Kristina Bennet Emdal

Kristina Bennet Emdal

Assistant Professor, Special Consultant

Member of:


    1. 2023
    2. Published
    3. 2022
    4. Published

      Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance

      Emdal, Kristina Bennet, Palacio-Escat, N., Wigerup, C., Eguchi, A., Nilsson, H., Bekker-Jensen, D. B., Rönnstrand, L., Kazi, J. U., Puissant, A., Itzykson, R., Saez-Rodriguez, J., Masson, K., Blume-Jensen, P. & Olsen, Jesper Velgaard, 2022, In: Cell Reports. 40, 6, 25 p., 111177.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. 2021
    6. Published

      Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses

      Dugourd, A., Kuppe, C., Sciacovelli, M., Gjerga, E., Gabor, A., Emdal, Kristina Bennet, Vieira, V., Bekker-Jensen, D. B., Kranz, J., Bindels, E. M. J., Costa, A. S. H., Sousa, A., Beltrao, P., Rocha, M., Olsen, Jesper Velgaard, Frezza, C., Kramann, R. & Saez-Rodriguez, J., 2021, In: Molecular Systems Biology. 17, 1, 17 p., e9730.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. 2020
    8. Published

      Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues

      Emdal, Kristina Bennet & Lundby, Alicia, 2020, In: Molecular & Cellular Oncology. 7, 1, 3 p., e1692643.

      Research output: Contribution to journalComment/debateResearchpeer-review

    9. 2019
    10. Published

      Dynamic lineage priming is driven via direct enhancer regulation by ERK

      Hamilton, W. B., Mosesson, Y., S. Monteiro, Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In: Nature. 575, p. 355-360

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

      Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. 2018
    13. Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

      Randall, E. C., Emdal, K. B., Laramy, J. K., Kim, M., Roos, A., Calligaris, D., Regan, M. S., Gupta, S. K., Mladek, A. C., Carlson, B. L., Johnson, A. J., Lu, F-K., Xie, X. S., Joughin, B. A., Reddy, R. J., Peng, S., Abdelmoula, W. M., Jackson, P. R., Kolluri, A., Kellersberger, K. A. & 8 others, Agar, J. N., Lauffenburger, D. A., Swanson, K. R., Tran, N. L., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., 21 Nov 2018, In: Nature Communications. 9, 1, p. 4904

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma

      Emdal, Kristina Bennet, Pedersen, Anna-Kathrine, Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Identifying and targeting sporadic oncogenic genetic aberrations in mouse models of triple-negative breast cancer

      Liu, H., Murphy, C. J., Karreth, F. A., Emdal, Kristina Bennet, Yang, K., White, F. M., Elemento, O., Toker, A., Wulf, G. M. & Cantley, L. C., 2018, In: Cancer Discovery. 8, 3, p. 354-369 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. 2017
    17. Characterization of in vivo resistance to osimertinib and JNJ-61186372, an EGFR/Met bispecific antibody, reveals unique and consensus mechanisms of resistance

      Emdal, Kristina Bennet, Dittmann, A., Reddy, R. J., Lescarbeau, R. S., Moores, S. L., Laquerre, S. & White, F. M., 1 Nov 2017, In: Molecular Cancer Therapeutics. 16, 11, p. 2572-2585 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Combinatorial Drug Screening Identifies Ewing Sarcoma–specific Sensitivities

      Radic-Sarikas, B., Tsafou, K. P., Emdal, Kristina Bennet, Papamarkou, T., Huber, K. V. M., Mutz, C., Toretsky, J. A., Bennett, K. L., Olsen, Jesper Velgaard, Brunak, S., Kovar, H. & Superti-Furga, G., Jan 2017, In: Molecular Cancer Therapeutics. 16, 1, p. 88-101 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. 2015
    20. Published

      Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation

      Emdal, Kristina Bennet, Pedersen, Anna-Kathrine, Bekker-Jensen, D. B., Tsafou, K. P., Horn, H., Lindner, S., Schulte, J. H., Eggert, A., Jensen, Lars Juhl, Francavilla, C. & Olsen, Jesper Velgaard, 2015, In: Science Signaling. 8, 374, ra40.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2013
    22. Published

      Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs

      Francavilla, C., Rigbolt, K. T. G., Emdal, Kristina Bennet, Carraro, G., Vernet, E., Bekker-Jensen, D. B., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, Jesper Velgaard, 26 Sep 2013, In: Molecular Cell. 51, 6, p. 707-22 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. 2012
    24. Published

      NFkB signaling is important for growth of antiestrogen resistant breast cancer cells

      Yde, C. W., Emdal, Kristina Bennet, Guerra, B. & Lykkesfeldt, A. E., 2012, In: Breast Cancer Research and Treatment. 135, 1, p. 67-78 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. 2010
    26. Published

      Breast cancer cells can switch between estrogen receptor alpha and ErbB signaling and combined treatment against both signaling pathways postpones development of resistance

      Sonne-Hansen, Katrine, Norrie, I. C., Emdal, Kristina Bennet, Benjaminsen, R. V., Frogne, T., Christiansen, I. J., Kirkegaard, T. & Lykkesfeldt, A. E., 2010, In: Breast Cancer Research and Treatment. 121, 3, p. 601-13 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 33521777