Jan Stenvang
Associate Professor
Translational and Clinical Pharmacology
Jagtvej 160
2100 København Ø
- 2016
- Published
Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment
Ellegaard, A., Dehlendorff, C., Vind, Anna Constance, Anand, A., Kristiansen, Luise Cederkvist, Petersen, N. H. T., Nylandsted, J., Stenvang, Jan, Mellemgaard, A., Osterlind, K., Friis, S. & Jaattela, Marja, Jul 2016, In: EBioMedicine. 9, p. 130-139 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
Hansen, S. N., Ehlers, Natasja Spring, Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, José, Ditzel, H. J., Brünner, N., Rasmussen, A. S., Stenvang, Jan & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue
Karlsson, Camilla Cederbye, Palshof, J. A., Kuhlmann, Tine Plato, Duun-Henriksen, A. K., Linnemann, D., Stenvang, Jan, Nielsen, Dorte Lisbet, Brunner, N. & Viuff, B. M., 3 Jun 2016, In: Scientific Reports. 6, 16 p., 26997.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines
Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, , 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification
Tarpgaard, L. S., Qvortrup, C., Nygård, S. B., Nielsen, Signe Lykke, Andersen, D. R., Jensen, N. F., Stenvang, Jan, Detlefsen, S., Brünner, N. & Pfeiffer, P., 2016, In: B M C Cancer. 16, 5 p., 91.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations
Jensen, N. F., Agama, K., Roy, A., Smith, D. H., Pfister, T. D., Rømer, M. U., Zhang, H., Doroshow, J. H., Knudsen, B. R., Stenvang, Jan, Brünner, N. & Pommier, Y., 2016, In: Journal of Experimental and Clinical Cancer Research (Online). 35, 14 p., 56.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug resistance in colorectal cancer cell lines is partially associated with aneuploidy status in light of profiling gene expression
Guo, J., Xu, S., Huang, X., Li, L., Zhang, C., Pan, Q., Ren, Z., Zhou, R., Ren, Y., Zi, J., Wu, L., Stenvang, Jan, Brünner, N., Wen, B. & Liu, S., 2016, In: Journal of Proteome Research. 15, 11, p. 4047–4059 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer
Joshi, T., Elias, D., Stenvang, Jan, Alves, C. M. L., Teng, F., Lyng, M. B., Lykkesfeldt, A. E., Brünner, N., Wang, J., Gupta, R., Workman, C. T. & Ditzel, H. J., 2016, In: OncoTarget. 7, 35, p. 57239-57253 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer
Ostenfeld, M. S., Jensen, S. G., Jeppesen, D. K., Christensen, L., Thorsen, S. B., Stenvang, Jan, Hvam, M. L., Thomsen, A., Mouritzen, P., Rasmussen, M. H., Nielsen, H. J., Ørntoft, T. F. & Andersen, C. L., 2016, In: Journal of Extracellular Vesicles. 5, 14 p., 31488.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Drug transporters in breast cancer: response to anthracyclines and taxanes
Kümler, I., Stenvang, Jan, Moreira, José, Brünner, N. & Nielsen, Dorte Lisbet, Sep 2015, In: Expert Review of Anticancer Therapy. 15, 9, p. 1075-1092 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer
Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, N. & Stenvang, Jan, 8 Apr 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers
Sønderstrup, I. M. H., Nygård, S. B., Poulsen, T. S., Linnemann, D., Stenvang, Jan, Nielsen, H. J., Bartek, J., Brünner, N., Nørgaard, P. & Riis, Lene Buhl, 4 Mar 2015, In: Molecular Oncology. 9, 6, p. 1207-1217 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Establishment and characterization of models of chemotherapy resistance in colorectal cancer: towards a predictive signature of chemoresistance
Jensen, N. F., Stenvang, J., Beck, M. K., Hanáková, B., Belling, K. C., Do, K. N., Viuff, B. M., Nygård, S. B., Gupta, R., Rasmussen, M. H., Tarpgaard, L. S., Hansen, T. P., Budinská, E., Pfeiffer, P., Bosman, F., Tejpar, S., Roth, A., Delorenzi, M., Andersen, C. L., Rømer, M. U. K. & 2 others, , 24 Feb 2015, In: Molecular Oncology. 9, 6, p. 1169-1185 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol
Kümler, Iben, Balslev, E., Stenvang, Jan, Brünner, N. & Nielsen, D., 2015, In: B M C Cancer. 15, 5 p., 78.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways
Hansen, S. N., Westergaard, David, Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, K. G., Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, José, Brünner, N., Stenvang, Jan & Rasmussen, A. S., 2015, In: Tumor Biology. 36, 6, p. 4327-4338 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of a new TIMP-1 binding protein
Moreira, José, Høeberg, M., Lademann, U. A., Viuff, B. M., Jensen, L. V., Stenvang, Jan, Nygård, S. B., Ørum-Madsen, M. S., Vistesen, M. V., Fuglsang, Anja Thoe, Liu, S. & Brünner, N., 2015, In: Cancer Research. 75, 9 suppl., 1 p., Abstract P5-07-08.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas
Grunnet, M., Calatayud, D., Schultz, N. A., Hasselby, Jane Preuss, Mau-Sørensen, M., Brünner, N. & Stenvang, Jan, 2015, In: Scandinavian Journal of Gastroenterology. 50, 4, p. 485-494 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells
Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer
Lin, X., Stenvang, Jan, Rasmussen, M. H., Zhu, S., Jensen, N. F., Tarpgaard, L. S., Yang, G., Belling, K., Andersen, C. L., Li, J., Bolund, L. & Brünner, N., 2015, In: BMC Genomics. 16, 17 p., 404.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability
Assarsson, E., Lundberg, M., Holmquist, G., Björkesten, J., Thorsen, S. B., Ekman, D., Eriksson, A., Rennel Dickens, E., Ohlsson, S., Edfeldt, G., Andersson, A., Lindstedt, P., Stenvang, Jan, Gullberg, M. & Fredriksson, S., 2014, In: PLOS ONE. 9, 4, 11 p., e95192.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody
Smith, D. H., Fiehn, A. K., Fogh, L., Christensen, I. J., Hansen, T. P., Stenvang, Jan, Nielsen, H. J., Nielsen, K. V., Hasselby, J. P., Brünner, N. & Jensen, S. S., 2014, In: Scientific Reports. 4, p. 1-8 8 p., 4313.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No effect of ablation of surfactant protein-D on acute cerebral infarction in mice
Lambertsen, K. L., Østergaard, K., Clausen, B. H., Hansen, S., Stenvang, Jan, Thorsen, S. B., Meldgaard, M., Kristensen, B. W., Hansen, P. B. L., Sørensen, G. L. & Finsen, B., 2014, In: Journal of Neuroinflammation. 11, 13 p., 123.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma
Guil-Luna, S., Stenvang, Jan, Brünner, N., De Andrés, F. J., Rollón, E., Domingo, V., Sánchez-Céspedes, R., Millán, Y. & Mulas, J. M. D. L., 2014, In: B M C Veterinary Research. 10, 8 p., 296.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Progesterone receptor isoform analysis by quantitative real-time polymerase chain reaction in formalin-fixed, paraffin-embedded canine mammary dysplasias and tumors
Guil-Luna, S., Stenvang, Jan, Brünner, N., Sánchez-Céspedes, R., Millán, Y., Gómez-Laguna, J. & Mulas, J. M. D. L., 2014, In: Veterinary Pathology. 51, 5, p. 895-902 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells
Jensen, L. V., Lademann, U. A., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B. M., Brünner, N., Stenvang, Jan & Moreira, José, 2014, In: Protein Expression and Purification. 101, p. 157-164 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12922
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1956
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MicroRNAs, epigenetics and disease
Research output: Contribution to journal › Journal article › Research › peer-review
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Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody
Research output: Contribution to journal › Journal article › Research › peer-review
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1390
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Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
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