Jan Stenvang

Jan Stenvang

Associate Professor


  1. 2013
  2. Published

    TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells

    Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V. & 1 others, Stenvang, Jan, 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    A systematic review on topoisomerase 1 inhibition in the treatment of metastatic breast cancer

    Kümler, I., Brünner, N., Stenvang, Jan, Balslev, E. & Nielsen, D. L., 2013, In: Breast Cancer Research and Treatment. 138, 2, p. 347-358 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development

    Stenvang, Jan, Kümler, I., Nygård, S. B., Smith, D. H., Nielsen, D., Brünner, N. & Moreira, José, 2013, In: Frontiers in Oncology. 3, 9 p., 313.

    Research output: Contribution to journalReviewpeer-review

  5. Published

    High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer

    Rasmussen, M. H., Jensen, N. F., Tarpgaard, L. S., Qvortrup, C., Rømer, M. U. K., Stenvang, Jan, Hansen, T. P., Christensen, L. L., Lindebjerg, J., Hansen, F., Jensen, B. V., Hansen, T. F., Pfeiffer, P., Brünner, N., Ørntoft, T. F. & Andersen, C. L., 2013, In: Molecular Oncology. 7, 3, p. 637-646 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

    Lin, X., Li, J., Yin, G., Zhao, Q., Elias, D., Lykkesfeldt, A., Stenvang, Jan, Brünner, N., Wang, J., Yang, H., Bolund, L. & Ditzel, H. J., 2013, In: Breast cancer research : BCR. 15, 6, 17 p., R119.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study

    Thorsen, S. B., Christensen, S. L. T., Würtz, S. Ø., Lundberg, M., Nielsen, B. E. S., Jensen, L. V., Knowles, M., Gee, N., Fredriksson, S., Møller, S., Brünner, N., Rasmussen, A. S. & Stenvang, Jan, 2013, In: B M C Cancer. 13, 12 p., 598.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Proximity probing assays for simultaneous visualization of protein complexes in situ

    Moreira, José, Thorsen, S. B., Brünner, N. & Stenvang, Jan, 2013, In: Expert Review of Proteomics. 10, 3, p. 219-221 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    TIMP-1 overexpression does not affect sensitivity to HER2-targeting drugs in the HER2-gene-amplified SK-BR-3 human breast cancer cell line

    Deng, X., Fogh, L., Lademann, U. A., Jensen, V., Stenvang, Jan, Yang, H., Brünner, N. & Rasmussen, A. S., 2013, In: Tumor Biology. 34, 2, p. 1161-1170 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression

    Bjerre, C. A., Jensen, L. V., Belling, K. C., Würtz, S. Ø., Yadav, R., Lademann, U. A., Rigina, O., Do, K. N., Ditzel, H. J., Lykkesfeldt, A. E., Wang, J., Nielsen, H. B., Brünner, N., Gupta, R., Rasmussen, A. S. & Stenvang, Jan, 2013, In: Tumor Biology. 34, 6, p. 3839-3851 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. 2012
  12. Published

    Inhibition of microRNA function by antimiR oligonucleotides

    Stenvang, Jan, Petri, A., Lindow, M., Obad, S. & Kauppinen, S., 2012, In: Silence. 3, 1, 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    The therapeutic potential of MicroRNAs in cancer

    Thorsen, S. B., Obad, S., Jensen, N. F., Stenvang, Jan & Kauppinen, S., 2012, In: Cancer Journal. 18, 3, p. 275-284 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. 2011
  15. Published

    MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo

    Eskildsen, T., Taipaleenmäki, H., Stenvang, Jan, Abdallah, B., Ditzel, N., Nossent, Anne Yaël, Bak, M., Kauppinen, S. & Kassem, M., 12 Apr 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 15, p. 6139-44 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Multiplexed homogeneous proximity ligation assays for high throughput protein biomarker research in serological material

    Lundberg, M., Thorsen, S. B., Assarsson, E., Villablanca, A., Tran, B., Gee, N., Knowles, M., Nielsen, B. E. S., Couto, E. G., Martin, R., Nilsson, O., Fermer, C., Schlingemann, J., Christensen, I. J., Nielsen, H. J., Ekstrom, B., Andersson, C., Gustafsson, M., Brünner, N., Stenvang, J. & 1 others, Fredriksson, S., Apr 2011, In: Molecular and Cellular Proteomics. 10

    Research output: Contribution to journalJournal articlepeer-review

  17. Submitted

    MicroRNA profiling in generated oxaliplatin- and SN-38-resistant colorectal cancer cell lines

    Jensen, N. F., Søkilde, R., Stenvang, Jan, Litman, T., Brunner, N. & Rømer, M. U. K., 2011, (Submitted). 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  18. Silencing of microRNA families by seed-targeting tiny LNAs

    Obad, S., dos Santos, C. O., Petri, A., Heidenblad, M., Broom, O., Ruse, C., Fu, C., Lindow, M., Stenvang, Jan, Straarup, E. M., Hansen, H. F., Koch, T., Pappin, D., Hannon, G. J. & Kauppinen, S., 2011, In: Nature Genetics. 43, 4, p. 371-8 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. 2010
  20. MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte–associated antigen 4

    Sonkoly , E., Janson , P., Majuri , M., Savinko , T., Fyhrquist , N., Eidsmo , L., Xu , N., Meisgen , F., Wei , T., Bradley , M., Stenvang, Jan, Kauppinen , S., Alenius, H., Lauerma , A., Homey , B., Winqvist , O., Ståhle , M. & Pivarcsi , A., 2010, In: Journal of Allergy and Clinical Immunology. 126, 3, p. 581-589.e20 29 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    MicroRNAs, epigenetics and disease

    Silahtaroglu, Asli & Stenvang, Jan, 2010, In: Essays in Biochemistry. 48, 1, p. 165-185 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. 2008
  23. Published

    MicroRNAs as targets for antisense-based therapeutics

    Stenvang, Jan & Kauppinen, M. S., 2008, In: Expert Opinion on Biological Therapy. 8, 1, p. 59-81 22 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Targeting of microRNAs for therapeutics

    Stenvang, Jan, Lindow, M. & Kauppinen, S., 2008, In: Biochemical Society Transactions. 36, Pt 6, p. 1197-200 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    The utility of LNA in microRNA-based cancer diagnostics and therapeutics

    Stenvang, Jan, Silahtaroglu, Asli, Lindow, M., Elmen, J. & Kauppinen, S., 2008, In: Seminars in Cancer Biology. 18, 2, p. 89-102 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. 2007
  27. Published

    Breast cancer cells with acquired antiestrogen resistance are sensitized to cisplatin-induced cell death

    Yde, C. W., Gyrd-Hansen, Mads, Lykkesfeldt, A. E., Issinger, O. & Stenvang, Jan, Jun 2007, In: Molecular Cancer Therapeutics. 6, 6, p. 1869-1876 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer

    Rasmussen, L. M., Zaveri, N. T., Stenvang, Jan, Peters, R. H. & Lykkesfeldt, A. E., 2007, In: Breast Cancer Research and Treatment. 106, 2, p. 191-203 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT

    Yde, C. W., Frogne, T., Lykkesfeldt, A. E., Fichtner, I., Issinger, O. G. & Stenvang, Jan, 2007, In: Cancer Letters. 256, 2, p. 229-237 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Protein kinase C alpha is a marker for antiestrogen resistance and is involved in the growth of tamoxifen resistant human breast cancer cells

    Frankel, Lisa, Lykkesfeldt, A. E., Hansen, J. B. H. & Stenvang, Jan, 2007, In: Breast Cancer Research and Treatment. 104, 2, p. 165-179 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. 2006
  32. Published

    Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator

    Juncker-Jensen, A., Lykkesfeldt, A. E., Worm, J., Ralfkiær, U., Espelund, U. & Stenvang, Jan, 1 Aug 2006, In: Growth Hormone and IGF Research. 16, 4, p. 224-239 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. 2005
  34. Synthesis and biological evaluation of branched and conformationally restricted analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Andersen, N. K., Stenvang, Jan, Hansen, F. G., Haselmann, K. F., Nielsen, C. & Wengel, J., 1 Apr 2005, In: Bioorganic & Medicinal Chemistry. 13, 7, p. 2597-621 25 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Jepsen, J. S., Nielsen, C., Wengel, J. & Stenvang, Jan, 15 Feb 2005, In: Bioorganic & Medicinal Chemistry. 13, 4, p. 1249-60 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Synthesis and biological evaluation of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Stenvang, Jan & Wengel, J., 2005, In: Nucleosides, nucleotides & nucleic acids. 24, 5-7, p. 397-400 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. 2004
  38. LNA-antisense rivals siRNA for gene silencing

    Stenvang, Jan & Wengel, J., Mar 2004, In: Current Opinion in Drug Discovery & Development. 7, 2, p. 188-94 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. Downregulation of p21(WAF1/CIP1) and estrogen receptor alpha in MCF-7 cells by antisense oligonucleotides containing locked nucleic acid (LNA)

    Stenvang, Jan, Pfundheller, H. M. & Lykkesfeldt, A. E., 2004, In: Oligonucleotides. 14, 2, p. 147-56 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Locked nucleic acid: a potent nucleic acid analog in therapeutics and biotechnology

    Stenvang, Jan, Sørensen, M. D. & Wengel, J., 2004, In: Oligonucleotides. 14, 2, p. 130-46 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Modulation of CpG oligodeoxynucleotide-mediated immune stimulation by locked nucleic acid (LNA)

    Vollmer, J., Uhlmann, E., Stenvang, Jan, Schetter, C., Jurk, M., Wader, T., Wüllner, M. & Krieg, A. M., 2004, In: Oligonucleotides. 14, 1, p. 23-31 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Sequential versus combined treatment of human breast cancer cells with antiestrogens and the vitamin D analogue EB1089 and evaluation of predictive markers for vitamin D treatment.

    Christensen, G. L., Stenvang, Jan, Fog, C. K., Christensen, I. J. & Lykkesfeldt, A. E., 2004, In: Breast Cancer Research and Treatment. p. 53–63

    Research output: Contribution to journalJournal articlepeer-review

  43. 1999
  44. Published

    Conserved residues and their role in the structure, function, and stability of acyl-coenzyme A binding protein

    Kragelund, B. B., Poulsen, K., Andersen, K. V., Baldursson, T., Krøll, J. B., Neergård, T. B., Jepsen, J., Roepstorff, P., Kristiansen, Karsten, Poulsen, F. M., Knudsen, J. & Stenvang, Jan, 1999, In: Biochemistry. 38, 8, p. 2386-94 9 p.

    Research output: Contribution to journalJournal articlepeer-review

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