Knud Jørgen Jensen
Professor
Department of Chemistry
Universitetsparken 5, 2100 København Ø, 71 Højhus 71, Building: 71-4-T425
Member of:
- Published
Synthesis and Characterization of Adamantane-Containing Heteropeptides with a Chirality Switch
Aloisi, A., Christensen, Niels Johan, Sorensen, K. K., Guilbaud-Chereau, C., Jensen, Knud Jørgen & Bianco, A., 2020, In: European Journal of Organic Chemistry. 2020, 7, p. 815-820Research output: Contribution to journal › Journal article › Research › peer-review
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Half-Life Extending Modifications of Peptide YY3-36 Direct Receptor-Mediated Internalization
Bech, E. M., Kaiser, A., Bellmann-Sickert, K., Nielsen, S. S., Sørensen, K. K., Elster, L., Hatzakis, Nikos, Pedersen, S. L., Beck-Sickinger, A. G. & Jensen, Knud Jørgen, 2019, In: Molecular Pharmaceutics. 16, 8, p. 3665-3677Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues
Bech, E. M., Martos-Maldonado, M. C., Wismann, P., Sorensen, K. K., van Witteloostuijn, S. B., Thygesen, Mikkel Boas, Vrang, N., Jelsing, J., Pedersen, S. L. & Jensen, Knud Jørgen, 2017, In: Journal of Medicinal Chemistry. 60, 17, p. 7434-7446 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical Strategies for Half-Life Extension of Biopharmaceuticals: Lipidation and Its Alternatives
Bech, E. M., Pedersen, S. L. & Jensen, Knud Jørgen, 12 Jul 2018, In: ACS Medicinal Chemistry Letters. 9, 7, p. 577-580 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved characterization of nod factors and genetically based variation in LysM receptor domains identify amino acids expendable for nod factor recognition in Lotus spp.
Bek, A. S., Sauer, J., Thygesen, Mikkel Boas, Duus, J. Ø., Petersen, B. O., Thirup, S. S., James, E., Jensen, Knud Jørgen, Stougaard, J. & Radutoiu, E. S., 2010, In: Molecular Plant - Microbe Interactions. 23, 1, p. 58-66 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regioselective fluorescent labeling of N,N,N-trimethyl chitosan via oxime formation
Benediktsdóttir, B. E., Sørensen, K. K., Thygesen, Mikkel Boas, Jensen, Knud Jørgen, Gudjónsson, T., Baldursson, Ó. & Másson, M., 2012, In: Carbohydrate Polymers. 90, 3, p. 1273-1280 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of N,N,N-trimethyl chitosan homopolymer and highly substituted N-alkyl-N,N-dimethyl chitosan derivatives with the aid of di-tert-butyldimethylsilyl chitosan
Benediktsdóttir, B. E., Gaware, V. S., Rúnarsson, Ö. V., Jónsdóttir, S., Jensen, Knud Jørgen & Másson, M., 2011, In: Carbohydrate Polymers. 86, 4, p. 1451–1460 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A high-throughput O-glycopeptide discovery platform for seromic profiling
Blixt, O., Cló, E., Nudelman, A. S., Sørensen, K. K., Clausen, T., Wandall, Hans H., Livingston, P. O., Clausen, Henrik & Jensen, Knud Jørgen, 2010, In: Journal of Proteome Research. 9, 10, p. 5250-5261 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New dendrimer - peptide host - guest complexes: towards dendrimers as peptide carriers
Boas, U., Söntjens, S. H. M., Jensen, Knud Jørgen, Christensen, J. B. & Meijer, E. W., 2002, In: ChemBioChem. 3, p. 433-439 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two dialkoxynaphthalene aldehydes as backbone amide linkers for solid-phase synthesis
Boas, U., Christensen, Jørn Bolstad & Jensen, Knud Jørgen, 2004, In: Journal of Combinatorial Chemistry. 6, 4, p. 497-503 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ¤ortho Backbone Amide Lnker (o-BAL) is an easily prepared and highly acid-labile handle for solid-phase synthesis
Boas, U., Brask, J., Christensen, J. B. & Jensen, Knud Jørgen, 2002, In: Journal of combinational chemistry. 4, p. 223-228 636 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Backbone amide linker in solid-phase synthesis
Boas, U., Brask, J. & Jensen, Knud Jørgen, 2009, In: Chemical Reviews. 109, 5, p. 2092-2118 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced hexamerization of insulin via assembly pathway rerouting revealed by single particle studies
Bohr, Freja Schmidt-Rasmussen, Bohr, S. S. R., Mishra, N. K., González-Foutel, N. S., Pinholt, H. D., Wu, S., Nielsen, E. M., Zhang, Min, Kjaergaard, M., Jensen, Knud Jørgen & Hatzakis, Nikos, 2023, In: Communications Biology . 6, 1, 14 p., 178.Research output: Contribution to journal › Journal article › Research › peer-review
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Softening of POPC membranes by magainin
Bouvrais, H., Méléard, P., Pott, T., Jensen, Knud Jørgen, Brask, J. & Ipsen, J. H., 2008, In: Biophysical Chemistry. 137, 1, p. 7-12 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ligand-recognizing motifs in plant LysM receptors are major determinants of specificity
Bozsoki, Z., Gysel, K., Hansen, S. B., Lironi, D., Krönauer, C., Feng, F., De Jong, N., Vinther, M., Kamble, M., Thygesen, M. B., Engholm, E., Kofoed, C., Fort, S., Sullivan, J. T., Ronson, C. W., Jensen, K. J., Blaise, M., Oldroyd, G., Stougaard, J., Andersen, K. R. & 1 others, , 7 Aug 2020, In: Science. 369, 6504, p. 663-670 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microwave heating for solid-phase peptide synthesis: general evaluation and application to 15-mer phosphopeptides
Brandt, M., Gammeltoft, S. & Jensen, Knud Jørgen, 2006, In: International Journal of Peptide Research and Therapeutics. 12, 4, p. 349-357 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Monolayers of a de novo designed 4-alfa-helix bundle carboprotein and partial structures on au(111).surfaces
Brask, J., Wackerbarth, H., Jensen, Knud Jørgen, Zhang, J., Nielsen, J. U., Andersen, J. E. T. & Ulstrup, J., 2002, In: Bioelectrochemistry. 56, p. 27-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Monolayer assemblies of a de novo designed 4-alpha-helix bndle carboprotein and its sulfur anchor fragment on Au(111) surfaces addressed by voltammetry and in situ scanning tunneling microscopy
Brask, J., Wackerbarth, H., Jensen, Knud Jørgen, Zhang, J., Chorkendorff, I. & Ulstrup, J., 2003, In: Journal of American Chemical Society. 125, p. 94-104 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fmoc solid-phase synthesis of peptide thioesters by masking as trithioortho esters
Brask, J., Albericio, F. & Jensen, Knud Jørgen, 2003, In: Organic Letters. 5, 16, p. 2951-2953 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Monosaccharide templates for de novo designed 4-alpha-helix bundle proteins: template effects in carboproteins
Brask, J., Dideriksen, J. M., Nielsen, J. & Jensen, Knud Jørgen, 2003, In: Organic and Biomolecular Chemistry. 1, 13, p. 2247-2252 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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tN-Ras, Synaptotagmin1 C2Ab, Annexinb12 and Amphiphysin NBAR can Discriminate Spherical from Cylindrical Membrane Curvature
kpl171, kpl171, Larsen, J., Rosholm, K. R., Pedersenb, S. L., Munch, H. K., Tkach, Vadym, Sakon, J. J., Bjornholm, T., Weninger, K. R., Bendix, Poul Martin, Jensen, Knud Jørgen, Uline, M. J., Hatzakis, Nikos & Stamou, Dimitrios, 2016, In: Biophysical Journal. 110, 3, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Legume receptors perceive the rhizobial lipochitin oligosaccharide signal molecules by direct binding
Broghammer, A., Krusell, L., Blaise, M., Sauer, J., Sullivan, J. T., Maolanon, N. N., Vinther, M., Lorentzen, A. M., Madsen, E. B., Jensen, Knud Jørgen, Roepstorff, P., Thirup, S. S., Ronson, C. W., Thygesen, Mikkel Boas & Stougaard, J., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 34, p. 13859-13864 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Computational Studies of the Stability and Chirality of Self-assembled Complexes of a Novel Iron(II)-binding Insulin Derivative
Christensen, Niels Johan, Munch, H. K., Heide, S. T., Høeg-Jensen, T., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2010, In: Journal of Peptide Science. S2Research output: Contribution to journal › Conference abstract in journal › Research
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Chemoselective reagents for covalent capture and display of glycans in microarrays
Cló, E., Blixt, K. O. & Jensen, Knud Jørgen, 2010, In: European Journal of Organic Chemistry. 2010, 3, p. 540-554 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the viral O-glycopeptidome: a novel tool of relevance for vaccine design and serodiagnosis
Cló, E., Kracun, S. K., Nudelman, A. S., Jensen, Knud Jørgen, Liljeqvist, J., Olofsson, S., Bergström, T. & Blixt, K. O., Jun 2012, In: Journal of Virology. 86, 11, p. 6268-78 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and evaluation of novel lipidated neuromedin U analogs with increased stability and effects on food intake
Dalbøge, L. S., Pedersen, S. L., van Witteloostuijn, S. B., Rasmussen, J. E., Rigbolt, K. T. G., Jensen, Knud Jørgen, Holst, B., Vrang, N. & Jelsing, J., 2015, In: Journal of Peptide Science. 21, 2, p. 85-94 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polyamine‐Functionalized 2′‐Amino‐LNA in Oligonucleotides: Facile Synthesis of New Monomers and High‐Affinity Binding towards ssDNA and dsDNA
Danielsen, M. B., Christensen, Niels Johan, Jørgensen, P. T., Jensen, Knud Jørgen, Wengel, J. & Lou, C., 2021, In: Chemistry: A European Journal. 27, 4, p. 1416-1422 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synergy of Two Highly Specific Biomolecular Recognition Events: Aligning an AT-Hook Peptide in DNA Minor Grooves via Covalent Conjugation to 2′-Amino-LNA
Ejlersen, M., Christensen, Niels Johan, Sørensen, K. K., Jensen, Knud Jørgen, Wengel, J. & Lou, C., 2018, In: Bioconjugate Chemistry. 29, p. 1025-1029 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression, receptor binding, and biophysical characterization of guinea pig insulin desB30: a monomeric insulin variant
Engholm, E., Hansen, Thomas Hesselhøj, Johansson, E., Strauss, H. M., Vinther, T. N., Jensen, Knud Jørgen, Hubálek, F. & Kjeldsen, T. B., 2015, In: ChemBioChem. 16, 6, p. 954-958 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metal-ion coordinated self-assembly of human insulin directs kinetics of insulin release as determined by preclinical SPECT/CT imaging
Engudar, G., Rodríguez-Rodríguez, C., Mishra, N. K., Bergamo, M., Amouroux, G., Jensen, Knud Jørgen, Saatchi, K. & Häfeli, U. O., 2022, In: Journal of Controlled Release. 343, p. 347-360Research output: Contribution to journal › Journal article › Research › peer-review
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Glucosamine derived DISAL donors for stereoselective glycosylations under neutral conditions
Grathe, S., Thygesen, Mikkel Boas, Larsen, K., Petersen, L. & Jensen, Knud Jørgen, 2005, In: Tetrahedron: Asymmetry. 16, 8, p. 1439-1448 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide-stabilized, fluorescent silver nanoclusters: solid-phase synthesis and screening
Gregersen, S., Vosch, Tom & Jensen, Knud Jørgen, 2016, In: Chemistry: A European Journal. 22, 51, p. 18492-18500 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immobilization of pectin fragments on solid supports: novel coupling by thiazolidine formation
Guillaumie, F., Thomas, O. R. T. & Jensen, Knud Jørgen, 2002, In: Bioconjugate Chemistry. 13, 2, p. 285-294 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Solid-supported enzymatic synthesis of pectic oligogalacturonides and their analysis by MALDI-TOF mass spectrometry
Guillaumie, F., Sterling, J. D., Jensen, Knud Jørgen, Thomas, O. R. T. & Mohnen, D., 2003, In: Carbohydrate Research. 338, 19, p. 1951-1960 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fractionation, solid-phase immobilization and chemical degradation of long pectin oligogalacturonides. Initial steps towards sequencin of oligosaccharides: initial steps towards sequencing of oligosaccharides
Guillaumie, F., Justesen, S. F. L., Mutenda, K. E., Roepstorff, P., Jensen, Knud Jørgen & Thomas, O. R. T., 2006, In: Carbohydrate Research. 341, 1, p. 118-129 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetic proofreading of lipochitooligosaccharides determines signal activation of symbiotic plant receptors
Gysel, K., Laursen, M., Thygesen, M. B., Lironi, D., Bozsóki, Z., Hjuler, C. T., Maolanon, N. N., Cheng, J., Bjørk, P. K., Vinther, M., Madsen, L. H., Rübsam, H., Muszyński, A., Ghodrati, A., Azadi, P., Sullivan, J. T., Ronson, C. W., Jensen, K. J., Blaise, M., Radutoiu, S. & 2 others, , 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 44, 10 p., e2111031118.Research output: Contribution to journal › Journal article › Research › peer-review
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Multivalent display of the antimicrobial peptides BP100 and BP143
Güell, I., Ferre, R., Sørensen, K. K., Badosa, E., Ng-Choi, I., Montesinos, E., Bardají, E., Feliu, L., Jensen, Knud Jørgen & Planas, M., 2012, In: Beilstein Journal of Organic Chemistry. 8, p. 2106-2117 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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X-ray crystal structure of a highly functionalized thiophene as a new backbone amide linker for solid-phase peptide synthesis: relationship between crystal structure and reactivity
Hammershøj, P., Jessing, M., Madsen, A. Ø., Jensen, Knud Jørgen, Christensen, J. B. & Boas, U., 2007, In: International Journal of Peptide Research and Therapeutics. 13, 1-2, p. 209-212 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Solid-phase synthesis of O-glycopeptides from N-dithiasuccinoyl-protected D-glucosamine derivatives
Hansen, Paul Robert, Jensen, Knud Jørgen & Barany, G., 1995, In: Peptides. 1994, p. 729-730 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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How membrane curvature drives the up-concentration of N-Ras proteins to ordered lipid domains: correlation of in vivo and in vitro experiments with mean field theory calculations and coarse grain simulations
Hatzakis, Nikos, Larsen, J. B., Jensen, M. B., Bhatia, V. K., Pedersen, S. L., Koldsoe, H., Fowler, P., Uline, M. J., Szleifer, I. G., Bjørnholm, T., Sansom, M., Jensen, Knud Jørgen & Stamou, Dimitrios, 2014, In: Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 713a 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Synergy of Liquid Ordered "Raft Like" Domains and Membrane Curvature in Promoting Sorting of Lipidated Proteins Such As NRas
Hatzakis, Nikos, Larsen, J. K., Jensen, M. B., Bhatia, V. K., Pedersen, S. L., Jensen, Knud Jørgen & Stamou, Dimitrios, 2012, In: Biophysical Journal. 102, 3 Supplement 1, p. 18a-19a 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Preparation of glycoconjugates from unprotected carbohydrates for protein-binding studies
Hjuler, C. T., Maolanon, N. N., Sauer, J., Stougaard, J., Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2017, In: Nature Protocols (Print). 12, 11, p. 2411-2422 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carbohydrate-Derived Metal-Chelator-Triggered Lipids for Liposomal Drug Delivery
Holmstrøm, T., Galsgaard Malle, M., Wu, S., Jensen, Knud Jørgen, Hatzakis, Nikos & Pedersen, Christian Marcus, 2021, In: Chemistry - A European Journal. 27, 23, p. 6917-6922 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors, using non-natural arginine analogues
Hosseini, M., Jiang, L., Sørensen, H. P., Jensen, J. K., Christensen, A., Fogh, S., Yuan, C., Andersen, L. M., Huang, M., Andreasen, P. & Jensen, Knud Jørgen, 2011, In: Molecular Pharmacology. 80, 4, p. 585-597 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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3- instead of 4-helix formation in a de novo designed protein in solution revealed by small-angle X-ray scattering
Høiberg-Nielsen, R., Shelton, A. P. T., Sørensen, K. K., Roessle, M., Svergun, D. I., Thulstrup, Peter Waaben, Jensen, Knud Jørgen & Arleth, Lise, 2008, In: ChemBioChem. 9, 16, p. 2663-2672 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Probing protein phosphatase substrate binding: affinity pull-down of ILKAP phosphatase 2C with phosphopeptides
Højlys-Larsen, K. B., Sørensen, K. K., Jensen, Knud Jørgen & Gammeltoft, S., 2012, In: Molecular BioSystems. 8, 5, p. 1452-1460 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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THAL, a sterically unhindered linker for the solid-phase synthesis of acid-sensitive protected peptide acids
Isidro-Llobet, A., Boas, U., Jensen, Knud Jørgen, Álvarez, M. & Albericio, F., 2008, In: Journal of Organic Chemistry. 73, 18, p. 7342-7344 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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End-to-end assembly of gold nanorods via oligopeptide linking and surfactant control: [and] Corrigendum to “End-to-end assembly of gold nanorods via oligopeptide linking and surfactant control”
Jain, T., Roodbeen, R., Reeler, N. E. A., Vosch, Tom, Jensen, Knud Jørgen, Bjørnholm, T. & Nørgaard, K., 2012, In: Journal of Colloid and Interface Science. 376, 1, p. 83-90 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Solid-phase glycopeptide synthesis of tyrosine-glycosylated glycogenin fragments as substrates for glucosylation by glycogenin
Jansson, A. M., Jensen, Knud Jørgen, Meldal, M., Lomako, J., Lomako, W. M., Olsen, C. E. & Bock, K., 1996, In: Journal of the Chemical Society - Perkin transactions 1. 1996, p. 1001-1006 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of 2-acetamido-2-deoxy- beta-D-glucopyranose O-glycopeptides from N-dithiasuccinoyl-protected derivatives
Jensen, Knud Jørgen, Hansen, Paul Robert, Venugopal, D. & Barany, G., 1996, In: Journal of the American Chemical Society. 118, 13, p. 3148-3155 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4238020
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Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization
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An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase
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A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility
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