Karla Andrea Frydenvang

Karla Andrea Frydenvang

Associate Professor

ORCID: 0000-0002-5823-3478

Introductory remarks on publicationslist

See Homepage for complete list of publications (incl. all publications from before 2007)
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  1. Published

    På jagt efter et virkningssted i hjernen

    Frydenvang, Karla Andrea, Juknaite, L. & Kastrup, Jette Sandholm Jensen, 2013, In: Lægemiddelforskning. p. 50-52 3 p.

    Research output: Contribution to journal › Journal article › Communication

  2. Published

    Rational design, synthesis, and pharmacological evaluation of 2-azanorbornane-3-exo,5-endo-dicarboxylic acid: a novel conformationally restricted glutamic acid analogue

    Bunch, Lennart, Liljefors, T., Greenwood, J. R., Frydenvang, Karla Andrea, Bräuner, Hans, Krogsgaard-Larsen, Povl & Madsen, Ulf, 2003, In: Journal of Organic Chemistry. 68, 4, p. 1489-95 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA

    Johansen, Tommy Nørskov, Stensbøl, T. B., Nielsen, Birgitte, Vogensen, S. B., Frydenvang, Karla Andrea, Sløk, F. A., Bräuner, Hans, Madsen, Ulf & Krogsgaard-Larsen, Povl, 2001, In: Chirality. 13, 9, p. 523-32 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H- tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist

    Vogensen, S. B., Jensen, H. S., Stensbøl, T. B., Frydenvang, Karla Andrea, Bang-Andersen, B., Johansen, Tommy Nørskov, Egebjerg, J. & Krogsgaard-Larsen, Povl, 2000, In: Chirality. 12, 10, p. 705-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Selective Inhibitors of Glial GABA Uptake: Synthesis, Absolute Stereochemistry, and Pharmacology of the Enantiomers of 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and Analogues

    Falch, E., Frølund, Bente, Perregaard, Sanchez, C., Søkilde, B., Buur, A., Hansen, A., Frydenvang, Karla Andrea, Brehm, L., Bolvig, T., Larsson, O. M., Schousboe, Arne & Krogsgaard-Larsen, Povl, 1999, In: Journal of Medicinal Chemistry. 42, p. 5402–5414

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Selective kainate receptor (GluK1) ligands structurally based upon1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization

    Venskutonyte, R., Butini, S., Coccone, S. S., Gemma, S., Brindisi, M., Kumar, V., Guarino, E., Maramai, S., Valenti, S., Amir, A., Valades, E. A., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen, Novellino, E., Campiani, G. & Pickering, Darryl S, 14 Jul 2011, In: Journal of Medicinal Chemistry. 54, 13, p. 4793-4805

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida

    Rubal, J. J., Guerra, F. M., Moreno-Dorado, F. J., Jorge, Z. D., Massanet, G. M., Søhoel, H., Smitt, U. W., Frydenvang, Karla Andrea, Christensen, Søren Brøgger, Nielsen, C. & Eriksson, M., 2006, In: Journal of Natural Products. 69, 11, p. 1566-71 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure

    Bay, Yasmin, Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, Karla Andrea, Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, Anders Skov, Boesen, T., Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2024, In: FEBS Journal. 291, 7, p. 1506-1529

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In: Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Some transformations of tacrolimus, an immunosuppressive drug

    Skytte, D. M., Jaroszewski, J. W., Kongstad, Kenneth Thermann, Hansen, S. H., Hansen, L., G. Nielsen, P. & Frydenvang, Karla Andrea, 2013, In: European Journal of Pharmaceutical Sciences. 48, 3, p. 514-522 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist

    Stensbøl, T. B., Jensen, H. S., Nielsen, Birgitte, Johansen, Tommy Nørskov, Egebjerg, J., Frydenvang, Karla Andrea & Krogsgaard-Larsen, Povl, 2001, In: European Journal of Pharmacology. 411, 3, p. 245-53 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Stereospecific GABA-B receptor antagonism

    Frydenvang, Karla Andrea, Frølund, Bente, Kristiansen, Uffe & Krogsgaard-Larsen, Povl, 1996, GABA, receptors, transporters and metabolism. Tanaka, C. & Bowery, N. G. (eds.). Basel: Birkhäuser Verlag

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  13. Published

    Stereostructure-activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors

    Johansen, Tommy Nørskov, Greenwood, J. R., Frydenvang, Karla Andrea, Madsen, Ulf & Krogsgaard-Larsen, Povl, 2003, In: Chirality. 15, 2, p. 167-79 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol

    Frydenvang, Karla Andrea, Verkade-Vreeker, M. C. A., Dohmen, F., Commandeur, J. N. M., Rafiq, M., Mirza, Osman Asghar, Jørgensen, Flemming Steen & Geerke, D. P., 2019, In: PLoS ONE. 14, 5, 15 p., e0217292.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain

    Krintel, C., Harpsøe, Kasper, Zachariassen, L. G., Peters, D., Frydenvang, Karla Andrea, Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2013, In: Acta Crystallographica Section D: Structural Biology. 69, Pt 9, p. 1645-1652 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors

    Venskutonyte, R., Frydenvang, Karla Andrea, Valadés, E. A., Szymanska, E. M., Johansen, Tommy Nørskov, Kastrup, Jette Sandholm Jensen & Pickering, Darryl S, Oct 2012, In: ChemMedChem. 7, 10, p. 1793-1798 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Structural basis for positive allosteric modulation of AMPA and kainate receptors

    Frydenvang, Karla Andrea, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2022, In: The Journal of Physiology. 600, 2, p. 181-200

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Structural characterisation and dehydration behaviour of siramesine hydrochloride

    Zimmermann, A., Tian, F., Lopez de Diego, H., Frydenvang, Karla Andrea, Rantanen, Jukka, Elema, M. R. & Hovgaard, L., 2009, In: Journal of Pharmaceutical Sciences. 98, 10, p. 3596-3607

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Structural characteristics of isoxazol-3-ol and isothiazol-3-ol, carboxy group bioisosteres examined by X-ray crystallography and ab initio calculations

    Frydenvang, Karla Andrea, Matzen, L., Norrby, P. O., Sløk, F. A., Liljefors, T., Krogsgaard-Larsen, Povl & Jaroszewski, J. W., Sep 1997, In: Journal of the Chemical Society. Perkin Transactions 2. 9, p. 1783-1791 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Structural features of ATPA and thio-ATPA - Potent and selective gluR5 receptor agonists. Crystal structure determinations and quantum chemical calculations

    Frydenvang, Karla Andrea, Greenwood, J. R., Vogensen, S. B. & Brehm, L., Dec 2002, In: Structural Chemistry. 13, 5-6, p. 479-490 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors

    Møllerud, S., Pinto, A., Marconi, L., Frydenvang, Karla Andrea, Thorsen, T. S., Laulumaa, S. K., Venskutonyte, R., Winther, Nikolaj Sebastian, Cunado Moral, A. M., Tamborini, L., Conti, P., Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2017, In: A C S Chemical Neuroscience. 8, 9, p. 2056-2064 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Structure determinations of (dl)‐trans‐3‐hydroxy‐5‐iodomethyl‐2,2‐diphenyltetrahydrofuran and (dl)‐trans‐N,N,N‐trimethyl‐(3‐hydroxy‐2,2‐diphenyltetrahydro‐5‐furyl)methylammonium iodide

    Frydenvang, Karla Andrea, Oct 1993, In: Acta Crystallographica Section C. 49, 10, p. 1837-1840 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Structure elucidation of prenyl- and geranyl substituted coumarins in Gerbera piloselloides by NMR spectroscopy, electronic circular dichroism calculations, and single crystal X-ray crystallography

    Li, T., Ma, X., Fedotov, D., Kjaerulff, Louise, Frydenvang, Karla Andrea, Coriani, S., Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 8 Apr 2020, In: Molecules. 25, 25 p., 1706.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Structure of (–)‐muscarone iodide

    Frydenvang, Karla Andrea, Oct 1993, In: Acta Crystallographica Section C. 49, 10, p. 1834-1837 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Structure of Muscarine Chloride

    Frydenvang, Karla Andrea & Jensen, B., 1990, In: Acta Crystallographica Section C: Crystal Structure Communications. C46, 7, p. 1279-1282

    Research output: Contribution to journal › Journal article › Research › peer-review

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