Jan Stenvang

Jan Stenvang

Associate Professor


  1. Published

    The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

    Ambjørner, Sophie Emilie Blomgren, Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, Michael, Saaby, Lasse, Larsen, Birger Brodin, Rump, S., Weigt, H., Brünner, Nils & Stenvang, Jan, 4 Mar 2020, In: Cells. 9, 3, 22 p., 613.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability

    Assarsson, E., Lundberg, M., Holmquist, G., Björkesten, J., Thorsen, S. B., Ekman, D., Eriksson, A., Rennel Dickens, E., Ohlsson, S., Edfeldt, G., Andersson, A., Lindstedt, P., Stenvang, Jan, Gullberg, M. & Fredriksson, S., 2014, In: PLOS ONE. 9, 4, 11 p., e95192.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers

    Bergmann, T. K., Stage, T. B., Stenvang, Jan, Christophersen, P., Jacobsen, T. A., Roest, N. L., Vestlev, P. M. & Brünner, Nils, 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 4, p. 329-337

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression

    Bjerre, C. A., Jensen, L. V., Belling, K. C., Würtz, S. Ø., Yadav, R., Lademann, U. A., Rigina, O., Do, K. N., Ditzel, H. J., Lykkesfeldt, A. E., Wang, J., Nielsen, H. B., Brünner, Nils, Gupta, R., Rasmussen, A. S. & Stenvang, Jan, 2013, In: Tumor Biology. 34, 6, p. 3839-3851 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue

    Karlsson, Camilla Cederbye, Palshof, J. A., Kuhlmann, Tine Plato, Duun-Henriksen, A. K., Linnemann, D., Stenvang, Jan, Nielsen, Dorte Lisbet, Brünner, Nils & Viuff, B. M., 3 Jun 2016, In: Scientific Reports. 6, 16 p., 26997.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Sequential versus combined treatment of human breast cancer cells with antiestrogens and the vitamin D analogue EB1089 and evaluation of predictive markers for vitamin D treatment.

    Christensen, G. L., Stenvang, Jan, Fog, C. K., Christensen, I. J. & Lykkesfeldt, A. E., 2004, In: Breast Cancer Research and Treatment. p. 53–63

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

    Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, Nils, Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    TIMP-1 overexpression does not affect sensitivity to HER2-targeting drugs in the HER2-gene-amplified SK-BR-3 human breast cancer cell line

    Deng, X., Fogh, L., Lademann, U. A., Jensen, V., Stenvang, Jan, Yang, H., Brünner, Nils & Rasmussen, A. S., 2013, In: Tumor Biology. 34, 2, p. 1161-1170 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Comprehensive genomic analysis of Oesophageal Squamous Cell Carcinoma reveals clinical relevance

    Du, P., Huang, P., Huang, X., Li, X., Feng, Z., Li, F., Liang, S., Song, Y., Stenvang, Jan, Brünner, Nils, Yang, H., Ou, Y., Gao, Q. & Li, L., Dec 2017, In: Scientific Reports. 7, 9 p., 15324.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment

    Ellegaard, A., Dehlendorff, C., Vind, Anna Constance, Anand, A., Kristiansen, Luise Cederkvist, Petersen, N. H. T., Nylandsted, J., Stenvang, Jan, Mellemgaard, A., Osterlind, K., Friis, S. & Jaattela, Marja, Jul 2016, In: EBioMedicine. 9, p. 130-139 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo

    Eskildsen, T., Taipaleenmäki, H., Stenvang, Jan, Abdallah, B., Ditzel, N., Nossent, A. Y., Bak, Mads, Kauppinen, S. & Kassem, M., 12 Apr 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 15, p. 6139-44 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Protein kinase C alpha is a marker for antiestrogen resistance and is involved in the growth of tamoxifen resistant human breast cancer cells

    Frankel, Lisa, Lykkesfeldt, A. E., Hansen, J. B. H. & Stenvang, Jan, 2007, In: Breast Cancer Research and Treatment. 104, 2, p. 165-179 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas

    Grunnet, M., Calatayud, D., Schultz, N. A., Hasselby, Jane Preuss, Mau-Sørensen, M., Brünner, Nils & Stenvang, Jan, 2015, In: Scandinavian Journal of Gastroenterology. 50, 4, p. 485-494 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Progesterone receptor isoform analysis by quantitative real-time polymerase chain reaction in formalin-fixed, paraffin-embedded canine mammary dysplasias and tumors

    Guil-Luna, S., Stenvang, Jan, Brünner, Nils, Sánchez-Céspedes, R., Millán, Y., Gómez-Laguna, J. & Mulas, J. M. D. L., 2014, In: Veterinary Pathology. 51, 5, p. 895-902 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma

    Guil-Luna, S., Stenvang, Jan, Brünner, Nils, De Andrés, F. J., Rollón, E., Domingo, V., Sánchez-Céspedes, R., Millán, Y. & Mulas, J. M. D. L., 2014, In: B M C Veterinary Research. 10, 8 p., 296.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Drug resistance in colorectal cancer cell lines is partially associated with aneuploidy status in light of profiling gene expression

    Guo, J., Xu, S., Huang, X., Li, L., Zhang, C., Pan, Q., Ren, Z., Zhou, R., Ren, Y., Zi, J., Wu, L., Stenvang, Jan, Brünner, Nils, Wen, B. & Liu, S., 2016, In: Journal of Proteome Research. 15, 11, p. 4047–4059 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

    Hansen, S. N., Ehlers, Natasja Spring, Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, José, Ditzel, H. J., Brünner, Nils, Rasmussen, A. S., Stenvang, Jan & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

    Hansen, S. N., Westergaard, David, Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, K. G., Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, José, Brünner, Nils, Stenvang, Jan & Rasmussen, A. S., 2015, In: Tumor Biology. 36, 6, p. 4327-4338 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells

    Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, José, Jensen, Lars Juhl, Gupta, R., Lademann, U. A., Brünner, Nils, Olsen, Jesper Velgaard & Stenvang, Jan, 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Synthesis and biological evaluation of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Stenvang, Jan & Wengel, J., 2005, In: Nucleosides, nucleotides & nucleic acids. 24, 5-7, p. 397-400 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Synthesis and biological evaluation of branched and conformationally restricted analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Andersen, N. K., Stenvang, Jan, Hansen, F. G., Haselmann, K. F., Nielsen, C. & Wengel, J., 1 Apr 2005, In: Bioorganic & Medicinal Chemistry. 13, 7, p. 2597-621 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)

    Hrdlicka, P. J., Jepsen, J. S., Nielsen, C., Wengel, J. & Stenvang, Jan, 15 Feb 2005, In: Bioorganic & Medicinal Chemistry. 13, 4, p. 1249-60 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    BMP-2 induces EMT and breast cancer stemness through Rb and CD44

    Huang, P., Chen, A., He, W., Li, Z., Zhang, G., Liu, Z., Liu, G., Liu, X., He, S., Xiao, G., Huang, F., Stenvang, Jan, Brünner, Nils, Hong, A. & Wang, J., 2017, In: Cell Death Discovery. 3, 12 p., 17039.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    lncRNA profile study reveals the mRNAs and lncRNAs associated with docetaxel resistance in breast cancer cells

    Huang, P., Li, F., Li, L., You, Y., Luo, S., Dong, Z., Gao, Q., Wu, S., Brünner, Nils & Stenvang, Jan, 1 Dec 2018, In: Scientific Reports. 8, 1, 17970.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A Comprehensive RNA Study to Identify circRNA and miRNA Biomarkers for Docetaxel Resistance in Breast Cancer

    Huang, P., Li, F., Mo, Z., Geng, C., Wen, F., Zhang, C., Guo, J., Wu, S., Li, L., Brünner, Nils & Stenvang, Jan, 2021, In: Frontiers in Oncology. 11, 14 p., 669270.

    Research output: Contribution to journalJournal articleResearchpeer-review

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