical Cancer Research. 28, 13, p. 2-2897 2896 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    PET for radiotherapy planning

    Dejanovic, D., Specht, Lena, Munk, O. L., Christensen, C. B., Berthelsen, A. K., Law, Ian & Loft, A., 2022, Nuclear Medicine and Molecular Imaging: Volume 1-4. Elsevier, Vol. 3. p. 774-792 19 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    PET/CT til radioterapi

    Specht, Lena, Berthelsen, A. K. & Jakobsen, A. L., 2022, Klinisk Nuklearmedicin. Munksgaard , p. 266-272

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  23. Published

    Patterns of relapse and long-term outcome in patients treated with a curative intent for advanced Hodgkin lymphoma

    Nielsen, K., Maraldo, M. V., Berthelsen, A. K., Loft, A., Brown, Peter de Nully, Vogelius, I. R., Petersen, P. M. & Specht, Lena, 2022, In: Acta Oncologica. 61, 9, p. 1056-1063 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Response Evaluation Following Radiation Therapy With 18F-FDG PET/CT: Common Variants of Radiation-Induced Changes and Potential Pitfalls

    Dejanovic, D., Specht, Lena, Czyzewska, D., Kiil Berthelsen, A. & Loft, A., 2022, In: Seminars in Nuclear Medicine. 52, 6, p. 681-706 26 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Risk of Bacterial, Viral, and Fungal Infections in Patients With Solid Malignant Tumors Treated With Curative Intent Radiation Therapy

    Terrones-Campos, C., Ledergerber, B., Specht, Lena, Vogelius, Ivan R. , Helleberg, M. & Lundgren, Jens, 2022, In: Advances in Radiation Oncology. 7, 6, 16 p., 100950.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    RootPainter3D: Interactive-machine-learning enables rapid and accurate contouring for radiotherapy

    Smith, Abraham George, Petersen, Jens, Terrones-Campos, C., Berthelsen, A. K., Forbes, N. J., Darkner, Sune, Specht, Lena & Vogelius, I. R., 2022, In: Medical Physics. 49, 1, p. 461-473

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2021
  28. Published

    Intratumor heterogeneity is biomarker specific and challenges the association with heterogeneity in multimodal functional imaging in head and neck squamous cell carcinoma

    Rasmussen, J. H., Olin, A. B., Lelkaitis, G., Hansen, Adam Espe, Andersen, Flemming Littrup, Johannesen, H. H., Kjær, Andreas, Fischer, Barbara Malene Bjerregaard, Specht, Lena, Bentzen, S. M., von Buchwald, Christian, Wessel, Irene & Vogelius, Ivan R. , Jun 2021, In: European Journal of Radiology. 139, 8 p., 109668.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Hematological toxicity in patients with solid malignant tumors treated with radiation – Temporal analysis, dose response and impact on survival

    Terrones-Campos, C., Ledergerber, B., Vogelius, I. R., Helleberg, M., Specht, Lena & Lundgren, Jens, May 2021, In: Radiotherapy and Oncology. 158, p. 175-183 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Iatrogenic cerebral radiation necrosis

    Hilton, C. M. H., Specht, Lena, Lund, Eva Løbner, Martens, P. C., Schmidt, G. & Krarup, L. H., 2021, In: Practical Neurology. 21, 5, p. 427-430 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Lymphoma: advances in imaging and radiotherapy – introductory editorial

    Illidge, T., Mikhaeel, N. G., Specht, Lena & Yahalom, J., 2021, In: British Journal of Radiology. 94, 1127, 2 p., 20219005.

    Research output: Contribution to journalEditorialResearchpeer-review

  32. Published

    Modern Radiation Therapy for Extranodal Nasal-Type NK/T-cell Lymphoma: Risk-Adapted Therapy, Target Volume, and Dose Guidelines from the International Lymphoma Radiation Oncology Group

    Qi, S. N., Li, Y. X., Specht, Lena, Oguchi, M., Tsang, R., Ng, A., Suh, C. O., Ricardi, U., Mac Manus, M., Dabaja, B. & Yahalom, J., 2021, In: International Journal of Radiation Oncology Biology Physics. 110, 4, p. 1064-1081

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    No changes in myocardial perfusion following radiation therapy of left-sided breast cancer: A positron emission tomography study

    Rasmussen, T., Kjær, Andreas, Lassen, M. L., Pedersen, A. N., Specht, Lena, Aznar, M. C. & Hasbak, P., 2021, In: Journal of Nuclear Cardiology. 28, p. 1923–1932 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Outcome-based multiobjective optimization of lymphoma radiation therapy plans

    Modiri, A., Vogelius, Ivan R. , Ann Rechner, L., Nygård, L., Bentzen, S. M. & Specht, Lena, 2021, In: British Journal of Radiology. 94, 1127, 20210303.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Prevalence of cognitive impairment and its relation to mental health in Danish lymphoma survivors

    Mariegaard, J., Wenstrup, J., Lim, K. Z. M., Bidstrup, Pernille Envold Hansen, von Heymann, A., Johansen, Christoffer, Knudsen, Gitte Moos, Law, Ian, Specht, Lena & Stenbæk, Dea Siggaard, 2021, In: Supportive Care in Cancer. 29, p. 3319–3328 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Relapse localization in Danish pediatric patients with Hodgkin lymphoma

    Lundgaard, A. Y., Hjalgrim, L. L., Dejanovic, D., Berthelsen, A. K., Schomerus, E., Wendtland, P., Specht, Lena & Maraldo, M. V., 2021, In: Acta Oncologica. 60, 5, p. 658-666 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Robustness and Generalizability of Deep Learning Synthetic Computed Tomography for Positron Emission Tomography/Magnetic Resonance Imaging–Based Radiation Therapy Planning of Patients With Head and Neck Cancer

    Olin, A. B., Thomas, C., Hansen, Adam Espe, Rasmussen, J. H., Krokos, G., Urbano, T. G., Michaelidou, A., Jakoby, B., Ladefoged, C. N., Berthelsen, A. K., Håkansson, K., Vogelius, Ivan R. , Specht, Lena, Barrington, S. F., Andersen, Flemming Littrup & Fischer, Barbara Malene Bjerregaard, 2021, In: Advances in Radiation Oncology. 6, 6, 100762.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The risk of late effects following pediatric and adult radiotherapy regimens in Hodgkin lymphoma

    Lundgaard, A. Y., Hjalgrim, L. L., Rechner, L. A., Lundemann, M., Brodin, N. P., Joergensen, M., Specht, Lena & Maraldo, M. V., 2021, In: Strahlentherapie und Onkologie. 197, p. 711–721

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Total Body Irradiation in Haematopoietic Stem Cell Transplantation for Paediatric Acute Lymphoblastic Leukaemia: Review of the Literature and Future Directions

    Hoeben, B. A. W., Wong, J. Y. C., Fog, L. S., Losert, C., Filippi, A. R., Bentzen, S. M., Balduzzi, A. & Specht, Lena, 2021, In: Frontiers in Pediatrics. 9, 28 p., 774348.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Total tumor burden in lymphoma – an evolving strong prognostic parameter

    Meignan, M., Cottereau, A. S., Specht, Lena & Mikhaeel, N. G., 2021, In: British Journal of Radiology. 94, 1127, 9 p., 20210448.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2020
  42. Published

    Impact of p16-overexpression on overall and progression-free survival outcomes in oral cavity squamous cell carcinomas: A semi-national, population-based study

    Schneider, K., Jakobsen, K. K., Jensen, J. S., Wessel, Irene , Christensen, Anders, Specht, Lena, Lelkaitis, G., Mirian, C., Buchwald, C. V. & Grønhøj, C., 1 Dec 2020, In: Oral Oncology. 111, 5 p., 105031.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    In Reply to Scarpelli et al

    Specht, Lena, Wong, J. Y. C., Filippi, A. R., Dabaja, B. S. & Yahalom, J., 1 Dec 2020, In: International Journal of Radiation Oncology, Biology, Physics. 108, 5, p. 1396 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  44. Published

    Involved node radiation therapy in the combined modality treatment for early-stage Hodgkin lymphoma: Analysis of relapse location and long-term outcome

    Nielsen, K., Maraldo, M. V., Berthelsen, A. K., Loft, A., Brown, Peter de Nully, Vogelius, Ivan R. , Petersen, P. M. & Specht, Lena, 1 Sep 2020, In: Radiotherapy and Oncology. 150, p. 236-244 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Does multiparametric imaging with 18F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?

    Rasmussen, J. H., Olin, A., Lelkaitis, G., Hansen, Adam Espe, Andersen, Flemming Littrup, Johannesen, H. H., Kjær, Andreas, Vogelius, Ivan R. , Specht, Lena, Bentzen, S. M., Wessel, I., von Buchwald, Christian & Fischer, Barbara Malene Bjerregaard, Jul 2020, In: British Journal of Cancer. 123, 1, p. 46-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Mortality and admission to intensive care units after febrile neutropenia in patients with cancer

    Aagaard, T., Reekie, J., Jørgensen, M., Roen, A., Daugaard, G., Specht, Lena, Sengeløv, Henrik, Mocroft, A., Lundgren, Jens & Helleberg, M., May 2020, In: Cancer Medicine. 9, 9, p. 3033-3042 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Biological optimization for mediastinal lymphoma radiotherapy - a preliminary study

    Rechner, L. A., Modiri, A., Stick, L. B., Maraldo, M. V., Aznar, M. C., Rice, S. R., Sawant, A., Bentzen, S. M., Vogelius, Ivan R. & Specht, Lena, 27 Mar 2020, In: Acta Oncologica. 59, 8, p. 879-887 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Development and validation of a cycle-specific risk score for febrile neutropenia during chemotherapy cycles 2-6 in patients with solid cancers: The CSRFENCE score

    Aagaard, T., Reekie, J., Roen, A., Daugaard, G., Specht, Lena, Sengeløv, Henrik, Mocroft, A., Lundgren, Jens & Helleberg, M., 15 Jan 2020, In: International Journal of Cancer. 146, 2, p. 321-328 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Cardiac Lymphoma, a Challenging Extranodal Lymphoma

    Specht, Lena, 2020, In: International Journal of Radiation Oncology Biology Physics. 106, 3, 1 p.

    Research output: Contribution to journalLetterResearchpeer-review

  50. Published

    Early-stage mantle cell lymphoma—a rare entity with special characteristics and needs for treatment

    Specht, Lena & on behalf of the International Lymphoma Radiation Oncology Group (ILROG), O. B. O. T. I. L. R. O. G. (., 2020, In: Annals of Hematology. 99, 12, p. 2963-2964

    Research output: Contribution to journalComment/debateResearch

  51. Published

    Extranodal NK/T-cell lymphoma, nasal type, with extranasal presentation–a case report and a review of the literature

    Akbar, M., Clasen-Linde, E. & Specht, Lena, 2020, In: Acta Oncologica. p. 1-8 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    Feasibility of Multiparametric Positron Emission Tomography/Magnetic Resonance Imaging as a One-Stop Shop for Radiation Therapy Planning for Patients with Head and Neck Cancer

    Olin, A. B., Hansen, Adam Espe, Rasmussen, J. H., Ladefoged, C. N., Berthelsen, A. K., Håkansson, K., Vogelius, Ivan R. , Specht, Lena, Gothelf, A. B., Kjær, Andreas, Fischer, Barbara Malene Bjerregaard & Andersen, Flemming Littrup, 2020, In: International Journal of Radiation Oncology Biology Physics. 108, 5, p. 1329-1338 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    ILROG Lymphoma Mini-Atlas Part II, Hodgkin Lymphoma

    Dabaja, B. S., Ng, A. K., Terezakis, S. A., Plastaras, J. P., Yunes, M., Wilson, L. D., Yang, J., Gunther, J. R., Specht, Lena & Yahalom, J., 2020, In: International Journal of Radiation Oncology Biology Physics. 108, 4, p. 977-978

    Research output: Contribution to journalEditorialResearchpeer-review

  54. Published

    ILROG emergency guidelines for radiation therapy of hematological malignancies during the COVID-19 pandemic

    Yahalom, J., Dabaja, B. S., Ricardi, U., Ng, A., Mikhaeel, N. G., Vogelius, Ivan R. , Illidge, T., Qi, S., Wirth, A. & Specht, Lena, 2020, In: Blood. 135, 21, p. 1829-1832 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Involved Site Radiation Therapy in Adult Lymphomas: An Overview of International Lymphoma Radiation Oncology Group Guidelines

    Wirth, A., Mikhaeel, N. G., Aleman, B. M. P., Pinnix, C. C., Constine, L. S., Ricardi, U., Illidge, T. M., Eich, H. T., Hoppe, B. S., Dabaja, B., Ng, A. K., Kirova, Y., Berthelsen, A. K., Dieckmann, K., Yahalom, J. & Specht, Lena, 2020, In: International Journal of Radiation Oncology Biology Physics. 107, 5, p. 909-933 25 p.

    Research output: Contribution to journalReviewResearchpeer-review

  56. Published

    Making Every Single Gray Count: Involved Site Radiation Therapy Delineation Guidelines for Hematological Malignancies

    Dabaja, B. S., Ng, A. K., Terezakis, S. A., Plastaras, J. P., Yunes, M., Wilson, L. D., Specht, Lena & Yahalom, J., 2020, In: International Journal of Radiation Oncology Biology Physics. 106, 2, p. 279-281 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  57. Published

    Outcome in patients with isolated regional recurrence after primary radiotherapy for head and neck cancer

    Lindegaard, A. M., von Buchwald, Christian, Rasmussen, J. H., Specht, Lena, Vogelius, Ivan R. , Zamani, M., Woller, N. C., Lelkaitis, G. & Friborg, Jeppe Tang, 2020, In: Head and Neck. 42, 11, p. 3161-3170

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Primary prophylaxis with G-CSF may improve outcomes in patients with newly diagnosed stage III/IV Hodgkin lymphoma treated with brentuximab vedotin plus chemotherapy

    Straus, D., Collins, G., Walewski, J., Zinzani, P. L., Grigg, A., Sureda, A., Illes, A., Kim, T. M., Alekseev, S., Specht, Lena, Buccheri, V., Younes, A., Connors, J., Forero-Torres, A., Fenton, K., Gautam, A., Purevjal, I., Liu, R. & Gallamini, A., 2020, In: Leukemia and Lymphoma. 61, 12, p. 2931-2938 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Radiation dose-painting with protons vs. photons for head-and-neck cancer

    Håkansson, K., Smulders, B., Specht, Lena, Zhu, M., Friborg, Jeppe Tang, Rasmussen, J. H., Bentzen, S. M. & Vogelius, I. R., 2020, In: Acta Oncologica. 59, 5, p. 525-533

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Randomized phase II study with cetuximab in combination with 5-FU and cisplatin or carboplatin vs. cetuximab in combination with paclitaxel and carboplatin for treatment of patients with relapsed or metastatic squamous cell carcinoma of the head and neck (cetmet trial)

    Tsakonas, G., Specht, Lena, Kristensen, C. A., Moreno, M. H. C., Cange, H. H., Soderstrom, K. & Friesland, S., 2020, In: Cancers. 12, 11, p. 1-11 11 p., 3110.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Relapse-localization in pediatric patients with Hodgkin lymphoma

    Lundgaard, C. A. Y., Hjalgrim, L. L., Berthelsen, A. K., Specht, Lena, Borgwardt, L. & Maraldo, M., 2020, In: Klinische Padiatrie. 232, 2, p. 106-106 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  62. Published

    Risk factors for cardiovascular disease in 5-year survivors of adolescent and young adult cancer: A Danish population-based cohort study

    Licht, S. D. F., Maraldo, M. V., Specht, Lena, Nielsen, T. T., Winther, J. F. & Rugbjerg, K., 2020, In: Cancer. 126, 3, p. 659-669

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Stage I-II nodular lymphocyte-predominant Hodgkin lymphoma: A multi-institutional study of adult patients by ILROG

    Binkley, M. S., Shahzad Rauf, M., Milgrom, S. A., Pinnix, C. C., Tsang, R., Dickinson, M., Ng, A. K., Roberts, K. B., Gao, S., Balogh, A., Ricardi, U., Levis, M., Casulo, C., Stolten, M., Specht, L., Plastaras, J. P., Wright, C., Kelsey, C. R., Brady, J. L., George Mikhaeel, N. & 17 others, Hoppe, B. S., Terezakis, S. A., Picardi, M., Pepa, R. D., Kirova, Y., Akhtar, S., Maghfoor, I., Koenig, J. L., Jackson, C., Song, E., Sehgal, S., Advani, R. H., Natkunam, Y., Constine, L. S., Eich, H. T., Wirth, A. & Hoppe, R. T., 2020, In: Blood. 135, 26, p. 2365-2374 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The Feasibility of Implementing Deep Inspiration Breath-Hold for Pediatric Radiation Therapy

    Lundgaard, A. Y., Josipovic, M., Rechner, L. A., Bidstrup, Pernille Envold Hansen, Hansen, R., Damkjaer, S. S., Joergensen, M., Safwat, A., Specht, Lena, Hjalgrim, L. L. & Maraldo, M. V., 2020, In: International Journal of Radiation Oncology Biology Physics. 106, 5, p. 977-984

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 2019
  66. Published

    The Optimal Use of Imaging in Radiation Therapy for Lymphoma: Guidelines from the International Lymphoma Radiation Oncology Group (ILROG)

    Mikhaeel, N. G., Milgrom, S. A., Terezakis, S., Berthelsen, A. K., Hodgson, D., Eich, H. T., Dieckmann, K., Qi, S. N., Yahalom, J. & Specht, Lena, Jul 2019, In: International Journal of Radiation Oncology Biology Physics. 104, 3, p. 501-512

    Research output: Contribution to journalReviewResearchpeer-review

  67. Published

    Intratumor heterogeneity of PD-L1 expression in head and neck squamous cell carcinoma

    Rasmussen, J. H., Lelkaitis, G., Håkansson, K., Vogelius, I. R., Johannesen, H. H., Fischer, B. M., Bentzen, S. M., Specht, Lena, Kristensen, C. A., von Buchwald, Christian, Wessel, Irene & Friborg, Jeppe Tang, 14 May 2019, In: British Journal of Cancer. 120, p. 1003-1006

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Preparing data for multiparametric PET/MR imaging: Influence of PET point spread function modelling and EPI distortion correction on the spatial correlation of [18F]FDG-PET and diffusion-weighted MRI in head and neck cancer

    Olin, A., Krogager, L., Rasmussen, J. H., Andersen, F. L., Specht, Lena, Beyer, T., Kjaer, A., Fischer, B. M. & Hansen, A. E., May 2019, In: Physica Medica. 61, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    A step and shoot intensity modulated technique for total body irradiation

    Fog, L. S., Hansen, V. N., Kjær-kristoffersen, F., Berlon, T. E., Petersen, P. M., Mandeville, H. & Specht, Lena, 2019, In: Technical Innovations & Patient Support in Radiation Oncology. 10, p. 1-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    CBCT is not valid for response evaluation after chemoradiotherapy for locally advanced NSCLC

    Persson, Gitte F., Pohl, M., Nygard, L., De Blanck, S. R., Scherman, J., Langer, Seppo W., Larsen, Klaus Richter, Clementsen, P. F., Specht, Lena, Fischer, Barbara Malene Bjerregaard, Aznar, M. C. & Josipovic, Mirjana, 2019, In: Radiotherapy & Oncology. 133, S1, p. S398-S399 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  71. Published

    Cutaneous Lymphomas

    Specht, Lena & Skov, L., 2019, In: Clinical Oncology. 31, 11, p. 797-807 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Deep inspiration breath hold in locally advanced lung cancer radiotherapy: validation of intrafractional geometric uncertainties in the INHALE trial

    Josipovic, Mirjana, Aznar, M. C., Thomsen, J. B., Scherman, J., Damkjaer, S., Nygard, L., Specht, Lena, Pohl, M. & Persson, Gitte F., 2019, In: British Journal of Radiology. 92, 1104, 10 p., 20190569.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Incidence and survival of hypopharyngeal cancer: a Danish Nation-Wide Study from 1980 to 2014

    Jakobsen, K. K., Wingstrand, V. L., Jensen, J. S., Grønhøj, C., Jensen, D. H., Karnov, K., Agander, T. K., Specht, Lena & von Buchwald, Christian, 2019, In: Acta Oncologica. 58, 11, p. 1570-1576 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Incidence and survival of laryngeal cancer in Denmark: a nation-wide study from 1980 to 2014

    Nahavandipour, A., Jakobsen, K. K., Grønhøj, C., Hebbelstrup Jensen, D., Kim Schmidt Karnov, K., Klitmøller Agander, T., Specht, Lena & von Buchwald, Christian, 2019, In: Acta Oncologica. 58, 7, p. 977-982 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Less mucositis toxicity after 6 versus 3 fractions of high-dose total body irradiation before allogeneic stem cell transplantation

    Sengeløv, Henrik, Petersen, P. M., Fog, L., Schmidt, M. & Specht, Lena, 2019, In: Bone Marrow Transplantation. 54, 8, p. 1369-1371 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Lymphocyte Count Kinetics, Factors Associated with the End-of-Radiation-Therapy Lymphocyte Count, and Risk of Infection in Patients with Solid Malignant Tumors Treated with Curative-Intent Radiation Therapy

    Terrones-Campos, C., Ledergerber, B., Vogelius, Ivan R. , Specht, Lena, Helleberg, M. & Lundgren, Jens, 2019, In: International Journal of Radiation Oncology Biology Physics. 105, 4, p. 812-823

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    On the relation between improved loco-regional control and disease-free survival in head-and-neck cancer

    Håkansson, K., Rasmussen, J. H., Bentzen, S. M., Friborg, Jeppe Tang, Specht, Lena & Vogelius, Ivan R. , 2019, In: Acta Oncologica. 58, 3, p. 390-392 3 p.

    Research output: Contribution to journalComment/debateResearch

  78. Published

    The Copenhagen Oral Cavity Squamous Cell Carcinoma database: protocol and report on establishing a comprehensive oral cavity cancer database

    Schmidt Jensen, J., Jakobsen, K. K., Mirian, C., Christensen, J. T., Schneider, K., Nahavandipour, A., Wingstrand, V. L., Wessel, Irene , Tvedskov, Jesper Filtenborg, Frisch, T., Christensen, A., Specht, Lena, Andersen, E., Lelkaitis, G., Grønhøj, C. & von Buchwald, Christian, 2019, In: Clinical Epidemiology. 11, p. 733-741

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. 2018
  80. Published

    Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer

    de Blanck, S. R., Rydhog, J. S., Larsen, Klaus Richter, Clementsen, P. F., Josipovic, Mirjana, Aznar, M. C., af Rosenschold, P. M., Jolck, R. I., Specht, Lena, Andresen, T. L. & Persson, Gitte F., 3 Nov 2018, In: Clinical and Translational Radiation Oncology. 13, p. 24-28

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Feasibility of a novel liquid fiducial marker for use in image guided radiotherapy of oesophageal cancer

    De Blanck, S. R., Scherman-Rydhog, J., Siemsen, Mette, Christensen, M., Baeksgaard, L., Jolck, R. I., Specht, Lena, Andresen, T. L. & Persson, Gitte F., 9 Jul 2018, In: British Journal of Radiology. 91, 1092, 5 p., 20180236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Safety and Efficacy of Mesenchymal Stem Cells for Radiation-Induced Xerostomia: A Randomized, Placebo-Controlled Phase 1/2 Trial (MESRIX)

    Grønhøj, C., Jensen, D. H., Vester-Glowinski, Peter Viktor, Jensen, S. B., Bardow, A., Oliveri, R. S., Fog, L. M., Specht, Lena, Thomsen, C., Darkner, Sune, Jensen, M., Müller, V., Kiss, K., Agander, T., Andersen, E., Fischer-Nielsen, A. & von Buchwald, Christian, 1 Jul 2018, In: International Journal of Radiation Oncology, Biology, Physics. 101, 3, p. 581-592 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Coplanar and non-coplanar VMAT facilitate OAR dose sparing in central lung SBRT

    Thomsen, J. B., Persson, Gitte F., Aznar, M. C., Berthelsen, A. K., Specht, Lena & Josipovic, Mirjana, 20 Apr 2018, In: Radiotherapy & Oncology. 127, Supp.1, p. S1021-S1021 EP-1886.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  84. Published

    A clinical prognostic model compared to the newly adopted UICC staging in an independent validation cohort of P16 negative/positive head and neck cancer patients

    Rasmussen, J. H., Håkansson, K., Rasmussen, G. B., Vogelius, Ivan R. , Friborg, J., Fischer, Barbara Malene Bjerregaard, Bentzen, S. M. & Specht, Lena, 2018, In: Oral Oncology. 81, p. 52-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    An extended hypofractionated palliative radiotherapy regimen for head and neck carcinomas

    Laursen, M., Specht, Lena, Kristensen, C. A., Gothelf, A., Bernsdorf, M., Vogelius, Ivan R. & Friborg, J., 2018, In: Frontiers in Oncology. 8, JUN, 8 p., 206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    DAHANCA 10: Effect of darbepoetin alfa and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. A multicenter, open-label, randomized, phase 3 trial by the Danish head and neck cancer group

    Overgaard, J., Hoff, C. M., Hansen, H. S., Specht, Lena, Overgaard, M., Lassen, P., Andersen, E., Johansen, J., Andersen, L. J., Evensen, J. F., Alsner, J. & Grau, C., 2018, In: Radiotherapy & Oncology. 127, 1, p. 12-19

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Deep inspiration breath hold and locally advanced lung cancer: validation of geometrical uncertainties

    Josipovic, M., Aznar, M., Damkjær, S., Thomsen, J., Rydhög, J., Nygård, L., Specht, Lena, Pøhl, M. & Persson, Gitte F., 2018, In: Radiotherapy and Oncology. 127, Supplement 1, p. S1102-S1103 EP-2020.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  88. Published

    Deep sequencing of human papillomavirus positive loco-regionally advanced oropharyngeal squamous cell carcinomas reveals novel mutational signature

    Grønhøj, C., Jensen, D. H., Agander, T., Kiss, K., Høgdall, Estrid Vilma Solyom, Specht, Lena, Bagger, F. O., Nielsen, Finn Cilius & von Buchwald, Christian, 2018, In: BMC Cancer. 18, 1, p. 1-10 10 p., 640.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Impact of Time to Treatment Initiation in Patients with Human Papillomavirus-positive and -negative Oropharyngeal Squamous Cell Carcinoma

    Grønhøj, C., Jensen, D., Dehlendorff, C., Nørregaard, C., Andersen, E., Specht, Lena, Charabi, Birgitte Wittenborg & von Buchwald, Christian, 2018, In: Clinical Oncology. 30, 6, p. 375-381 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Incidence and survival in sinonasal carcinoma: a Danish population-based, nationwide study from 1980 to 2014

    Sjöstedt, S., Jensen, D. H., Jakobsen, K. K., Grønhøj, C., Geneser, C., Karnov, K., Specht, Lena, Agander, T. K. & von Buchwald, Christian, 2018, In: Acta Oncologica. 57, 9, p. 1152-1158 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Incidence and survival of oropharyngeal cancer in Denmark: a nation-wide, population-based study from 1980 to 2014

    Jensen, J. S., Jensen, D. H., Grønhøj, C., Karnov, K. K. S., Nørregaard, C., Agander, T. K., Specht, Lena & von Buchwald, Christian, 2018, In: Acta Oncologica. 57, 2, p. 269-275

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Increasing incidence and survival of head and neck cancers in Denmark: a nation-wide study from 1980 to 2014

    Jakobsen, K. K., Grønhøj, C., Jensen, D. H., Karnov, K. K. S., Agander, T. K., Specht, Lena & von Buchwald, Christian, 2018, In: Acta Oncologica. 57, 9, p. 1143-1151 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Lymphoblastic Lymphoma: Guidelines From the International Lymphoma Radiation Oncology Group (ILROG)

    Dabaja, B. S., Specht, Lena & Yahalom, J., 2018, In: International Journal of Radiation Oncology, Biology, Physics. 102, 3, p. 508-514 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  94. Published

    MA05.06 Locally Advanced Lung Cancer Radiotherapy in Deep Inspiration Breath Hold: Dosimetric Benefits from a Prospective Trial

    Josipovic, M., Aznar, M., Rydhög, J., Thomsen, J., Damkjaer, S., Nygård, L., Pøhl, M., Langer, S., Specht, Lena & Persson, Gitte F., 2018, In: Journal of Thoracic Oncology. 13, 10, suppl., p. S372-S373

    Research output: Contribution to journalConference abstract in journalResearch

  95. Published

    Metal artefact reduction for accurate tumour delineation in radiotherapy

    Kovacs, D. G., Rechner, L. A., Appelt, A. L., Berthelsen, A. K., Costa, J. C., Friborg, J., Persson, Gitte F., Bangsgaard, J. P., Specht, Lena & Aznar, M. C., 2018, In: Radiotherapy and Oncology. 126, 3, p. 479-486

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    MicroRNA-based classifiers for diagnosis of oral cavity squamous cell carcinoma in tissue and plasma

    Pedersen, N. J., Jensen, D. H., Lelkaitis, G., Kiss, K., Charabi, Birgitte Wittenborg, Ullum, H., Specht, Lena, Schmidt, A. Y., Nielsen, Finn Cilius & von Buchwald, Christian, 2018, In: Oral Oncology. 83, p. 46-52

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    PET/CT in Radiation Therapy Planning

    Specht, Lena & Berthelsen, A. K., 2018, In: Seminars in Nuclear Medicine. 48, 1, p. 67-75

    Research output: Contribution to journalReviewResearchpeer-review

  98. Published

    Patterns of relapse in patients with early stage Hodgkin lymphoma treated in the modern era

    Nielsen, K., Maraldo, M. V., Berthelsen, A. K., Jakobsen, A. L., Petersen, P. M., Aznar, M. C., Vogelius, Ivan R. , Brown, Peter de Nully & Specht, Lena, 2018, In: Radiotherapy and Oncology. 127, Supplement 1, p. S376-S377 PO-0736.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  99. Published

    Primary cutaneous lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

    ESMO Guidelines Committee, E. G. C., 2018, In: Annals of oncology : official journal of the European Society for Medical Oncology. 29, Supplement 4, p. iv30-iv40

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Proton therapy for adults with mediastinal lymphomas: the International Lymphoma Radiation Oncology Group guidelines

    Dabaja, B. S., Hoppe, B. S., Plastaras, J. P., Newhauser, W., Rosolova, K., Flampouri, S., Mohan, R., Mikhaeel, N. G., Kirova, Y., Specht, Lena & Yahalom, J., 2018, In: Blood. 132, 16, p. 1635-1646 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  101. Published

    Radiation Therapy for Solitary Plasmacytoma and Multiple Myeloma: Guidelines From the International Lymphoma Radiation Oncology Group

    Tsang, R. W., Campbell, B. A., Goda, J. S., Kelsey, C. R., Kirova, Y. M., Parikh, R. R., Ng, A. K., Ricardi, U., Suh, C., Mauch, P. M., Specht, Lena & Yahalom, J., 2018, In: International Journal of Radiation Oncology, Biology, Physics. 101, 4, p. 794-808 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  102. Published

    Radiation in Central Nervous System Leukemia: Guidelines From the International Lymphoma Radiation Oncology Group

    Pinnix, C. C., Yahalom, J., Specht, Lena & Dabaja, B. S., 2018, In: International Journal of Radiation Oncology, Biology, Physics. 102, 1, p. 53-58 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  103. Published

    Radiotherapy for Hodgkin Lymphoma Reducing Toxicity While Maintaining Efficacy

    Specht, Lena, 2018, In: Cancer journal (Sudbury, Mass.). 24, 5, p. 237-243 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Recommendations for the clinical management of the elderly patient with malignant lymphoma

    Specht, Lena, Aleman, B., Eich, H., Illidge, T. M., Kirova, Y., Mikhaeel, N. G., Ricardi, U., Yahalom, J. & International Lymphoma Radiation Oncology Group (ILROG), I. L. R. O. G. (., 2018, In: Annals of Oncology. 29, 4, p. 1069-1070 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Role of Radiation Therapy in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Guidelines from the International Lymphoma Radiation Oncology Group

    Ng, A. K., Yahalom, J., Goda, J. S., Constine, L. S., Pinnix, C. C., Kelsey, C. R., Hoppe, B., Oguchi, M., Suh, C., Wirth, A., Qi, S., Davies, A., Moskowitz, C. H., Laskar, S., Li, Y., Mauch, P. M., Specht, Lena & Illidge, T., 2018, In: International Journal of Radiation Oncology, Biology, Physics. 100, 3, p. 652-669

    Research output: Contribution to journalReviewResearchpeer-review

  106. Published

    TEDDI: radiotherapy delivery in deep inspiration for pediatric patients - a NOPHO feasibility study

    Lundgaard, A. Y., Hjalgrim, L. L., Rechner, L. A., Josipovic, Mirjana, Joergensen, M., Aznar, M. C., Berthelsen, A. K., Borgwardt, L., Johansen, Christoffer, Loft, A., Safwat, A. A., Vaalavirta, L., Specht, Lena & Maraldo, M. V., 2018, In: Radiation Oncology. 13, p. 1-6 56.

    Research output: Contribution to journalJournal articleResearchpeer-review

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