Kristian Helin

Kristian Helin

professor, group leader


  1. 2020
  2. E-pub ahead of print
  3. E-pub ahead of print

    Mutant FOXL2C134W highjacks SMAD4 and SMAD2/3 to drive adult granulosa cell tumors

    Weis-Banke, S. E., Lerdrup, Mads, Kleine-Kohlbrecher, D., Mohammad, F., Sidoli, S., Jensen, O. N., Yanase, T., Nakamura, T., Iwase, A., Stylianou, A., Abu-Rustum, N. R., Aghajanian, C., Soslow, R., Da Cruz Paula, A., Koche, R. P., Weigelt, B., Christensen, Jesper, Helin, Kristian & Cloos, Paul, 8 Jul 2020, In : Cancer Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    BTK inhibitors synergize with 5-FU to treat drug-resistant TP53-null colon cancers

    Lavitrano, M., Ianzano, L., Bonomo, S., Cialdella, A., Cerrito, M. G., Pisano, F., Missaglia, C., Giovannoni, R., Romano, G., McLean, C. M., Voest, E. E., D'Amato, F., Noli, B., Ferri, G. L., Agostini, M., Pucciarelli, S., Helin, Kristian, Leone, B. E., Canzonieri, V. & Grassilli, E., Feb 2020, In : Journal of Pathology. 250, 2, p. 134-147 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary

    Kim, S. H., Da Cruz Paula, A., Basili, T., Dopeso, H., Bi, R., Pareja, F., da Silva, E. M., Gularte-Mérida, R., Sun, Z., Fujisawa, S., Smith, C. G., Ferrando, L., Martins Sebastião, A. P., Bykov, Y., Li, A., Silveira, C., Ashley, C. W., Stylianou, A., Selenica, P., Samore, W. R., Jungbluth, A. A., Zamarin, D., Abu-Rustum, N. R., Helin, Kristian, Soslow, R. A., Reis-Filho, J. S., Oliva, E. & Weigelt, B., 2 Jan 2020, In : Nature Communications. 11, 1, p. 44

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

    Sankar, Aditya, Lerdrup, Mads, Manaf, A., Johansen, Jens Vilstrup, Martin Gonzalez, Javier, Helweg-Larsen, Rehannah Borup, Blanshard, R., Klungland, A., Hansen, Klaus, tcg964, tcg964, Dahl, J. A., Helin, Kristian & Hoffmann, Eva, 2020, In : Nature Cell Biology. 22, 4, p. 380-388 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2019
  8. Published

    Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF

    Berest, I., Arnold, C., Reyes-Palomares, A., Palla, G., Rasmussen, K. D., Giles, H., Bruch, P., Huber, W., Dietrich, S., Helin, Kristian & Zaugg, J. B., 3 Dec 2019, In : Cell Reports. 29, 10, p. 3147-3159.e12 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity

    Højfeldt, J. W., Hedehus, Lin, Laugesen, Anne, Tatar, Tülin, Wiehle, L. & Helin, Kristian, 7 Nov 2019, In : Molecular Cell. 76, 3, p. 423-436 12 p., E3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia

    Radzisheuskaya, Aliaksandra, Shliaha, P. V., Grinev, V., Lorenzini, E., Kovalchuk, S., Shlyueva, Daria, Gorshkov, V., Hendrickson, R. C., Jensen, O. N. & Helin, Kristian, Nov 2019, In : Nature Structural & Molecular Biology. 26, 11, p. 999-1012 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2

    Garland, William, Comet, I., Wu, Mengjun, Radzisheuskaya, Aliaksandra, Rib, Leonor, Vitting-Seerup, Kristoffer, Lloret-Llinares, M., Sandelin, Albin Gustav, Helin, Kristian & Jensen, T. H., 2019, In : Cell Reports. 29, 7, p. 1800-1811 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases

    Paroni, G., Bolis, M., Zanetti, A., Ubezio, P., Helin, Kristian, Staller, P., Gerlach, L. O., Fratelli, M., Neve, R. M., Terao, M. & Garattini, E., 2019, In : Oncogene. 38, p. 2675–2689

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 927363