Knud Jørgen Jensen

Knud Jørgen Jensen

Professor

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    ORCID: 0000-0003-3525-5452

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    1. Published

      tN-Ras, Synaptotagmin1 C2Ab, Annexinb12 and Amphiphysin NBAR can Discriminate Spherical from Cylindrical Membrane Curvature

      kpl171, kpl171, Larsen, J., Rosholm, K. R., Pedersenb, S. L., Munch, H. K., Tkach, Vadym, Sakon, J. J., Bjornholm, T., Weninger, K. R., Bendix, Poul Martin, Jensen, Knud Jørgen, Uline, M. J., Hatzakis, Nikos & Stamou, Dimitrios, 2016, In: Biophysical Journal. 110, 3, 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    2. Published

      Y2 receptor agonists

      Vrang, N., Jensen, Knud Jørgen, Pedersen, S. L., Chelur, S. S., Sasikumar, P. G. N., Dhakshinamoorthy, S. & Ramachandra, M., 2009, Patent No. WO2009/080608 A1, 2 Jul 2009

      Research output: Patent

    3. Published

      X-ray crystal structure of a highly functionalized thiophene as a new backbone amide linker for solid-phase peptide synthesis: relationship between crystal structure and reactivity

      Hammershøj, P., Jessing, M., Madsen, A. Ø., Jensen, Knud Jørgen, Christensen, J. B. & Boas, U., 2007, In: International Journal of Peptide Research and Therapeutics. 13, 1-2, p. 209-212 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Videnskabelig usikkerhed i kemi: Hvad er farligt?

      Green, Sara, Emmeche, Claus & Jensen, Knud Jørgen, 2018, In: Aktuel Naturvidenskab. 6, p. 38-41 4 p.

      Research output: Contribution to journal › Journal article › Communication

    5. Published

      Ultrasmall TPGS-PLGA Hybrid Nanoparticles for Site-Specific Delivery of Antibiotics into Pseudomonas aeruginosa Biofilms in Lungs

      Wan, F., Bohr, S. S. R., Kłodzińska, S. N., Jumaa, H., Huang, Z., Nylander, T., Thygesen, Mikkel Boas, Sørensen, K. K., Jensen, Knud Jørgen, Sternberg, C., Hatzakis, Nikos & Nielsen, Hanne Mørck, 2020, In: ACS Applied Materials and Interfaces. 12, p. 380-389

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Ultramild protein-mediated click chemistry creates efficient oligonucleotide probes for targeting and detecting nucleic acids

      Nåbo, L. J., Madsen, C. S., Jensen, Knud Jørgen, Kongsted, J. & Astakhova, K., 2015, In: ChemBioChem. 16, 8, p. 1163-1167 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Two dialkoxynaphthalene aldehydes as backbone amide linkers for solid-phase synthesis

      Boas, U., Christensen, Jørn Bolstad & Jensen, Knud Jørgen, 2004, In: Journal of Combinatorial Chemistry. 6, 4, p. 497-503 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Total synthesis of desB30 insulin analogues by biomimetic folding of single-chain precursors

      Shelton, A. P. T., Jensen, Knud Jørgen, Schäffer, L. & Hoeg-Jensen, T., 2008, In: ChemBioChem. 9, 18, p. 2989-2996 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Total chemical synthesis of insulin via biomimetic disulfide pairing and folding

      Tofteng, A. P., Jensen, Knud Jørgen & Hoeg-Jensen, T., 2007, Ikke angivet. Rolka, K., Rekowski, P. & Silberring, J. (eds.). Kenes International, Vol. 29. p. 566-567 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

    10. Published

      Thiophene backbone amide linkers, a new class of easily prepared and highly acid-labile linkers for solid-phase synthesis

      Jessing, M., Brandt, M., Jensen, Knud Jørgen, Christensen, Jørn Bolstad & Boas, U., 2006, In: Journal of Organic Chemistry. 71, 18, p. 6734-6741 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      The ¤ortho Backbone Amide Lnker (o-BAL) is an easily prepared and highly acid-labile handle for solid-phase synthesis

      Boas, U., Brask, J., Christensen, J. B. & Jensen, Knud Jørgen, 2002, In: Journal of combinational chemistry. 4, p. 223-228 636 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      The road to the first, fully active and more stable human insulin variant with an additional disulfide bond

      Vinther, T. N., Kjeldsen, T. B., Jensen, Knud Jørgen & Hubálek, F., 2015, In: Journal of Peptide Science. 21, 11, p. 797-806 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    13. Published

      The notion of interpretation in chemistry

      Jensen, Knud Jørgen, 2008, Aspects of philosophy of chemistry. Jensen, K. J. & Nielsen, A. K. (eds.). Nyt Teknisk Forlag, p. 89-106 18 p. (Historical-chemical publications; No. 17).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

    14. Published

      The binding mechanism of a peptidic cyclic serine protease inhibitor

      Jiang, L., Svane, A. S. P., Sørensen, H. P., Jensen, J. K., Hosseini, M., Chen, Z., Weydert, C., Nielsen, J. T., Christensen, A., Yuan, C., Jensen, Knud Jørgen, Nielsen, N. C., Malmendal, A., Huang, M. & Andreasen, P., 2011, In: Journal of Molecular Biology. 412, 2, p. 235-250 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      The ABC of Insulin: The Organic Chemistry of a Small Protein

      Østergaard, M., Mishra, N. K. & Jensen, Knud Jørgen, 2020, In: Chemistry: A European Journal. 26, 38, p. 8341-8357 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

    16. Published

      THAL, a sterically unhindered linker for the solid-phase synthesis of acid-sensitive protected peptide acids

      Isidro-Llobet, A., Boas, U., Jensen, Knud Jørgen, Álvarez, M. & Albericio, F., 2008, In: Journal of Organic Chemistry. 73, 18, p. 7342-7344 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Synthesis of two D-glucosamine derived 3,4-epoxides as potential scaffolds for combinatorial chemistry

      Svejgaard, L., Fuglsang, H., Jensen, P. B., Kelly, N. M., Pedersen, H., Andersen, K., Ruhland, T. & Jensen, Knud Jørgen, 2003, In: Journal of Carbohydrate Chemistry. 22, 3/4, p. 179-184 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Synthesis of peptide thioesters by masking as trithioortho esters in a Fmoe backbone amide linker (BAL) strategy

      Brask, J., Albericio, F. & Jensen, Knud Jørgen, 2004, Ikke angivet. Michael Chorev, T. K. S. (ed.). American Peptide Society, p. 125-126 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

    19. Published

      Synthesis of functionalized de novo designed 8-16 kDa model proteins towards metal ion-binding and esterase activity

      Tofteng, A. P., Hansen, Thomas Hesselhøj, Brask, J., Nielsen, J., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2007, In: Organic & Biomolecular Chemistry. 5, 14, p. 2225-2233 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Synthesis of benzaldehyde-functionalized glycans: a novel approach towards glyco-SAMs as a tool for surface plasmon resonance studies

      Kopitzki, S., Jensen, Knud Jørgen & Thiem, J., 2010, In: Chemistry: A European Journal. 16, 23, p. 7017-7029 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Synthesis of N-methylated peptides: on-resin methylation and microwave-assisted couplings

      Roodbeen, R. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 141-149 9 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    22. Published

      Synthesis of C-terminal peptide thioesters using Fmoc-based solid-phase peptide chemistry

      Shelton, A. P. T. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 119-129 11 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    23. Published

      Synthesis of N,N,N-trimethyl chitosan homopolymer and highly substituted N-alkyl-N,N-dimethyl chitosan derivatives with the aid of di-tert-butyldimethylsilyl chitosan

      Benediktsdóttir, B. E., Gaware, V. S., Rúnarsson, Ö. V., Jónsdóttir, S., Jensen, Knud Jørgen & Másson, M., 2011, In: Carbohydrate Polymers. 86, 4, p. 1451–1460 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Synthesis of 2-acetamido-2-deoxy- beta-D-glucopyranose O-glycopeptides from N-dithiasuccinoyl-protected derivatives

      Jensen, Knud Jørgen, Hansen, Paul Robert, Venugopal, D. & Barany, G., 1996, In: Journal of the American Chemical Society. 118, 13, p. 3148-3155 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Synthesis and evaluation of novel lipidated neuromedin U analogs with increased stability and effects on food intake

      Dalbøge, L. S., Pedersen, S. L., van Witteloostuijn, S. B., Rasmussen, J. E., Rigbolt, K. T. G., Jensen, Knud Jørgen, Holst, B., Vrang, N. & Jelsing, J., 2015, In: Journal of Peptide Science. 21, 2, p. 85-94 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Synthesis and Characterization of Adamantane-Containing Heteropeptides with a Chirality Switch

      Aloisi, A., Christensen, Niels Johan, Sorensen, K. K., Guilbaud-Chereau, C., Jensen, Knud Jørgen & Bianco, A., 2020, In: European Journal of Organic Chemistry. 2020, 7, p. 815-820

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Synergy of Two Highly Specific Biomolecular Recognition Events: Aligning an AT-Hook Peptide in DNA Minor Grooves via Covalent Conjugation to 2′-Amino-LNA

      Ejlersen, M., Christensen, Niels Johan, Sørensen, K. K., Jensen, Knud Jørgen, Wengel, J. & Lou, C., 2018, In: Bioconjugate Chemistry. 29, p. 1025-1029 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Synergy of Liquid Ordered "Raft Like" Domains and Membrane Curvature in Promoting Sorting of Lipidated Proteins Such As NRas

      Hatzakis, Nikos, Larsen, J. K., Jensen, M. B., Bhatia, V. K., Pedersen, S. L., Jensen, Knud Jørgen & Stamou, Dimitrios, 2012, In: Biophysical Journal. 102, 3 Supplement 1, p. 18a-19a 2 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    29. Published

      Synchrotron radiation circular dichroism spectroscopy applied to metmyoglobin and a 4-a-helix bundle carboprotein

      Thulstrup, Peter Waaben, Brask, J., Jensen, Knud Jørgen & Larsen, Erik, 2005, In: Biopolymers. 78, p. 46-52 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Steric effects in release of amides from linkers in solid-phase synthesis: molecular mechanics modeling of key step in peptide and combinatorial chemistry

      Norrby, P. & Jensen, Knud Jørgen, 2006, In: International Journal of Peptide Research and Therapeutics. 12, 4, p. 335-339 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Sorting of tN-Ras by Membrane Curvature in Lipid Vesicles and Tubes

      Rosholm, K. R., Larsen, J., Pedersen, S. L., Munch, H. K., Jensen, Knud Jørgen, Hatzakis, Nikos & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, Supplement 1, p. 549A 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    32. Published

      Solid-supported enzymatic synthesis of pectic oligogalacturonides and their analysis by MALDI-TOF mass spectrometry

      Guillaumie, F., Sterling, J. D., Jensen, Knud Jørgen, Thomas, O. R. T. & Mohnen, D., 2003, In: Carbohydrate Research. 338, 19, p. 1951-1960 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Solid-phase synthesis of phosphopeptides

      Højlys-Larsen, K. B. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 191-199 9 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    34. Published

      Solid-phase synthesis of new saphenamycin analogues with antimicrobial activity

      Laursen, J. B., De Visser, P. C., Nielsen, H. K., Jensen, Knud Jørgen & Nielsen, J., 21 Jan 2002, In: Bioorganic and Medicinal Chemistry Letters. 12, 2, p. 171-175 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Solid-phase synthesis of O-glycopeptides from N-dithiasuccinoyl-protected D-glucosamine derivatives

      Hansen, Paul Robert, Jensen, Knud Jørgen & Barany, G., 1995, In: Peptides. 1994, p. 729-730 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Solid-phase peptide synthesis as an enabling tool for proteomics

      Larsen, K., Brandt, M., Sørensen, K. K., Gammeltoft, S. & Jensen, Knud Jørgen, 2007, In: Chimica Oggi – Chemistry Today. 25, 3, p. 34-36 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Solid-phase peptide synthesis: an introduction

      Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 1-21 21 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    38. Published

      Solid-phase glycopeptide synthesis of tyrosine-glycosylated glycogenin fragments as substrates for glucosylation by glycogenin

      Jansson, A. M., Jensen, Knud Jørgen, Meldal, M., Lomako, J., Lomako, W. M., Olsen, C. E. & Bock, K., 1996, In: Journal of the Chemical Society - Perkin transactions 1. 1996, p. 1001-1006 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Solid-phase chemical tools for glycobiology: perspective

      Larsen, K., Thygesen, Mikkel Boas, Guillaumie, F., Willats, W. G. T. & Jensen, Knud Jørgen, 2006, In: Carbohydrate Research. 341, 10, p. 1209-1234 26 p.

      Research output: Contribution to journal › Review › Research › peer-review

    40. Published

      Softening of POPC membranes by magainin

      Bouvrais, H., Méléard, P., Pott, T., Jensen, Knud Jørgen, Brask, J. & Ipsen, J. H., 2008, In: Biophysical Chemistry. 137, 1, p. 7-12 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Small-molecule affinity ligands for protein purification: combined computational enrichment and automated in-line screeing of an optically encoded library

      Rasmussen, J. E., Schiødt, C. B., Christensen, S. F., Nørskov-Lauritsen, L., Meldal, M., St. Hilaire, P. M. & Jensen, Knud Jørgen, 2010, In: Angewandte Chemie - International Edition. 49, 20, p. 3477-3480 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Site-selective three-component reaction for dual-functionalization of peptides

      Munch, H. K., Rasmussen, J. E., Popa, G., Christensen, Jørn Bolstad & Jensen, Knud Jørgen, 2013, In: Chemical Communications. 49, 19, p. 1936-1938 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Shape of de novo designed proteins in solution: small angle x-ray scattering

      Høiberg-Nielsen, R., Tofteng, A. P., Sørensen, K. K., Arleth, Lise & Jensen, Knud Jørgen, 2007, Ikke angivet. Rolka, K., Rekowski, P. & Silberring, J. (eds.). Kenes International, p. 772-773 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

    44. Published

      Semi-automated microwave-assisted SPPS: optimization of protocols and synthesis of difficult sequences

      Pedersen, S. L., Sørensen, K. K. & Jensen, Knud Jørgen, 2010, In: Biopolymers (Peptide Science). 94, 2, p. 206-212 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Self‐Assembly of DNA–Peptide Supermolecules: Coiled‐Coil Peptide Structures Templated by d‐DNA and l-DNA Triplexes Exhibit Chirality‐Independent but Orientation‐Dependent Stabilizing Cooperativity

      Lou, C., Boesen, J. T., Christensen, Niels Johan, Sørensen, K. K., Thulstrup, Peter Waaben, Pedersen, M. N., Giralt, E., Jensen, Knud Jørgen & Wengel, J., 2020, In: Chemistry: A European Journal. 26, 25, p. 5676-5684 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Self-assembly of designed coiled coil peptides studied by small-angle X-ray scattering and analytical ultracentrifugation

      Malik, L., Nygaard, J., Christensen, Niels Johan, Thulstrup, Peter Waaben, Arleth, Lise, Jensen, Knud Jørgen & Streicher, W., 2013, In: Journal of Peptide Science. 19, 5, p. 283-292 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Self-assembling peptides form nanodiscs that stabilize membrane proteins

      Midtgaard, S. R., Pedersen, Martin Cramer, Kirkensgaard, Jacob Judas Kain, Sørensen, K. K., Mortensen, Kell, Jensen, Knud Jørgen & Arleth, Lise, 1 Jan 2014, In: Soft Matter. 10, 5, p. 738-752 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence

      Martos Maldonado, M. C., Hjuler, C. T., Sørensen, K. K., Thygesen, Mikkel Boas, Rasmussen, J. E., Villadsen, K., Midtgaard, S. R., Kol, S., Schoffelen, S. & Jensen, Knud Jørgen, 1 Dec 2018, In: Nature Communications. 9, 13 p., 3307 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Selective Acylation of Proteins at Gly and Lys in His Tags

      Jensen, Knud Jørgen, Thygesen, Mikkel Boas, Sorensen, K. K., Wu, S., Treiberg, Tuule & Schoffelen, S., 2022, In: ChemBioChem. 23, 24, 6 p., 202200359.

      Research output: Contribution to journal › Letter › Research › peer-review

    50. Published

      Selection of high-affinity peptidic serine protease inhibitors with increased binding entropy from a back-flip library of peptide-protease fusions

      Sørensen, H. P., Xu, P., Jiang, L., Kromann-Hansen, T., Jensen, Knud Jørgen, Huang, M. & Andreasen, P. A., 2015, In: Journal of Molecular Biology. 427, 19, p. 3110-3122 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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