Karel Miettinen

Karel Miettinen

Assistant Professor

Member of:

    ORCID: 0000-0003-2496-8924

    Publication year:
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    1 - 10 out of 17Page size: 10
    1. 2024
    2. Published

      Celastrol: A century-long journey from the isolation to the biotechnological production and the development of an antiobesity drug

      Zhao, Yong, Miettinen, Karel & Kampranis, Sotirios, 2024, In: Current Opinion in Plant Biology. 81, 8 p., 102615.

      Research output: Contribution to journal › Review › Research › peer-review

    3. 2023
    4. Published

      Biosynthesis and biotechnological production of the anti-obesity agent celastrol

      Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. 2022
    6. Published

      A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

      Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks

      Ignea, C., Raadam, Morten Hessellund, Koutsaviti, A., Zhao, Yong, Duan, Yaotao, Harizani, M., Miettinen, Karel, Georgantea, P., Rosenfeldt, M., Viejo-Ledesma, S. E., Petersen, Mikael Agerlin, Bredie, Wender, Stærk, Dan, Roussis, V., Ioannou, E. & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 5188.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. 2020
    9. Published

      Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol

      Hansen, N. L., Miettinen, Karel, Zhao, Yong, Ignea, C., Andreadeli, A., Raadam, Morten Hessellund, Makris, A. M., Møller, Birger Lindberg, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2020, In: Microbial Cell Factories. 19, 17 p., 15.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. 2019

    11. Integrated metabolomics identifies CYP72A67 and CYP72A68 oxidases in the biosynthesis of Medicago truncatula oleanate sapogenins

      Tzin, V., Snyder, J. H., Yang, D. S., Huhman, D. V., Watson, B. S., Allen, S. N., Tang, Y., Miettinen, Karel, Arendt, P., Pollier, J., Goossens, A. & Sumner, L. W., 2019, In: Metabolomics. 15, 6, 85.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. 2018

    13. Metabolic alteration of Catharanthus roseus cell suspension cultures overexpressing geraniol synthase in the plastids or cytosol

      Saiman, M. Z., Miettinen, Karel, Mustafa, N. R., Choi, Y. H., Verpoorte, R. & Schulte, A. E., 2018, In: Plant Cell, Tissue and Organ Culture. 134, 1, p. 41-53 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      The TriForC database: a comprehensive up-to-date resource of plant triterpene biosynthesis

      Miettinen, Karel, Inigo, S., Kreft, L., Pollier, J., De Bo, C., Botzki, A., Coppens, F., Bak, Søren & Goossens, A., 2018, In: Nucleic Acids Research. 46, D1, p. D586-D594 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. 2017

    16. A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules

      Reed, J., Stephenson, M. J., Miettinen, Karel, Brouwer, B., Leveau, A., Brett, P., Goss, R. J. M., Goossens, A., O'Connell, M. A. & Osbourn, A., 2017, In: Metabolic Engineering. 42, p. 185-193 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. An endoplasmic reticulum-engineered yeast platform for overproduction of triterpenoids

      Arendt, P., Miettinen, Karel, Pollier, J., De Rycke, R., Callewaert, N. & Goossens, A., 2017, In: Metabolic Engineering. 40, p. 165-175 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 194204863