Kristian Strømgaard
Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
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A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain
Thorsen, T. S., Madsen, Kenneth Lindegaard, Dyhring, T., Bach, Anders, Peters, D., Strømgaard, Kristian, Rønn, L. C. B. & Gether, Ulrik, 1 Aug 2011, In: Combinatorial Chemistry & High Throughput Screening. 14, 7, p. 590-600 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A heteromeric snake toxin and the molecular details of pain perception
Strømgaard, Kristian & Kristensen, Anders Skov, 23 Apr 2012, In: Angewandte Chemie International Edition. 51, 17, p. 4009-4011Research output: Contribution to journal › Journal article › Research › peer-review
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A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage
Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322Research output: Contribution to journal › Journal article › Research › peer-review
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A sequential binding mechanism in a PDZ domain
Chi, C. N., Bach, Anders, Engström, Å., Wang, H., Strømgaard, Kristian, Gianni, S. & Jemth, P., 2009, In: Biochemistry. 48, 30, p. 7089-7097Research output: Contribution to journal › Journal article › Research › peer-review
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AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins
Strømgaard, Kristian & Mellor, I., Sep 2004, In: Medicinal Research Reviews. 24, 5, p. 589-620 32 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An expanded view of the protein folding landscape of PDZ domains
Hultqvist, G., Pedersen, S. W., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., 11 May 2012, In: Biochemical and Biophysical Research Communications. 421, 3, p. 550-553 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antidepressive lægemidler: nu i 3D
Andersen, J., Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, Dec 2010, In: Lægemiddelforskning. 2010, p. 25-27Research output: Contribution to journal › Journal article › Communication
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Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists
Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451Research output: Contribution to journal › Journal article › Research › peer-review
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Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97
Chi, C. N., Bach, Anders, Engström, Å., Strømgaard, Kristian, Lundström, P., Ferguson, N. & Jemth, P., 4 Feb 2011, In: Journal of Biological Chemistry. 286, 5, p. 3597-3606Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction
Bach, Anders, Eildal, J. N. N., Stuhr-Hansen, N., Deeskamp, R., Gottschalk, M., Pedersen, S. W., Kristensen, Anders Skov & Strømgaard, Kristian, 10 Mar 2011, In: Journal of Medicinal Chemistry. 54, 5, p. 1333-1346Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical biology
Strømgaard, Kristian, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 59-74Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Chemistry and biology of terpene trilactones from Ginkgo biloba
Strømgaard, Kristian & Nakanishi, K., 19 Mar 2004, In: Angewandte Chemie International Edition. 43, 13, p. 1640-1658 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors
Brier, T. J., Mellor, I. R., Tikhonov, D. B., Neagoe, I., Shao, Z., Brierley, M. J., Strømgaard, Kristian, Jaroszewski, J. W., Krogsgaard-Larsen, Povl & Usherwood, P. N. R., Oct 2003, In: Molecular Pharmacology. 64, 4, p. 954-964 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example
Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In: Journal of Biological Chemistry. 285, 36, p. 28252-28260Research output: Contribution to journal › Journal article › Research › peer-review
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Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction
Bach, Anders, Chi, C. N., Pang, G. F., Olsen, L., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 51, p. 9685-9689Research output: Contribution to journal › Journal article › Research › peer-review
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Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist
Andersen, T. F., Vogensen, S. B., Jensen, L. S., Knapp, K. M. & Strømgaard, Kristian, 1 Sep 2005, In: Bioorganic & Medicinal Chemistry. 13, 17, p. 5104-5112 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Design, synthesis, and pharmacological characterization of polyamine toxin derivatives: potent ligands for the pore-forming region of AMPA receptors
Jensen, L. S., Bølcho, U., Egebjerg, J. & Strømgaard, Kristian, Apr 2006, In: ChemMedChem. 1, 4, p. 419-428 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction
Gottschalk, M., Bach, Anders, Hansen, J. L., Krogsgaard-Larsen, Povl, Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Neurochemical Research. 34, 10, p. 1729-1737Research output: Contribution to journal › Journal article › Research › peer-review
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Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors
Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.Research output: Contribution to conference › Poster › Research
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Expedient synthesis of 1,3-substituted benzene peptidomimetics
Bach, Anders & Strømgaard, Kristian, 8 Feb 2011, In: Synthesis. 2011, 5, p. 807-815Research output: Contribution to journal › Journal article › Research › peer-review
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Expressed protein ligation of ionotropic glutamate receptors
Jensen, M. S., Kristensen, Anders Skov & Strømgaard, Kristian, 2007, In: Biopolymers. 88, 4, p. 602Research output: Contribution to journal › Conference abstract in journal › Research
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From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: Synthesis and structure-activity relationship studies
Eildal, J. N. N., Andersen, J., Kristensen, Anders Skov, Jørgensen, A. M., Bang-Andersen, B., Jørgensen, M. & Strømgaard, Kristian, 2008, In: Journal of Medicinal Chemistry. 51, 10, p. 3045-3048Research output: Contribution to journal › Journal article › Research › peer-review
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General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors
Lucas, S., Poulsen, Mette Homann, Nørager, N. G., Barslund, A. F., Bach, T. B., Kristensen, Anders Skov & Strømgaard, Kristian, 26 Nov 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10297-10301 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling
Strømgaard, Kristian, 2008, In: Carlsbergfondet. Aarsskrift. p. 42-47Research output: Contribution to journal › Journal article › Communication
Ginkgolide derivatives for photolabeling studies: preparation and pharmacological evaluation
Strømgaard, Kristian, Saito, D. R., Shindou, H., Ishii, S., Shimizu, T. & Nakanishi, K., 29 Aug 2002, In: Journal of Medicinal Chemistry. 45, 18, p. 4038-4046 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302559
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
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