Knud Jørgen Jensen

Knud Jørgen Jensen

Professor

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    ORCID: 0000-0003-3525-5452

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    1. Published

      The ABC of Insulin: The Organic Chemistry of a Small Protein

      Østergaard, M., Mishra, N. K. & Jensen, Knud Jørgen, 2020, In: Chemistry: A European Journal. 26, 38, p. 8341-8357 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

    2. Published

      Glycoconjugate Oxime Formation Catalyzed at Neutral pH: Mechanistic Insights and Applications of 1,4-Diaminobenzene as a Superior Catalyst for Complex Carbohydrates

      Østergaard, M., Christensen, Niels Johan, Hjuler, C. T., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2018, In: Bioconjugate Chemistry. 29, 4, p. 1219-1230 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Half-life extension of biopharmaceuticals using chemical methods: alternatives to PEGylation

      van Witteloostuijn, S. B., Pedersen, S. L. & Jensen, Knud Jørgen, 2016, In: ChemMedChem. 11, 22, p. 2474-2495 22 p.

      Research output: Contribution to journal › Review › Research › peer-review

    4. Published

      Neoglycolipids for Prolonging the Effects of Peptides: Self-Assembling Glucagon-like Peptide 1 Analogues with Albumin Binding Properties and Potent in Vivo Efficacy

      van Witteloostuijn, S. B., Mannerstedt, K. M. S., Wismann, P., Bech, E. M., Thygesen, Mikkel Boas, Vrang, N., Jelsing, J., Jensen, Knud Jørgen & Pedersen, S. L., 2017, In: Molecular Pharmaceutics. 14, 1, p. 193-205 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      GUB06-046, a novel secretin/glucagon-like peptide 1 co-agonist, decreases food intake, improves glycemic control, and preserves beta cell mass in diabetic mice

      van Witteloostuijn, S. B., Dalboge, L. S., Hansen, G., Midtgaard, S. R., Jensen, G. V., Jensen, Knud Jørgen, Vrang, N., Jelsing, J. & Pedersen, S. L., 2017, In: Journal of Peptide Science. 23, 12, p. 845-854 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility

      Zhao, B., Xu, P., Jiang, L., Jensen, B. P., Kromann-Hansen, T., Jensen, J. K., Sorensen, H. P., Liu, Z., Nielsen, J. T., Christensen, A., Hosseini, M., Sørensen, K. K., Nielsen, N. C., Jensen, Knud Jørgen, Huang, M. & Andreasen, P., 2014, In: PLOS ONE. 9, 12, 27 p., e115872.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      A brain-targeting lipidated peptide for neutralizing RNA-mediated toxicity in Polyglutamine Diseases

      Zhang, Q., Yang, M., Sørensen, K. K., Madsen, C. S., Boesen, J. T., An, Y., Peng, S. H., Wei, Y., Wang, Q., Jensen, Knud Jørgen, Zuo, Z., Chan, H. Y. E. & Ngo, J. C. K., 2017, In: Scientific Reports. 7, 1, 13 p., 12077.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Brain-Targeting Delivery of Two Peptidylic Inhibitors for Their Combination Therapy in Transgenic Polyglutamine Disease Mice via Intranasal Administration

      Yang, M., Zhang, Q., Wang, Q., Sørensen, K. K., Boesen, J. T., Ma, S. Y., Jensen, Knud Jørgen, Kwan, K. M., Ngo, J. C. K., Chan, H. Y. E. & Zuo, Z., 2018, In: Molecular Pharmaceutics. 15, 12, p. 5781-5792 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Ca2+-Responsive Glyco-insulin

      Wu, S., Østergaard, M., Fredholt, Freja, Christensen, Niels Johan, Sørensen, K. K., Mishra, N. K., Nielsen, Hanne Mørck & Jensen, Knud Jørgen, 2023, In: Bioconjugate Chemistry. 34, 3, p. 518–528

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      4,6-O-benzylidene directed ß-mannosylation without intermediate triflate formation? Comparison of trichloroacetimidate and DISAL donors in microwave-promoted glycosylations under neutral conditions

      Worm-Leonhard, K., Larsen, K. & Jensen, Knud Jørgen, 2007, In: Journal of Carbohydrate Chemistry. 26, 7, p. 349-368 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase

      Wong, M. M. J. E., Midtgaard, S. R., Gysel, K., Thygesen, Mikkel Boas, Sørensen, K. K., Jensen, Knud Jørgen, Stougaard, J., Thirup, S. S. & Blaise, M., 2015, In: Acta Crystallographica. Section D: Biological Crystallography. 71, p. 592-605 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Ultrasmall TPGS-PLGA Hybrid Nanoparticles for Site-Specific Delivery of Antibiotics into Pseudomonas aeruginosa Biofilms in Lungs

      Wan, F., Bohr, S. S. R., Kłodzińska, S. N., Jumaa, H., Huang, Z., Nylander, T., Thygesen, Mikkel Boas, Sørensen, K. K., Jensen, Knud Jørgen, Sternberg, C., Hatzakis, Nikos & Nielsen, Hanne Mørck, 2020, In: ACS Applied Materials and Interfaces. 12, p. 380-389

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Hierarchical self-assembly of designed 2 x 2-a-helix bundle proteins on Au(111) surfaces

      Wackerbarth, H., Tofteng, A. P., Jensen, Knud Jørgen, Chorkendorff, I. & Ulstrup, J., 2006, In: Langmuir. 22, p. 6661-6667 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Y2 receptor agonists

      Vrang, N., Jensen, Knud Jørgen, Pedersen, S. L., Chelur, S. S., Sasikumar, P. G. N., Dhakshinamoorthy, S. & Ramachandra, M., 2009, Patent No. WO2009/080608 A1, 2 Jul 2009

      Research output: Patent

    15. Published

      Insulin analog with additional disulfide bond has increased stability and preserved activity

      Vinther, T. N., Norrman, M., Ribel, U., Huus, K., Schlein, M., Steensgaard, D. B., Pedersen, T. Å., Pettersson, I., Ludvigsen, S., Kjeldsen, T., Jensen, Knud Jørgen & Hubálek, F., 2013, In: Protein Science. 22, 3, p. 296-305 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization

      Vinther, T. N., Norrman, M., Strauss, H. M., Huus, K., Schlein, M., Pedersen, T. Å., Kjeldsen, T., Jensen, Knud Jørgen & Hubálek, F., 2012, In: P L o S One. 7, 2, 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      The road to the first, fully active and more stable human insulin variant with an additional disulfide bond

      Vinther, T. N., Kjeldsen, T. B., Jensen, Knud Jørgen & Hubálek, F., 2015, In: Journal of Peptide Science. 21, 11, p. 797-806 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    18. Published

      Identification of anchor points for chemical modification of a small cysteine-rich protein by using a cysteine scan

      Vinther, T. N., Ribel, U., Pedersen, T. Å., Kjeldsen, T. B., Jensen, Knud Jørgen & Hubálek, F., 2011, In: ChemBioChem. 12, 16, p. 2448–2455 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Additional disulfide bonds in insulin: prediction, recombinant expression, receptor binding affinity, and stability

      Vinther, T. N., Pettersson, I., Huus, K., Schlein, M., Steensgaard, D. B., Sørensen, A., Jensen, Knud Jørgen, Kjeldsen, T. & Hubalek, F., 2015, In: Protein Science. 24, 5, p. 779-788 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Inside Cover: Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates

      Villadsen, K., Martos Maldonado, M. C., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2017, In: ChemBioChem. 18, 7, p. 573 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates

      Villadsen, K., Martos Maldonado, M. C., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2017, In: ChemBioChem. 18, 7, p. 574-612 39 p.

      Research output: Contribution to journal › Review › Research › peer-review

    22. Published

      Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

      Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Predictive mutagenesis of ligation-independent cloning (LIC) vectors for protein expression and site-specific chemical conjugation

      Vernet, E., Sauer, J., Andersen, P. A., Jensen, Knud Jørgen & Voldborg, B. G. R., 2011, In: Analytical Biochemistry. 414, 2, p. 312-314 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Total chemical synthesis of insulin via biomimetic disulfide pairing and folding

      Tofteng, A. P., Jensen, Knud Jørgen & Hoeg-Jensen, T., 2007, Ikke angivet. Rolka, K., Rekowski, P. & Silberring, J. (eds.). Kenes International, Vol. 29. p. 566-567 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

    25. Published

      Synthesis of functionalized de novo designed 8-16 kDa model proteins towards metal ion-binding and esterase activity

      Tofteng, A. P., Hansen, Thomas Hesselhøj, Brask, J., Nielsen, J., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2007, In: Organic & Biomolecular Chemistry. 5, 14, p. 2225-2233 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Peptide dithiodiethanol esters for in situ generation of thioesters for use in native ligation

      Tofteng, A. P., Jensen, Knud Jørgen & Hoeg-Jensen, T., 2007, In: Tetrahedron Letters. 48, 12, p. 2105-2107 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Peptides on nanoparticles: linkers for chemoselective, biocompatible immobilization

      Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2007, In: Journal of Peptide Science. 88, 4, p. 616 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    28. Published

      Peptides on nanoparticles: linkers for chemoselective, biocompatible immobilization

      Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2007. 1 p.

      Research output: Contribution to conference › Poster › Research

    29. Published

      Chemoselectivity and Glyconanoparticles

      Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2011, Petite and sweet: Glyco-nanotechnology as a bridge to new medicines. American Chemical Society, p. 37-48 12 p. (A C S Symposium Series, Vol. 1091).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    30. Published

      Nucleophilic catalysis of carbohydrate oxime formation by anilines

      Thygesen, Mikkel Boas, Munch, H. K., Sauer, J., Cló, E., Jørgensen, M. R., Hindsgaul, O. & Jensen, Knud Jørgen, 2010, In: Journal of Organic Chemistry. 75, 5, p. 1752-1755 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Chemoselective capture of glycans for analysis on gold nanoparticles: carbohydrate oxime tautomers provide functional recognition by proteins

      Thygesen, Mikkel Boas, Sauer, J. & Jensen, Knud Jørgen, 2009, In: Chemistry: A European Journal. 15, 7, p. 1949-1960 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Direct chemoselective synthesis of glyconanoparticles from unprotected reducing glycans and glycopeptide aldehydes

      Thygesen, Mikkel Boas, Sørensen, K. K., Cló, E. & Jensen, Knud Jørgen, Nov 2009, In: Chemical Communications. 42, p. 6367-9 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Carbohydrate-modified gold nanoparticles

      Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2016, Carbohydrate nanotechnology. J. Stine, K. (ed.). Wiley, p. 79-98

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    34. Published

      Synchrotron radiation circular dichroism spectroscopy applied to metmyoglobin and a 4-a-helix bundle carboprotein

      Thulstrup, Peter Waaben, Brask, J., Jensen, Knud Jørgen & Larsen, Erik, 2005, In: Biopolymers. 78, p. 46-52 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

      Taskova, M., Madsen, C. S., Jensen, Knud Jørgen, Hansen, L. H., Vester, B. & Astakhova, K., 2017, In: Bioconjugate Chemistry. 28, 3, p. 768-774 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Chemically synthesized 58-mer LysM domain binds lipochitin oligosaccharide

      Sørensen, K. K., Simonsen, J. B., Maolanon, N. N., Stougaard, J. & Jensen, Knud Jørgen, 2014, In: ChemBioChem. 15, 14, p. 2097-2105 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      High‐Performance Reversed‐Phase Flash Chromatography Purification of Peptides and Chemically Modified Insulins

      Sørensen, K. K., Mishra, N. K., Paprocki, M. P., Mehrotra, A. & Jensen, Knud Jørgen, 2021, In: ChemBioChem. 22, 10, p. 1818–1822

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Selection of high-affinity peptidic serine protease inhibitors with increased binding entropy from a back-flip library of peptide-protease fusions

      Sørensen, H. P., Xu, P., Jiang, L., Kromann-Hansen, T., Jensen, Knud Jørgen, Huang, M. & Andreasen, P. A., 2015, In: Journal of Molecular Biology. 427, 19, p. 3110-3122 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Synthesis of two D-glucosamine derived 3,4-epoxides as potential scaffolds for combinatorial chemistry

      Svejgaard, L., Fuglsang, H., Jensen, P. B., Kelly, N. M., Pedersen, H., Andersen, K., Ruhland, T. & Jensen, Knud Jørgen, 2003, In: Journal of Carbohydrate Chemistry. 22, 3/4, p. 179-184 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      COMU: scope and limitations of the latest innovation in peptide acyl transfer reagents

      Subirós-Funosas, R., Nieto-Rodriguez, L., Jensen, Knud Jørgen & Albericio, F., 2013, In: Journal of Peptide Science. 19, 7, p. 408-414 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Characterization of an immunodominant cancer-specific O-glycopeptide epitope in murine podoplanin (OTS8)

      Steentoft, C., Schjoldager, Katrine Ter-Borch Gram, Cló, E., Mandel, Ulla, Levery, S. B., Pedersen, J. W., Jensen, Knud Jørgen, Blixt, O. & Clausen, Henrik, 2010, In: Glycoconjugate Journal. 27, 6, p. 571-82 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Effect of residual water and microwave heating on half-lifes of reagents and reactive intermediates in peptide synthesis

      Shelton, A. P. T., Pedersen, S. L., Stærk, Dan & Jensen, Knud Jørgen, 2012, In: Chemistry: A European Journal. 18, 29, p. 9024-9031 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Fmoc solid-phase synthesis of C-terminal peptide thioesters by formation of a backbone pyroglutamyl imide moiety

      Shelton, A. P. T., Sørensen, K. K., Conde-Frieboes, K. W., Hoeg-Jensen, T. & Jensen, Knud Jørgen, 2009, In: Angewandte Chemie - International Edition. 48, 40, p. 7411-7414 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Total synthesis of desB30 insulin analogues by biomimetic folding of single-chain precursors

      Shelton, A. P. T., Jensen, Knud Jørgen, Schäffer, L. & Hoeg-Jensen, T., 2008, In: ChemBioChem. 9, 18, p. 2989-2996 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Linkers, resins, and general procedures for solid-phase peptide synthesis

      Shelton, A. P. T. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 23-41 19 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    46. Published

      Synthesis of C-terminal peptide thioesters using Fmoc-based solid-phase peptide chemistry

      Shelton, A. P. T. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 119-129 11 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    47. Published

      Backbone amide linker strategy: protocols for the synthesis of C-terminal peptide aldehydes

      Shelton, A. P. T. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 131-139 9 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    48. Published

      Kinetic analysis of inhibition of glucoamylase and active site mutants via chemoselective oxime immobilization of acarbose on SPR chip surfaces

      Sauer, J., Abou Hachem, M., Svensson, B., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2013, In: Carbohydrate Research. 375, p. 21-28 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Impact of chain length on antibacterial activity and hemocompatibility of quaternary N-alkyl and N,N-dialkyl chitosan derivatives

      Sahariah, P., Benediktssdóttir, B. E., Hjálmarsdóttir, M. Á., Sigurjonsson, O. E., Sørensen, K. K., Thygesen, Mikkel Boas, Jensen, Knud Jørgen & Másson, M., 2015, In: Biomacromolecules. 16, 5, p. 1449-1460 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Antimicrobial peptide shows enhanced activity and reduced toxicity upon grafting to chitosan polymers

      Sahariah, P., Sørensen, K. K., Hjálmarsdóttir, M. Á., Sigurjónsson, Ó. E., Jensen, Knud Jørgen, Másson, M. & Thygesen, Mikkel Boas, 2015, In: Chemical Communications. 51, 58, p. 11611-11614 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Bioconjugation of a Near-Infrared DNA-Stabilized Silver Nanocluster to Peptides and Human Insulin by Copper-Free Click Chemistry

      Rück, Vanessa, Mishra, N. K., Sørensen, K. K., Liisberg, M. B., Sloth, Ane Beth, Cerretani, Cecilia, Mollerup, Christian Brinch, Kjær, Andreas, Lou, C., Jensen, Knud Jørgen & Vosch, Tom, 2023, In: Journal of the American Chemical Society. 145, 30, p. 16771–16777 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Farnesylated peptides in model membranes: a biophysical investigation

      Rowat, A. C., Brask, J., Sparrman, T., Jensen, Knud Jørgen, Lindblom, G. & Ipsen, J. H., 2004, In: European Biophysics Journal. 33, 6, p. 300-309 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells

      Rosholm, K. R., Leijnse, Natascha, Mantsiou, A., Tkach, Vadym, Pedersen, S. L., Wirth, V. F., Oddershede, L. B., Jensen, Knud Jørgen, Martinez, Karen Laurence, Hatzakis, Nikos, Bendix, Poul Martin, Callan-Jones, A. & Stamou, Dimitrios, 8 May 2017, In: Nature Chemical Biology. 13, 7, p. 724-729

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Sorting of tN-Ras by Membrane Curvature in Lipid Vesicles and Tubes

      Rosholm, K. R., Larsen, J., Pedersen, S. L., Munch, H. K., Jensen, Knud Jørgen, Hatzakis, Nikos & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, Supplement 1, p. 549A 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    55. Published

      Secondary structure modifications of serine protease inhibitor upain-1 to improve binding affinity

      Roodbeen, R., Andreasen, P. & Jensen, Knud Jørgen, 2010, Peptides - Copenhagen 2010, tales of peptides: proceedings of the thirty-first European peptide symposium, Copenhagen. Lebl, M., Meldal, M., Jensen, K. J. & Hoeg-Jensen, T. (eds.). European Peptide Society, p. 554-555 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

    56. Published

      Bicyclic peptide inhibitor of urokinase-type plasminogen activator: mode of action

      Roodbeen, R., Jensen, B. P., Jiang, L., Jensen, J. K., Christensen, A., Nielsen, J. T., Huang, M., Mulder, F., Nielsen, N. C., Andreasen, P. & Jensen, Knud Jørgen, 2013, In: ChemBioChem. 14, 16, p. 2179-2188 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Synthesis of N-methylated peptides: on-resin methylation and microwave-assisted couplings

      Roodbeen, R. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 141-149 9 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    58. Published

      Microwave heating in the solid-phase synthesis of N-methylated peptides: when is room temperature better?

      Roodbeen, R., Pedersen, S. L., Hosseini, M. & Jensen, Knud Jørgen, 2012, In: European Journal of Organic Chemistry. 2012, 36, p. 7106-7111 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Linear Multiepitope (Glyco)peptides for Type-Specific Serology of Herpes Simplex Virus (HSV) Infections

      Risinger, C. W., Sørensen, K. K., Jensen, Knud Jørgen, Olofsson, S., Bergström, T. & Blixt, K. O., 2017, In: ACS Infectious Diseases. 3, 5, p. 360-367 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Small-molecule affinity ligands for protein purification: combined computational enrichment and automated in-line screeing of an optically encoded library

      Rasmussen, J. E., Schiødt, C. B., Christensen, S. F., Nørskov-Lauritsen, L., Meldal, M., St. Hilaire, P. M. & Jensen, Knud Jørgen, 2010, In: Angewandte Chemie - International Edition. 49, 20, p. 3477-3480 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Role of the peri-effect in synthesis and reactivity of highly substituted naphthaldehydes: a novel backbone amide linker for solid-phase synthesis

      Pittelkow, M., Boas, U., Jessing, M., Jensen, Knud Jørgen & Christensen, J. B., 2005, In: Organic and Biomolecular Chemistry. 3, 3, p. 508-514 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Phenazines and natural products; novel synthesis of saphenic acid

      Petersen, L., Jensen, Knud Jørgen & Nielsen, J., 1 Jan 1999, In: Synthesis. 10, p. 1763-1766 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      DISAL glycosyl donors for the synthesis of a linear hexasaccharide under mild conditions

      Petersen, L., Laursen, J. B., Larsen, K., Motawie, Mohammed Saddik & Jensen, Knud Jørgen, 2003, In: Organic Letters. 5, 8, p. 1309-1312 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      Improved PET Imaging of uPAR expression using new Cu-64-labeled cross-bridged peptide ligands: comparative in vitro and in vivo studies

      Persson, M., Hosseini, M., Madsen, J., Jørgensen, T. J. D., Jensen, Knud Jørgen, Kjær, Andreas & Ploug, Michael, 2013, In: Theranostics. 3, 9, p. 618-632 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      Glyco-scan: varying glycosylation in the sequence of the peptide hormone PYY3-36 and its effect on receptor selectivity

      Pedersen, S. L., Steentoft, C., Vrang, N. & Jensen, Knud Jørgen, 2010, In: ChemBioChem. 11, 3, p. 366-374 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Peptide release, side-chain deprotection, work-up, and isolation

      Pedersen, S. L. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 43-63 21 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    67. Published

      Peptide hormone isoforms: N-terminally branched PPY3-36 isoforms give improved lipid and fat-cell metabolism in diet-induced obese mice

      Pedersen, S. L., Sasikumar, P. G., Chelur, S., Holst, Birgitte, Artmann, A., Jensen, Knud Jørgen & Vrang, N., 2010, In: Journal of Peptide Science. 16, 11, p. 664-673 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Microwave heating in solid-phase peptide synthesis

      Pedersen, S. L., Shelton, A. P. T., Malik, L. & Jensen, Knud Jørgen, 2012, In: Chemical Society Reviews. 41, 5, p. 1826-1844 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Semi-automated microwave-assisted SPPS: optimization of protocols and synthesis of difficult sequences

      Pedersen, S. L., Sørensen, K. K. & Jensen, Knud Jørgen, 2010, In: Biopolymers (Peptide Science). 94, 2, p. 206-212 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Improving membrane binding as a design strategy for amphipathic peptide hormones: 2-helix variants of PYY3-36

      Pedersen, S. L., Bhatia, V. K., Jurt, S., Paulsson, J. F., Pedersen, M. H., Jørgensen, R., Holst, Birgitte, Stamou, Dimitrios, Vrang, N., Zerbe, O. & Jensen, Knud Jørgen, 2012, In: Journal of Peptide Science. 18, 9, p. 579-587 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Modifying the conserved C-terminal tyrosine of the peptide hormone PYY3-36 to improve Y2 receptor selectivity

      Pedersen, S. L., Holst, Birgitte, Vrang, N. & Jensen, Knud Jørgen, 2009, In: Journal of Peptide Science. 15, 11, p. 753-759 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      Automated microwave-assisted peptide synthesis with a novel robotic synthesizer: synthesis of difficult sequences

      Pedersen, S. L., Mehrotra, A. & Jensen, Knud Jørgen, 2010, Peptides - Copenhagen 2010, tales of peptides: proceedings of the thirty-first European peptide symposium, Copenhagen. Lebl, M., Meldal, M., Jensen, K. J. & Hoeg-Jensen, T. (eds.). European Peptide Society, p. 174-175 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

    73. Published

      Peptide architecture: adding an a-helix to the PYY lysine side chain provides nanomolar binding and body-weight-lowering effects

      Pedersen, S. L., Sasikumar, P. G., Vrang, N. & Jensen, Knud Jørgen, 2010, In: ChemMedChem. 5, 4, 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Instruments for automated peptide synthesis

      Pedersen, S. L. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 215-224 10 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    75. Published

      Safety‐catch linkers for Fmoc solid‐phase synthesis of peptide thioesters and hydrazides by amide‐to‐imide activation

      Paprocki, M. P., Rasmussen, J. E., Sørensen, K. K. & Jensen, Knud Jørgen, 2021, In: Journal of Peptide Science. 27, 12, 6 p., e3364.

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      Chirality transmission in macromolecular domains

      Pandey, S., Mandal, S., Danielsen, M. B., Brown, A., Hu, C., Christensen, Niels Johan, Kulakova, A. V., Song, S., Brown, T., Jensen, Knud Jørgen, Wengel, J., Lou, C. & Mao, H., 2022, In: Nature Communications. 13, 1, 11 p., 76.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      Combinatorial solid-phase synthesis of hapalosin mimetics

      Olsen, J. A., Jensen, Knud Jørgen & Nielsen, J., 1 Mar 2000, In: Journal of Combinatorial Chemistry. 2, 2, p. 143-150 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Ultramild protein-mediated click chemistry creates efficient oligonucleotide probes for targeting and detecting nucleic acids

      Nåbo, L. J., Madsen, C. S., Jensen, Knud Jørgen, Kongsted, J. & Astakhova, K., 2015, In: ChemBioChem. 16, 8, p. 1163-1167 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Metal ion controlled self-assembly of a chemically reengineered protein drug studied by small-angle X-ray scattering

      Nygaard, J., Munch, H. K., Thulstrup, Peter Waaben, Christensen, Niels Johan, Høeg-Jensen, T., Jensen, Knud Jørgen & Arleth, Lise, 2012, In: Langmuir. 28, 33, p. 12159-12170 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      Steric effects in release of amides from linkers in solid-phase synthesis: molecular mechanics modeling of key step in peptide and combinatorial chemistry

      Norrby, P. & Jensen, Knud Jørgen, 2006, In: International Journal of Peptide Research and Therapeutics. 12, 4, p. 335-339 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Epidermal LysM receptor ensures robust symbiotic signalling in Lotus japonicus

      Murakami, E., Cheng, J., Gysel, K., Bozsoki, Z., Kawaharada, Y., Hjuler, C. T., Sørensen, K. K., Tao, K., Kelly, S., Venice, F., Genre, A., Thygesen, M. B., de Jong, N., Vinther, M., Jensen, D. B., Jensen, K. J., Blaise, M., Madsen, L. H., Andersen, K. R., Stougaard, J. & 1 others, Radutoiu, S., 2018, In: eLife. 7, 21 p., e33506.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      Site-selective three-component reaction for dual-functionalization of peptides

      Munch, H. K., Rasmussen, J. E., Popa, G., Christensen, Jørn Bolstad & Jensen, Knud Jørgen, 2013, In: Chemical Communications. 49, 19, p. 1936-1938 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Metal-Ion Directed Self-Assembly of Insulin Derivatives

      Munch, H. K., Heide, S. T., Christensen, Niels Johan, Høeg-Jensen, T., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2010, In: Journal of Peptide Science. S2

      Research output: Contribution to journal › Conference abstract in journal › Research

    84. Published

      Construction of insulin 18-mer nanoassemblies driven by coordination to Iron(II) and Zinc(II) ions at distinct sites

      Munch, H. K., Nygård, Jesper, Christensen, Niels Johan, Engelbrekt, C., Østergaard, M., Porsgaard, T., Hoeg-Jensen, T., Zhang, J., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2016, In: Angewandte Chemie International Edition. 55, 7, p. 2378-2381 4 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    85. Published

      Controlled self-assembly of re-engineered insulin by FeII

      Munch, H. K., Heide, S. T., Christensen, Niels Johan, Høeg-Jensen, T., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2011, In: Chemistry: A European Journal. 17, 26, p. 7198-7204 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects

      Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      Self-assembling peptides form nanodiscs that stabilize membrane proteins

      Midtgaard, S. R., Pedersen, Martin Cramer, Kirkensgaard, Jacob Judas Kain, Sørensen, K. K., Mortensen, Kell, Jensen, Knud Jørgen & Arleth, Lise, 1 Jan 2014, In: Soft Matter. 10, 5, p. 738-752 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Gold-ferrocene glyco-nanoparticles for high-sensitivity electrochemical detection of carbohydrate-lectin interactions

      Martos Maldonado, M. C., Thygesen, Mikkel Boas, Jensen, Knud Jørgen & Vargas-Berenguel, A., 2013, In: European Journal of Organic Chemistry. 2013, 14, p. 2793-2801 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence

      Martos Maldonado, M. C., Hjuler, C. T., Sørensen, K. K., Thygesen, Mikkel Boas, Rasmussen, J. E., Villadsen, K., Midtgaard, S. R., Kol, S., Schoffelen, S. & Jensen, Knud Jørgen, 1 Dec 2018, In: Nature Communications. 9, 13 p., 3307 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Lipochitin oligosaccharides immobilized through oximes in glycan microarrays bind LysM proteins

      Maolanon, N. N., Blaise, M., Sørensen, K. K., Thygesen, Mikkel Boas, Clo, E., Sullivan, J. T., Ronson, C. W., Stougaard, J., Blixt, K. O. & Jensen, Knud Jørgen, 2014, In: ChemBioChem. 15, 3, p. 425-434 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      An Aldehyde Responsive, Cleavable Linker for Glucose Responsive Insulins

      Mannerstedt, K., Mishra, N. K., Engholm, E., Lundh, M., Madsen, C. S., Pedersen, P. J., Le‐huu, P., Pedersen, S. L., Buch‐månson, N., Borgström, B., Brimert, T., Fink, L. N., Fosgerau, K., Vrang, N. & Jensen, Knud Jørgen, 2021, In: Chemistry: A European Journal. 27, 9, p. 3166-3176 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      A plant chitinase controls cortical infection thread progression and nitrogen-fixing symbiosis

      Malolepszy, A., Kelly, S., Sørensen, K. K., James, E. K., Kalisch, C., Bozsoki, Z., Panting, M., Andersen, S. U., Sato, S., Tao, K., Jensen, D. B., Vinther, M., Jong, N. D., Madsen, L. H., Umehara, Y., Gysel, K., Berentsen, M. U., Blaise, M., Jensen, K. J., Thygesen, M. B. & 3 others, Sandal, N., Andersen, K. R. & Radutoiu, S., 2018, In: eLife. 7, p. 1-17 17 p., e38874.

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Automated 'X-Y' robot for peptide synthesis with microwave heating: application to difficult peptide sequences and protein domains

      Malik, L., Shelton, A. P. T., Pedersen, S. L., Sørensen, K. K. & Jensen, Knud Jørgen, 2010, In: Journal of Peptide Science. 16, 9, p. 506-512 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Perfluoroalkyl chains direct novel self-assembly of insulin

      Malik, L., Nygaard, J., Høiberg-Nielsen, R., Arleth, Lise, Høeg-Jensen, T. & Jensen, Knud Jørgen, 2012, In: Langmuir. 28, 1, p. 593-603 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

      Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      Self-assembly of designed coiled coil peptides studied by small-angle X-ray scattering and analytical ultracentrifugation

      Malik, L., Nygaard, J., Christensen, Niels Johan, Thulstrup, Peter Waaben, Arleth, Lise, Jensen, Knud Jørgen & Streicher, W., 2013, In: Journal of Peptide Science. 19, 5, p. 283-292 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Published

      De novo designed triple-helix bundle proteins on a carbohydrate template

      Malik, L., Nygaard, J., Høiberg-Nielsen, R., Christensen, Niels Johan, Thulstrup, Peter Waaben, Arleth, Lise & Jensen, Knud Jørgen, 2010, In: Journal of Peptide Science. S2

      Research output: Contribution to journal › Conference abstract in journal › Research

    98. Published

      Microwave-assisted solid-phase peptide synthesis using the biotage syro Wave™

      Malik, L. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 225-234 10 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    99. Published

      On-bead chemical synthesis and display of phosphopeptides for affinity pull-down proteomics

      Malene, B., Madsen, J. C., Bunkenborg, J., Jensen, O. N., Gammeltoft, S. & Jensen, Knud Jørgen, 2006, In: ChemBioChem. 7, 4, p. 623-630 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      Self‐Assembly of DNA–Peptide Supermolecules: Coiled‐Coil Peptide Structures Templated by d‐DNA and l-DNA Triplexes Exhibit Chirality‐Independent but Orientation‐Dependent Stabilizing Cooperativity

      Lou, C., Boesen, J. T., Christensen, Niels Johan, Sørensen, K. K., Thulstrup, Peter Waaben, Pedersen, M. N., Giralt, E., Jensen, Knud Jørgen & Wengel, J., 2020, In: Chemistry: A European Journal. 26, 25, p. 5676-5684 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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