Jan Christiansen
Associate Professor emeritus
Computational and RNA Biology
Ole Maaløes Vej 5
2200 København N.
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Drosophila Imp iCLIP identifies an RNA assemblage coordinating F-actin formation
Hansen, H. T., Rasmussen, S. H., Adolph, S. K., Plass, M., Krogh, Anders, Sanford, J., Nielsen, Finn Cilius & Christiansen, Jan, 2015, In: Genome Biology (Online Edition). 16, 16 p., 123.Research output: Contribution to journal › Journal article › Research › peer-review
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c-myc and IGF-II mRNA-binding protein (CRD-BP/IMP-1) in benign and malignant mesenchymal tumors
Ioanidis, P., Trangas, T., Dimitriadis, E., Samiotaki, M., Kyriazoglou, I., Tsiapalis, C. M., Kittas, C., Agnantis, N., Nielsen, Finn Cilius, Nielsen, J., Christiansen, Jan & Pandis, N., 2001, In: International Journal of Cancer. 94, p. 480-484Research output: Contribution to journal › Journal article › Research › peer-review
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A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development
Nielsen, J., Christiansen, Jan, Lykke-Andersen, J., Johnsen, A. H., Wewer, Ulla M. & Nielsen, Finn Cilius, 1999, In: Molecular and Cellular Biology. 19, 2, p. 1262-1270 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A guanosine quadruplex and two stable hairpins flank a major cleavage site in insulin-like growth factor II mRNA
Christiansen, Jan, Kofod, M. & Nielsen, F. C., 1994, In: Nucleic Acids Research. 22, 25, p. 5709-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis
Lu, M., Nakamura, R. M., Dent, E. D., Zhang, J., Nielsen, Finn Cilius, Christiansen, Jan, Chan, E. K. L. & Tan, E. M., 2001, In: American Journal of Pathology. 159, p. 945-953Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of RNA-Protein Complexes in vitro
Kjems, J., Egebjerg, J. & Christiansen, Jan, 1998, Amsterdam: Elsevier. 252 p.Research output: Book/Report › Book › Research
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Attachment sites of primary binding proteins L1, L2 and L23 on 23 S ribosomal RNA of Escherichia coli
Egebjerg, J., Christiansen, Jan & Garrett, Roger Antony, 1991, In: Journal of Molecular Biology. 222, 2, p. 251-264Research output: Contribution to journal › Journal article › Research › peer-review
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Biosynthesis of 10 kDa and 7.5 kDa insulin-like growth factor II in a human rhabdomyosarcoma cell line
Nielsen, F. C., Haselbacher, G., Christiansen, Jan, Lake, M., Gammeltoft, S. & Grønborg, M., 1993, In: Molecular and Cellular Endocrinology. 93, 1, p. 87-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties
Lillestøl, R. K., Shah, S. A., Brügger, K., Redder, P., Phan, Safir Hien, Christiansen, Jan & Garrett, Roger Antony, 2009, In: Molecular Microbiology. 72, 1, p. 259-272Research output: Contribution to journal › Journal article › Research › peer-review
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Cytoplasmic mRNPs revisited: Singletons and condensates
Mateu-Regue, A., Nielsen, Finn Cilius & Christiansen, Jan, 2020, In: BioEssays. 42, 12, 13 p., 2000097.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytoplasmic trafficking of IGF-II mRNA-binding rotein by conserved KH domains
Nielsen, Finn Cilius, Nielsen, J., Koch, G. & Christiansen, Jan, 2002, In: Journal of Cell Science. 115, p. 2087-2097Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct repression of translation by wortmannin and rapamycin
Pedersen, S., Celis, J. E., Nielsen, J., Christiansen, Jan & Nielsen, Finn Cilius, 1997, In: European Journal of Biochemistry. 247, p. 449-456Research output: Contribution to journal › Journal article › Research › peer-review
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Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice
Hansen, Thomas van Overeem, Hammer, N. A., Nielsen, J., Madsen, Mette, Dalbaeck, C., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Embryonic expression of Drosophila IMP in the developing CNS and PNS
Adolph, S. K., Delotto, R., Nielsen, Finn Cilius & Christiansen, Jan, 2008, In: Gene Expression Patterns. 9, 3, p. 138-143 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endonucleolysis in the turnover of insulin-like growth factor II mRNA
Nielsen, F. C. & Christiansen, Jan, 1992, In: Journal of Biological Chemistry. 267, 27, p. 19404-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer
Hammer, N. A., Hansen, Thomas van Overeem, Byskov, A. G., Rajpert-De Meyts, E., Grøndahl, M. L., Bredkjaer, H. E., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2005, In: Reproduction. 130, 2, p. 203-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway
Nielsen, Finn Cilius, Østergaard, L., Nielsen, J. & Christiansen, Jan, 1995, In: Nature. Vol 377, p. 358-362Research output: Contribution to journal › Journal article › Research › peer-review
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H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein
Runge, S., Nielsen, Finn Cilius, Nielsen, J., Andersen, J. L., Wewer, Ulla M. & Christiansen, Jan, 2000, In: Journal of Biological Chemistry. 275, 38, p. 29562-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human insulin-like growth II leader 2 mediates internal initiation of translation
Pedersen, S., Christiansen, Jan, Hansen, T., Larsen, M. & Nielsen, F., 2002, In: Biochem. J.. 363, p. 37-44Research output: Contribution to journal › Journal article › Research › peer-review
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Human insulin-like growth factor II leader 2 mediates internal initiation of translation
Pedersen, S., Christiansen, Jan, Hansen, T. O., Larsen, M. & Nielsen, Finn Cilius, 2002, In: Biochem. J.. 363, p. 37-44Research output: Contribution to journal › Journal article › Research › peer-review
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IMP3 RNP safe houses prevent miRNA-directed HMGA2 mRNA decay in cancer and development
Jønson, L., Christiansen, Jan, Hansen, Thomas van Overeem, Vikeså, J., Yamamoto, Y. & Nielsen, Finn Cilius, 2014, In: Cell Reports. 7, 2, p. 539-551 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin-like growth factor II mRNA, peptides, and receptors in a thoracopulmonary malignant small round cell tumor
Nielsen, F. C., Orskov, C., Haselbacher, G., Ramlau, J., Christiansen, Jan, Schmiegelow, Kjeld & Rehfeld, Jens Frederik, 1994, In: Cancer. 73, 4, p. 1312-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin-like growth factor II: complexity of biosynthesis and receptor binding
Gammeltoft, S., Christiansen, Jan, Nielsen, F. C. & Verland, S., 1991, In: Advances in Experimental Medicine and Biology. 293, p. 31-44 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation of RNP granules
Jønson, L., Nielsen, Finn Cilius & Christiansen, Jan, 2011, RNA: methods and protocols. Nielsen, H. (ed.). Springer, Vol. 703. p. 265-273 9 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Molecular composition of IMP1 ribonucleoprotein granules.
Jønson, L., Vikesaa, J., Krogh, Anders, Nielsen, Lars Kamp, Hansen, T. V., Borup, R., Johnsen, A. H., Christiansen, Jan & Nielsen, Finn Cilius, 2007, In: Molecular and Cellular Proteomics. 6, 5, p. 798-811 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nuclear transit of human zipcode-binding protein IMP1
Nielsen, J., Adolph, S., Rajpert-De Meyts, E., Lykke-Andersen, J., Koch, G., Christiansen, Jan & Nielsen, F., 2003, In: Biochemical Journal. vol 376, p. 383-391Research output: Contribution to journal › Journal article › Research › peer-review
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Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes
Gorbatenko, A., Olesen, C. W., Loebl, N., Sigurdsson, H. H., Bianchi, C., Pedraz Cuesta, E., Christiansen, Jan & Pedersen, Stine Helene Falsig, 2016, In: Biochemical Journal. 473, 21, p. 4027-4044 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RNA assemblages orchestrate complex cellular processes
Nielsen, Finn Cilius, Hansen, H. T. & Christiansen, Jan, 2016, In: BioEssays. 38, 7, p. 674-681 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RNA-binding IMPs promote cell adhesion and invadopodia formation.
Vikesaa, J., Hansen, T. V. O., Jønson, L., Borup, R., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2006, In: EMBO Journal. 25, 7, p. 1456-68 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability
Nielsen, J., Kristensen, M. A., Willemoës, Martin, Nielsen, F. C. & Christiansen, Jan, 2004, In: Nucleic Acids Research. 32, 14, p. 4368-4376Research output: Contribution to journal › Journal article › Research › peer-review
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Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons
Mateu-Regué, À., Christiansen, Jan, Bagger, F. O., Winther, O., Hellriegel, C. & Nielsen, Finn Cilius, 2019, In: Cell Reports. 29, 3, p. 736-748, e1-e4Research output: Contribution to journal › Journal article › Research › peer-review
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The C-terminal carboxy group of T7 RNA polymerase ensures efficient magnesium ion-dependent catalysis
Lykke-Andersen, J. & Christiansen, Jan, 1998, In: Nucleic Acids Research. Vol. 26, no. 24, p. 5630-5635Research output: Contribution to journal › Journal article › Research › peer-review
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The biphasic expression of IMP/Vg1-RBP is conserved between vertebrates and Drosophila
Nielsen, J., Nielsen, Finn Cilius, Jakobsen, R. K. & Christiansen, Jan, 2000, In: Mechanisms of Development. 96, p. 129-132Research output: Contribution to journal › Journal article › Research › peer-review
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The post-transcriptional operon
Tenenbaum, S. A., Christiansen, Jan & Nielsen, Henrik, 2011, RNA: methods and protocols. Nielsen, H. (ed.). Springer, p. 237-245 9 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Unveiling mRNP composition by fluorescence correlation and cross-correlation spectroscopy using cell lysates
Mateu-Regué, À., Christiansen, Jan, Bagger, F. O., Hellriegel, C. & Nielsen, Finn Cilius, 2021, In: Nucleic Acids Research. 49, 20, 15 p., e119.Research output: Contribution to journal › Journal article › Research › peer-review
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mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts.
Dai, N., Christiansen, Jan, Nielsen, F. & Avruch, J., 2013, In: Genes & Development. 27, 3, p. 301-312 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4045
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IMP3 RNP safe houses prevent miRNA-directed HMGA2 mRNA decay in cancer and development
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
240
downloads
RNA assemblages orchestrate complex cellular processes
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
180
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Drosophila Imp iCLIP identifies an RNA assemblage coordinating F-actin formation
Research output: Contribution to journal › Journal article › Research › peer-review
Published