Jan Stenvang

Jan Stenvang

Associate Professor


  1. 2016
  2. Published

    Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment

    Ellegaard, A., Dehlendorff, C., Vind, Anna Constance, Anand, A., Kristiansen, Luise Cederkvist, Petersen, N. H. T., Nylandsted, J., Stenvang, Jan, Mellemgaard, A., Osterlind, K., Friis, S. & Jaattela, Marja, Jul 2016, In: EBioMedicine. 9, p. 130-139 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

    Hansen, S. N., Ehlers, Natasja Spring, Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, José, Ditzel, H. J., Brünner, N., Rasmussen, A. S., Stenvang, Jan & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue

    Karlsson, Camilla Cederbye, Palshof, J. A., Kuhlmann, Tine Plato, Duun-Henriksen, A. K., Linnemann, D., Stenvang, Jan, Nielsen, Dorte Lisbet, Brunner, N. & Viuff, B. M., 3 Jun 2016, In: Scientific Reports. 6, 16 p., 26997.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines

    Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, Rasmussen, A. S. & Stenvang, Jan, 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification

    Tarpgaard, L. S., Qvortrup, C., Nygård, S. B., Nielsen, Signe Lykke, Andersen, D. R., Jensen, N. F., Stenvang, Jan, Detlefsen, S., Brünner, N. & Pfeiffer, P., 2016, In: B M C Cancer. 16, 5 p., 91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations

    Jensen, N. F., Agama, K., Roy, A., Smith, D. H., Pfister, T. D., Rømer, M. U., Zhang, H., Doroshow, J. H., Knudsen, B. R., Stenvang, Jan, Brünner, N. & Pommier, Y., 2016, In: Journal of Experimental and Clinical Cancer Research (Online). 35, 14 p., 56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Drug resistance in colorectal cancer cell lines is partially associated with aneuploidy status in light of profiling gene expression

    Guo, J., Xu, S., Huang, X., Li, L., Zhang, C., Pan, Q., Ren, Z., Zhou, R., Ren, Y., Zi, J., Wu, L., Stenvang, Jan, Brünner, N., Wen, B. & Liu, S., 2016, In: Journal of Proteome Research. 15, 11, p. 4047–4059 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer

    Joshi, T., Elias, D., Stenvang, Jan, Alves, C. M. L., Teng, F., Lyng, M. B., Lykkesfeldt, A. E., Brünner, N., Wang, J., Gupta, R., Workman, C. T. & Ditzel, H. J., 2016, In: OncoTarget. 7, 35, p. 57239-57253 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer

    Ostenfeld, M. S., Jensen, S. G., Jeppesen, D. K., Christensen, L., Thorsen, S. B., Stenvang, Jan, Hvam, M. L., Thomsen, A., Mouritzen, P., Rasmussen, M. H., Nielsen, H. J., Ørntoft, T. F. & Andersen, C. L., 2016, In: Journal of Extracellular Vesicles. 5, 14 p., 31488.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2015
  12. Published

    Drug transporters in breast cancer: response to anthracyclines and taxanes

    Kümler, I., Stenvang, Jan, Moreira, José, Brünner, N. & Nielsen, Dorte Lisbet, Sep 2015, In: Expert Review of Anticancer Therapy. 15, 9, p. 1075-1092 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer

    Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, N. & Stenvang, Jan, 8 Apr 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers

    Sønderstrup, I. M. H., Nygård, S. B., Poulsen, T. S., Linnemann, D., Stenvang, Jan, Nielsen, H. J., Bartek, J., Brünner, N., Nørgaard, P. & Riis, Lene Buhl, 4 Mar 2015, In: Molecular Oncology. 9, 6, p. 1207-1217 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Establishment and characterization of models of chemotherapy resistance in colorectal cancer: towards a predictive signature of chemoresistance

    Jensen, N. F., Stenvang, J., Beck, M. K., Hanáková, B., Belling, K. C., Do, K. N., Viuff, B. M., Nygård, S. B., Gupta, R., Rasmussen, M. H., Tarpgaard, L. S., Hansen, T. P., Budinská, E., Pfeiffer, P., Bosman, F., Tejpar, S., Roth, A., Delorenzi, M., Andersen, C. L., Rømer, M. U. K. & 2 others, Brünner, N. & Moreira, José, 24 Feb 2015, In: Molecular Oncology. 9, 6, p. 1169-1185 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol

    Kümler, Iben, Balslev, E., Stenvang, Jan, Brünner, N. & Nielsen, D., 2015, In: B M C Cancer. 15, 5 p., 78.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

    Hansen, S. N., Westergaard, David, Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, K. G., Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, José, Brünner, N., Stenvang, Jan & Rasmussen, A. S., 2015, In: Tumor Biology. 36, 6, p. 4327-4338 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Identification and characterization of a new TIMP-1 binding protein

    Moreira, José, Høeberg, M., Lademann, U. A., Viuff, B. M., Jensen, L. V., Stenvang, Jan, Nygård, S. B., Ørum-Madsen, M. S., Vistesen, M. V., Fuglsang, Anja Thoe, Liu, S. & Brünner, N., 2015, In: Cancer Research. 75, 9 suppl., 1 p., Abstract P5-07-08.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  19. Published

    TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas

    Grunnet, M., Calatayud, D., Schultz, N. A., Hasselby, Jane Preuss, Mau-Sørensen, M., Brünner, N. & Stenvang, Jan, 2015, In: Scandinavian Journal of Gastroenterology. 50, 4, p. 485-494 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

    Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer

    Lin, X., Stenvang, Jan, Rasmussen, M. H., Zhu, S., Jensen, N. F., Tarpgaard, L. S., Yang, G., Belling, K., Andersen, C. L., Li, J., Bolund, L. & Brünner, N., 2015, In: BMC Genomics. 16, 17 p., 404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2014
  23. Published

    Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability

    Assarsson, E., Lundberg, M., Holmquist, G., Björkesten, J., Thorsen, S. B., Ekman, D., Eriksson, A., Rennel Dickens, E., Ohlsson, S., Edfeldt, G., Andersson, A., Lindstedt, P., Stenvang, Jan, Gullberg, M. & Fredriksson, S., 2014, In: PLOS ONE. 9, 4, 11 p., e95192.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody

    Smith, D. H., Fiehn, A. K., Fogh, L., Christensen, I. J., Hansen, T. P., Stenvang, Jan, Nielsen, H. J., Nielsen, K. V., Hasselby, J. P., Brünner, N. & Jensen, S. S., 2014, In: Scientific Reports. 4, p. 1-8 8 p., 4313.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    No effect of ablation of surfactant protein-D on acute cerebral infarction in mice

    Lambertsen, K. L., Østergaard, K., Clausen, B. H., Hansen, S., Stenvang, Jan, Thorsen, S. B., Meldgaard, M., Kristensen, B. W., Hansen, P. B. L., Sørensen, G. L. & Finsen, B., 2014, In: Journal of Neuroinflammation. 11, 13 p., 123.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma

    Guil-Luna, S., Stenvang, Jan, Brünner, N., De Andrés, F. J., Rollón, E., Domingo, V., Sánchez-Céspedes, R., Millán, Y. & Mulas, J. M. D. L., 2014, In: B M C Veterinary Research. 10, 8 p., 296.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Progesterone receptor isoform analysis by quantitative real-time polymerase chain reaction in formalin-fixed, paraffin-embedded canine mammary dysplasias and tumors

    Guil-Luna, S., Stenvang, Jan, Brünner, N., Sánchez-Céspedes, R., Millán, Y., Gómez-Laguna, J. & Mulas, J. M. D. L., 2014, In: Veterinary Pathology. 51, 5, p. 895-902 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells

    Jensen, L. V., Lademann, U. A., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B. M., Brünner, N., Stenvang, Jan & Moreira, José, 2014, In: Protein Expression and Purification. 101, p. 157-164 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 12922