Jette Sandholm Jensen Kastrup

• Presentation
• CV
• Research outputs
• Activities

February 2022

Brief Research CV: Jette Sandholm Kastrup                                                                                    

Work address: Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 152, DK-2100 CPH Ø, Denmark

Phone: +45 3533 6486; E-mail: jsk@sund.ku.dk

Academic Degrees

1980: Studentereksamen (General Certificate of Education A-level) from Holstebro Gymnasium

1986: M.Sc. (pharm.), The Royal Danish School of Pharmacy (RDSP). June 3

1988: PhD (Industrial PhD, Erhvervsforsker). September 23. Cheminova A/S and RDSP

Current and previous positions

1981-1982: 11 Months work experience at Tårnby Apotek

1982-1986: Periodic substitute at Tårnby Apotek

1986-1988: Industrial PhD student (Erhvervsforsker). RDSP & Cheminova Agro

1988: Teaching assistant. Dept. of Organic Chemistry, RDSP (3 months)

1989-1992: Post doc. Dept. of Medicinal Chemistry, RDSP

• stay as visiting research fellow at Novo Nordisk A/S, dr. Hans Flodgaard. Protein purification (in total 2 months in 1989-1991)
• stay as visiting research fellow at University of Oregon, USA, Professor Brian W. Matthews. Protein crystallography (1 month in 1990 and 2 weeks in 1991)
• stay as visiting research fellow at Uppsala University, Sweden, Dr. Elisabeth S. Eriksson. Protein crystallography (1 week in 1991)
• stay as visiting research fellow at DAKO A/S, Dr. Inge Clemmensen. Protein purification (3 months in 1992)

1993-1994: Senior scientist. Dept. of Medicinal Chemistry, RDSP

1995-2008: Associate professor. Dept. of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences (DUPS)

2008-2016: Professor (MSO) in structure-based drug design. Dept. of Drug Design and Pharmacology (ILF), The Faculty of Health and Medical Sciences, University of Copenhagen

2016-present: Professor in experimental structure-based drug design. ILF, KU

2019-present: Deputy head of ILF, KU with focus on research

Research prizes

45.000 kr. from ”Valborg and Edith Larsens Foundation" 2005

20.000 kr from the Faculty of Pharmaceuitcal Sciences, University of Copenhagen 2007                                                    

Major Responsibilities

1999-2002: Member of Board, the Dansync Center for synchrotron radiation

2002-2008: Member of departmental board, Dept. of Medicinal Chemistry, DUPS

2004-2008: Deputy Head of Dept. of Medicinal Chemistry. DUPS and the Faculty of Pharmaceutical Sciences, University of Copenhagen

2004-2006: Member of Academic Council, DUPS

2005-2007: Member of scientific committee, Dept. of Medicinal Chemistry, DUPS

2007-2011: Member of Academic Council, Faculty of Pharmaceutical Sciences, University of Copenhagen

2007: Appointed director of Drug Research Academy, an industry-oriented research education programme at the Faculty of Pharmaceutical Sciences, University of Copenhagen (August-October)

2007-2012: Director of Drug Research Academy, an industry-oriented research education programme at the Faculty of Pharmaceutical Sciences, University of Copenhagen

2008-2013: Head of GluTarget, project within the Programme of Excellence at the University of Copenhagen. 24.5 mio. kr. Project title: Ionotropic glutamate receptors as targets for structure-based drug research: A multidisciplinary programme in structural biology, chemical biology, medicinal chemistry, molecular pharmacology and ex vivo/in vivo pharmacology

2010-2012: Member of board, SHARE's Cross Faculty PhD Initiative, University of Copenhagen

2010-2012: Coordinator of mobility PhD grant on project “Ion channel receptors in brain diseases”

2012: Member of Academic Council, Faculty of Health and Medical Sciences, University of Copenhagen

2012-2018: Member of Research and Innovation Committee, Dept. of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen

2015-2020: Appointed Member of The Danish Council for Independent Research, Natural Sciences (FNU) by the Minister for Higher Education and Science

2016-2018: Member of the PIPPI Advisory Board, an Innovative Training Network (ITN) funded under the European Horizon 2020 programme, DTU.

2017-2020: Member of the Executive Committee, Independent Research Fund Denmark, Natural Sciences (FNU)

2019: Appointed Head of Research Cluster on Neuroprotection, ILF, KU (April-August)

2019-: Deputy Head of Department (ILF, KU) with focus on Research, from September

2019-: Head of Research Committee at ILF, KU, from September

Supervision of PhD students and post docs

• PhD students (32 since 1993, hereof 15 as main supervisor) and post docs (15 since 2005)
• Has been member and chairperson of several PhD committees

 

February 2022

Brief Teaching CV: Jette Sandholm Kastrup                                                                                    

Work address: Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, DK-2100 CPH Ø, Denmark

Phone: +45 3533 6486; E-mail: jsk@sund.ku.dk

Teaching at undergraduate courses 1988-2021

Introduction to study (1. semester: lectures, lab courses, project work, planning and evaluation)

Organic chemistry (1.-3. semester: teaching in class-room, lab courses, planning and evaluation)

Biochemistry (2. semester: lectures)

Bioorganic chemistry (3. semester: lectures)

Interdisciplinary course (5. semester: project work)

Basic drug design and discovery (6. or 7. semester: lectures, exams, planning and evaluation)

Bioinformatics and structural biology (7. semester: lectures, computer workshops, exams, planning and evaluation)

Medicinal and biostructural chemistry (7. semester: lectures, computer workshops, teaching in class-room, exams, planning and evaluation)

Structural chemistry (9. semester: lectures, computer workshops, project supervisions, exams, planning and evaluation)

Structural and computational medicinal chemistry (9. semester: lectures, computer workshops, project supervisions, planning and evaluation)

Individualized study unit 2018 (7.5 ECTS; Structural study of the GluA2 ligand-binding domain in complex with the allosteric modulator TDPAM01)

Individualized study unit 2018 (30 ECTS; Structural study of the GluA2 ligand-binding domain in complex with allosteric modulators named TDPAMs)

Individualized study unit 2019 (7.5 ECTS; Structural study of the GluA2 ligand-binding domain in complex with a positive allosteric modulator)

Teaching at PhD courses 1994-2021

Advanced Medicinal Chemistry and Drug Design, Royal Danish School of Pharmacy, 1994-1998 (lectures and workshop)

Cross-Institutional PhD Course on Molecular Biophysics, Royal Danish School of Pharmacy, 2000 (lecture)

Drug Design and Discovery, Royal Danish School of Pharmacy, 1999-2000 (lectures).

Protein Structure and Interaction, Panum Institute, 1995 (lecture)

Advanced Structural Chemistry and Molecular Modelling, Royal Danish School of Pharmacy, 1994-2001 and Danish University of Pharmaceutical Sciences, 2002-2007 (lectures, computer workshops, planning and evaluation)

Analytical Challenges in the Formulation Design of Pharmaceutical Proteins, Royal Danish School of Pharmacy, 2002 and Faculty of Pharmaceutical Sciences, University of Copenhagen 2007, 2009, 2011 and 2013 (lectures)

Biostructures and Molecular Modeling in Drug Research, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2008, 2009 and 2011 (lectures, computer workshops, planning and evaluation)

Receptor Structure and Function, Royal Danish School of Pharmacy, 1999-2001, Danish University of Pharmaceutical Sciences, 2002-2006, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2007-2011 and Faculty of Health and Medical Sciences, University of Copenhagen 2012-2021 (course director, lectures, workshops, exams, planning and evaluation)

Biostructures and Molecular Modeling in Drug Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2012-2017 (lectures; discussion facilitator in 2014)

Analytical Methodology in Protein Formulation Development, Faculty of Health and Medical Sciences, University of Copenhagen, 2018 and 2021 (lectures)

Scientific project planning and management 2 - Project and Career planning, Faculty of Health and Medical Sciences, University of Copenhagen, 2018 and 2019 (lectures)

Training of high school teachers in biotechnology 2010-2012

Course on Biostructure and Biofunction, 2010, 2011 and 2012 (in total 8 one-day courses including lectures, lab exercises, computer exercises, planning and evaluation – more than 200 teachers)

Research dissemination

”Lægemidler mod hjernens sygdomme”. Lectures offered to high school students.

Science in the city festival, Copenhagen June 2014: Science slammer and researcher at exhibition.

Examiner

- at several national and international BSc and MSc project work and Ph.D. defenses, 1997-2022.

Courses on pedagogy

Pedagogic Course, Royal Danish School of Pharmacy, June 1993

Mentor seminar, 2001

Course on supervision of PhD students (PUMA course 1562), University of Copenhagen, Nov. 2009

Course for academic advisors at LIFE, FARMA, SCIENCE AND HEALTH, Department of Science Education (DSE), Faculty of Science, University of Copenhagen, April 15, 2011

English language competence assessment for lecturers at FARMA, course at the Faculty of Pharmaceutical Sciences, University of Copenhagen, December 2011

Course on Responsible Conduct of Research for Academic Staff, University of Copenhagen, April 16, 2015

Course for Department Supervisors, Department of Science Education, KU, 2017

Course for Department Supervisors, Department of Science Education. KU, October 31, 2019

Participation in seminars on pedagogy arranged by the Royal Danish School of Pharmacy, the Danish University of Pharmaceutical Sciences and the University of Copenhagen

Committees

Member of committee for pedagogy/education, Royal Danish School of Pharmacy: 1996-1999

Member of IT political contact organ for university institutions: 1998

Mentor for pedagogy/education, Royal Danish School of Pharmacy: 2001-2002; Danish University of Pharmaceutical Sciences: 2002-2006; Faculty of Pharmaceutical Sciences, University of Copenhagen: 2007-2011; and Faculty of Health and Medical Sciences: 2012-2013, 2019; 2021-2022 (training on teaching as part of course for post docs/assistant professors)

Member of committee concerning toxicology and work environment, Royal Danish School of Pharmacy: 2000-2002

Member of committee concerning internship period at a community (or hospital) pharmacy, Danish University of Pharmaceutical Sciences: 2003