Kei Sakamoto

Kei Sakamoto

Professor

Member of:


    1. 2024
    2. Published

      The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions

      Lanfranchi, M., Yandiev, S., Meyer-Dilhet, G., Ellouze, S., Kerkhofs, M., Dos Reis, R., Garcia, A., Blondet, C., Amar, A., Kneppers, A., Polvèche, H., Plassard, D., Foretz, M., Viollet, B., Sakamoto, Kei, Mounier, R., Bourgeois, C. F., Raineteau, O., Goillot, E. & Courchet, J., 2024, In: Nature Communications. 15, 17 p., 2487.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b

      Uehara, K., Lee, W. D., Stefkovich, M., Biswas, Dipsikha, Santoleri, D., Whitlock, A. G., Quinn, W., Coopersmith, T., Creasy, K. T., Rader, D. J., Sakamoto, Kei, Rabinowitz, J. D. & Titchenell, P. M., 2024, In: Journal of Clinical Investigation. 134, 7, 13 p., e173782.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2023
    5. Published

      AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion

      Kneppers, A., Ben Larbi, S., Theret, M., Saugues, A., Dabadie, C., Gsaier, L., Ferry, A., Rhein, P., Gondin, J., Sakamoto, Kei & Mounier, R., 2023, In: iScience. 26, 12, 17 p., 108343.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Amino acid homeostasis is a target of metformin therapy

      Forteath, C., Mordi, I., Nisr, R., Gutierrez-Lara, E. J., Alqurashi, N., Phair, I. R., Cameron, A. R., Beall, C., Bahr, I., Mohan, M., Wong, A. K. F., Dihoum, A., Mohammad, A., Palmer, C. N. A., Lamont, D., Sakamoto, Kei, Viollet, B., Foretz, M., Lang, C. C. & Rena, G., 2023, In: Molecular Metabolism. 74, 16 p., 101750.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

      Negoita, F., Addinsall, A. B., Hellberg, K., Bringas, C. F., Hafen, P. S., Sermersheim, T. J., Agerholm, M., Lewis, C. T. A., Ahwazi, D., Ling, N. X. Y., Larsen, J. K., Deshmukh, A. S., Hossain, M. A., Oakhill, J. S., Ochala, J., Brault, J. J., Sankar, U., Drewry, D. H., Scott, J. W., Witczak, C. A. & 1 others, Sakamoto, Kei, 2023, In: Molecular Metabolism. 75, 14 p., 101761.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      In Vitro Screening for Probiotic Properties of Lactobacillus and Bifidobacterium Strains in Assays Relevant for Non-Alcoholic Fatty Liver Disease Prevention

      Lopez-Escalera, S., Lund, M. L., Hermes, G. D. A., Choi, Beatrice So-Yun, Sakamoto, Kei & Wellejus, A., 2023, In: Nutrients. 15, 10, 23 p., 2361.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. 2022
    10. Published

      Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis

      Neopane, K., Kozlov, N., Negoita, F., Murray-Segal, L., Brink, R., Hoque, A., Ovens, A. J., Tjin, G., McAloon, L. M., Yu, D., Ling, N. X. Y., Sanders, M. J., Oakhill, J. S., Scott, J. W., Steinberg, G. R., Loh, K., Kemp, B. E., Sakamoto, Kei & Galic, S., 2022, In: Cell Reports. 41, 12, 26 p., 111862.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function

      Cheung, R., Pizza, G., Chabosseau, P., Rolando, D., Tomas, A., Burgoyne, T., Wu, Z., Salowka, A., Thapa, A., Macklin, A., Cao, Y., Nguyen-Tu, M. S., Dickerson, M. T., Jacobson, D. A., Marchetti, P., Shapiro, J., Piemonti, L., de Koning, E., Leclerc, I., Bouzakri, K. & 4 others, Sakamoto, Kei, Smith, D. M., Rutter, G. A. & Martinez-Sanchez, A., 2022, In: Diabetes. 71, 7, p. 1525-1545 21 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Mechanism of glycogen synthase inactivation and interaction with glycogenin

      Marr, L., Biswas, Dipsikha, Daly, L. A., Browning, C., Vial, S. C. M., Maskell, D. P., Hudson, C., Bertrand, J. A., Pollard, J., Ranson, N. A., Khatter, H., Eyers, C. E., Sakamoto, Kei & Zeqiraj, E., 2022, In: Nature Communications. 13, 1, 14 p., 3372.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site

      Sanders, M. J., Ratinaud, Y., Neopane, K., Bonhoure, N., Day, E. A., Ciclet, O., Lassueur, S., Pinta, M. N., Deak, M., Brinon, B., Christen, S., Steinberg, G. R., Barron, D. & Sakamoto, Kei, 2022, In: Journal of Biological Chemistry. 298, 5, 15 p., 101852.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

      Nguyen-Tu, M., Harris, J., Martinez-Sanchez, A., Chabosseau, P., Hu, M., Georgiadou, E., Pollard, A., Otero, P., Lopez-Noriega, L., Leclerc, I., Sakamoto, Kei, Schmoll, D., Smith, D. M., Carling, D. & Rutter, G. A., 2022, In: Diabetologia. 65, p. 997-1011 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      PEN2: Metformin’s new partner at lysosome

      Sakamoto, Kei & Jessen, N., 2022, In: Cell Research. 32, p. 507-508

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids

      Desjardins, E. M., Smith, B. K., Day, E. A., Ducommun, S., Sanders, M. J., Nederveen, J. P., Ford, R. J., Pinkosky, S. L., Townsend, L. K., Gutgesell, R. M., Lu, R., Sakamoto, Kei & Steinberg, G. R., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 48, 8 p., e2119824119.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. 2021
    18. Published

      Skeletal muscle

      Markby, G. R. & Sakamoto, Kei, 1 Jan 2021, Autophagy in Health and Disease. Elsevier, p. 213-225 13 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    19. Published

      A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner

      Kopietz, F., Alshuweishi, Y., Bijland, S., Alghamdi, F., Degerman, E., Sakamoto, Kei, Salt, I. P. & Göransson, O., 2021, In: Biochemical Journal. 478, 3, p. 633-646 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

      Rhein, P., Desjardins, E. M., Rong, P., Ahwazi, D., Bonhoure, N., Stolte, J., Santos, M. D., Ovens, A. J., Ehrlich, A. M., Sanchez Garcia, J. L., Ouyang, Q., Yabut, J. M., Kjolby, M., Membrez, M., Jessen, N., Oakhill, J. S., Treebak, J. T., Maire, P., Scott, J. W., Sanders, M. J. & 4 others, Descombes, P., Chen, S., Steinberg, G. R. & Sakamoto, Kei, 2021, In: Molecular Metabolism. 51, 18 p., 101228.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

      Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. 2020
    23. Published

      AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

      Dohmen, M., Krieg, S., Agalaridis, G., Zhu, X., Shehata, S. N., Pfeiffenberger, E., Amelang, J., Bütepage, M., Buerova, E., Pfaff, C. M., Chanda, D., Geley, S., Preisinger, C., Sakamoto, Kei, Lüscher, B., Neumann, D. & Vervoorts, J., 2020, In: Nature Communications. 11, 1, 18 p., 1032.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Transcription factor EB and TFE3: new metabolic coordinators mediating adaptive responses to exercise in skeletal muscle?

      Markby, G. R. & Sakamoto, Kei, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 319, 4, p. E763-E768 6 p.

      Research output: Contribution to journalReviewResearchpeer-review

    25. 2019
    26. AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR

      Collodet, C., Foretz, M., Deak, M., Bultot, L., Metairon, S., Viollet, B., Lefebvre, G., Raymond, F., Parisi, A., Civiletto, G., Gut, P., Descombes, P. & Sakamoto, Kei, Nov 2019, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 11, p. 12374-12391 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Identification of novel PCTAIRE-1/CDK16 substrates using a chemical genetic screen

      Shehata, S. N., Deak, M., Collodet, C., Spiegl, S., Geley, S., Sumpton, D. & Sakamoto, Kei, Jul 2019, In: Cellular Signalling. 59, p. 53-61 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates

      Ducommun, S., Deak, M., Zeigerer, A., Göransson, O., Seitz, S., Collodet, C., Madsen, A. B., Jensen, Thomas Elbenhardt, Viollet, B., Foretz, M., Gut, P., Sumpton, D. & Sakamoto, Kei, 2019, In: Cellular Signalling. 57, p. 45-57 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. 2018
    30. AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

      Gélinas, R., Mailleux, F., Dontaine, J., Bultot, L., Demeulder, B., Ginion, A., Daskalopoulos, E. P., Esfahani, H., Dubois-Deruy, E., Lauzier, B., Gauthier, C., Olson, A. K., Bouchard, B., Des Rosiers, C., Viollet, B., Sakamoto, K., Balligand, J. L., Vanoverschelde, J. L., Beauloye, C., Horman, S. & 1 others, Bertrand, L., 1 Dec 2018, In: Nature Communications. 9, 1, 374.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. The Salt-Inducible Kinases: Emerging Metabolic Regulators

      Sakamoto, Kei, Bultot, L. & Göransson, O., Dec 2018, In: Trends in Endocrinology and Metabolism. 29, 12, p. 827-840 14 p.

      Research output: Contribution to journalReviewResearchpeer-review

    32. Ampk activation by a-769662 and 991 does not affect catecholamine-induced lipolysis in human adipocytes

      Kopietz, F., Berggreen, C., Larsson, S., Säll, J., Ekelund, M., Sakamoto, Kei, Degerman, E., Holm, C. & Göransson, O., Nov 2018, In: American Journal of Physiology - Endocrinology and Metabolism. 315, 5, p. E1075-E1085

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

      Hunter, R. W., Hughey, C. C., Lantier, L., Sundelin, E. I., Peggie, M., Zeqiraj, E., Sicheri, F., Jessen, N., Wasserman, D. H. & Sakamoto, Kei, 1 Sep 2018, In: Nature Medicine. 24, 9, p. 1395-1406 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

      Patra, K. C., Kato, Y., Mizukami, Y., Widholz, S., Boukhali, M., Revenco, I., Grossman, E. A., Ji, F., Sadreyev, R. I., Liss, A. S., Screaton, R. A., Sakamoto, Kei, Ryan, D. P., Mino-Kenudson, M., Castillo, C. F. D., Nomura, D. K., Haas, W. & Bardeesy, N., 1 Jul 2018, In: Nature Cell Biology. 20, 7, p. 811-822 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. MiR-184 expression is regulated by AMPK in pancreatic islets

      Martinez-Sanchez, A., Nguyen-Tu, M. S., Cebola, I., Yavari, A., Marchetti, P., Piemonti, L., De Koning, E., Shapiro, A. M. J., Johnson, P., Sakamoto, Kei, Smith, D. M., Leclerc, I., Ashrafian, H., Ferrer, J. & Rutter, G. A., May 2018, In: FASEB Journal. 32, 5, p. 2587-2600 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Metformin selectively targets redox control of complex I energy transduction

      Cameron, A. R., Logie, L., Patel, K., Erhardt, S., Bacon, S., Middleton, P., Harthill, J., Forteath, C., Coats, J. T., Kerr, C., Curry, H., Stewart, D., Sakamoto, Kei, Repiščák, P., Paterson, M. J., Hassinen, I., McDougall, G. & Rena, G., Apr 2018, In: Redox Biology. 14, p. 187-197 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stress

      Kfoury, A., Armaro, M., Collodet, C., Sordet-Dessimoz, J., Giner, M. P., Christen, S., Moco, S., Leleu, M., de Leval, L., Koch, U., Trumpp, A., Sakamoto, Kei, Beermann, F. & Radtke, F., 1 Mar 2018, In: EMBO Journal. 37, 5, e97673.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle

      Hingst, J. R., Bruhn, L., Hansen, M. B., Rosschou, M. F., Birk, Jesper Bratz, Fentz, J., Foretz, M., Viollet, B., Sakamoto, Kei, Færgeman, N. J., Havelund, J. F., Parker, B. L., James, D. E., Kiens, Bente, Richter, Erik A., Jensen, J. & Wojtaszewski, Jørgen F P, 2018, In: Molecular Metabolism. 16, p. 24-34 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. 2017
    40. The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

      Dite, T. A., Ling, N. X. Y., Scott, J. W., Hoque, A., Galic, S., Parker, B. L., Ngoei, K. R. W., Langendorf, C. G., O'Brien, M. T., Kundu, M., Viollet, B., Steinberg, G. R., Sakamoto, Kei, Kemp, B. E. & Oakhill, J. S., 1 Dec 2017, In: Nature Communications. 8, 1, 571.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. AMPKα1-LDH pathway regulates muscle stem cell self-renewal by controlling metabolic homeostasis

      Theret, M., Gsaier, L., Schaffer, B., Juban, G., Ben Larbi, S., Weiss-Gayet, M., Bultot, L., Collodet, C., Foretz, M., Desplanches, D., Sanz, P., Zang, Z., Yang, Lin, Vial, G., Viollet, B., Sakamoto, Kei, Brunet, A., Chazaud, B. & Mounier, R., 3 Jul 2017, In: EMBO Journal. 36, 13, p. 1946-1962 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

      Zibrova, D., Vandermoere, F., Göransson, O., Peggie, M., Mariño, K. V., Knierim, A., Spengler, K., Weigert, C., Viollet, B., Morrice, N. A., Sakamoto, Kei & Heller, R., 15 Mar 2017, In: Biochemical Journal. 474, 6, p. 983-1001 19 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16

      Dixon-Clarke, S. E., Shehata, S. N., Krojer, T., Sharpe, T. D., Von Delft, F., Sakamoto, Kei & Bullock, A. N., 1 Mar 2017, In: Biochemical Journal. 474, 5, p. 699-713 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Corrigendum: SIKs control osteocyte responses to parathyroid hormone

      Wein, M. N., Liang, Y., Goransson, O., Sundberg, T. B., Wang, J., Williams, E. A., O'Meara, M. J., Govea, N., Beqo, B., Nishimori, S., Nagano, K., Brooks, D. J., Martins, J. S., Corbin, B., Anselmo, A., Sadreyev, R., Wu, J. Y., Sakamoto, K., Foretz, M., Xavier, R. J. & 6 others, Baron, R., Bouxsein, M. L., Gardella, T. J., Divieti-Pajevic, P., Gray, N. S. & Kronenberg, H. M., 22 Feb 2017, In: Nature Communications. 8, 1 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. A Tbc1d1 Ser231Ala-knockin mutation partially impairs AICAR- but not exercise-induced muscle glucose uptake in mice

      Chen, Q., Xie, B., Zhu, S., Rong, P., Sheng, Y., Ducommun, S., Chen, L., Quan, C., Li, M., Sakamoto, Kei, MacKintosh, C., Chen, S. & Wang, H. Y., 2017, In: Diabetologia. 60, 2, p. 336-345 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. 2016
    47. Standardized LC×LC-ELSD Fractionation Procedure for the Identification of Minor Bioactives via the Enzymatic Screening of Natural Extracts

      Coulerie, P., Ratinaud, Y., Moco, S., Merminod, L., Naranjo Pinta, M., Boccard, J., Bultot, L., Deak, M., Sakamoto, Kei, Queiroz, E. F., Wolfender, J. L. & Barron, D., 23 Nov 2016, In: Journal of Natural Products. 79, 11, p. 2856-2864 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. SIKs control osteocyte responses to parathyroid hormone

      Wein, M. N., Liang, Y., Goransson, O., Sundberg, T. B., Wang, J., Williams, E. A., O'Meara, M. J., Govea, N., Beqo, B., Nishimori, S., Nagano, K., Brooks, D. J., Martins, J. S., Corbin, B., Anselmo, A., Sadreyev, R., Wu, J. Y., Sakamoto, K., Foretz, M., Xavier, R. J. & 6 others, Baron, R., Bouxsein, M. L., Gardella, T. J., Divieti-Pajevic, P., Gray, N. S. & Kronenberg, H. M., 19 Oct 2016, In: Nature Communications. 7, 13176.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle

      Sakakibara, I., Wurmser, M., Dos Santos, M., Santolini, M., Ducommun, S., Davaze, R., Guernec, A., Sakamoto, Kei & Maire, P., 5 Sep 2016, In: Skeletal Muscle. 6, 1, 30.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

      Cameron, A. R., Morrison, V. L., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, Kei, Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G., 19 Aug 2016, In: Circulation Research. 119, 5, p. 652-665 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

      Cameron, A. R., Logie, L., Patel, K., Bacon, S., Forteath, C., Harthill, J., Roberts, A., Sutherland, C., Stewart, D., Viollet, B., Sakamoto, Kei, McDougall, G., Foretz, M. & Rena, G., 1 Aug 2016, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 8, p. 1412-1422 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

      Mottillo, E. P., Desjardins, E. M., Crane, J. D., Smith, B. K., Green, A. E., Ducommun, S., Henriksen, T. I., Rebalka, I. A., Razi, A., Sakamoto, Kei, Schéele, Camilla Charlotte Nielsen, Kemp, B. E., Hawke, T. J., Ortega, J., Granneman, J. G. & Steinberg, G. R., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 118-129 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Medium-chain fatty acids inhibit mitochondrial metabolism in astrocytes promoting astrocyte-neuron lactate and ketone body shuttle systems

      Thevenet, J., De Marchi, U., Domingo, J. S., Christinat, N., Bultot, L., Lefebvre, G., Sakamoto, Kei, Descombes, P., Masoodi, M. & Wiederkehr, A., May 2016, In: FASEB Journal. 30, 5, p. 1913-1926 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding

      Langendorf, C. G., Ngoei, K. R. W., Scott, J. W., Ling, N. X. Y., Issa, S. M. A., Gorman, M. A., Parker, M. W., Sakamoto, Kei, Oakhill, J. S. & Kemp, B. E., 8 Mar 2016, In: Nature Communications. 7, 10912.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

      Bultot, L., Jensen, Thomas Elbenhardt, Lai, Y., Madsen, A. L. B., Collodet, C., Kviklyte, S., Deak, M., Yavari, A., Foretz, M., Ghaffari, S., Bellahcene, M., Ashrafian, H., Rider, M. H., Richter, Erik A. & Sakamoto, Kei, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 4, p. E706-E719 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion

      Chen, L., Chen, Q., Xie, B., Quan, C., Sheng, Y., Zhu, S., Rong, P., Zhou, S., Sakamoto, Kei, MacKintosh, C., Wang, H. Y. & Chen, S., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. 7219-7224 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. 2015
    58. Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16

      Shehata, S. N., Deak, M., Morrice, N. A., Ohta, E., Hunter, R. W., Kalscheuer, V. M. & Sakamoto, Kei, 1 Aug 2015, In: Biochemical Journal. 469, 3, p. 409-420 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate

      Ducommun, S., Deak, M., Sumpton, D., Ford, R. J., Núñez Galindo, A., Kussmann, M., Viollet, B., Steinberg, G. R., Foretz, M., Dayon, L., Morrice, N. A. & Sakamoto, Kei, 1 May 2015, In: Cellular Signalling. 27, 5, p. 978-988 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Expression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells

      Hunter, R. W., Zeqiraj, E., Morrice, N., Sicheri, F. & Sakamoto, Kei, Apr 2015, In: Protein Expression and Purification. 108, p. 23-29 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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