Kristoffer Enøe Johansson

Kristoffer Enøe Johansson

Academic employee FU


  1. 2024
  2. Published

    A mutational atlas for Parkin proteostasis

    Clausen, L., Voutsinos, Vasileios, Cagiada, Matteo, Johansson, Kristoffer Enøe, Grønbæk-Thygesen, Martin, Nariya, S., Powell, R. L., Have, M. K. N., Østergaard, Vibe Hallundbæk, Stein, Amelie, Fowler, D. M., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2024, In: Nature Communications. 15, 1, 17 p., 1541.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Conformational ensembles of the human intrinsically disordered proteome

    Tesei, Giulio, Trolle, A. I., Jonsson, Nicolas, Betz, J., Knudsen, F. E., Pesce, Francesco, Johansson, Kristoffer Enøe & Lindorff-Larsen, Kresten, 2024, In: Nature. 626, p. 897-904 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. 2023
  5. Published

    Global analysis of multi-mutants to improve protein function

    Johansson, Kristoffer Enøe, Lindorff-Larsen, Kresten & Winther, Jakob R., 2023, In: Journal of Molecular Biology. 435, 8, 15 p., 168034.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    HSP70-binding motifs function as protein quality control degrons

    Abildgaard, A. B., Voutsinos, Vasileios, Petersen, S. D., Larsen, Fia Brunsgaard Valsted, Kampmeyer, Caroline, Johansson, Kristoffer Enøe, Stein, Amelie, Ravid, T., Andréasson, C., Jensen, M. K., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: Cellular and Molecular Life Sciences. 80, 1, 17 p., 32.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Prediction of Quality-control Degradation Signals in Yeast Proteins

    Johansson, Kristoffer Enøe, Mashahreh, B., Hartmann-Petersen, Rasmus, Ravid, T. & Lindorff-Larsen, Kresten, 2023, In: Journal of Molecular Biology. 435, 2, 9 p., 167915.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Rapid protein stability prediction using deep learning representations

    Blaabjerg, Lasse Møller, Kassem, M. M., Good, L. L., Jonsson, Nicolas, Cagiada, Matteo, Johansson, Kristoffer Enøe, Boomsma, Wouter, Stein, Amelie & Lindorff-Larsen, Kresten, 2023, In: eLife. 12, 19 p., e82593.

    Research output: Contribution to journalJournal articlepeer-review

  9. 2022
  10. Published

    14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes

    Gjesing, A. P., Engelbrechtsen, L., Cathrine B. Thuesen, A., Have, C. T., Hollensted, M., Grarup, N., Linneberg, A., Steen Nielsen, J., Christensen, L. B., Thomsen, R. W., Johansson, K. E., Cagiada, M., Gersing, S., Hartmann-Petersen, R., Lindorff-Larsen, K., Vaag, A., Sørensen, H. T., Brandslund, I., Beck-Nielsen, H., Pedersen, O. & 2 others, Rungby, Jørgen & Hansen, Torben, 2022, In: Diabetes Research and Clinical Practice. 194, 9 p., 110159.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Conserved degronome features governing quality control associated proteolysis

    Mashahreh, B., Armony, S., Johansson, Kristoffer Enøe, Chappleboim, A., Friedman, N., Gardner, R. G., Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten & Ravid, T., 2022, In: Nature Communications. 13, 1, 13 p., 7588.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Increasing protein stability by inferring substitution effects from high-throughput experiments

    Norrild, R. K., Johansson, Kristoffer Enøe, O'Shea, Charlotte, Morth, J. P., Lindorff-Larsen, Kresten & Winther, Jakob R., 2022, In: Cell Reports Methods. 2, 11, 11 p., 100333.

    Research output: Contribution to journalJournal articlepeer-review

  13. 2021
  14. Published

    Charge Interactions in a Highly Charge-Depleted Protein

    Hervø-Hansen, S., Højgaard, C., Johansson, Kristoffer Enøe, Wang, Yong, Wahni, K., Young, D., Messens, J., Teilum, Kaare, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: Journal of the American Chemical Society. 143, 6, p. 2500-2508 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold

    Marin, Frederikke Isa, Johansson, Kristoffer Enøe, O'Shea, Charlotte, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: The Journal of Physical Chemistry B. 125, 40, p. 11141-11149

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Substitutional landscape of a split fluorescent protein fragment using high-density peptide microarrays

    Antonescu, O. N., Rasmussen, A., Damm, N. A. M., Heidemann, Ditte Fogh, Popov, R., Nesterov-Mueller, A., Johansson, Kristoffer Enøe & Winther, Jakob R., 2021, In: PLoS ONE. 16, 2, 17 p., e0241461.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance

    Cagiada, Matteo, Johansson, Kristoffer Enøe, Valanciute, A., Nielsen, S. V., Hartmann-Petersen, Rasmus, Yang, J. J., Fowler, D. M., Stein, Amelie & Lindorff-Larsen, Kresten, 2021, In: Molecular Biology and Evolution. 38, 8, p. 3235-3246

    Research output: Contribution to journalJournal articlepeer-review

  18. 2020
  19. Published

    Global analysis of protein stability by temperature and chemical denaturation

    Hamborg, L., Horsted, E. W., Johansson, Kristoffer Enøe, Willemoës, Martin, Lindorff-Larsen, Kresten & Teilum, Kaare, 2020, In: Analytical Biochemistry. 605, 7 p., 113863.

    Research output: Contribution to journalJournal articlepeer-review

  20. 2019
  21. Published

    Improving folding properties of computationally designed proteins

    Bjerre, B., Nissen, J., Madsen, M., Kamarauskaite, J., Norrild, R. K., Holm, Peter Christoffer, Nordentoft, M. K., O'Shea, Charlotte, Willemoës, Martin, Johansson, Kristoffer Enøe & Winther, Jakob R., 13 Dec 2019, In: Protein Engineering Design and Selection (Print). 32, 3, p. 145-151 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Shining light on split fluorescent protein fitness landscapes using peptide array-based deep substitutional scanning

    ANTONESCU, O., Johansson, Kristoffer Enøe & Winther, Jakob R., 30 Jun 2019.

    Research output: Contribution to conferencePosterResearchpeer-review

  23. 2018
  24. Published

    Comprehensive mapping of GFP structure-function relationship using high-density peptide arrays

    Antonescu, O., Johansson, Kristoffer Enøe & Winther, Jakob R., 10 Jul 2018.

    Research output: Contribution to conferencePosterResearchpeer-review

  25. Published

    Characterization of the hydrodynamics in a miniaturized dissolution apparatus

    Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Protein evolution: Hacking an enzyme

    Johansson, Kristoffer Enøe & Winther, Jakob R., 2018, In: Nature Chemical Biology. 14, 3, p. 202-204 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  27. Published

    Structural heterogeneity and dynamics in protein evolution and design

    Johansson, Kristoffer Enøe & Lindorff-Larsen, Kresten, 2018, In: Current Opinion in Structural Biology. 48, p. 157-163 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. 2017
  29. Published

    Tracking dehydration mechanisms in crystalline hydrates with molecular dynamics simulations

    Larsen, A. S., Ruggiero, M. T., Johansson, Kristoffer Enøe, Zeitler, J. A. & Rantanen, Jukka, Oct 2017, In: Crystal Growth & Design. 17, 10, p. 5017-5022 6 p.

    Research output: Contribution to journalLetterpeer-review

  30. Published

    Computational Dehydration of Crystalline Hydrates Using Molecular Dynamics Simulations

    Larsen, A. S., Rantanen, Jukka & Johansson, Kristoffer Enøe, 2017, In: Journal of Pharmaceutical Sciences. 106, 1, p. 348-355 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. 2016
  32. Published

    Local structure in the disordered solid solution of cis- and trans-perinones

    Teteruk, J. L., Glinnemann, J., Heyse, W., Johansson, Kristoffer Enøe, van de Streek, J. & Schmidt, M. U., Jun 2016, In: Acta Crystallographica. Section B: Structural Science. B72, p. 416-433 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Revision of the Crystal Structure of the First Molecular Polymorph in History

    Johansson, Kristoffer Enøe & Van De Streek, J., 2 Mar 2016, In: Crystal Growth & Design. 16, 3, p. 1366-1370 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    A soluble, folded protein without charged amino acid residues

    Højgaard, C., Kofoed, C., Espersen, R., Johansson, Kristoffer Enøe, Villa, M., Willemoës, Martin, Lindorff-Larsen, Kresten, Teilum, Kaare & Winther, Jakob R., 2016, In: Biochemistry. 55, 28, p. 3949–3956 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template

    Johansson, Kristoffer Enøe, Johansen, Nicolai Tidemand, Christensen, S., Horowitz, S., Bardwell, J. C. A., Olsen, Johan Gotthardt, Willemoës, Martin, Lindorff-Larsen, Kresten, Ferkinghoff-Borg, J., Hamelryck, Thomas Wim & Winther, Jakob R., 2016, In: Journal of Molecular Biology. 428, 21, p. 4361-4377 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. 2014
  37. Published

    Distinguishing tautomerism in the crystal structure of (Z)-N-(5-ethyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene)-4-methylbenzenesulfonamide using DFT-D calculations and (13)C solid-state NMR

    Li, X., Bond, A. D., Johansson, Kristoffer Enøe & Van de Streek, J., 15 Aug 2014, In: Acta Crystallographica. Section C: Crystal Structure Communications. C70, Pt 8, p. 784-9 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. 2013
  39. Published

    A simple probabilistic model of multibody interactions in proteins

    Johansson, Kristoffer Enøe & Hamelryck, Thomas Wim, 2013, In: Proteins: Structure, Function, and Bioinformatics. 81, 8, p. 1340-1350 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    PHAISTOS: a framework for Markov chain Monte Carlo simulation and inference of protein structure

    Boomsma, Wouter, Frellsen, J., Harder, T. P., Bottaro, S., Johansson, Kristoffer Enøe, Tian, P., Stovgaard, K., Andreetta, C., Olsson, S., Valentin, J., Antonov, L. D., Christensen, A. S., Borg, M., Jensen, Jan Halborg, Lindorff-Larsen, Kresten, Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2013, In: Journal of Computational Chemistry. 34, 19, p. 1697-1705 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Phaistos user manual

    Boomsma, Wouter, Bottaro, S., Hamelryck, Thomas Wim, Frellsen, J., Andreetta, C., Borg, M., Harder, T., Johansson, Kristoffer Enøe, Stovgaard, K. & Tian, P., 2013, 90 p.

    Research output: Book/ReportBook

  42. 2012
  43. Published

    Computational Protein Design

    Johansson, Kristoffer Enøe, 2012, Department of Biology, Faculty of Science, University of Copenhagen. 151 p.

    Research output: Book/ReportPh.D. thesis

  44. Published

    Subtle Monte Carlo updates in dense molecular systems

    Bottaro, S., Boomsma, Wouter, Johansson, Kristoffer Enøe, Andreetta, C., Hamelryck, Thomas Wim & Ferkinghoff-Borg, J., 2012, In: Journal of Chemical Theory and Computation. 8, 2, p. 695-702 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. 2011
  46. Published

    Efficient, non-disruptive local moves for Monte Carlo sampling of proteins

    Bottaro, S., Boomsma, Wouter, Johansson, Kristoffer Enøe, Andreetta, C., Hamelryck, Thomas Wim & Ferkinghoff-Borg, J., 2011, Next Generation Statistics in Biosciences: Proceedings of the 30th Leeds Annual Statistical Research (LASR) Workshop. Mardia, K. V., Gusnanto, A., Riley, A. D. & Voss, J. (eds.). University of Leeds, p. 127 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  47. 2010
  48. Published

    Beyond rotamers: a generative, probabilistic model of side chains in proteins

    Harder, T., Boomsma, Wouter, Paluszewski, M., Frellsen, J., Johansson, Kristoffer Enøe & Hamelryck, Thomas Wim, 1 Jan 2010, In: B M C Bioinformatics. 11, p. 306

    Research output: Contribution to journalJournal articlepeer-review

ID: 11048943