Johanne Marie Justesen
Assistant Professor
Grarup Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal, 2200 København N.
- 2023
- Published
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide
Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S. K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J. E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M. T. & 83 others, , 2023, In: Nature Communications. 14, 18 p., 5843.Research output: Contribution to journal › Journal article › peer-review
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant
Guo, H., Yu, X., Liu, Y., Paik, D. T., Justesen, J. M., Chandy, M., Jahng, J. W. S., Zhang, T., Wu, W., Rwere, F., Zhao, S. R., Pokhrel, S., Shivnaraine, R. V., Mukherjee, S., Simon, D. J., Manhas, A., Zhang, A., Chen, C. H., Rivas, M. A., Gross, E. R. & 2 others, , 2023, In: Science Translational Medicine. 15, 680, eabp9952.Research output: Contribution to journal › Journal article › peer-review
- 2022
- Published
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
Wei, T-T., Chandy, M., Nishiga, M., Zhang, A., Kumar, K. K., Thomas, D., Manhas, A., Rhee, S., Justesen, J. M., Chen, I. Y., Wo, H-T., Khanamiri, S., Yang, J. Y., Seidl, F. J., Burns, N. Z., Liu, C., Sayed, N., Shie, J-J., Yeh, C-F., Yang, K-C. & 5 others, , 2022, In: Cell. 185, 10, p. 1676-1693.e23Research output: Contribution to journal › Journal article › peer-review
Integration of rare expression outlier-associated variants improves polygenic risk prediction
Smail, C., Ferraro, N. M., Hui, Q., Durrant, M. G., Aguirre, M., Tanigawa, Y., Keever-Keigher, M. R., Rao, A. S., Justesen, Johanne Marie, Li, X., Gloudemans, M. J., Assimes, T. L., Kooperberg, C., Reiner, A. P., Huang, J., O'Donnell, C. J., Sun, Y. V., Rivas, M. A., Montgomery, S. B. & Million Veteran Program, M. V. P., 2022, In: American Journal of Human Genetics. 109, 6, p. 1055-1064Research output: Contribution to journal › Journal article › peer-review
- Published
Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD
Schnurr, T. M., Katz, S. F., Justesen, Johanne Marie, O'Sullivan, J. W., Saliba-Gustafsson, P., Assimes, T. L., Carcamo-Orive, I., Ahmed, A., Ashley, E. A., Hansen, Torben & Knowles, J. W., 2022, In: Hepatology Communications. 6, 7, p. 1516-1526Research output: Contribution to journal › Journal article › peer-review
Significant sparse polygenic risk scores across 813 traits in UK Biobank
Tanigawa, Y., Qian, J., Venkataraman, G., Justesen, Johanne Marie, Li, R., Tibshirani, R., Hastie, T. & Rivas, M. A., 2022, In: PLOS Genetics. 18, 3, 21 p., e1010105.Research output: Contribution to journal › Journal article › peer-review
- 2021
Survival Analysis on Rare Events Using Group-Regularized Multi-Response Cox Regression
Li, R., Tanigawa, Y., Justesen, Johanne Marie, Taylor, J., Hastie, T., Tibshirani, R. & Rivas, M. A., 9 Feb 2021, In: Bioinformatics.Research output: Contribution to journal › Journal article › peer-review
- Published
Combinatorial, additive and dose-dependent drug–microbiome associations
Forslund, S. K., Chakaroun, R., Zimmermann-Kogadeeva, M., Markó, L., Aron-Wisnewsky, J., Nielsen, T., Moitinho-Silva, L., Schmidt, T. S. B., Falony, G., Vieira-Silva, S., Adriouch, S., Alves, R. J., Assmann, K., Bastard, J. P., Birkner, T., Caesar, R., Chilloux, J., Coelho, L. P., Fezeu, L., Galleron, N. & 23 others, , 2021, In: Nature. 600, p. 500-517 18 p.Research output: Contribution to journal › Journal article › peer-review
Combining Clinical and Polygenic Risk Improves Stroke Prediction among Individuals with Atrial Fibrillation
O'Sullivan, J. W., Shcherbina, A., Justesen, Johanne Marie, Turakhia, M., Perez, M., Wand, H., Tcheandjieu, C., Clarke, S. L., Rivas, M. A. & Ashley, E. A., 2021, In: Circulation: Genomic and Precision Medicine. 14, 3, p. 339-347 9 p., e003168.Research output: Contribution to journal › Journal article › peer-review
- 2020
Fast Lasso method for large-scale and ultrahigh-dimensional Cox model with applications to UK Biobank
Li, R., Chang, C., Justesen, Johanne Marie, Tanigawa, Y., Qiang, J., Hastie, T., Rivas, M. A. & Tibshirani, R., 2020, In: Biostatistics.Research output: Contribution to journal › Journal article › peer-review
Pervasive additive and non-additive effects within the HLA region contribute to disease risk in the UK Biobank
Venkataraman, G. R., Olivieri, J. E., DeBoever, C., Tanigawa, Y., Justesen, Johanne Marie, Dilthey, A. & Rivas, M. A., 2020, bioRxiv, 19 p.Research output: Working paper › Preprint › Research
- 2019
- Published
PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training
Blond, Martin Bæk, Schnurr, T. M., Rasenkilde, M., Quist, Jonas Salling, Gram, A. S., Reichkendler, M. H., Auerbach, P. L., Nordby, P., Skovgaard, Lene Theil, Ribel-Madsen, R., Justesen, Johanne Marie, Kilpeläinen, Tuomas O., Ploug, Thorkil, Stallknecht, Bente Merete & Hansen, Torben, 2019, In: Physiological Genomics. 51, 6, p. 254-260Research output: Contribution to journal › Journal article › peer-review
- Published
Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology
Tanigawa, Y., Li, J., Justesen, Johanne Marie, Horn, H., Aguirre, M., DeBoever, C., Chang, C., Narasimhan, B., Lage, K., Hastie, T., Park, C. Y., Bejerano, G., Ingelsson, E. & Rivas, M. A., 2019, In: Nature Communications. 10, 14 p., 4064.Research output: Contribution to journal › Journal article › peer-review
- Published
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A. & 31 others, , 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.Research output: Contribution to journal › Journal article › peer-review
- 2018
- Published
Interethnic analyses of blood pressure loci in populations of East Asian and European descent
The International Genomics of Blood Pressure (iGEN-BP) Consortium, T. I. G. O. B. P. (. C., 2018, In: Nature Communications. 9, 5052.Research output: Contribution to journal › Journal article › peer-review
- Published
Meta-analysis of exome array data identifies six novel genetic loci for lung function
Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., Manichaikul, A., Pottinger, T. D. & 31 others, , 2018, In: Wellcome Open Research. 3, p. 1-28Research output: Contribution to journal › Journal article › peer-review
- 2017
- Published
Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, , 19 Dec 2017, In: Scientific Data. 4, p. 1-20 20 p., 170179.Research output: Contribution to journal › Journal article › peer-review
- Published
Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › peer-review
- Published
A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, , Dec 2017, In: Diabetes. 66, p. 2019-2032 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, , 26 Apr 2017, In: Nature Communications. 8, 19 p., 14977.Research output: Contribution to journal › Journal article › peer-review
- Published
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 34 others, , 1 Apr 2017, In: PLOS Genetics. 13, 4, e1006528.Research output: Contribution to journal › Journal article › peer-review
- 2016
- Published
Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years
Justesen, Johanne Marie, Andersson, E. A., Allin, K. H., Sandholt, C. H., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye & Grarup, Niels, Dec 2016, In: Journal of Lipid Research. 57, 12, p. 2193-2199 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried, J. S., Jeff M, J., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. V. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, , 23 Nov 2016, In: Nature Communications. 7, 11 p., 13357.Research output: Contribution to journal › Journal article › peer-review
- Published
The genetic architecture of type 2 diabetes
Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, , 4 Aug 2016, In: Nature. 536, 7614, p. 41-47 7 p.Research output: Contribution to journal › Journal article › peer-review
- 2015
- Published
A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals
Krarup, N. T., Borglykke, A., Allin, K. H., Sandholt, C. H., Justesen, Johanne Marie, Andersson, E. A., Grarup, Niels, Jørgensen, T., Pedersen, O. & Hansen, T., Jun 2015, In: Atherosclerosis. 240, 2, p. 305-10 6 p.Research output: Contribution to journal › Journal article › peer-review
ID: 32361721
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Research output: Contribution to journal › Journal article › peer-review
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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Research output: Contribution to journal › Journal article › peer-review
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175
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A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Research output: Contribution to journal › Journal article › peer-review
Published