Jan Christiansen

Jan Christiansen

Associate Professor


  1. 2020
  2. Published

    Cytoplasmic mRNPs revisited: Singletons and condensates

    Mateu-Regue, A., Nielsen, Finn Cilius & Christiansen, Jan, 2020, In: BioEssays. 42, 12, 13 p., 2000097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. Published

    Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons

    Mateu-Regué, À., Christiansen, Jan, Bagger, F. O., Winther, O., Hellriegel, C. & Nielsen, Finn Cilius, 2019, In: Cell Reports. 29, 3, p. 736-748, e1-e4

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2016
  6. Published

    Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes

    Gorbatenko, A., Olesen, C. W., Loebl, N., Sigurdsson, H. H., Bianchi, C., Pedraz Cuesta, E., Christiansen, Jan & Pedersen, Stine Helene Falsig, 2016, In: Biochemical Journal. 473, 21, p. 4027-4044 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    RNA assemblages orchestrate complex cellular processes

    Nielsen, Finn Cilius, Hansen, H. T. & Christiansen, Jan, 2016, In: BioEssays. 38, 7, p. 674-681 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2015
  9. Published

    Drosophila Imp iCLIP identifies an RNA assemblage coordinating F-actin formation

    Hansen, H. T., Rasmussen, S. H., Adolph, S. K., Plass, M., Krogh, Anders, Sanford, J., Nielsen, Finn Cilius & Christiansen, Jan, 2015, In: Genome Biology (Online Edition). 16, 16 p., 123.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2014
  11. Published

    IMP3 RNP safe houses prevent miRNA-directed HMGA2 mRNA decay in cancer and development

    Jønson, L., Christiansen, Jan, Hansen, T. V. O., Vikeså, J., Yamamoto, Y. & Nielsen, Finn Cilius, 2014, In: Cell Reports. 7, 2, p. 539-551 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2013
  13. Published

    mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts.

    Dai, N., Christiansen, Jan, Nielsen, F. & Avruch, J., 2013, In: Genes & Development. 27, 3, p. 301-312 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2011
  15. Published

    Isolation of RNP granules

    Jønson, L., Nielsen, Finn Cilius & Christiansen, Jan, 2011, RNA: methods and protocols. Nielsen, H. (ed.). Springer, Vol. 703. p. 265-273 9 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    The post-transcriptional operon

    Tenenbaum, S. A., Christiansen, Jan & Nielsen, Henrik, 2011, RNA: methods and protocols. Nielsen, H. (ed.). Springer, p. 237-245 9 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. 2009
  18. Published

    CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties

    Lillestøl, R. K., Shah, S. A., Brügger, K., Redder, P., Phan, Safir Hien, Christiansen, Jan & Garrett, Roger Antony, 2009, In: Molecular Microbiology. 72, 1, p. 259-272

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2008
  20. Published

    Embryonic expression of Drosophila IMP in the developing CNS and PNS

    Adolph, S. K., Delotto, R., Nielsen, Finn Cilius & Christiansen, Jan, 2008, In: Gene Expression Patterns. 9, 3, p. 138-143 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2007
  22. Published

    Molecular composition of IMP1 ribonucleoprotein granules.

    Jønson, L., Vikesaa, J., Krogh, Anders, Nielsen, Lars Kamp, Hansen, T. V., Borup, R., Johnsen, A. H., Christiansen, Jan & Nielsen, Finn Cilius, 2007, In: Molecular and Cellular Proteomics. 6, 5, p. 798-811 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2006
  24. Published

    RNA-binding IMPs promote cell adhesion and invadopodia formation.

    Vikesaa, J., Hansen, T. V. O., Jønson, L., Borup, R., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2006, In: EMBO Journal. 25, 7, p. 1456-68 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2005
  26. Published

    Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer

    Hammer, N. A., Hansen, T. V. O., Byskov, A. G., Rajpert-De Meyts, E., Grøndahl, M. L., Bredkjaer, H. E., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2005, In: Reproduction. 130, 2, p. 203-12 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2004
  28. Published

    Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice

    Hansen, T. V. O., Hammer, N. A., Nielsen, J., Madsen, Mette, Dalbaeck, C., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability

    Nielsen, J., Kristensen, M. A., Willemoës, Martin, Nielsen, F. C. & Christiansen, Jan, 2004, In: Nucleic Acids Research. 32, 14, p. 4368-4376

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2003
  31. Published

    Nuclear transit of human zipcode-binding protein IMP1

    Nielsen, J., Adolph, S., Rajpert-De Meyts, E., Lykke-Andersen, J., Koch, G., Christiansen, Jan & Nielsen, F., 2003, In: Biochemical Journal. vol 376, p. 383-391

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2002
  33. Published

    Cytoplasmic trafficking of IGF-II mRNA-binding rotein by conserved KH domains

    Nielsen, Finn Cilius, Nielsen, J., Koch, G. & Christiansen, Jan, 2002, In: Journal of Cell Science. 115, p. 2087-2097

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Human insulin-like growth II leader 2 mediates internal initiation of translation

    Pedersen, S., Christiansen, Jan, Hansen, T., Larsen, M. & Nielsen, F., 2002, In: Biochem. J.. 363, p. 37-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Human insulin-like growth factor II leader 2 mediates internal initiation of translation

    Pedersen, S., Christiansen, Jan, Hansen, T. O., Larsen, M. & Nielsen, Finn Cilius, 2002, In: Biochem. J.. 363, p. 37-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2001
  37. Published

    c-myc and IGF-II mRNA-binding protein (CRD-BP/IMP-1) in benign and malignant mesenchymal tumors

    Ioanidis, P., Trangas, T., Dimitriadis, E., Samiotaki, M., Kyriazoglou, I., Tsiapalis, C. M., Kittas, C., Agnantis, N., Nielsen, Finn Cilius, Nielsen, J., Christiansen, Jan & Pandis, N., 2001, In: International Journal of Cancer. 94, p. 480-484

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis

    Lu, M., Nakamura, R. M., Dent, E. D., Zhang, J., Nielsen, Finn Cilius, Christiansen, Jan, Chan, E. K. L. & Tan, E. M., 2001, In: American Journal of Pathology. 159, p. 945-953

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2000
  40. Published

    H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein

    Runge, S., Nielsen, Finn Cilius, Nielsen, J., Andersen, J. L., Wewer, Ulla M. & Christiansen, Jan, 2000, In: Journal of Biological Chemistry. 275, 38, p. 29562-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The biphasic expression of IMP/Vg1-RBP is conserved between vertebrates and Drosophila

    Nielsen, J., Nielsen, Finn Cilius, Jakobsen, R. K. & Christiansen, Jan, 2000, In: Mechanisms of Development. 96, p. 129-132

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 1999
  43. Published

    A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development

    Nielsen, J., Christiansen, Jan, Lykke-Andersen, J., Johnsen, A. H., Wewer, Ulla M. & Nielsen, Finn Cilius, 1999, In: Molecular and Cellular Biology. 19, 2, p. 1262-1270 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 1998
  45. Published

    Analysis of RNA-Protein Complexes in vitro

    Kjems, J., Egebjerg, J. & Christiansen, Jan, 1998, Amsterdam: Elsevier. 252 p.

    Research output: Book/ReportBookResearch

  46. Published

    The C-terminal carboxy group of T7 RNA polymerase ensures efficient magnesium ion-dependent catalysis

    Lykke-Andersen, J. & Christiansen, Jan, 1998, In: Nucleic Acids Research. Vol. 26, no. 24, p. 5630-5635

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 1997
  48. Published

    Distinct repression of translation by wortmannin and rapamycin

    Pedersen, S., Celis, J. E., Nielsen, J., Christiansen, Jan & Nielsen, Finn Cilius, 1997, In: European Journal of Biochemistry. 247, p. 449-456

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 1995
  50. Published

    Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway

    Nielsen, Finn Cilius, Østergaard, L., Nielsen, J. & Christiansen, Jan, 1995, In: Nature. Vol 377, p. 358-362

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 1994
  52. Published

    A guanosine quadruplex and two stable hairpins flank a major cleavage site in insulin-like growth factor II mRNA

    Christiansen, Jan, Kofod, M. & Nielsen, F. C., 1994, In: Nucleic Acids Research. 22, 25, p. 5709-16 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Insulin-like growth factor II mRNA, peptides, and receptors in a thoracopulmonary malignant small round cell tumor

    Nielsen, F. C., Orskov, C., Haselbacher, G., Ramlau, J., Christiansen, Jan, Schmiegelow, Kjeld & Rehfeld, Jens Frederik, 1994, In: Cancer. 73, 4, p. 1312-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 1993
  55. Published

    Biosynthesis of 10 kDa and 7.5 kDa insulin-like growth factor II in a human rhabdomyosarcoma cell line

    Nielsen, F. C., Haselbacher, G., Christiansen, Jan, Lake, M., Gammeltoft, S. & Grønborg, M., 1993, In: Molecular and Cellular Endocrinology. 93, 1, p. 87-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 1992
  57. Published

    Endonucleolysis in the turnover of insulin-like growth factor II mRNA

    Nielsen, F. C. & Christiansen, Jan, 1992, In: Journal of Biological Chemistry. 267, 27, p. 19404-11 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 1991
  59. Published

    Attachment sites of primary binding proteins L1, L2 and L23 on 23 S ribosomal RNA of Escherichia coli

    Egebjerg, J., Christiansen, Jan & Garrett, Roger Antony, 1991, In: Journal of Molecular Biology. 222, 2, p. 251-264

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Insulin-like growth factor II: complexity of biosynthesis and receptor binding

    Gammeltoft, S., Christiansen, Jan, Nielsen, F. C. & Verland, S., 1991, In: Advances in Experimental Medicine and Biology. 293, p. 31-44 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4045