Katrine Ter-Borch Gram Schjoldager
Associate Professor - Promotion Programme
Glycomics Program
Blegdamsvej 3, 2200 København N.
- 2023
- Published
Identification of global inhibitors of cellular glycosylation
Sørensen, D. M., Büll, C., Madsen, T. D., Lira-Navarrete, E., Clausen, T. M., Clark, A. E., Garretson, A. F., Karlsson, R., Pijnenborg, J. F. A., Yin, X., Miller, R. L., Chanda, S. K., Boltje, T. J., Schjoldager, K. T., Vakhrushev, S. Y., Halim, A., Esko, J. D., Carlin, A. F., Hurtado-Guerrero, R., Weigert, R. & 2 others, , 2023, In: Nature Communications. 14, 1, 19 p., 948.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase
Larsen, I. S. B., Povolo, Lorenzo, Zhou, L., Tian, W., Mygind, Kasper Johansen, Hintze, John, Jiang, C., Hartill, V., Prescott, K., Johnson, C. A., Mullegama, S. V., McConkie-Rosell, A., McDonald, M., Hansen, Lars, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Worzfeld, T., Joshi, Hiren Jitendra & Halim, Adnan, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 21, p. e2302584120Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Glycoproteomics
Bagdonaite, Ieva , Malaker, S. A., Polasky, D. A., Riley, N. M., Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Halim, Adnan, Aoki-Kinoshita, K. F., Nesvizhskii, A. I., Bertozzi, C. R., Wandall, Hans H., Parker, B. L., Thaysen-Andersen, M. & Scott, N. E., 2022, In: Nature Reviews Methods Primers. 2, 1, 29 p., 48.Research output: Contribution to journal › Review › Research › peer-review
- 2021
- Published
O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR
Tajadura-Ortega, V., Gambardella, G., Skinner, A., Halim, Adnan, Van Coillie, Julie, Schjoldager, Katrine Ter-Borch Gram, Beatson, R., Graham, R., Achkova, D., Taylor-Papadimitriou, J., Ciccarelli, F. D. & Burchell, J. M., 2021, In: Glycobiology. 31, 3, p. 200–210Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A Bump-and-Hole Approach to Dissect Regulation of Protein O-Glycosylation
Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik & Hurtado-Guerrero, R., 2020, In: Molecular Cell. 78, 5, p. 803-805 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Madsen, Thomas Daugbjerg, Hansen, L. H., Hintze, John, Ye, Z., Jebari, S., Andersen, Daniel Bjørklund, Joshi, Hiren Jitendra, Ju, T., Goetze, Jens P. , Martin, C., Rosenkilde, Mette, Holst, Jens Juul, Kuhre, Rune Ehrenreich, Goth, C. K., Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2020, In: Nature Communications. 11, 1, 13 p., 4033.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global view of human protein glycosylation pathways and functions
Schjoldager, Katrine Ter-Borch Gram, Narimatsu, Yoshiki, Joshi, Hiren Jitendra & Clausen, Henrik, 2020, In: Nature Reviews Molecular Cell Biology. 21, p. 729–749Research output: Contribution to journal › Review › Research › peer-review
- Published
Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function
Zilmer, M., Edmondson, A. C., Khetarpal, S. A., Alesi, V., Zaki, M. S., Rostasy, K., Madsen, C. G., Lepri, F. R., Sinibaldi, L., Cusmai, R., Novelli, A., Issa, M. Y., Fenger, C. D., Jamra, R. A., Reutter, H., Briuglia, S., Agolini, E., Hansen, L., Petäjä-Repo, U. E., Hintze, J. & 12 others, , 2020, In: Brain. 143, 4, p. 1114-1126 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding
Tian, E., Wang, S., Zhang, L., Zhang, Y., Malicdan, M. C., Mao, Y., Christoffersen, Christina, Tabak, L. A., Schjoldager, Katrine Ter-Borch Gram & Ten Hagen, K. G., 10 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25196-25202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation.
Steentoft, C., Yang, Zhang, Wang, S., Ju, T., Vester-Christensen, M. B., Festari, M. F., King-Smith, S. L., Moremen, K., Larsen, I. S. B., Goth, C. K., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Bennett, Eric Paul, Mandel, Ulla & Narimatsu, Yoshiki, 2019, In: Glycobiology. 29, 9, p. 645–656 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells
Narimatsu, Y., Joshi, H. J., Nason, R., Van Coillie, J., Karlsson, R., Sun, L., Ye, Z., Chen, Y-H., Schjoldager, K. T., Steentoft, C., Furukawa, S., Bensing, B. A., Sullam, P. M., Thompson, A. J., Paulson, J. C., Büll, C., Adema, G. J., Mandel, U., Hansen, L., Bennett, E. P. & 4 others, , 2019, In: Molecular Cell. 75, 2, p. 394-407, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Hansen, L. H., Madsen, Thomas Daugbjerg, Goth, C. K., Clausen, Henrik, Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, Jens Frederik, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram & Goetze, Jens P. , 2019, In: Journal of Biological Chemistry. 294, 34, p. 12567-12578 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics
Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Hintze, John, Halim, Adnan, Steentoft, C., Nason, R., Mandel, Ulla, Bennett, Eric Paul, Clausen, Henrik & Vakhrushev, Sergey, 2019, In: Molecular and Cellular Proteomics. 18, 7, p. 1396-1409Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
GlycoDomainViewer: A bioinformatics tool for contextual exploration of glycoproteomes
Joshi, Hiren Jitendra, Jørgensen, A., Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Dworkin, L. A., Steentoft, C., Wandall, Hans H., Clausen, Henrik & Vakhrushev, Sergey, 1 Mar 2018, In: Glycobiology. 28, 3, p. 131-136 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SnapShot: O-Glycosylation Pathways across Kingdoms
Joshi, Hiren Jitendra, Narimatsu, Yoshiki, Schjoldager, Katrine Ter-Borch Gram, Tytgat, H. L. P., Aebi, M., Clausen, Henrik & Halim, Adnan, Jan 2018, In: Cell. 172, 3, p. 632–632.e2Research output: Contribution to journal › Review › Research › peer-review
- Published
A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome
Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Zhang, Y., Gomes, C., Chen, Yen-Hsi, Lorenzetti, F., Furukawa, S., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Clausen, Henrik, Bennett, Eric Paul & Wandall, Hans H., 2018, In: Glycobiology. 28, 5, p. 295–305Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation
Goth, C. K., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Trends in Biochemical Sciences. 43, 4, p. 269-284 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases
Joshi, Hiren Jitendra, Hansen, Lars, Narimatsu, Yoshiki, Freeze, H. H., Henrissat, B., Bennett, Eric Paul, Wandall, Hans H., Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Glycobiology. 28, 5, p. 284-294Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines
Hintze, John, Ye, Z., Narimatsu, Yoshiki, Madsen, Thomas Daugbjerg, Joshi, Hiren Jitendra, Goth, C. K., Linstedt, A., Bachert, C., Mandel, Ulla, Bennett, Eric Paul, Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2018, In: The Journal of Biological Chemistry. 293, 49, p. 19064-19077 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions
Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T. & 1 others, , 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts
de Las Rivas, M., Coelho, H., Diniz, A., Lira-Navarrete, E., Compañón, I., Jiménez-Barbero, J., Schjoldager, Katrine Ter-Borch Gram, Bennett, Eric Paul, Vakhrushev, Sergey, Clausen, Henrik, Corzana, F., Marcelo, F. & Hurtado-Guerrero, R., 2018, In: Chemistry: A European Journal. 24, 33, p. 8382-8392Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation
King, S. L., Goth, C. K., Eckhard, U., Joshi, Hiren Jitendra, Haue, Amalie Dahl, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Overall, C. M. & Wandall, Hans H., 2018, In: The Journal of Biological Chemistry. 293, 20, p. 7629-7644 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Fine-tuning limited proteolysis - A novel role for regulated site-specific O-glycosylation in beta 1-Adrenergic Receptor cleavage and function
Goth, C. K., Tuhkanen, H. E., Khan, H., Wang, S., Narimatsu, Yoshiki, Hansen, L. H., Overall, C., Clausen, Henrik, Schjoldager, Katrine Ter-Borch Gram & Petaja-Repo, U., Dec 2017, In: Glycobiology. 27, 12, p. 1204-1204 84.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Mapping sites and molecular functions of O-glycosylation
Schjoldager, Katrine Ter-Borch Gram, Wang, S., Joshi, Hiren Jitendra, Mao, Y. & Vakhrushev, Sergey, Dec 2017, In: Glycobiology. 27, 12, p. 1189-1189 47.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Chromogranin A in the mammalian heart: Expression without secretion
Hansen, L. H., Darkner, S., Svendsen, Jesper Hastrup, Henningsen, K., Pehrson, S., Chen, X., Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram & Goetze, Jens P. , Jul 2017, In: Biomarkers in Medicine. 11, 7, p. 541-545 5 p.Research output: Contribution to journal › Letter › Research › peer-review
ID: 920646
Most downloads
-
105
downloads
Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Research output: Contribution to journal › Review › Research › peer-review
Published -
98
downloads
An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
33
downloads
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase
Research output: Contribution to journal › Journal article › Research › peer-review
Published