Kasper Skytte Harpsøe
Peptides and Proteins
Jagtvej 162, 2100 København Ø
09/2019 - : Academic Staff, Department of Drug Design and Pharmacology, Faculty of Health and Medical Scineces
2006: Ph.D., The Danish University of Pharmaceutical Sciences
Title: Computational Studies on Allosteric Modulations of Ionotropic Glutamate Receptors
2001: Master of Science in pharmacy (Cand. Pharm.), The Royal Danish School of Pharmacy
Masters thesis title: Evaluation of MultiSelect and MultiScore - An Evaluation of New Procedures for Predicting Binding Conformation and Binding Affinity
01/2014 - 08/2015 : Post doc, Department of Drug Design and Pharmacology, Faculty of Health and Medical Scineces
03/2012 - 12/2013: Post doc, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Scineces
11/2011 – 02/2012: Postdoc, Faculty of Pharmaceutical Sciences, University of Copenhagen
12/2007 - 06/2011: Postdoc, Faculty of Pharmaceutical Sciences, University of Copenhagen
07/2007 – 11/2007: Scientific Assistant, Faculty of Pharmaceutical Sciences, University of Copenhagen
07/2006 – 06/2007: Research Scientist (Post Doc.), Arpida A/S, Department of Structural Chemistry
05/2006 – 06/2006: Scientific Assistant, The Danish University of Pharmaceutical Sciences
05/2003 – 04/2006: Ph.D. Student, The Danish University of Pharmaceutical Sciences (including three months traineeship at Schrödinger Inc. New York)
02/2002 – 04/2003: Clinical Research Associate, Quintiles AB
11/2001 – 01/2002: Pharmacist (temporary position), The Danish Medicines Agency, Department of Clinical Trials.
- Binding site identification and characterization
- Docking and binding pose evaluation
- Protein-ligand interactions
- Conformational analysis
- Structure-based ligand design
- Sequence analysis
- Homology modeling
- Molecular dynamics
- Prediction of protein-ligand binding energy
- Quantum Chemistry calculations
2005 - Three month as trainee at Schrödinger.
Performed a validation project on Liaison and gained general experience with the Schrödinger molecular modeling software suite; especially with the extra options and setting available through the command line utilities.
2008 - Two weeks stay with the Carlson research group at University of Michigan.
Gained hands-on experience with setting up Molecular dynamics calculations of large protein-ligand complexes.
Ph.D. and M.Sc. Pharm.