Kenneth Lindegaard Madsen

Kenneth Lindegaard Madsen

Associate Professor


  1. 2020
  2. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, Gith, Jensen, Kathrine Louise, Rathje, Mette, Jensen, Dennis Bo, Erlendsson, Simon, Bartling, Christian Reinhard Otto, Ammendrup-Johnsen, I., Pedersen, Sofie E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, Kaare, Arleth, Lise, Sørensen, Andreas Toft, Bach, Anders, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Administration of a novel high affinity PICK1 PDZ domain inhibitor attenuates cocaine seeking in rats

    Turner, C., De Luca, M., Wolfheimer, J., Hernandez, N., Madsen, Kenneth Lindegaard & Schmidt, H. D., 2020, In: Neuropharmacology. 164, 107901.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Constitutive internalization across therapeutically targeted GPCRs correlates with constitutive activity

    Schmidt, Jan Hendrik, Perslev, Mathias, Bukowski, L., Stoklund, M., Herborg, Freja, Herlo, R. & Madsen, Kenneth Lindegaard, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, S6, p. 116-121 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2019
  6. Published

    Early Stage Alpha-Synuclein Amyloid Fibrils are Reservoirs of Membrane-Binding Species

    Skamris, T., Marasini, C., Madsen, Kenneth Lindegaard, Foderà, Vito & Vestergaard, Bente, 2019, In: Scientific Reports. 9, p. 1-11 11 p., 1733.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins

    Kasaragod, V. B., Hausrat, T. J., Schaefer, N., Kuhn, M., Christensen, N. R., Tessmer, I., Maric, H. M., Madsen, Kenneth Lindegaard, Sotriffer, C., Villmann, C., Kneussel, M. & Schindelin, H., 2019, In: Neuron. 101, 4, p. 673-689 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

    Erlendsson, Simon, Thorsen, Thor Seneca, Vauquelin, G., Ammendrup-Johnsen, I., Wirth, V., Martinez, Karen Laurence, Teilum, Kaare, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2019, In: eLife. 8, p. 1-27 e39180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Supported Cell Membrane Sheets to Monitor Protein Assembly

    Erlendsson, Simon, Thorsen, Thor Seneca & Madsen, Kenneth Lindegaard, 2019, In: Bio-protocol. 9, 18

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2018
  11. Published

    Drosophila Rab2 controls endosome-lysosome fusion and LAMP delivery to late endosomes

    Lund, Viktor Karlovich, Madsen, Kenneth Lindegaard & Kjærulff, Ole, 2018, In: Autophagy. 14, 9, p. 1520-1542 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    An Amphipathic Helix Directs Cellular Membrane Curvature Sensing and Function of the BAR Domain Protein PICK1

    Jensen, Rasmus Herlo Beenfeldt, Lund, Viktor Karlovich, Lycas, Matthew Domenic, Jansen, A. M., Khelashvili, G., Andersen, Rita Chan, Bhatia, V., Pedersen, T. S., Albornoz, P. B. C., Johner, N., Ammendrup-Johnsen, I., Christensen, N. R., Erlendsson, Simon, Stoklund, M., Larsen, J. B., Weinstein, H., Kjærulff, Ole, Stamou, Dimitrios, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2018, In: Cell Reports. 23, 7, p. 2056-2069 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis

    Jensen, Kathrine Louise, Sørensen, G., Dencker, D., Owens, W. A., Rahbek-Clemmensen, T., Brett Lever, M., Runegaard, A. H., Riis Christensen, N., Weikop, P., Wörtwein, Gitta, Fink-Jensen, Anders, Madsen, Kenneth Lindegaard, Daws, L., Gether, Ulrik & Rickhag, Karl Mattias, 2018, In: eNeuro. 5, 3

    Research output: Contribution to journalJournal articleResearchpeer-review

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