Kei Sakamoto

Kei Sakamoto

Professor

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    1. 2014

    2. The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

      Patel, K., Foretz, M., Marion, A., Campbell, D. G., Gourlay, R., Boudaba, N., Tournier, E., Titchenell, P., Peggie, M., Deak, M., Wan, M., Kaestner, K. H., Göransson, O., Viollet, B., Gray, N. S., Birnbaum, M. J., Sutherland, C. & Sakamoto, Kei, 4 Aug 2014, In: Nature Communications. 5, 4535.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Mechanism of action of compound-13: An α1-selective small molecule activator of AMPK

      Hunter, R. W., Foretz, M., Bultot, L., Fullerton, M. D., Deak, M., Ross, F. A., Hawley, S. A., Shpiro, N., Viollet, B., Barron, D., Kemp, B. E., Steinberg, G. R., Hardie, D. G. & Sakamoto, Kei, 17 Jul 2014, In: Chemistry and Biology. 21, 7, p. 866-879 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Structural basis for the recruitment of glycogen synthase by glycogenin

      Zeqiraj, E., Tang, X., Hunter, R. W., García-Rocha, M., Judd, A., Deak, M., Von Wilamowitz-Moellendorff, A., Kurinov, I., Guinovart, J. J., Tyers, M., Sakamoto, Kei & Sicheri, F., 15 Jul 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 28, p. E2831-E2840

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake

      Timmermans, A. D., Balteau, M., Gélinas, R., Renguet, E., Ginion, A., de Meester, C., Sakamoto, Kei, Balligand, J. L., Bontemps, F., Vanoverschelde, J. L., Horman, S., Beauloye, C. & Bertrand, L., 15 Jun 2014, In: American Journal of Physiology - Heart and Circulatory Physiology. 306, 12, p. H1619-H1630

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. The Ca2+/calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets

      Onselaer, M. B., Oury, C., Hunter, R. W., Eeckhoudt, S., Barile, N., Lecut, C., Morel, N., Viollet, B., Jacquet, L. M., Bertrand, L., Sakamoto, Kei, Vanoverschelde, J. L., Beauloye, C. & Horman, S., Jun 2014, In: Journal of Thrombosis and Haemostasis. 12, 6, p. 973-986 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662

      Ducommun, S., Ford, R. J., Bultot, L., Deak, M., Bertrand, L., Kemp, B. E., Steinberg, G. R. & Sakamoto, Kei, 15 Mar 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 6, p. E688-E696

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Mutation in the γ2-Subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage

      Kim, M., Hunter, R. W., Garcia-Menendez, L., Gong, G., Yang, Y. Y., Kolwicz, S. C., Xu, J., Sakamoto, Kei, Wang, W. & Tian, R., 14 Mar 2014, In: Circulation Research. 114, 6, p. 966-975 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Investigation of LKB1 Ser431 phosphorylation and Cys 433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity

      Houde, V. P., Ritorto, M. S., Gourlay, R., Varghese, J., Davies, P., Shpiro, N., Sakamoto, Kei & Alessi, D. R., 15 Jan 2014, In: Biochemical Journal. 458, 1, p. 41-56 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells

      De Meester, C., Timmermans, A. D., Balteau, M., Ginion, A., Roelants, V., Noppe, G., Porporato, P. E., Sonveaux, P., Viollet, B., Sakamoto, Kei, Feron, O., Horman, S., Vanoverschelde, J. L., Beauloye, C. & Bertrand, L., 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 20-29 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Salicylic acid: old and new implications for the treatment of type 2 diabetes?

      Rena, G. & Sakamoto, Kei, 1 Jan 2014, In: Diabetology International. 5, 4, p. 212-218 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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