Kristina Bennet Emdal
Assistant Professor
- 2023
- E-pub ahead of print
Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, Anders Handrup, Østergaard, Ole, Emdal, Kristina Bennet, Svane, Inge Marie & Olsen, Jesper Velgaard, 2023, (E-pub ahead of print) In: Proteomics.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
Emdal, Kristina Bennet, Palacio-Escat, N., Wigerup, C., Eguchi, Akihiro, Nilsson, H., Bekker-Jensen, D. B., Rönnstrand, L., Kazi, J. U., Puissant, A., Itzykson, R., Saez-Rodriguez, J., Masson, K., Blume-Jensen, P. & Olsen, Jesper Velgaard, 2022, In: Cell Reports. 40, 6, 25 p., 111177.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses
Dugourd, A., Kuppe, C., Sciacovelli, M., Gjerga, E., Gabor, A., Emdal, Kristina Bennet, Vieira, V., Bekker-Jensen, D. B., Kranz, J., Bindels, E. M. J., Costa, A. S. H., Sousa, A., Beltrao, P., Rocha, M., Olsen, Jesper Velgaard, Frezza, C., Kramann, R. & Saez-Rodriguez, J., 2021, In: Molecular Systems Biology. 17, 1, 17 p., e9730.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues
Emdal, Kristina Bennet & Lundby, Alicia, 2020, In: Molecular & Cellular Oncology. 7, 1, 3 p., e1692643.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2019
- Published
Dynamic lineage priming is driven via direct enhancer regulation by ERK
Hamilton, W. B., Mosesson, Y., S. Monteiro, Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In: Nature. 575, p. 355-360Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma
Randall, E. C., Emdal, Kristina Bennet, Laramy, J. K., Kim, M., Roos, A., Calligaris, D., Regan, M. S., Gupta, S. K., Mladek, A. C., Carlson, B. L., Johnson, A. J., Lu, F., Xie, X. S., Joughin, B. A., Reddy, R. J., Peng, S., Abdelmoula, W. M., Jackson, P. R., Kolluri, A., Kellersberger, K. A., Agar, J. N., Lauffenburger, D. A., Swanson, K. R., Tran, N. L., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., 21 Nov 2018, In: Nature Communications. 9, 1, p. 4904Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
Emdal, Kristina Bennet, Pedersen, Anna-Kathrine, Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.Research output: Contribution to journal › Journal article › Research › peer-review
Identifying and targeting sporadic oncogenic genetic aberrations in mouse models of triple-negative breast cancer
Liu, H., Murphy, C. J., Karreth, F. A., Emdal, Kristina Bennet, Yang, K., White, F. M., Elemento, O., Toker, A., Wulf, G. M. & Cantley, L. C., 2018, In: Cancer Discovery. 8, 3, p. 354-369 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
Characterization of in vivo resistance to osimertinib and JNJ-61186372, an EGFR/Met bispecific antibody, reveals unique and consensus mechanisms of resistance
Emdal, Kristina Bennet, Dittmann, A., Reddy, R. J., Lescarbeau, R. S., Moores, S. L., Laquerre, S. & White, F. M., 1 Nov 2017, In: Molecular Cancer Therapeutics. 16, 11, p. 2572-2585 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33521777
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
252
downloads
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
71
downloads
Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published