Kristian Strømgaard
Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
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Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter
Andersen, J., Olsen, L., Hansen, K. B., Taboureau, O., Jørgensen, Flemming Steen, Jørgensen, A. M., Bang-Andersen, B., Egebjerg, J., Strømgaard, Kristian & Kristensen, Anders Skov, 2010, In: Journal of Biological Chemistry. 285, 3, p. 2051-2063Research output: Contribution to journal › Journal article › Research › peer-review
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Antidepressive lægemidler: nu i 3D
Andersen, J., Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, Dec 2010, In: Lægemiddelforskning. 2010, p. 25-27Research output: Contribution to journal › Journal article › Communication
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Location of the antidepressant binding site in the serotonin transporter: importance of SER-438 in recognition of citalopram and tricyclic antidepressants
Andersen, J., Taboureau, O., Hansen, K. B., Olsen, L., Egebjerg, J., Strømgaard, Kristian & Kristensen, Anders Skov, 2009, In: Journal of Biological Chemistry. 284, 15, p. 10276-10284Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters
Andersen, J., Stuhr-Hansen, N., Zachariassen, L., Toubro, S., Hansen, S. M. R., Eildal, J. N. N., Bond, A. D., Bøgesø, K. P., Bang-Andersen, B., Kristensen, Anders Skov & Strømgaard, Kristian, 19 Jul 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 29, p. 12137-12142Research output: Contribution to journal › Journal article › Research › peer-review
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Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters
Andersen, J., Kristensen, Anders Skov, Bang-Andersen, B. & Strømgaard, Kristian, 2009, In: Chemical Communications. 25, p. 3677-3692Research output: Contribution to journal › Journal article › Research › peer-review
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Structure and absolute configuration of ginkgolide B characterized by IR- and VCD spectroscopy
Andersen, N. H., Christensen, Niels Johan, Lassen, P. R., Freedman, T. B. N., Nafie, L. A., Strømgaard, Kristian & Hemmingsen, Lars Bo Stegeager, 2010, In: Chirality. 22, 2, p. 217-223 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Uncompetitive antagonism of AMPA receptors: Mechanistic insights from studies of polyamine toxin derivatives
Andersen, T. F., Tikhonov, D. B., Bølcho, U., Bolshakov, K., Nelson, J. K., Pluteanu, F., Mellor, I. R., Egebjerg, J. & Strømgaard, Kristian, 7 Sep 2006, In: Journal of Medicinal Chemistry. 49, 18, p. 5414-5423 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist
Andersen, T. F., Vogensen, S. B., Jensen, L. S., Knapp, K. M. & Strømgaard, Kristian, 1 Sep 2005, In: Bioorganic & Medicinal Chemistry. 13, 17, p. 5104-5112 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rational design of a-conotoxin analogues targeting a7 nicotinic acetylcholine receptors: Improved antagonistic activity by incorporation of proline derivatives
Armishaw, C., Jensen, Anders A., Balle, T., Clark, R. J., Harpsøe, Kasper, Skonberg, C., Liljefors, T. & Strømgaard, Kristian, 2009, In: Journal of Biological Chemistry. 284, 14, p. 9498-9512Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and biological activity of novel a-conotoxin analogues incorporating substituted proline derivatives
Armishaw, C., Jensen, Anders A., Skonberg, C., Liljefors, T. & Strømgaard, Kristian, 2009, Peptides for youth: The proceedings of the 20th American peptide symposium. Del Valle, S., Escher, E. & Lubell, W. D. (eds.). Springer, Vol. 611. p. 179-180 (Advances in Experimental Medicine and Biology, Vol. 611).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Improving the stability of alpha-conotoxin AuIB through N-to-C cyclization: The effect of linker length on stability and activity at nicotinic acetylcholine receptors
Armishaw, C. J., Jensen, Anders A., Balle, L. D., Scott, K. C. M., Sørensen, L. & Strømgaard, Kristian, 2011, In: Antioxidants & Redox Signaling. 14, 1, p. 65-76Research output: Contribution to journal › Journal article › Research › peer-review
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Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction
Bach, Anders, Chi, C. N., Pang, G. F., Olsen, L., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 51, p. 9685-9689Research output: Contribution to journal › Journal article › Research › peer-review
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Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction
Bach, Anders, Chi, C. N., Olsen, T. B., Pedersen, S. W., Røder, M. U., Pang, G. F., Clausen, Rasmus Prætorius, Jemth, P. & Strømgaard, Kristian, 2008, In: Journal of Medicinal Chemistry. 51, 20, p. 6450-6459Research output: Contribution to journal › Journal article › Research › peer-review
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Expedient synthesis of 1,3-substituted benzene peptidomimetics
Bach, Anders & Strømgaard, Kristian, 8 Feb 2011, In: Synthesis. 2011, 5, p. 807-815Research output: Contribution to journal › Journal article › Research › peer-review
- Submitted
High-affinity, dimeric inhibitors of PSD-95 as efficient neuroprotectants against ischemic brain damage and for treatment of pain
Bach, Anders & Strømgaard, Kristian, 2012, (Submitted) Patent No. WO2012/156308 (Granted: EP2707014B1; US9139615B2)Research output: Patent
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Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction
Bach, Anders & Strømgaard, Kristian, 14 Jan 2010, Patent No. WO2010/004003 (Granted: EP2320927B1; US9241967B2)Research output: Patent
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Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1
Bach, Anders, Stuhr-Hansen, N., Thorsen, T. S., Bork, N., Moreira, I. S., Frydenvang, Karla Andrea, Padrah, S., Christensen, Søren Brøgger, Madsen, Kenneth Lindegaard, Weinstein, H., Gether, Ulrik & Strømgaard, Kristian, 2010, In: Organic & Biomolecular Chemistry. 8, 19, p. 4281-4288 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein-protein interaktion: et nyt mål for udvikling af lægemidler
Bach, Anders, Gottschalk, M., Kristensen, Anders Skov & Strømgaard, Kristian, 2008, In: Lægemiddelforskning. p. 10-12Research output: Contribution to journal › Journal article › Communication
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Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction
Bach, Anders, Eildal, J. N. N., Stuhr-Hansen, N., Deeskamp, R., Gottschalk, M., Pedersen, S. W., Kristensen, Anders Skov & Strømgaard, Kristian, 10 Mar 2011, In: Journal of Medicinal Chemistry. 54, 5, p. 1333-1346Research output: Contribution to journal › Journal article › Research › peer-review
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A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage
Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322Research output: Contribution to journal › Journal article › Research › peer-review
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Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata
Barslund, A. F., Poulsen, Mette Homann, Bach, T. B., Lucas, S., Kristensen, Anders Skov & Strømgaard, Kristian, 2011, In: Journal of Natural Products. 74, 3, p. 483-486Research output: Contribution to journal › Journal article › Research › peer-review
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Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors
Brier, T. J., Mellor, I. R., Tikhonov, D. B., Neagoe, I., Shao, Z., Brierley, M. J., Strømgaard, Kristian, Jaroszewski, J. W., Krogsgaard-Larsen, Povl & Usherwood, P. N. R., Oct 2003, In: Molecular Pharmacology. 64, 4, p. 954-964 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A sequential binding mechanism in a PDZ domain
Chi, C. N., Bach, Anders, Engström, Å., Wang, H., Strømgaard, Kristian, Gianni, S. & Jemth, P., 2009, In: Biochemistry. 48, 30, p. 7089-7097Research output: Contribution to journal › Journal article › Research › peer-review
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Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example
Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In: Journal of Biological Chemistry. 285, 36, p. 28252-28260Research output: Contribution to journal › Journal article › Research › peer-review
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Ligand binding by PDZ domains
Chi, C. N., Bach, Anders, Strømgaard, Kristian, Gianni, S. & Jemth, P., 2012, In: BioFactors. 38, 5, p. 338-348 (Review) 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302559
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
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