Lars Juhl Jensen
professor, group leader
Jensen Group
Blegdamsvej 3, 2200 København N., 06 Bygning 6, Building: 06-2-26
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Reply to 'Mining electronic health records: An additional perspective'
Jensen, P. B., Jensen, Lars Juhl & Brunak, Søren, 1 Jan 2013, In: Nature Reviews. Genetics. 14, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
STITCH: interaction networks of chemicals and proteins
Kuhn, M., von Mering, C., Campillos, M., Jensen, Lars Juhl & Bork, P., 2008, In: Nucleic Acids Research. 36, Database issue, p. D684-8Research output: Contribution to journal › Journal article › peer-review
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STITCH 2: an interaction network database for small molecules and proteins
Kuhn, M., Szklarczyk, D., Franceschini, A., Campillos, M., von Mering, C., Jensen, Lars Juhl, Beyer, A. & Bork, P., 2010, In: Nucleic Acids Research. 38, Database issue, p. D552-6Research output: Contribution to journal › Journal article › peer-review
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STITCH 3: zooming in on protein-chemical interactions
Kuhn, M., Szklarczyk, D., Franceschini, A., von Mering, C., Jensen, Lars Juhl & Bork, P., 2012, In: Nucleic Acids Research. 40, Database issue, p. D876-80Research output: Contribution to journal › Journal article › peer-review
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STITCH 4: integration of protein-chemical interactions with user data
Kuhn, M., Szklarczyk, D. M., Pletscher-Frankild, S., Blicher, T. H., von Mering, C., Jensen, Lars Juhl & Bork, P., 28 Nov 2013, In: Nucleic Acids Research. 42, D1, p. D401-D407 7 p.Research output: Contribution to journal › Journal article › peer-review
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STITCH 5: augmenting protein-chemical interaction networks with tissue and affinity data
Szklarczyk, D., Santos Delgado, A., von Mering, C., Jensen, Lars Juhl, Bork, P. & Kuhn, M., 2016, In: Nucleic Acids Research. 44, D1, p. D380-84 5 p.Research output: Contribution to journal › Journal article › peer-review
STRING: known and predicted protein-protein associations, integrated and transferred across organisms
von Mering, C., Jensen, Lars Juhl, Snel, B., Hooper, S. D., Krupp, M., Foglierini, M., Jouffre, N., Huynen, M. A. & Bork, P., 2005, In: Nucleic Acids Research. 33, Database issue, p. D433-7Research output: Contribution to journal › Journal article › peer-review
STRING 7--recent developments in the integration and prediction of protein interactions
von Mering, C., Jensen, Lars Juhl, Kuhn, M., Chaffron, S., Doerks, T., Krüger, B., Snel, B. & Bork, P., 2007, In: Nucleic Acids Research. 35, Database issue, p. D358-62Research output: Contribution to journal › Journal article › peer-review
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STRING 8--a global view on proteins and their functional interactions in 630 organisms
Jensen, Lars Juhl, Kuhn, M., Stark, M., Chaffron, S., Creevey, C., Muller, J., Doerks, T., Julien, P., Roth, A., Simonovic, M., Bork, P. & von Mering, C., 2008, In: Nucleic Acids Research. 37, suppl 1, p. D412-D416 5 p.Research output: Contribution to journal › Journal article › peer-review
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STRING v10: protein-protein interaction networks, integrated over the tree of life
Szklarczyk, D., Franceschini, A., Wyder, S., Forslund, K., Heller, D., Huerta-Cepas, J., Simonovic, M., Roth, A., Santos Delgado, A., Tsafou, K. P., Kuhn, M., Bork, P., Jensen, Lars Juhl & von Mering, C., 28 Jan 2015, In: Nucleic Acids Research. 43, D1, p. D447-52 6 p.Research output: Contribution to journal › Journal article › peer-review
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STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
Szklarczyk, D., Gable, A. L., Lyon, D., Junge, A., Wyder, S., Huerta-Cepas, J., Simonovic, M., Doncheva, Nadezhda Tsankova, Morris, J. H., Bork, P., Jensen, Lars Juhl & von Mering, C., 2019, In: Nucleic Acids Research. 47, D1, p. D607-D613 7 p.Research output: Contribution to journal › Journal article › peer-review
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STRING v9.1: Protein-protein interaction networks, with increased coverage and integration
Franceschini, A., Simonovic, M., Roth, A., Von Mering, C., Szklarczyk, D., Pletscher-Frankild, S., Jensen, Lars Juhl, Kuhn, M. M., Lin, J., Minguez, P. & Bork, P., 1 Jan 2013, In: Nucleic Acids Research. 41, D1, p. D808-D815 8 p.Research output: Contribution to journal › Journal article › peer-review
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SVD-phy: improved prediction of protein functional associations through singular value decomposition of phylogenetic profiles
Franceschini, A., Lin, J., von Mering, C. & Jensen, Lars Juhl, 2016, In: Bioinformatics. 32, 7, p. 1085-7 3 p.Research output: Contribution to journal › Journal article › peer-review
Scoring functions for computational algorithms applicable to the design of spiked oligonucleotides
Jensen, Lars Juhl, Andersen, K. V., Svendsen, A. & Kretzschmar, T., 1998, In: Nucleic Acids Research. 26, 3, p. 697-702 6 p.Research output: Contribution to journal › Journal article › peer-review
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Search Databases and Statistics: Pitfalls and Best Practices in Phosphoproteomics
Refsgaard, J. C., Munk, S. & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer Publishing Company, Vol. 1355. p. 323-39 17 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics Workflow
Deshmukh, Atul Shahaji, Cox, J., Jensen, Lars Juhl, Meissner, F. & Mann, Matthias, 6 Nov 2015, In: Journal of Proteome Research. 14, 11, p. 4885-95 11 p.Research output: Contribution to journal › Journal article › peer-review
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Seqenv: linking sequences to environments through text mining
Sinclair, L., Ijaz, U. Z., Jensen, Lars Juhl, Coolen, M. J. L., Gubry-Rangin, C., Chroňáková, A., Oulas, A., Pavloudi, C., Schnetzer, J., Weimann, A., Ijaz, A., Eiler, A., Quince, C. & Pafilis, E., 20 Dec 2016, In: PeerJ. 4, p. 1-17 17 p., e2690.Research output: Contribution to journal › Journal article › peer-review
Sequence-based feature prediction and annotation of proteins
Juncker, A., Jensen, Lars Juhl, Pierleoni, A., Bernsel, A., Tress, M. L., Bork, P., von Heijne, G., Valencia, A., Ouzounis, C. A., Casadio, R. & Brunak, S., 2009, In: Genome Biology (Online Edition). 10, 2, p. 206Research output: Contribution to journal › Journal article › peer-review
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Site-specific characterization of endogenous SUMOylation across species and organs
Hendriks, Ivo Alexander, Lyon, D., Su, D., Skotte, Niels Henning, Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Nature Communications. 9, p. 1-17 2456.Research output: Contribution to journal › Journal article › peer-review
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Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation
Hendriks, Ivo Alexander, Lyon, D., Young, C., Jensen, Lars Juhl, Vertegaal, A. C. O. & Nielsen, Michael Lund, Mar 2017, In: Nature Structural and Molecular Biology. 24, 3, p. 325-336 12 p.Research output: Contribution to journal › Journal article › peer-review
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SnapShot: S-Phase Entry and Exit
Burgess, A., Vuong, J., Marzec, K. A., de Lichtenberg, U. N., O'Donoghue, S. I. & Jensen, Lars Juhl, 2019, In: Cell. 179, 3, p. 802-802.e1 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing
Fedorov, O., Huber, K., Eisenreich, A., Filippakopoulos, P., King, O., Bullock, A. N., Szklarczyk, D., Jensen, Lars Juhl, Fabbro, D., Trappe, J., Rauch, U., Bracher, F. & Knapp, S., 2011, In: Chemistry & Biology. 18, 1, p. 67-76 10 p.Research output: Contribution to journal › Journal article › peer-review
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Specifying RNA-Binding Regions in Proteins by Peptide Cross-Linking and Affinity Purification
Mullari, M., Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2017, In: Journal of Proteome Research. 16, 8, p. 2762-2772 11 p.Research output: Contribution to journal › Journal article › peer-review
Spore number control and breeding in saccharomyces cerevisiae a key role for a self-organixzing system
Taxis, C., Kavagiou, Z., Keller, P., Jensen, Lars Juhl, Colombelli, J., Bork, P., Stelzer, E. H. K. & Knop, M., 2005, In: Journal of Cell Biology. 171, p. 627-640Research output: Contribution to journal › Journal article › peer-review
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Standardized benchmarking in the quest for orthologs
Altenhoff, A. M., Boeckmann, B., Capella-Gutierrez, S., Dalquen, D. A., DeLuca, T., Forslund, K., Huerta-Cepas, J., Linard, B., Pereira, C., Pryszcz, L. P., Schreiber, F., da Silva, A. S., Szklarczyk, D., Train, C., Bork, P., Lecompte, O., von Mering, C., Xenarios, I., Sjölander, K., Jensen, Lars Juhl, Martin, M. J., Muffato, M., Gabaldón, T., Lewis, S. E., Thomas, P. D., Sonnhammer, E., Dessimoz, C. & Quest for Orthologs consortium, Q. F. O. C., May 2016, In: Nature Methods. 13, p. 425-30 6 p.Research output: Contribution to journal › Journal article › peer-review
Structural analysis of DNA sequence: evidence for lateral gene transfer in Thermotoga maritima
Worning, P., Jensen, Lars Juhl, Nelson, K. E., Brunak, S. & Ussery, D., 2000, In: Nucleic Acids Research. 28, 3, p. 706-9 4 p.Research output: Contribution to journal › Journal article › peer-review
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Structure-based discovery of novel US28 small molecule ligands with different modes of action
Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296Research output: Contribution to journal › Journal article › peer-review
SuperTarget and Matador: resources for exploring drug-target relationships
Günther, S., Kuhn, M., Dunkel, M., Campillos, M., Senger, C., Petsalaki, E., Ahmed, J., Urdiales, E. G., Gewiess, A., Jensen, Lars Juhl, Schneider, R., Skoblo, R., Russell, R. B., Bourne, P. E., Bork, P. & Preissner, R., 2008, In: Nucleic Acids Research. 36, Database issue, p. D919-22Research output: Contribution to journal › Journal article › peer-review
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Suppression of water as a nucleophile in Candida antarctica lipase B catalysis
Larsen, M. W., Zielinska, D. F., Martinelle, M., Hidalgo, A., Jensen, Lars Juhl, Bornscheuer, U. T. & Hult, K., 12 Apr 2010, In: ChemBioChem. 11, 6, p. 796-801 6 p.Research output: Contribution to journal › Journal article › peer-review
Systematic association of genes to phenotypes by genome and literature mining
Korbel, J. O., Doerks, T., Jensen, Lars Juhl, Perez-Iratxeta, C., Kaczanowski, S., Hooper, S. D., Andrade, M. A. & Bork, P., 2005, In: P L o S Biology (Online). 3, 5, p. e134Research output: Contribution to journal › Journal article › peer-review
Systematic discovery of in vivo phosphorylation networks
Linding, R., Jensen, Lars Juhl, Ostheimer, G. J., van Vugt, M. A. T. M., Jørgensen, C., Miron, I. M., Diella, F., Colwill, K., Taylor, L., Elder, K., Metalnikov, P., Nguyen, V., Pasculescu, A., Jin, J., Park, J. G., Samson, L. D., Woodgett, J. R., Russell, R. B., Bork, P., Yaffe, M. B. & Pawson, T., 2007, In: Cell. 129, 7, p. 1415-26 12 p.Research output: Contribution to journal › Journal article › peer-review
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Systematic identification of proteins that elicit drug side effects
Kuhn, M., Al Banchaabouchi, M., Campillos, M., Jensen, Lars Juhl, Gross, C., Gavin, A. & Bork, P., 30 Apr 2013, In: Molecular Systems Biology. 9, p. 663 9 p.Research output: Contribution to journal › Journal article › peer-review
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Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation
Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Cell Reports. 24, 9, p. 2493-2505Research output: Contribution to journal › Journal article › peer-review
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TCRD and Pharos 2021: mining the human proteome for disease biology
Sheils, T. K., Mathias, S. L., Kelleher, K. J., Siramshetty, V. B., Nguyen, D. T., Bologa, C. G., Jensen, Lars Juhl, Vidović, D., Koleti, A., Schürer, S. C., Waller, A., Yang, J. J., Holmes, J., Bocci, G., Southall, N., Dharkar, P., Mathé, E., Simeonov, A. & Oprea, T. I., 2021, In: Nucleic Acids Research. 49, D1, p. D1334-D1346 13 p.Research output: Contribution to journal › Journal article › peer-review
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TIGA: target illumination GWAS analytics
Yang, J. J., Grissa, Dhouha, Lambert, C. G., Bologa, C. G., Mathias, S. L., Waller, A., Wild, D. J., Jensen, Lars Juhl & Oprea, T. I., 2021, In: Bioinformatics. 37, 21, p. 3865-3873Research output: Contribution to journal › Journal article › peer-review
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TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells
Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, José, Jensen, Lars Juhl, Gupta, R., Lademann, U. A., Brünner, N., Olsen, Jesper Velgaard & Stenvang, Jan, 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.Research output: Contribution to journal › Journal article › peer-review
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TIN-X: target importance and novelty explorer
Cannon, D. C., Yang, J. J., Mathias, S. L., Ursu, O., Mani, S., Waller, A., Schürer, S. C., Jensen, Lars Juhl, Sklar, L. A., Bologa, C. G. & Oprea, T. I., 15 Aug 2017, In: Bioinformatics. 33, 16, p. 2601-2603 3 p.Research output: Contribution to journal › Journal article › peer-review
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TISSUES 2.0: an integrative web resource on mammalian tissue expression
Palasca, Oana, Santos, A., Stolte, C., Gorodkin, Jan & Jensen, Lars Juhl, 2018, In: Database: The Journal of Biological Databases and Curation. 2018, 1, p. 1-12Research output: Contribution to journal › Journal article › peer-review
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Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients
Jensen, A. B., Moseley, P. L., Oprea, T. I., Ellesøe, S. G., Eriksson, R., Schmock, H., Jensen, P. B., Jensen, Lars Juhl & Brunak, Søren, 24 Jun 2014, In: Nature Communications. 5, 10 p., 4022.Research output: Contribution to journal › Journal article › peer-review
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Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation
Emdal, Kristina Bennet, Pedersen, Anna-Kathrine, Bekker-Jensen, D. B., Tsafou, K. P., Horn, H., Lindner, S., Schulte, J. H., Eggert, A., Jensen, Lars Juhl, Francavilla, C. & Olsen, Jesper Velgaard, 2015, In: Science Signaling. 8, 374, ra40.Research output: Contribution to journal › Journal article › peer-review
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Ten simple rules for getting help from online scientific communities
Dall'olio, G. M., Marino, J., Schubert, M., Keys, K. L., Stefan, M. I., Gillespie, C. S., Poulain, P., Shameer, K., Sugar, R., Invergo, B. M., Jensen, Lars Juhl, Bertranpetit, J. & Laayouni, H., 1 Sep 2011, In: P L o S Computational Biology. 7, 9, p. e1002202Research output: Contribution to journal › Journal article › peer-review
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Text mining for biology--the way forward: opinions from leading scientists
Altman, R. B., Bergman, C. M., Blake, J., Blaschke, C., Cohen, A., Gannon, F., Grivell, L., Hahn, U., Hersh, W., Hirschman, L., Jensen, Lars Juhl, Krallinger, M., Mons, B., O'Donoghue, S. I., Peitsch, M. C., Rebholz-Schuhmann, D., Shatkay, H. & Valencia, A., 2008, In: Genome Biology (Online Edition). 9 Suppl 2, p. S7Research output: Contribution to journal › Journal article › peer-review
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The SIDER database of drugs and side effects
Kuhn, M., Letunic, I., Jensen, Lars Juhl & Bork, P., 4 Jan 2016, In: Nucleic Acids Research. 44, p. D1075-9Research output: Contribution to journal › Journal article › peer-review
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The SPECIES and ORGANISMS Resources for Fast and Accurate Identification of Taxonomic Names in Text
Pafilis, E., Pletscher-Frankild, S., Fanini, L., Faulwetter, S., Pavloudi, C., Vasileiadou, A., Arvanitidis, C. & Jensen, Lars Juhl, 18 Jun 2013, In: PloS one. 8, 6, p. e65390Research output: Contribution to journal › Journal article › peer-review
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The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
Szklarczyk, D., Franceschini, A., Kuhn, M., Simonovic, M., Roth, A., Minguez, P., Doerks, T., Stark, M., Muller, J., Bork, P., Jensen, Lars Juhl & von Mering, C., 2011, In: Nucleic Acids Research. 39, Database issue, p. D561-8Research output: Contribution to journal › Journal article › peer-review
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The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible
Szklarczyk, D., Morris, J. H., Cook, H., Kuhn, M., Wyder, S., Simonovic, M., Santos Delgado, A., Doncheva, Nadezhda Tsankova, Roth, A., Bork, P., Jensen, Lars Juhl & von Mering, C., Jan 2017, In: Nucleic Acids Research. 45, D1, p. D362-D368Research output: Contribution to journal › Journal article › peer-review
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The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets
Szklarczyk, D., Gable, A. L., Nastou, Katerina, Lyon, D., Kirsch, Rebecca, Pyysalo, S., Doncheva, Nadezhda Tsankova, Legeay, M., Fang, T., Bork, P., Jensen, Lars Juhl & von Mering, C., 2021, In: Nucleic Acids Symposium Series. 49, D1, p. D605-D612 8 p.Research output: Contribution to journal › Journal article › peer-review
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The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest
Szklarczyk, D., Kirsch, Rebecca, Koutrouli, Mikaela, Nastou, Katerina, Mehryary, F., Hachilif, R., Gable, A. L., Fang, T., Doncheva, Nadezhda Tsankova, Pyysalo, S., Bork, P., Jensen, Lars Juhl & von Mering, C., 2023, In: Nucleic Acids Research. 51, D1, p. D638-D646 9 p.Research output: Contribution to journal › Journal article › peer-review
The atlas visualisation of genome-wide information
Skovgaard, M., Jensen, Lars Juhl, Friis, C., Stærfeldt, H. H., Worning, P., Brunak, S. & Ussery, D. W., 2002, Methods in Microbiology. Vol. 33. p. 49-63Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production
Geissler, Adrian Sven, Poulsen, L. D., Doncheva, Nadezhda Tsankova, Anthon, Christian, Seemann, Ernst Stefan, González-Tortuero, E., Breüner, A., Jensen, Lars Juhl, Hjort, C., Vinther, Jeppe & Gorodkin, Jan, 2022, In: Frontiers in Microbiology. 13, 17 p., 909493.Research output: Contribution to journal › Journal article › peer-review
ID: 9931112
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TISSUES 2.0: an integrative web resource on mammalian tissue expression
Research output: Contribution to journal › Journal article › peer-review
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438
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STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
Research output: Contribution to journal › Journal article › peer-review
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424
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Drug target ontology to classify and integrate drug discovery data
Research output: Contribution to journal › Journal article › peer-review
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