Jan Stenvang

Jan Stenvang

Associate Professor

ORCID: 0000-0001-5647-4828

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  1. Published

    miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer

    Ostenfeld, M. S., Jensen, S. G., Jeppesen, D. K., Christensen, L., Thorsen, S. B., Stenvang, Jan, Hvam, M. L., Thomsen, A., Mouritzen, P., Rasmussen, M. H., Nielsen, H. J., Ørntoft, T. F. & Andersen, C. L., 2016, In: Journal of Extracellular Vesicles. 5, 14 p., 31488.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    lncRNA profile study reveals the mRNAs and lncRNAs associated with docetaxel resistance in breast cancer cells

    Huang, P., Li, F., Li, L., You, Y., Luo, S., Dong, Z., Gao, Q., Wu, S., Brünner, N. & Stenvang, Jan, 1 Dec 2018, In: Scientific Reports. 8, 1, 17970.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase i gene

    Kümler, I., Balslev, E., Stenvang, Jan, Brünner, N., Ejlertsen, Bent Laursen, Jakobsen, E. H. & Nielsen, D. L., Jun 2019, In: BMC Cancer. 19, 5 p., 573.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer

    Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, N. & Stenvang, Jan, 8 Apr 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers

    Sønderstrup, I. M. H., Nygård, S. B., Poulsen, T. S., Linnemann, D., Stenvang, Jan, Nielsen, H. J., Bartek, J., Brünner, N., Nørgaard, P. & Riis, Lene Buhl, 4 Mar 2015, In: Molecular Oncology. 9, 6, p. 1207-1217 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer

    Palshof, J. A., Høgdall, Estrid Vilma Solyom, Poulsen, T. S., Linnemann, D., Jensen, B. V., Pfeiffer, P., Tarpgaard, L. S., Brunner, N., Stenvang, Jan, Yilmaz, M. & Nielsen, Dorte Lisbet, 11 Jan 2017, In: BMC Cancer. 17, 10 p., 48.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Therapeutic application of multipotent stem cells

    Mirzaei, H., Sahebkar, A., Sichani, L. S., Moridikia, A., Nazari, S., Sadri Nahand, J., salehi, H., Stenvang, Jan, Masoudifar, A., Mirzaei, H. R. & Jaafari, M. R., 2018, In: Journal of Cellular Physiology. 233, 4, p. 2815–2823

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    The utility of LNA in microRNA-based cancer diagnostics and therapeutics

    Stenvang, Jan, Silahtaroglu, Asli, Lindow, M., Elmen, J. & Kauppinen, S., 2008, In: Seminars in Cancer Biology. 18, 2, p. 89-102 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The therapeutic potential of MicroRNAs in cancer

    Thorsen, S. B., Obad, S., Jensen, N. F., Stenvang, Jan & Kauppinen, S., 2012, In: Cancer Journal. 18, 3, p. 275-284 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

    Hansen, S. N., Ehlers, Natasja Spring, Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, José, Ditzel, H. J., Brünner, N., Rasmussen, A. S., Stenvang, Jan & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer

    Lin, X., Stenvang, Jan, Rasmussen, M. H., Zhu, S., Jensen, N. F., Tarpgaard, L. S., Yang, G., Belling, K., Andersen, C. L., Li, J., Bolund, L. & Brünner, N., 2015, In: BMC Genomics. 16, 17 p., 404.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells

    Høeberg, M., Noer, Julie Boertmann, Vistesen, M. V., Bartels, Annette Snejbjerg, Bech, E. M., Nygård, S. B., Lademann, U., Stenvang, Jan, Liu, S., Fuglsang, Anja Thoe, Brünner, N. & Moreira, José, 2023, In: Molecular Oncology. 17, 8, p. 1595-1612

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

    Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

    Ambjørner, S. E. B., Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, Michael, Saaby, Lasse, Larsen, Birger Brodin, Rump, S., Weigt, H., Brünner, N. & Stenvang, Jan, 4 Mar 2020, In: Cells. 9, 3, 22 p., 613.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Targeting of microRNAs for therapeutics

    Stenvang, Jan, Lindow, M. & Kauppinen, S., 2008, In: Biochemical Society Transactions. 36, Pt 6, p. 1197-200 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Targeting anti-cancer drug resistance in gastro-intestinal cancer: Inhibition of the SRPK1 kinase and degradation of the ABCG2 drug efflux pump

    Ladekarl, M., Schou, J. H. V., Roest, N. L., Stenvang, Jan, Brunner, N. & Vestlev, P. M., Sep 2020, p. S503-S504. 2 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  17. Published

    TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas

    Grunnet, M., Calatayud, D., Schultz, N. A., Hasselby, Jane Preuss, Mau-Sørensen, M., Brünner, N. & Stenvang, Jan, 2015, In: Scandinavian Journal of Gastroenterology. 50, 4, p. 485-494 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression

    Bjerre, C. A., Jensen, L. V., Belling, K. C., Würtz, S. Ø., Yadav, R., Lademann, U. A., Rigina, O., Do, K. N., Ditzel, H. J., Lykkesfeldt, A. E., Wang, J., Nielsen, H. B., Brünner, N., Gupta, R., Rasmussen, A. S. & Stenvang, Jan, 2013, In: Tumor Biology. 34, 6, p. 3839-3851 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    TIMP-1 overexpression does not affect sensitivity to HER2-targeting drugs in the HER2-gene-amplified SK-BR-3 human breast cancer cell line

    Deng, X., Fogh, L., Lademann, U. A., Jensen, V., Stenvang, Jan, Yang, H., Brünner, N. & Rasmussen, A. S., 2013, In: Tumor Biology. 34, 2, p. 1161-1170 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells

    Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V. & 1 others, Stenvang, Jan, 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Synthesis of thiazole linked chalcones and their pyrimidine analogues as anticancer agents

    Kesari, C., Rama, K. R., Sedighi, K., Stenvang, Jan, Björkling, Fredrik, Kankala, S. & Thota, N., 2021, In: Synthetic Communications. 51, 9, p. 1406-1416 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Jepsen, J. S., Nielsen, C., Wengel, J. & Stenvang, Jan, 15 Feb 2005, In: Bioorganic & Medicinal Chemistry. 13, 4, p. 1249-60 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Synthesis and biological evaluation of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Stenvang, Jan & Wengel, J., 2005, In: Nucleosides, nucleotides & nucleic acids. 24, 5-7, p. 397-400 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Synthesis and biological evaluation of branched and conformationally restricted analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Andersen, N. K., Stenvang, Jan, Hansen, F. G., Haselmann, K. F., Nielsen, C. & Wengel, J., 1 Apr 2005, In: Bioorganic & Medicinal Chemistry. 13, 7, p. 2597-621 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    State of the art in microRNA as diagnostic and therapeutic biomarkers in chronic lymphocytic leukemia

    Mirzaei, H., Fathullahzadeh, S., Khanmohammadi, R., Darijani, M., Momeni, F., Masoudifar, A., Goodarzi, M., Mardanshah, O., Stenvang, Jan, Jaafari, M. R. & Mirzaei, H. R., Feb 2018, In: Journal of Cellular Physiology. 233, 2, p. 888-900 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

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