Jens Frederik Rehfeld

Jens Frederik Rehfeld

Professor

Member of:

  • Clinical Biochemistry


  1. 2024
  2. Published

    Colesevelam has no acute effect on postprandial GLP-1 levels but abolishes gallbladder refilling

    Gether, I. M., Bahne, E., Nerild, H. H., Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2024, In: European Journal of Endocrinology. 190, 4, p. 314-326 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer

    Nerild, H. H., Brønden, A., Haddouchi, A. E., Ellegaard, A., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 4, p. 1252-1263

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Suboptimal Weight Loss 13 Years After Roux-en-Y Gastric Bypass Is Associated with Blunted Appetite Response

    Nymo, S., Lundanes, J., Eriksen, K., Aukan, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Johnsen, G., Græslie, H., Kulseng, B., Sandvik, J. & Martins, C., 2024, In: Obesity Surgery. 34, 2, p. 592-601

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2023
  6. Published

    Association between Fat-Free Mass Loss, Changes in Appetite, and Weight Regain in Individuals with Obesity

    Martins, C., Nymo, S., Coutinho, S. R., Rehfeld, Jens Frederik, Hunter, G. R. & Gower, B. A., 2023, In: Journal of Nutrition. 153, 5, p. 1330-1337 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effects of levothyroxine substitution therapy on hunger and food intake in individuals with hypothyroidism

    Medici, B. R., Nygaard, Birte, la Cour, J. L., Krakauer, M., Brønden, Andreas, Sonne, M. P., Holst, Jens Juul, Rehfeld, Jens Frederik, Vilsbøll, Tina, Faber, J. & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 10, 14 p., e230314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery

    Aukan, M. I., Skårvold, S., Brandsaeter, I. Ø., Rehfeld, Jens Frederik, Holst, Jens Juul, Nymo, S., Coutinho, S. & Martins, C., 2023, In: Obesity. 31, 2, p. 399-411 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    History of key regulatory peptide systems and perspectives for future research

    Chen, D., Rehfeld, Jens Frederik, Watts, A. G., Rorsman, P. & Gundlach, A. L., 2023, In: Journal of Neuroendocrinology. 35, 11, 20 p., e13251.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Increased Meal Size but Reduced Meal-Stimulated Plasma Cholecystokinin Concentrations in Women With Obesity

    Geary, N., Asarian, L., Graf, G., Gobbi, S., Tobler, P. N., Rehfeld, Jens Frederik & Leeners, B., 2023, In: Endocrinology. 164, 1, 9 p., bqac192.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility

    Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Primary weight loss failure after Roux-en-Y gastric bypass is characterized by impaired gut-hormone mediated regulation of food intake

    Bojsen-Møller, Kirstine Nyvold, Svane, M. S., Martinussen, C., Dirksen, Carsten Moro, Jørgensen, Nils Bruun, Jensen, Jens-Erik Beck, Jensen, Christian Zinck, Torekov, Signe Sørensen, Kristiansen, V. B., Rehfeld, Jens Frederik, Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, 2023, In: International Journal of Obesity. 47, 11, p. 1143-1151 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine

    Gerstenberg, M. K., Andersen, Daniel Bjørklund, Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, Bolette, Rehfeld, Jens Frederik, Petersen, N., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2022
  15. Published

    Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial

    Hvistendahl, M. K., Naimi, R. M., Hansen, S. H., Rehfeld, Jens Frederik, Kissow, Hannelouise, Pedersen, Jens, Dragsted, Lars Ove, Sonne, D. P., Knop, Filip Krag & Jeppesen, Palle Bekker, 2022, In: Journal of Parenteral and Enteral Nutrition. 46, 4, p. 923-935 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Biochemistry of the Endocrine Heart

    Goetze, Jens P. , Bartels, Emil Daniel, Shalmi, T. W., Andraud‐dang, L. & Rehfeld, Jens Frederik, 2022, In: Biology. 11, 7, 971.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Differences in gastrointestinal hormones and appetite ratings among obesity classes: Gastrointestinal hormones and appetite in obesity

    Aukan, M. I., Nymo, S., Haagensli Ollestad, K., Akersveen Boyesen, G., DeBenedictis, J. N., Rehfeld, Jens Frederik, Coutinho, S. & Martins, C., 2022, In: Appetite. 171, 8 p., 105940.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effects of intraduodenal infusion of lauric acid and L-tryptophan, alone and combined, on glucoregulatory hormones, gastric emptying and glycaemia in healthy men

    Hajishafiee, M., McVeay, C., Lange, K., Rehfeld, Jens Frederik, Horowitz, M. & Feinle-Bisset, C., 2022, In: Metabolism: Clinical and Experimental. 129, 9 p., 155140.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Entero-pancreatic hormone secretion, gastric emptying and glucose absorption after frequently sampled meal tests

    Veedfald, Simon, Rehfeld, Jens Frederik, van Hall, Gerrit, Svendsen, Lars Bo & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. e188-e204 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Enterohepatic, gluco-metabolic, and gut microbial characterization of individuals with bile acid malabsorption

    Kårhus, M. L., Sonne, David Peick, Thomasen, M., Ellegaard, A., Holst, Jens Juul, Rehfeld, Jens Frederik, Chávez-Talavera, O., Tailleux, A., Staels, B., Nielsen, Dennis Sandris, Dragsted, Lars Ove, Vilsbøll, Tina, Brønden, A. & Knop, Filip Krag, 2022, In: Gastro Hep Advances. 1, 3, p. 299-312 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Erythritol and xylitol differentially impact brain networks involved in appetite regulation in healthy volunteers

    Meyer-Gerspach, A. C., Wingrove, J. O., Beglinger, C., Rehfeld, Jens Frederik, Le Roux, C. W., Peterli, R., Dupont, P., O’Daly, O., Van Oudenhove, L. & Wölnerhanssen, B. K., 2022, In: Nutritional Neuroscience. 25, 11, p. 2344-2358 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Gastric Aspiration Improves Postprandial Glucose Tolerance Without Causing a Compensatory Increase in Appetite and Food Intake

    Gether, I. M., Jensen, M. M., Nexøe-Larsen, C. C., Jorsal, T., Gasbjerg, Lærke Smidt, Naver, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Obesity Surgery. 32, p. 1385–1390

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Jan Fahrenkrug (6/6 1947 – 10/11 2021)

    Rehfeld, Jens Frederik, Hannibal, Jens, Holst, Jens Juul, Hökfelt, T., de Muckadell, O. B. S. & Schwartz, Thue W., 2022, In: Peptides. 150, 170771.

    Research output: Contribution to journalEditorialResearch

  24. Published

    Lipid emulsion interfacial design modulates human in vivo digestion and satiation hormone response

    Bertsch, P., Steingoetter, A., Arnold, M., Scheuble, N., Bergfreund, J., Fedele, S., Liu, D., Parker, H. L., Langhans, W., Rehfeld, Jens Frederik & Fischer, P., 2022, In: Food and Function. 13, 17, p. 9010-9020

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Oral Erythritol Reduces Energy Intake during a Subsequent ad libitum Test Meal: A Randomized, Controlled, Crossover Trial in Healthy Humans

    Teysseire, F., Flad, E., Bordier, V., Budzinska, A., Weltens, N., Rehfeld, Jens Frederik, Beglinger, C., Van Oudenhove, L., Wölnerhanssen, B. K. & Meyer-Gerspach, A. C., 2022, In: Nutrients. 14, 19, 15 p., 3918.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Quinine Effects on Gut and Pancreatic Hormones and Antropyloroduodenal Pressures in Humans-Role of Delivery Site and Sex

    Rezaie, P., Bitarafan, V., Rose, B. D., Lange, K., Rehfeld, Jens Frederik, Horowitz, M. & Feinle-Bisset, C., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 7, p. E2870-E2881

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Resting and postpradial serum cholecystokinin concentrations and evaluation of the effect of seeing and/or smelling food on serum cholecystokinin and bile acid concentrations in healthy dogs

    Xenoulis, P. G., Karra, D. A., Aicher, K. M., Rehfeld, Jens Frederik, Suchodolski, J. S., Read, S. A. & Steiner, J. M., 2022, In: Research in Veterinary Science. 151, p. 110-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The Role of D-allulose and Erythritol on the Activity of the Gut Sweet Taste Receptor and Gastrointestinal Satiation Hormone Release in Humans: A Randomized, Controlled Trial

    Teysseire, F., Bordier, V., Budzinska, A., Weltens, N., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Beglinger, C., Van Oudenhove, L., Wölnerhanssen, B. K. & Meyer-Gerspach, A. C., 2022, In: Journal of Nutrition. 152, 5, p. 1228–1238,

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation

    Vana, V., Lærke, M. K., Rehfeld, Jens Frederik, Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, Thue W. & Hansen, Harald S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2021
  32. Published

    Gastrin and the moderate hypergastrinemias

    Rehfeld, Jens Frederik, 1 Jul 2021, In: International Journal of Molecular Sciences. 22, 13, 12 p., 6977.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    The endocrine effects of bitter tastant administration in the gastrointestinal system: intragastric versus intraduodenal administration

    Verbeure, W., Deloose, E., Tóth, J., Rehfeld, Jens Frederik, Van Oudenhove, L., Depoortere, I. & Tack, J., 1 Jul 2021, In: American journal of physiology. Endocrinology and metabolism. 321, 1, p. E1-E10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    On premises and principles for measurement of gastrointestinal peptide hormones

    Albrechtsen, Nicolai Jacob Wewer & Rehfeld, Jens Frederik, Jul 2021, In: Peptides. 141, 11 p., 170545.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Association between habitual sleep duration/quality and appetite markers in individuals with obesity

    Nymo, S., Kleppe, M. M., Coutinho, S. R., Rehfeld, Jens Frederik, Kulseng, B. & Martins, C., 1 Apr 2021, In: Physiology and Behavior. 232, 6 p., 113345.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Chromogranin A in cardiovascular endocrinology

    Goetze, Jens P. , Hilsted, L. M. & Rehfeld, Jens Frederik, Apr 2021, In: Acta Physiologica. 231, 4, 3 p., e13615.

    Research output: Contribution to journalEditorialResearchpeer-review

  37. Published

    PROCESSING-INDEPENDENT ANALYSIS (PIA): A METHOD FOR QUANTITATION OF THE TOTAL PEPTIDE-GENE EXPRESSION

    Rehfeld, Jens Frederik & Goetze, J. P., Jan 2021, In: Peptides. 135, 8 p., 170427.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Acute ketosis inhibits appetite and decreases plasma concentrations of acyl ghrelin in healthy humans

    Vestergaard, E. T., Zubanovic, N. B., Rittig, N., Møller, N., Kuhre, Rune Ehrenreich, Holst, Jens Juul, Rehfeld, Jens Frederik & Thomsen, H. H., 2021, In: Diabetes, Obesity and Metabolism. 23, 8, p. 1834-1842

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Cholecystokinin and panic disorder: Reflections on the history and some unsolved questions

    Rehfeld, Jens Frederik, 2021, In: Molecules. 26, 18, 5657.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Cholecystokinin and the hormone concept

    Rehfeld, Jens Frederik, 2021, In: Endocrine Connections. 10, 3, p. R139-R150 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Effect of the natural sweetener xylitol on gut hormone secretion and gastric emptying in humans: A pilot dose-ranging study

    Meyer-Gerspach, A. C., Drewe, J., Verbeure, W., Le Roux, C. W., Dellatorre-Teixeira, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Tack, J., Peterli, R., Beglinger, C. & Wölnerhanssen, B. K., 2021, In: Nutrients. 13, 1, 21 p., 174.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass

    Jonsson, I., Bojsen-Moller, K. N., Kristiansen, V. B., Veedfald, Simon, Albrechtsen, Nicolai Jacob Wewer, Clausen, T. R., Kuhre, Rune Ehrenreich, Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Svane, M. S., 2021, In: Frontiers in Endocrinology. 12, 11 p., 681116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Effects of carbohydrate restriction on postprandial glucose metabolism, β-cell function, gut hormone secretion, and satiety in patients with type 2 diabetes

    Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten, Burling, K., Fenger, M., Thomsen, M. N., Larsen, T. M., Krarup, T. & Haugaard, Steen Bendix, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 1, p. E7-E18 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Expression of Cholecystokinin and its Receptors in the Intestinal Tract of Type 2 Diabetes Patients and Healthy Controls

    Gilliam-Vigh, H., Jorsal, T., Rehfeld, Jens Frederik, Pedersen, Jens, Poulsen, Steen Seier, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 8, p. 2164-2170 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Gastric emptying of solutions containing the natural sweetener erythritol and effects on gut hormone secretion in humans: A pilot dose-ranging study

    Wolnerhanssen, B. K., Drewe, J., Verbeure, W., le Roux, C. W., Dellatorre-Teixeira, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Tack, J., Peterli, R., Beglinger, C. & Meyer-Gerspach, A. C., 2021, In: Diabetes, Obesity and Metabolism. 23, 6, p. 1311-1321

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Liraglutide decreases postprandial fibroblast growth factor 19 and glucagon-like peptide 2, and increases postprandial cholecystokinin in individuals with obesity

    Bronden, A., Nerild, H. H., Nexoe-Larsen, C. C., Hellmann, P. H., Baekdal, M., Gether, I. M., Gillum, M. P., Hartmann, Bolette, Knudsen, L. B., Jacobsen, L. V., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 94-94 177.

    Research output: Contribution to journalConference abstract in journalResearch

  47. Published

    Post-oral fat-induced satiation is mediated by endogenous CCK and GLP-1 in a fat self-administration mouse model

    Vana, V., Lærke, M. K., Kleberg, K., Mroz, P. A., Lindberg, B. L., Ekberg, J. H., Rehfeld, Jens Frederik, Schwartz, Thue W. & Hansen, Harald S., 2021, In: Physiology and Behavior. 234, 12 p., 113315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Hansen, L. S., Hansen, N. L., Stensen, S., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: European Journal of Endocrinology. 184, 3, p. 387-398 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2020
  50. Published

    Circadian variations in plasma concentrations of cholecystokinin and gastrin in man

    Rehfeld, Jens Frederik, Sennels, H. P., Jørgensen, Henrik Løvendahl & Fahrenkrug, J., 2 Nov 2020, In: Scandinavian Journal of Clinical and Laboratory Investigation. 80, 7, p. 546-551 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    The relationship between cholecystokinin secretion and pancreatic [11C]methionine uptake in patients after partial pancreaticoduodenectomy

    Steiner, E., Kazianka, L., Breuer, R., Hacker, M., Wadsak, W., Mitterhauser, M., Rehfeld, Jens Frederik, Karanikas, G. & Miholic, J., Sep 2020, In: Annals of Nuclear Medicine. 34, 9, p. 691-695 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  52. Published

    The GLP-1 receptor agonist lixisenatide reduces postprandial glucose in patients with diabetes secondary to total pancreatectomy: a randomised, placebo-controlled, double-blinded crossover trial

    Juel, C. T. B., Lund, A., Andersen, M. M., Hansen, C. P., Storkholm, J. H., Rehfeld, Jens Frederik, van Hall, G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2020, In: Diabetologia. 63, p. 1285-1298

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Association Between Ketosis and Changes in Appetite Markers with Weight Loss Following a Very Low-Energy Diet

    Martins, C., Nymo, S., Truby, H., Rehfeld, Jens Frederik, Hunter, G. R. & Gower, B. A., 2020, In: Obesity. 28, 12, p. 2331-2338

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy

    Eiken, A., Fuglsang, S., Eiken, M., Svane, M. S., Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hansen, S. H., Trammell, Sam, Svenningsen, J. S., Rehfeld, Jens Frederik, Bojsen-Møller, K. N., Jørgensen, N. B., Holst, Jens Juul, Madsbad, Sten, Madsen, J. L. & Dirkse, C., 2020, In: International Journal of Obesity. 44, p. 1872-1883

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published
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ID: 3844