Inge Marie Svane

Clinical Professor

Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
- inge.marie.svane@regionh.dk
- https://ikm.ku.dk/
Phone: +4538683868

Member of:

Clinical Oncology

ORCID: 0000-0002-9451-6037

Publication year:

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2024
Published
Reduced mitochondrial respiration in peripheral T cells after paediatric heamatopoietic stem cell transplantation
Mølgaard, K., Kielsen, K., Ifversen, M., Met, Özcan, Svane, Inge Marie & Muller, Klaus, 2024, In: Frontiers in Immunology. 14, 1327977.
Research output: Contribution to journal › Journal article › Research › peer-review
2023
Published
Editorial: safety and efficacy of infliximab and corticosteroids in checkpoint inhibitor-induced colitis—authors' reply
Dahl, E. K., Abed, O. K., Kjeldsen, J., dqp123, dqp123, Svane, Inge Marie, Dige, A., Agnholt, J. S., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, Jan 2023, In: Alimentary Pharmacology and Therapeutics. 57, 1, p. 152-153 2 p.
Research output: Contribution to journal › Editorial › Research › peer-review
Published
of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes
Hulen, T. M., Friese, C., Kristensen, N. P., Granhøj, J. S., Borch, T. H., Peeters, M. J. W., Donia, M., Andersen, Mads Hald, Hadrup, S. R., Svane, Inge Marie & Met, Özcan, 2023, In: Frontiers in Immunology. 14, 15 p., 1180997.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
ASO Visual Abstract: Earlier Recurrence Detection Using Routine FDG PET-CT Scans in Surveillance of Stage IIB to IIID Melanoma-A National Cohort Study of 1480 Patients
Helvind, N. M., Weitemeyer, M. B. M., Chakera, A. H., Hendel, Helle Westergren, Ellebæk, E., Svane, Inge Marie, Kjærskov, M. W., Bojesen, S., Skyum, H., Petersen, S. K., Bastholt, L., Johansen, Christoffer, Bidstrup, P. E. & Hølmich, Lisbet Rosenkrantz, 2023, In: Annals of Surgical Oncology. 30, 4, p. 2389-2390 2 p.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
An arginase1- and PD-L1-derived peptide-based vaccine for myeloproliferative neoplasms: A first-in-man clinical trial
Grauslund, J. H., Holmström, M. O., Martinenaite, E., Lisle, T. L., Glöckner, H. J., Fassi, Daniel El , Klausen, U., Mortensen, R. E. J., Jørgensen, N., Kjær, L., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1117466.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Combination therapy with immune check point inhibitors and acute kidney injury
Valentin, A., Møller, A. K. H., Palshof, J. A., Broberg, B., Gravesen, E., Svane, Inge Marie & Hansen, Ditte, 2023, In: Acta Oncologica. 62, 2, p. 121-125 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, Anders Handrup, Østergaard, Ole, Emdal, Kristina Bennet, Svane, Inge Marie & Olsen, Jesper Velgaard, 2023, In: Proteomics. 23, 7-8, 2200039.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Earlier Recurrence Detection Using Routine FDG PET-CT Scans in Surveillance of Stage IIB to IIID Melanoma: A National Cohort Study of 1480 Patients
Helvind, N. M., Weitemeyer, M. B. M., Chakera, A. H., Hendel, Helle Westergren, Ellebæk, E., Svane, Inge Marie, Kjærskov, M. W., Bojesen, S., Skyum, H., Petersen, S. K., Bastholt, L., Johansen, Christoffer, Bidstrup, P. E. & Hølmich, Lisbet Rosenkrantz, 2023, In: Annals of Surgical Oncology. 30, 4, p. 2377-2388 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
First in man study: Bcl-Xl_42-CAF^®09b vaccines in patients with locally advanced prostate cancer
Mørk, S. K., Kongsted, P., Westergaard, M. C. W., Albieri, B., Granhøj, J. S., Donia, M., Martinenaite, E., Holmström, M. O., Madsen, K., Kverneland, A. H., Kjeldsen, J. W., Holmstroem, R. B., Lorentzen, C. L., Nørgaard, N., Andreasen, L. V., Wood, G. K., Christensen, D., Klausen, M. S., Hadrup, S. R., thor Straten, P. & 2 others, Andersen, Mads Hald & Svane, Inge Marie, 2023, In: Frontiers in Immunology. 14, 1122977.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Intratumoral T-cell and B-cell receptor architecture associates with distinct immune tumor microenvironment features and clinical outcomes of anti-PD-1/L1 immunotherapy
Schina, A., Sztupinszki, Z., Svane, Inge Marie, Szallasi, Z., Jönsson, G. & Donia, M., 2023, In: Journal for ImmunoTherapy of Cancer. 11, 8, 12 p., 006941.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Letter: be careful of gastrointestinal CMV infection in adverse event from ICIs therapy in solid tumours — Authors' reply
Dahl, E., Abed, O., Agnholt, J., Bjerrum, Jakob Tveiten , Dige, A., Kjeldsen, J., Svane, Inge Marie, Donia, M. & Seidelin, Jakob Benedict, 2023, In: Alimentary Pharmacology and Therapeutics. 57, 8, p. 918-919
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
Long-term follow-up of anti-PD-1 naïve patients with metastatic melanoma treated with IDO/PD-L1 targeting peptide vaccine and nivolumab
Lorentzen, C. L., Kjeldsen, J. W., Ehrnrooth, E., Andersen, M. H. & Svane, Inge Marie, 2023, In: Journal for ImmunoTherapy of Cancer. 11, 5, 10 p., e006755.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy
Borch, A., Bjerregaard, A. M., Araujo Barbosa de Lima, V., Østrup, O., Yde, C. W., Eklund, A. C., Mau-Sørensen, M., Barra, C., Svane, Inge Marie, Nielsen, Finn Cilius, Funt, S. A., Lassen, Ulrik Niels & Hadrup, S. R., 2023, In: Frontiers in Genetics. 14, 13 p., 1058605.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Phase 2 study of ipilimumab, nivolumab, and tocilizumab combined with stereotactic body radiotherapy in patients with refractory pancreatic cancer (TRIPLE-R)
Chen, I. M., Donia, M., Chamberlain, C. A., Jensen, Agnete Witness Præst, Draghi, A., Theile, S., Madsen, K., Hasselby, Jane Preuss, Toxværd, A., Høgdall, Estrid Vilma Solyom, Lorentzen, T., Wilken, E. E., Geertsen, P., Svane, Inge Marie, Johansen, Julia Sidenius & Nielsen, D., 2023, In: European Journal of Cancer. 180, p. 125-133 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy
Mortensen, R. E. J., Holmström, M. O., Lisle, T. L., Hasselby, Jane Preuss, Willemoe, G. L., Met, Özcan, Svane, Inge Marie, Johansen, Julia Sidenius, Nielsen, Dorte Lisbet, Chen, I. M. & Andersen, Mads Hald, 2023, In: Journal for ImmunoTherapy of Cancer. 11, 3
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Quality of life and mental health in real-world patients with resected stage III/IV melanoma receiving adjuvant immunotherapy
Pedersen, S., Holmstroem, R. B., von Heymann, A., Tolstrup, L. K., Madsen, K., Petersen, M. A., Haslund, C. A., Ruhlmann, C. H., Schmidt, H., Johansen, Christoffer, Svane, Inge Marie & Ellebaek, E., 2023, In: Acta Oncologica. 62, 1, p. 62-69 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Randomised phase II trial of stereotactic body radiotherapy in combination with checkpoint inhibitors in metastatic castration-resistant prostate cancer (CheckPRO): a study protocol
Spindler, N. J., Persson, Gitte F., Theile, S., Nielsen, D. L., Høgdall, Estrid Vilma Solyom, Al-Farra, G., Hendel, Helle Westergren, Lorentzen, T., Svane, Inge Marie, Lindberg, H. & Eefsen, R. L., 2023, In: BMJ Open. 13, 1, 8 p., e063500.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Restoring tumor immunogenicity with dendritic cell reprogramming
Zimmermannova, O., Ferreira, A. G., Ascic, E., Santiago, M. V., Kurochkin, I., Hansen, M., Met, Ö., Caiado, I., Shapiro, I. E., Michaux, J., Humbert, M., Soto-Cabrera, D., Benonisson, H., Silvério-Alves, R., Gomez-Jimenez, D., Bernardo, C., Bauden, M., Andersson, R., Höglund, M., Miharada, K. & 9 others, Nakamura, Y., Hugues, S., Greiff, L., Lindstedt, M., Rosa, F. F., Pires, C. F., Bassani-Sternberg, M., Svane, Inge Marie & Pereira, C. F., 2023, In: Science immunology. 8, 85, 20 p., eadd4817.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Seasonal variation in effect of anti-PD-1 initiation on overall survival among patients with advanced melanoma
Ellebaek, E., Schina, A., Schmidt, H., Haslund, C. A., Bastholt, L., Svane, Inge Marie & dqp123, dqp123, 2023, In: Pigment Cell and Melanoma Research. 36, 2, p. 224-231
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Supervised clustering of peripheral immune cells associated with clinical response to checkpoint inhibitor therapy in patients with advanced melanoma
Kverneland, Anders Handrup, Thorsen, S. U., Granhøj, J. S., Hansen, F. S., Konge, M., Ellebæk, E., Donia, M. & Svane, Inge Marie, 2023, In: Immuno-Oncology and Technology. 20, 10 p., 100396.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy
Tvingsholm, S. A., Frej, M. S., Rafa, V. M., Hansen, U. K., Ormhøj, M., Tyron, A., Jensen, A. W. P., Kadivar, M., Bentzen, A. K., Munk, K. K., Aasbjerg, G. N., Ternander, J. S. H., Heeke, C., Tamhane, T., Schmess, C., Funt, S. A., Kjeldsen, J. W., Kverneland, A. H., Met, Ö., Draghi, A. & 4 others, Jakobsen, S. N., Donia, M., Svane, Inge Marie & Hadrup, S. R., 2023, In: Journal for ImmunoTherapy of Cancer. 11, 8, 16 p., e006847.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
TIL Therapy: Facts and Hopes
Monberg, Tine Juul, Borch, T. H., Svane, Inge Marie & Donia, M., 2023, In: Clinical Cancer Research. 29, 17, p. 3275-3283 9 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
Dolton, G., Rius, C., Wall, A., Szomolay, B., Bianchi, V., Galloway, S. A. E., Hasan, M. S., Morin, T., Caillaud, M. E., Thomas, H. L., Theaker, S., Tan, L. R., Fuller, A., Topley, K., Legut, M., Attaf, M., Hopkins, J. R., Behiry, E., Zabkiewicz, J., Alvares, C. & 13 others, Lloyd, A., Rogers, A., Henley, P., Fegan, C., Ottmann, O., Man, S., Crowther, M. D., Donia, M., Svane, Inge Marie, Cole, D. K., Brown, P. E., Rizkallah, P. & Sewell, A. K., 2023, In: Cell. 186, 16, p. 3333-3349.e27 45 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Accepted/In press
“One more chance to survive”: the experiences of patients with advanced melanoma and their partners with tumor-infiltrating lymphocyte therapy—a qualitative study and recommendations for future care
Egeler, M. D., Boomstra, E., Rohaan, M. W., Van den Heuvel, N. M. J., Fraterman, I., Delfos, M., van de Poll-Franse, L. V., Borch, T. H., Svane, Inge Marie, Haanen, J. B. A. G., Retèl, V. P. & Boekhout, A. H., 2023, (Accepted/In press) In: Journal of Cancer Survivorship.
Research output: Contribution to journal › Journal article › Research › peer-review
2022
Published
Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma
Mork, S. K., Kadivar, M., Bol, K. F., Draghi, A., Westergaard, M. C. W., Skadborg, S. K., Overgaard, N., Sorensen, A. B., Rasmussen, I. S., Andreasen, L. V., Yde, C. W., Trolle, T., Garde, C., Friis-Nielsen, J., Norgaard, N., Christensen, D., Kringelum, J. V., dqp123, dqp123, Hadrup, S. R. & Svane, Inge Marie, 31 Dec 2022, In: OncoImmunology. 11, 1, 15 p., 2023255.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immune checkpoint inhibitor treatment and ophthalmologist consultations in patients with malignant melanoma or lung cancer—A nationwide cohort study
D’Souza, M., Bagger, M., Alberti, M., Malmborg, M., Schou, Morten, Torp-Pedersen, Christian, Gislason, Gunnar Hilmar, Svane, Inge Marie & Kiilgaard, Jens Folke, 1 Jan 2022, In: Cancers. 14, 1, 13 p., 49.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV
Klausen, U., Grauslund, J. H., Jørgensen, N. G. D., Ahmad, S. M., Jonassen, M., Weis-Banke, S. E., Martinenaite, E., Pedersen, L. B., Lisle, T. L., Gang, Anne Ortved, Enggaard, L., Hansen, M., Holmström, M. O., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2022, In: Frontiers in Oncology. 12, 1023015.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Arginase-1 targeting peptide vaccine in patients with metastatic solid tumors – A phase I trial
Lorentzen, C. L., Martinenaite, E., Kjeldsen, J. W., Holmstroem, R. B., Mørk, S. K., Pedersen, A. W., Ehrnrooth, E., Andersen, Mads Hald & Svane, Inge Marie, 2022, In: Frontiers in Immunology. 13, 1023023.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells
Weis-Banke, S. E., Lisle, T. L., Perez Penco, Maria, Schina, A., Hübbe, M. L., Siersbæk, M., Holmström, M. O., Jørgensen, M. A., Svane, Inge Marie, Met, Özcan, Ødum, Niels, Madsen, Daniel Hargbøl, dqp123, dqp123, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 10, e005326.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
B Cells and Tertiary Lymphoid Structures: Friends or Foes in Cancer Immunotherapy?
Lauss, M., dqp123, dqp123, Svane, Inge Marie & Jönsson, G., 2022, In: Clinical Cancer Research. 28, 9, p. 1751–1758 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis
Holmstroem, R. B., Nielsen, Ole Haagen, Jacobsen, Søren, Riis, Lene Buhl, Theile, S., Bjerrum, Jakob Tveiten , Vilmann, Peter, Johansen, Julia Sidenius, Boisen, M. K., Eefsen, R. H. L., Svane, Inge Marie, Nielsen, Dorte Lisbet & Chen, I. M., 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cardiotoxicity in metastatic melanoma patients treated with BRAF and MEK inhibitors in a real-world setting
Pedersen, S., Larsen, K. O., Christensen, Alex Hørby, Svane, Inge Marie, Zerahn, B. & Ellebaek, E., 2022, In: Acta Oncologica. 61, 1, p. 45-51
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Clinical advances and ongoing trials on mRNA vaccines for cancer treatment
Lorentzen, C. L., Haanen, J. B., Met, Özcan & Svane, Inge Marie, 2022, In: The Lancet Oncology. 23, 10, p. e450-e458
Research output: Contribution to journal › Review › Research › peer-review
Published
Clinical value of routine [18F]2-fluoro-2-deoxy-d-glucose positron emission tomography scans as a decision tool for early immunotherapy discontinuation in advanced melanoma
Ellebaek, E., Schina, A., Andersen, R., Hendel, Helle Westergren, Svane, Inge Marie & dqp123, dqp123, 2022, In: International Journal of Cancer. 150, 11, p. 1870-1878 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Coexisting Alterations of MHC Class I Antigen Presentation and IFNg Signaling Mediate Acquired Resistance of Melanoma to Post-PD-1 Immunotherapy
Nielsen, M., Presti, M., Sztupinszki, Z., Jensen, Agnete Witness Præst, Draghi, A., Chamberlain, C. A., Schina, A., Yde, C. W., Wojcik, J., Szallasi, Z., Crowther, M. D., Svane, Inge Marie & Donia, M., 2022, In: Cancer Immunology Research. 10, 10, p. 1254-1262 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Epigenetic therapy in combination with a multi-epitope cancer vaccine targeting shared tumor antigens for high-risk myelodysplastic syndrome - a phase I clinical trial
Holmberg-Thydén, S., Dufva, I. H., Gang, Anne Ortved, Breinholt, M. F., Schejbel, L., Andersen, M. K., Kadivar, M., Svane, Inge Marie, Grønbæk, Kirsten, Hadrup, S. R. & El Fassi, D., 2022, In: Cancer Immunology, Immunotherapy. 71, p. 433-444
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Feasibility of Intratumoral Anti-PD1 as Treatment of Human Basal Cell Carcinoma: An Explorative Study with Adjuvant Ablative Fractional Laser
Omland, S. H., Ejlertsen, J. S., Krustrup, D., Christensen, R. L., Svane, Inge Marie, Olesen, U. H. & Hædersdal, Merete, 2022, In: Cancers. 14, 23, 5815.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types
Willumsen, N., Jensen, C., Green, G., Nissen, N. I., Neely, J., Nelson, D. M., Pedersen, R. S., Frederiksen, P., Chen, I. M., Boisen, M. K., Johansen, A. Z., Madsen, D. H., Svane, I. M., Lipton, A., Leitzel, K., Ali, S. M., Erler, J. T., Hurkmans, D. P., Mathijssen, R. H. J., Aerts, J. & 5 others, Eslam, M., George, J., Christiansen, C., Bissel, M. J. & Karsdal, M. A., 2022, In: Cellular and Molecular Life Sciences. 79, 4, 11 p., 204.
Research output: Contribution to journal › Review › Research › peer-review
Published
Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy
Chamberlain, C. A., Bennett, Eric Paul, Kverneland, Anders Handrup, Svane, Inge Marie, dqp123, dqp123 & Met, Özcan, 2022, In: Molecular Therapy - Oncolytics. 24, p. 417-428 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hud, blod og lymfesystem
Hendel, Helle Westergren, Chakera, A. H., Svane, Inge Marie, Pedersen, Lars Møller, Oturai, P. S., Jensen, M. R. & Glenthøj, Andreas Birkedal, 2022, Klinisk Nuklearmedicin. Munksgaard , p. 187-220
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
Published
Manufacture of adoptive cell therapies at academic cancer centers: scientific, safety and regulatory challenges
Saini, K. S., Svane, Inge Marie, Juan, M., Barlesi, F. & André, F., 2022, In: Annals of Oncology. 33, 1, p. 6-12 7 p.
Research output: Contribution to journal › Editorial › Research › peer-review
Published
Neoantigen-reactive CD8⁺ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma
Kristensen, N. P., Heeke, C., Tvingsholm, S. A., Borch, A., Draghi, A., Crowther, M. D., Carri, I., Munk, K. K., Holm, J. S., Bjerregaard, A. M., Bentzen, A. K., Marquard, A. M., Szallasi, Z., McGranahan, N., Andersen, R., Nielsen, M., Jönsson, G. B., dqp123, dqp123, Svane, Inge Marie & Hadrup, S. R., 2022, In: Journal of Clinical Investigation. 132, 2, p. 1-16 150535.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment
Bendtsen, S. K., Perez Penco, Maria, Hübbe, M. L., Martinenaite, E., Orebo Holmström, M., Weis-Banke, S. E., Grønne Dahlager Jørgensen, N., Jørgensen, M. A., Munir Ahmad, S., Jensen, K. M., Friese, C., Lundsager, M. T., Johansen, A. Z., Carretta, M., Ødum, Niels, Met, Özcan, Svane, Inge Marie, Madsen, Daniel Hargbøl & Andersen, Mads Hald, 2022, In: OncoImmunology. 11, 1, 2026020.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st–2nd, 2021
Ascierto, P. A., Avallone, A., Bhardwaj, N., Bifulco, C., Bracarda, S., Brody, J. D., Buonaguro, L., Demaria, S., Emens, L. A., Ferris, R. L., Galon, J., Khleif, S. N., Klebanoff, C. A., Laskowski, T., Melero, I., Paulos, C. M., Pignata, S., Ruella, M., Svane, I. M., Taube, J. M. & 3 others, Fox, B. A., Hwu, P. & Puzanov, I., 2022, In: Journal of Translational Medicine. 20, 1, 257.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Randomized Phase II Study of Nivolumab with or Without Ipilimumab Combined with Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC)
Chen, I. M., Johansen, Julia Sidenius, Theile, S., Hjaltelin, Jessica Xin, Novitski, Sif Ingibergsdóttir, Brunak, Søren, Hasselby, Jane Preuss, Willemoe, G. L., Lorentzen, T., Madsen, K., Jensen, B. V., Wilken, E. E., Geertsen, P., Behrens, C., Nolsøe, Christian, Hermann, K. L., Svane, Inge Marie & Nielsen, Dorte Lisbet, 2022, In: Journal of Clinical Oncology. 40, 27, p. 3180-3189
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Real-world data on melanoma brain metastases and survival outcome
Pedersen, S., Møller, Søren, dqp123, dqp123, Persson, Gitte F., Svane, Inge Marie & Ellebaek, E., 2022, In: Melanoma Research. 32, 3, p. 173-182 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Safety and efficacy of infliximab and corticosteroid therapy in checkpoint inhibitor-induced colitis
Dahl, E. K., Abed, O. K., Kjeldsen, J., dqp123, dqp123, Svane, Inge Marie, Dige, A., Agnholt, J. S., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, 2022, In: Alimentary Pharmacology and Therapeutics. 56, 9, p. 1370-1382 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tofacitinib and faecal microbiota transplantation in treating checkpoint inhibitor-induced enterocolitis: case report
Holmstroem, R. B., Dahl, E. K., Helms, Morten, Nielsen, H. V., Andersen, J. B., Bjerrum, Jakob Tveiten , Svane, Inge Marie, Ellebaek, E. & Seidelin, Jakob Benedict, 2022, In: BMJ Open Gastroenterology. 9, 1, 4 p., e000989.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Transcriptomic signatures of tumors undergoing T cell attack
Gokuldass, A., Schina, A., Lauss, M., Harbst, K., Chamberlain, C. A., Draghi, A., Westergaard, M. C. W., Nielsen, M., Papp, K., Sztupinszki, Z., Csabai, I., Svane, Inge Marie, Szallasi, Z., Jönsson, G. & dqp123, dqp123, 2022, In: Cancer Immunology, Immunotherapy. 71, 3, p. 553-563 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma.
Rohaan, M. W., Borch, T. H., Van Den Berg, J. H., Met, Ö., Kessels, R., Geukes Foppen, M. H., Stoltenborg Granhøj, J., Nuijen, B., Nijenhuis, C., Jedema, I., Van Zon, M., Scheij, S., Beijnen, J. H., Hansen, M., Voermans, C., Noringriis, I. M., Monberg, T. J., Holmstroem, R. B., Wever, L. D. V., Van Dijk, M. & 37 others, Grijpink-Ongering, L. G., Valkenet, L. H. M., Torres Acosta, A., Karger, M., Borgers, J. S. W., Ten Ham, R. M. T., Retèl, V. P., Van Harten, W. H., Lalezari, F., Van Tinteren, H., Van Der Veldt, A. A. M., Hospers, G. A. P., Stevense-Den Boer, M. A. M., Suijkerbuijk, K. P. M., Aarts, M. J. B., Piersma, D., Van Den Eertwegh, A. J. M., De Groot, J. W. B., Vreugdenhil, G., Kapiteijn, E., Boers-Sonderen, M. J., Fiets, W. E., Van Den Berkmortel, F. W. P. J., Ellebaek, E., Hølmich, Lisbet Rosenkrantz, Van Akkooi, A. C. J., Van Houdt, W. J., Wouters, M. W. J. M., Van Thienen, J. V., Blank, C. U., Meerveld-Eggink, A., Klobuch, S., Wilgenhof, S., Schumacher, T. N., dqp123, dqp123, Svane, Inge Marie & Haanen, J. B. A. G., 2022, In: New England Journal of Medicine. 387, 23, p. 2113-2125 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tumor-infiltrating lymphocytes for adoptive cell therapy: recent advances, challenges, and future directions
Granhøj, J. S., Jensen, Agnete Witness Præst, Presti, M., Met, Özcan, Svane, Inge Marie & dqp123, dqp123, 2022, In: Expert Opinion on Biological Therapy. 22, 5, p. 627-641 15 p.
Research output: Contribution to journal › Review › Research › peer-review
2021
Published
Bone marrow toxicity and immune reconstitution in melanoma and non-melanoma solid cancer patients after non-myeloablative conditioning with chemotherapy and checkpoint inhibition
Kverneland, Anders Handrup, Borch, T. H., Granhøj, J., Sengeløv, Henrik, Donia, M. & Svane, Inge Marie, Aug 2021, In: Cytotherapy. 23, 8, p. 724-729 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The Danish metastatic melanoma database (DAMMED): A nation-wide platform for quality assurance and research in real-world data on medical therapy in Danish melanoma patients
Ellebaek, E., Svane, Inge Marie, Schmidt, H., Haslund, C. A., dqp123, dqp123, Hoejberg, L., Ruhlmann, C., Guldbrandt, L. M., Køhler, U. H. & Bastholt, L., Aug 2021, In: Cancer Epidemiology. 73, 7 p., 101943.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immune check point inhibitors are associated with a spectrum of cardiac events in patients with cancer
D’souza, M., Svane, Inge Marie, Gislason, Gunnar Hilmar & Schou, Morten, 21 Apr 2021, In: European Heart Journal. 42, 16, p. 1636-1636 1 p.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types
Araujo B. de Lima, V., Hansen, M., Spanggaard, I., Rohrberg, K., Reker Hadrup, S., Lassen, Ulrik Niels & Svane, Inge Marie, 25 Mar 2021, In: Frontiers in Oncology. 11, 11 p., 558248.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Therapeutic Cancer Vaccination With a Peptide Derived From the Calreticulin Exon 9 Mutations Induces Strong Cellular Immune Responses in Patients With CALR-Mutant Chronic Myeloproliferative Neoplasms
Handlos Grauslund, J., Holmström, M. O., Jørgensen, N. G., Klausen, U., Weis-Banke, S. E., El Fassi, D., Schöllkopf, C., Clausen, M. B., Gjerdrum, L. M. R., Breinholt, M. F., Kjeldsen, J. W., Hansen, M., Koschmieder, S., Chatain, N., Novotny, G. W., Petersen, J., Kjær, L., Skov, V., Met, Ö., Svane, I. M. & 2 others, Hasselbalch, Hans Carl & Andersen, Mads Hald, 26 Feb 2021, In: Frontiers in Oncology. 11, 17 p., 637420.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner
Holmström, M. O., Mortensen, R. E. J., Pavlidis, A. M., Martinenaite, E., Weis-Banke, S. E., Aaboe-Jørgensen, M., Bendtsen, S. K., Met, Özcan, Pedersen, A. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, Feb 2021, In: Cellular and Molecular Immunology. 18, 2, p. 415-426 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Neurologiske bivirkninger af cancerimmunterapi med checkpointinhibitorer
Stenör, C., Ellebæk, E., El Mahdaoui, S. & Svane, Inge Marie, 11 Jan 2021, In: Ugeskrift for Laeger. 183, 2, 9 p., V05200406.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma
Kjeldsen, J. W., Lorentzen, C. L., Martinenaite, E., Ellebaek, E., dqp123, dqp123, Holmstroem, R. B., Klausen, T. W., Madsen, C. O., Ahmed, S. M., Weis-Banke, S. E., Holmström, M. O., Hendel, Helle Westergren, Ehrnrooth, E., Zocca, M. B., Pedersen, A. W., Andersen, Mads Hald & Svane, Inge Marie, 2021, In: Nature Medicine. 27, p. pages2212–2223
Research output: Contribution to journal › Journal article › Research › peer-review
Published
ACT Up TIL Now: The Evolution of Tumor-Infiltrating Lymphocytes in Adoptive Cell Therapy for the Treatment of Solid Tumors
Morgan Hulen , T., Chamberlain, C. A., Svane, Inge Marie & Met, Özcan, 2021, In: Immuno. 1, 3, p. 194-211
Research output: Contribution to journal › Journal article › Research › peer-review
Published
An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma
Klausen, U., Grønne Dahlager Jørgensen, N., Grauslund, J. H., Munir Ahmad, S., Gang, Anne Ortved, Martinenaite, E., Weis-Banke, S. E., Breinholt, M. F., Novotny, G. W., Kjeldsen, J. W., Orebo Holmström, M., Pedersen, L. B., Poulsen, C. B., Hansen, P. B., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2021, In: OncoImmunology. 10, 1, 1975889.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma
Borch, T. H., Harbst, K., Rana, A. H., Andersen, R., Martinenaite, E., Kongsted, P., Pedersen, M., Nielsen, M., Kjeldsen, J. W., Kverneland, Anders Handrup, Lauss, M., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Met, Özcan, Jönsson, G., dqp123, dqp123 & Svane, Inge Marie, 2021, In: Journal for ImmunoTherapy of Cancer. 9, 7, 15 p., e00270.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comparison of efficacy in patients with metastatic melanoma treated with ipilimumab and nivolumab who did or did not discontinue treatment due to immune-related adverse events: A real-world data study
Fink, M., Vittrup, A. S., Bastholt, L., Svane, Inge Marie, dqp123, dqp123, Luczak, A. A., Ruhlmann, C. H., Guldbrandt, L. M., Koehler, U. H., Winther, M. L., Ellebaek, E., Haslund, C. A. & Schmidt, H., 2021, In: Cancers. 13, 21, 10 p., 5550.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Crossover and rechallenge with pembrolizumab in recurrent patients from the EORTC 1325-MG/Keynote-054 phase III trial, pembrolizumab versus placebo after complete resection of high-risk stage III melanoma
Eggermont, A. M. M., Meshcheryakov, A., Atkinson, V., Blank, C. U., Mandala, M., Long, G. V., Barrow, C., Di Giacomo, A. M., Fisher, R., Sandhu, S., Kudchadkar, R., Romero, P. L. O., Svane, I. M., Larkin, J., Puig, S., Hersey, P., Quaglino, P., Queirolo, P., Stroyakovskiy, D., Bastholt, L. & 14 others, Mohr, P., Hernberg, M., Chiarion-Sileni, V., Strother, M., Hauschild, A., Yamazaki, N., van Akkooi, A. C., Lorigan, P., Krepler, C., Ibrahim, N., Marreaud, S., Kicinski, M., Suciu, S. & Robert, C., 2021, In: European Journal of Cancer. 158, p. 156-168 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Laser immunotherapy: A potential treatment modality for keratinocyte carcinoma
Omland, S. H., Wenande, E. C., Svane, Inge Marie, Tam, J., Olesen, U. H. & Hædersdal, Merete, 2021, In: Cancers. 13, 21, 18 p., 5405.
Research output: Contribution to journal › Review › Research › peer-review
Published
Lynch syndrome-associated epithelial ovarian cancer and its immunological profile
Rasmussen, M., Lim, K., Rambech, E., Andersen, Mads Hald, Svane, Inge Marie, Andersen, Ove, Jensen, L. H., Nilbert, Mef Christina & Therkildsen, C., 2021, In: Gynecologic Oncology. 162, 3, p. 686-693
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation
Duraiswamy, J., Turrini, R., Minasyan, A., Barras, D., Crespo, I., Grimm, A. J., Casado, J., Genolet, R., Benedetti, F., Wicky, A., Ioannidou, K., Castro, W., Neal, C., Moriot, A., Renaud-Tissot, S., Anstett, V., Fahr, N., Tanyi, J. L., Eiva, M. A., Jacobson, C. A. & 16 others, Montone, K. T., Westergaard, M. C. W., Svane, Inge Marie, Kandalaft, L. E., Delorenzi, M., Sorger, P. K., Färkkilä, A., Michielin, O., Zoete, V., Carmona, S. J., Foukas, P. G., Powell, D. J., Rusakiewicz, S., Doucey, M. A., Dangaj Laniti, D. & Coukos, G., 2021, In: Cancer Cell. 39, 12, p. 1623-1642.e20
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Rapid Identification of the Tumor-Specific Reactive TIL Repertoire via Combined Detection of CD137, TNF, and IFNϒ, Following Recognition of Autologous Tumor-Antigens
Draghi, A., Chamberlain, C. A., Khan, S., Papp, K., Lauss, M., Soraggi, S., Radic, H. D., Presti, M., Harbst, K., Gokuldass, A., Kverneland, Anders Handrup, Nielsen, M., Westergaard, M. C. W., Andersen, Mads Hald, Csabai, I., Jönsson, G., Szallasi, Z., Svane, Inge Marie & dqp123, dqp123, 2021, In: Frontiers in Immunology. 12, 13 p., 705422.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Real-time monitoring of mitochondrial respiration in cytokine-differentiated human primary T cells
Mølgaard, K., Rahbech, A., Met, Özcan, Svane, Inge Marie, Straten, P., Desler, Claus & Peeters, M. J. W., 2021, In: Journal of Visualized Experiments. 176, e62984.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The capacity of CD4⁺ Vγ9Vδ2 T cells to kill cancer cells correlates with co-expression of CD56
Holmen Olofsson, G., Pedersen, S. R., Aehnlich, P., Svane, Inge Marie, Idorn, M. & thor Straten, P., 2021, In: Cytotherapy. 23, 7, p. 582-589
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The effects of targeted immune-regulatory strategies on tumor-specific T-cell responses in vitro
Presti, M., Westergaard, M. C. W., Draghi, A., Chamberlain, C. A., Gokuldass, A., Svane, Inge Marie & dqp123, dqp123, 2021, In: Cancer Immunology, Immunotherapy. 70, p. 1771–1776
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The risk of cardiac events in patients receiving immune checkpoint inhibitors: a nationwide Danish study
D’souza, M., Nielsen, Dorte Lisbet, Svane, Inge Marie, Iversen, Kasper, Rasmussen, P. V., Madelaire, C., Fosbøl, E., Køber, Lars Valeur, Gustafsson, Finn, Andersson, C., Gislason, Gunnar Hilmar, Torp-Pedersen, Christian & Schou, Morten, 2021, In: European Heart Journal. 42, 16, p. 1621-1631
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vaccination against pd-l1 with io103 a novel immune modulatory vaccine in basal cell carcinoma: A phase iia study
Jørgensen, N. G., Kaae, Jeanette, Grauslund, J. H., Met, Özcan, Nielsen, S. L., Pedersen, A. W., Svane, Inge Marie, Ehrnrooth, E., Andersen, Mads Hald, Zachariae, Claus & Skov, Lone, 2021, In: Cancers. 13, 4, p. 1-15 15 p., 911.
Research output: Contribution to journal › Journal article › Research › peer-review
2020
Published
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity
Litchfield, K., Reading, J. L., Lim, E. L., Xu, H., Liu, P., Al-bakir, M., Wong, Y. N. S., Rowan, A., Funt, S. A., Merghoub, T., Perkins, D., Lauss, M., Svane, Inge Marie, Jönsson, G., Herrero, J., Larkin, J., Quezada, S. A., Hellmann, M. D., Turajlic, S. & Swanton, C., 1 Dec 2020, In: Nature Communications. 11, 1, 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cutaneous adverse reactions to anti–PD-1 treatment—A systematic review
Simonsen, Anne Birgitte Nørremark, Kaae, Jeanette, Ellebaek, E., Svane, Inge Marie & Zachariae, Claus, 1 Nov 2020, In: Journal of the American Academy of Dermatology. 83, 5, p. 1415-1424 10 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome
Araujo B de Lima, V., Borch, A., Hansen, M., Draghi, A., Spanggaard, I., Rohrberg, K., Reker Hadrup, S., Lassen, Ulrik Niels & Svane, Inge Marie, Apr 2020, In: Cytotherapy. 22, 4, p. 204-213 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer
Kverneland, Anders Handrup, Pedersen, M., Wulff Westergaard, M. C., Nielsen, M., Borch, T. H., Olsen, L. R., Aasbjerg, G., Santegoets, S. J., van der Burg, S. H., Milne, K., Nelson, B. H., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: OncoTarget. 11, 22, p. 2092-2105 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
CTLA-4 blockade boosts the expansion of tumor-reactive CD8⁺ tumor-infiltrating lymphocytes in ovarian cancer
Friese, C., Harbst, K., Borch, T. H., Westergaard, M. C. W., Pedersen, M., Kverneland, A., Jönsson, G., dqp123, dqp123, Svane, Inge Marie & Met, Özcan, 2020, In: Scientific Reports. 10, 1, 12 p., 3914.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Changes in the Tumor Immune Microenvironment during Disease Progression in Patients with Ovarian Cancer
Westergaard, M. C. W., Milne, K., Pedersen, M., Hasselager, T., Olsen, L. R., Anglesio, M. S., Borch, T. H., Kennedy, M., Briggs, G., Ledoux, S., Kreuzinger, C., Decken, I. V. D., Donia, M., Castillo-Tong, D. C., Nelson, B. H. & Svane, Inge Marie, 2020, In: Cancers. 12, 12, 19 p., 3828.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Characterization of risk factors and efficacy of medical management of immune-related hepatotoxicity in real-world patients with metastatic melanoma treated with immune checkpoint inhibitors
Romanski, N. A., Holmstroem, R. B., Ellebaek, E. & Svane, Inge Marie, 2020, In: European Journal of Cancer. 130, p. 211-218
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Future role for adoptive T-cell therapy in checkpoint inhibitor-resistant metastatic melanoma
Borch, T. H., Andersen, R., Ellebaek, E., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, e000668.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Genetic biomarkers in melanoma of the ocular region: What the medical oncologist should know
Bol, K. F., dqp123, dqp123, Heegaard, Steffen, Kiilgaard, Jens Folke & Svane, Inge Marie, 2020, In: International Journal of Molecular Sciences . 21, 15, p. 1-14 14 p., 5231.
Research output: Contribution to journal › Review › Research › peer-review
Published
Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1
Crowther, M. D., Dolton, G., Legut, M., Caillaud, M. E., Lloyd, A., Attaf, M., Galloway, S. A. E., Rius, C., Farrell, C. P., Szomolay, B., Ager, A., Parker, A. L., Fuller, A., dqp123, dqp123, McCluskey, J., Rossjohn, J., Svane, Inge Marie, Phillips, J. D. & Sewell, A. K., 2020, In: Nature Immunology. 21, 2, p. 178-185 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Granzyme B Degraded Type IV Collagen Products in Serum Identify Melanoma Patients Responding to Immune Checkpoint Blockade
Jensen, C., Sinkeviciute, D., Madsen, D. H., Onnerfjord, P., Hansen, M., Schmidt, H., Karsdal, M. A., Svane, Inge Marie & Willumsen, N., 2020, In: Cancers. 12, 10, p. 1-15 2786.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Improved progression-free long-term survival of a nation-wide patient population with metastatic melanoma
Soerensen, A. V., Ellebaek, E., Bastholt, L., Schmidt, H., dqp123, dqp123 & Svane, Inge Marie, 2020, In: Cancers. 12, 9, p. 1-11 11 p., 2591.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In vitro 4-1BB stimulation promotes expansion of CD8⁺ tumor-infiltrating lymphocytes from various sarcoma subtypes
Nielsen, M., Krarup-Hansen, Anders, Hovgaard, D., Petersen, Michael Mørk, Loya, Anand Chainsukh, Westergaard, M. C. W., Svane, Inge Marie & Junker, N., 2020, In: Cancer Immunology, Immunotherapy. 69, p. 2179-2191
Research output: Contribution to journal › Journal article › Research › peer-review
Published
KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma
Ferrucci, P. F., Di Giacomo, A. M., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G. V., Stephens, R., Svane, Inge Marie, Lotem, M., Abu-Amna, M., Gasal, E., Ghori, R., Diede, S. J., Croydon, E. S., Ribas, A., Ascierto, P. A. & KEYNOTE-022 international team, K. I. T., 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, 8 p., e001806.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Overall survival at 5 years of follow-up in a phase III trial comparing ipilimumab 10 mg/kg with 3 mg/kg in patients with advanced melanoma
Ascierto, P. A., Del Vecchio, M., Mackiewicz, A., Robert, C., Chiarion-Sileni, V., Arance, A., Lebbé, C., Svane, I. M., Mcneil, C., Rutkowski, P., Loquai, C., Mortier, L., Hamid, O., Bastholt, L., Dreno, B., Schadendorf, D., Garbe, C., Nyakas, M., Grob, J. J., Thomas, L. & 10 others, Liszkay, G., Smylie, M., Hoeller, C., Ferraresi, V., Grange, F., Gutzmer, R., Pikiel, J., Hosein, F., Simsek, B. & Maio, M., 2020, In: Journal for ImmunoTherapy of Cancer. 8, 1, e000391.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peptide Vaccination Against PD-L1 With IO103 a Novel Immune Modulatory Vaccine in Multiple Myeloma: A Phase I First-in-Human Trial
Jørgensen, N. G., Klausen, U., Grauslund, J. H., Helleberg, C., Aagaard, T. G., Do, T. H., Ahmad, S. M., Olsen, L. R., Klausen, T. W., Breinholt, M. F., Hansen, M., Martinenaite, E., Met, Özcan, Svane, Inge Marie, Knudsen, L. M. & Andersen, Mads Hald, 2020, In: Frontiers in Immunology. 11, 11 p., 595035.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Qualitative analysis of tumor-infiltrating lymphocytes across human tumor types reveals a higher proportion of bystander CD8⁺ T cells in non-melanoma cancers compared to melanoma
Gokuldass, A., Draghi, A., Papp, K., Borch, T. H., Nielsen, M., Westergaard, M. C. W., Andersen, R., Schina, A., Bol, K. F., Chamberlain, C. A., Presti, M., Met, Özcan, Harbst, K., Lauss, M., Soraggi, S., Csabai, I., Szállási, Z., Jönsson, G., Svane, Inge Marie & dqp123, dqp123, 2020, In: Cancers. 12, 11, p. 1-15 15 p., 3344.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road
Crowther, M. D., Svane, Inge Marie & Met, Özcan, 2020, In: Cells. 9, 7, 18 p., 1588.
Research output: Contribution to journal › Review › Research › peer-review
Published
Tertiary lymphoid structures improve immunotherapy and survival in melanoma
Cabrita, R., Lauss, M., Sanna, A., Donia, M., Skaarup Larsen, M., Mitra, S., Johansson, I., Phung, B., Harbst, K., Vallon-Christersson, J., van Schoiack, A., Lövgren, K., Warren, S., Jirström, K., Olsson, H., Pietras, K., Ingvar, C., Isaksson, K., Schadendorf, D., Schmidt, H. & 5 others, Bastholt, L., Carneiro, A., Wargo, J. A., Svane, Inge Marie & Jönsson, G., 2020, In: Nature. 577, p. 561-565
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The metabolic enzyme arginase-2 is a potential target for novel immune modulatory vaccines
Weis-Banke, S. E., Hübbe, M. L., Holmström, M. O., Jørgensen, M. A., Bendtsen, S. K., Martinenaite, E., Carretta, M., Svane, Inge Marie, Ødum, Niels, Pedersen, A. W., Met, Özcan, Madsen, D. H. & Andersen, Mads Hald, 2020, In: OncoImmunology. 9, 1, 16 p., 1771142.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations
Hansen, U. K., Ramskov, S., Bjerregaard, A. M., Borch, A., Andersen, R., Draghi, A., dqp123, dqp123, Bentzen, A. K., Marquard, A. M., Szallasi, Z., Eklund, A. C., Svane, Inge Marie & Hadrup, S. R., 2020, In: Frontiers in Immunology. 11, 373.
Research output: Contribution to journal › Journal article › Research › peer-review
2019
Published
The real-world outcome of metastatic melanoma: Unknown primary vs. known cutaneous
Ellebaek, E., Bastholt, L., Schmidt, H., Svane, Inge Marie & dqp123, dqp123, 1 Dec 2019, In: International Journal of Cancer. 145, 11, p. 3173-3174 2 p.
Research output: Contribution to journal › Letter › Research › peer-review
Published
Age favoured overall survival in a large population-based Danish patient cohort treated with anti-PD1 immune checkpoint inhibitor for metastatic melanoma
Bastholt, L., Schmidt, H., Bjerregaard, J. K., Herrstedt, Jørn & Svane, Inge Marie, Sep 2019, In: European journal of cancer (Oxford, England : 1990). 119, p. 122-131 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High-dose interleukin-2 and interferon as first-line immunotherapy for metastatic melanoma: long-term follow-up in a large unselected Danish patient cohort
Bastholt, L., Svane, Inge Marie, Bjerregaard, J. K., Herrstedt, Jørn, Hróbjartsson, A. & Schmidt, H., Jul 2019, In: European journal of cancer (Oxford, England : 1990). 115, p. 61-67
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Principles of adoptive T cell therapy in cancer
Met, Özcan, Jensen, K. M., Chamberlain, C. A., dqp123, dqp123 & Svane, Inge Marie, 11 Jan 2019, In: Seminars in Immunopathology. 41, 1, p. 49–58
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Arginase-1-based vaccination against the tumor microenvironment: the identification of an optimal T-cell epitope
Martinenaite, E., Ahmad, S. M., Bendtsen, S. K., Jørgensen, M. A., Weis-Banke, S. E., Svane, Inge Marie & Andersen, Mads Hald, 2019, In: Cancer Immunology, Immunotherapy. 68, 11, p. 1901-1907 7 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Assessment of extracellular matrix and tissue derived metabolites in a liquid biopsy for identifying endotypes of metastatic melanoma patients with differential response to immune checkpoint inhibitor treatment.
Willumsen, N., Bager, C. L., Jensen, C., Karsdal, M. A., Madsen, Daniel Hargbøl, Hansen, M., Schmidt, H. & Svane, Inge Marie, 2019, In: Journal of Clinical Oncology. 37, 15_suppl, e14050.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
B-cell frequencies and immunoregulatory phenotypes in myeloproliferative neoplasms: influence of ruxolitinib, interferon-α2, or combination treatment
Sørensen, A. L., Bjørn, M. E., Riley, C. H., Holmstrøm, M., Andersen, Mads Hald, Svane, Inge Marie, Mikkelsen, S. U., Skov, V., Kjær, L., Hasselbalch, H. C. & Nielsen, C. H., 2019, In: European Journal of Haematology. 103, 4, p. 351-361 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cancerimmunterapi til behandling af hæmatologisk cancer
Holmström, M. O., Klausen, U., Jørgensen, N. G., Holmberg, S., Grauslund, J., Met, Ö., Svane, Inge Marie, Pedersen, Lars Møller, Knudsen, L. M., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: Ugeskrift for Laeger. 181, 10, 5 p., V06180421.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chimeric antigen receptor-T-cellebehandling
Muller, Klaus, Ifversen, M., Kielsen, K., Petersen, S. L., Met, Ö. & Svane, Inge Marie, 2019, In: Ugeskrift for Laeger. 181, 20A, 5 p., V05190309.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Collagen density regulates the activity of tumor-infiltrating T cells
Kuczek, D. E., Larsen, A. M. H., Thorseth, M., Carretta, M., Kalvisa, A., Siersbæk, M. S., Simões, A. M. C., Roslind, A., Engelholm, Lars Henning, Noessner, E., dqp123, dqp123, Svane, Inge Marie, Straten, P. T., Grøntved, L. & Madsen, D. H., 2019, In: Journal for ImmunoTherapy of Cancer. 7, 1, 15 p., 68.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma
Ascierto, P. A., Ferrucci, P. F., Fisher, R., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G. V., Di Giacomo, A. M., Svane, Inge Marie, Lotem, M., Bar-Sela, G., Couture, F., Mookerjee, B., Ghori, R., Ibrahim, N., Moreno, B. H. & Ribas, A., 2019, In: Nature Medicine. 25, 6, p. 941-946 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Differential effects of corticosteroids and anti-TNF on tumor-specific immune responses: implications for the management of irAEs
Draghi, A., Borch, T. H., Radic, H. D., Chamberlain, C. A., Gokuldass, A., Svane, Inge Marie & dqp123, dqp123, 2019, In: International Journal of Cancer. 145, 5, p. 1408-1413 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma
Jansen, Y. J. L., Rozeman, E. A., Mason, R., Goldinger, S. M., Geukes Foppen, M. H., Højberg, L., Schmidt, H., van Thienen, J. V., Haanen, J. B. A. G., Tiainen, L., Svane, I. M., Mäkelä, S., Seremet, T., Arance, A., Dummer, R., Bastholt, L., Nyakas, M., Straume, O., Menzies, A. M., Long, G. V. & 3 others, Atkinson, V., Blank, C. U. & Neyns, B., 2019, In: Annals of Oncology. 30, 7, p. 1154-1161 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis
Dafni, U., Michielin, O., Lluesma, S. M., Tsourti, Z., Polydoropoulou, V., Karlis, D., Besser, M. J., Haanen, J., Svane, Inge Marie, Ohashi, P. S., Kammula, U. S., Orcurto, A., Zimmermann, S., Trueb, L., Klebanoff, C. A., Lotze, M. T., Kandalaft, L. E. & Coukos, G., 2019, In: Annals of Oncology. 30, 12, p. 1902-1913 12 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells
Saini, S. K., Tamhane, T., Anjanappa, R., Saikia, A., Ramskov, S., dqp123, dqp123, Svane, Inge Marie, Jakobsen, S. N., Garcia-Alai, M., Zacharias, M., Meijers, R., Springer, S. & Hadrup, S. R., 2019, In: Science immunology. 4, 37, eaau9039.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Evaluation of Two Dosing Regimens for Nivolumab in Combination With Ipilimumab in Patients With Advanced Melanoma: Results From the Phase IIIb/IV CheckMate 511 Trial
Lebbé, C., Meyer, N., Mortier, L., Marquez-Rodas, I., Robert, C., Rutkowski, P., Menzies, A. M., Eigentler, T., Ascierto, P. A., Smylie, M., Schadendorf, D., Ajaz, M., Svane, Inge Marie, Gonzalez, R., Rollin, L., Lord-Bessen, J., Saci, A., Grigoryeva, E. & Pigozzo, J., 2019, In: Journal of Clinical Oncology. 37, 11, p. 867-875
Research output: Contribution to journal › Journal article › Research › peer-review
Published
HER2 CAR-T cells eradicate uveal melanoma and T-cell therapy–resistant human melanoma in IL2 transgenic NOD/SCID IL2 receptor knockout mice
Forsberg, E. M. V., Lindberg, M. F., Jespersen, H., Alsen, S., Bagge, R. O., dqp123, dqp123, Svane, Inge Marie, Nilsson, O., Ny, L., Nilsson, L. M. & Nilsson, J. A., 2019, In: Cancer Research. 79, 5, p. 899-904 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High frequencies of circulating memory T cells specific for calreticulin exon 9 mutations in healthy individuals
Holmström, M. O., Ahmad, S. M., Klausen, U., Bendtsen, S. K., Martinenaite, E., Riley, C. H., Svane, Inge Marie, Kjær, L., Skov, V., Ellervik, Christina, Pallisgaard, N., Hasselbalch, H. C. & Andersen, Mads Hald, 2019, In: Blood Cancer Journal. 9, 2, 8.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immunoprofiles of colorectal cancer from Lynch syndrome
Walkowska, J., Kallemose, T., Jönsson, G., Jönsson, M., Andersen, Ove, Andersen, Mads Hald, Svane, Inge Marie, Langkilde, A., Nilbert, Mef Christina & Therkildsen, C., 2019, In: OncoImmunology. 8, 1, 9 p., e1515612.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immunterapi til patienter med malignt melanom og hjernemetastaser
Simonsen, L. T., Schmidt, A. M. S., Øllegaard, T. H., Svane, Inge Marie, Bastholt, L., Luczak, A. A. & Schmidt, H., 2019, In: Ugeskrift for Laeger. 181, 24, 5 p., V01190057.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Long-Term Exposure to Inflammation Induces Differential Cytokine Patterns and Apoptosis in Dendritic Cells
Carstensen, L. S., Lie-Andersen, O., Obers, A., Crowther, M. D., Svane, Inge Marie & Hansen, M., 2019, In: Frontiers in Immunology. 10, 11 p., 2702.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
MERTK Acts as a costimulatory receptor on human cd8 t cells
Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Desler, Claus & Straten, P. T., 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peptide Super-Agonist Enhances T-Cell Responses to Melanoma
Galloway, S. A. E., Dolton, G., Attaf, M., Wall, A., Fuller, A., Rius, C., Bianchi, V., Theaker, S., Lloyd, A., Caillaud, M. E., Svane, Inge Marie, dqp123, dqp123, Cole, D. K., Szomolay, B., Rizkallah, P. & Sewell, A. K., 2019, In: Frontiers in Immunology. 10, 18 p., 319.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Peripheral memory T cells specific for Arginase-1
Martinenaite, E., Ahmad, S. M., Svane, Inge Marie & Andersen, Mads Hald, 2019, In: Cellular and Molecular Immunology. 16, 8, p. 718-719 2 p.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
Real-World Impact of Immune Checkpoint Inhibitors in Metastatic Uveal Melanoma
Bol, K. F., Ellebaek, E., Hoejberg, L., Bagger, M. M., Larsen, M. S., Klausen, T. W., Køhler, U. H., Schmidt, H., Bastholt, L., Kiilgaard, Jens Folke, dqp123, dqp123 & Svane, Inge Marie, 2019, In: Cancers. 11, 10, 11 p., 1489;.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Real-world evidence to guide healthcare policies in oncology
dqp123, dqp123, Hansen, S. W. & Svane, Inge Marie, 2019, In: OncoTarget. 10, 44, p. 4513-4515
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Survival Outcomes in Patients With Previously Untreated BRAF Wild-Type Advanced Melanoma Treated With Nivolumab Therapy: Three-Year Follow-up of a Randomized Phase 3 Trial
Ascierto, P. A., Long, G. V., Robert, C., Brady, B., Dutriaux, C., Di Giacomo, A. M., Mortier, L., Hassel, J. C., Rutkowski, P., McNeil, C., Kalinka-Warzocha, E., Savage, K. J., Hernberg, M. M., Lebbé, C., Charles, J., Mihalcioiu, C., Chiarion-Sileni, V., Mauch, C., Cognetti, F., Ny, L. & 8 others, Arance, A., Svane, Inge Marie, Schadendorf, D., Gogas, H., Saci, A., Jiang, J., Rizzo, J. & Atkinson, V., 2019, In: JAMA Oncology. 5, 2, p. 187-194
Research output: Contribution to journal › Journal article › Research › peer-review
Published
T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
Viborg, N., Ramskov, S., Andersen, R. S., Sturm, T., Fugmann, T., Bentzen, A. K., Rafa, V. M., Straten, P. T., Svane, Inge Marie, Met, Özcan & Hadrup, S. R., 2019, In: OncoImmunology. 8, 12, 11 p., 1663107.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The real-world impact of modern treatments on the survival of patients with metastatic melanoma
dqp123, dqp123, Ellebaek, E., Øllegaard, T. H., Duval, L., Aaby, J. B., Hoejberg, L., Køhler, U. H., Schmidt, H., Bastholt, L. & Svane, Inge Marie, 2019, In: European Journal of Cancer. 108, p. 25-32 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tumour-reactive T cell subsets in the microenvironment of ovarian cancer
Westergaard, M. C. W., Andersen, R., Chong, C., Kjeldsen, J. W., Pedersen, M., Friese, C., Hasselager, T., Lajer, H., Coukos, G., Bassani-Sternberg, M., dqp123, dqp123 & Svane, Inge Marie, 2019, In: British Journal of Cancer. 120, p. 424-434
Research output: Contribution to journal › Journal article › Research › peer-review
2018
Published
Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes
Kjaer, L., Holmström, M. O., Cordua, S., Andersen, Mads Hald, Svane, Inge Marie, Thomassen, M., Kruse, T. A., Pallisgaard, N., Skov, V. & Hasselbalch, Hans Carl, Apr 2018, In: Leukemia and Lymphoma. 59, 4, p. 973-977 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy
Holmstrom, M. O., Martinenaite, E., Ahmad, S. M., Met, Özcan, Friese, C., Kjaer, L., Riley, C. H., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 1 Feb 2018, In: Leukemia. 32, 2, p. 429-437
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Adoptive cell therapy with tumor-infiltrating lymphocytes in patients with metastatic ovarian cancer: a pilot study
Pedersen, M., Westergaard, M. C. W., Milne, K., Nielsen, M., Borch, T. H., Poulsen, L. G., Hendel, Helle Westergren, Kennedy, M., Briggs, G., Ledoux, S., Nøttrup, T. J., Andersen, P., Hasselager, T., Met, Ö., Nelson, B. H., dqp123, dqp123 & Svane, Inge Marie, 2018, In: OncoImmunology. 7, 12, 12 p., e1502905.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cancer immunotherapy in patients with brain metastases
Caponnetto, S., Draghi, A., Borch, T. H., Nuti, M., Cortesi, E., Svane, Inge Marie & dqp123, dqp123, 2018, In: Cancer Immunology, Immunotherapy. 67, 5, p. 703-711 9 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Cancerimmunterapi
Kjeldsen, J. W., dqp123, dqp123 & Svane, Inge Marie, 2018, In: Ugeskrift for Laeger. 180, 5 p., V09170691.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Checkpoint inhibitors in breast cancer - current status
Polk, A., Svane, Inge Marie, Andersson, M. & Nielsen, Dorte Lisbet, 2018, In: Cancer Treatment Reviews. 63, p. 122-134
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab
Kverneland, A. H., Enevold, C., dqp123, dqp123, Bastholt, L., Svane, Inge Marie & Nielsen, C. H., 2018, In: OncoImmunology. 7, 5, p. e1424674 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Durable clinical responses and long-term follow-up of stage III-IV non-small-cell lung cancer (NSCLC) patients treated with IDO peptide vaccine in a phase i study-a brief research report
Kjeldsen, J. W., Iversen, T. Z., Engell-Noerregaard, L., Mellemgaard, A., Andersen, Mads Hald & Svane, Inge Marie, 2018, In: Frontiers in Immunology. 9, SEP, 6 p., 2145.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Frequent adaptive immune responses against arginase-1
Martinenaite, E., Mortensen, R. E. J., Hansen, M., Orebo Holmström, M., Munir Ahmad, S., Grønne Dahlager Jørgensen, N., Met, Özcan, dqp123, dqp123, Svane, Inge Marie & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 3, 9 p., e1404215.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
Jensen, C., Madsen, D. H., Hansen, M., Schmidt, H., Svane, Inge Marie, Karsdal, M. A. & Willumsen, N., 2018, In: Journal for ImmunoTherapy of Cancer. 6, 1, p. 1-10 10 p., 152.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Novel Strategies for Peptide-Based Vaccines in Hematological Malignancies
Klausen, U., Holmberg, S., Holmstrom, M. O., Jorgensen, N. G. D., Grauslund, J. H., Svane, Inge Marie & Andersen, Mads Hald, 2018, In: Frontiers in Immunology. 9, 8 p., 2264.
Research output: Contribution to journal › Review › Research › peer-review
Published
Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations
Rius, C., Attaf, M., Tungatt, K., Bianchi, V., Legut, M., Bovay, A., dqp123, dqp123, Thor Straten, P., Peakman, M., Svane, Inge Marie, Ott, S., Connor, T., Szomolay, B., Dolton, G. & Sewell, A. K., 2018, In: The Journal of Immunology. 200, 7, p. 2263-2279
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Spontaneous T-cell responses against the immune check point programmed-death-ligand 1 (PD-L1) in patients with chronic myeloproliferative neoplasms correlate with disease stage and clinical response
Holmström, M. O., Riley, C. H., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 6, e1433521.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
T cells isolated from patients with checkpoint inhibitor-resistant melanoma are functional and can mediate tumor regression
Andersen, R., Borch, T. H., Draghi, A., Gokuldass, A., Rana, M. A. H., Pedersen, M., Nielsen, M., Kongsted, P., Kjeldsen, J. W., Westergaard, M. C. W., Radic, H. D., Chamberlain, C. A., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Larsen, M. S., Met, Özcan, Svane, Inge Marie & dqp123, dqp123, 2018, In: Annals of Oncology. 29, 7, p. 1575-1581 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
T-cell Responses in the Microenvironment of Primary Renal Cell Carcinoma-Implications for Adoptive Cell Therapy
Andersen, R., Westergaard, M. C. W., Kjeldsen, J. W., Müller, A., Pedersen, N. W., Hadrup, S. R., Met, Özcan, Seliger, B., Kromann-Andersen, B., Hasselager, T., dqp123, dqp123 & Svane, Inge Marie, 2018, In: Cancer Immunology Research. 6, 2, p. 222-235 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The inhibitory checkpoint, PD-L2, is a target for effector T cells: Novel possibilities for immune therapy
Ahmad, S. M., Martinenaite, E., Holmström, M., Jørgensen, M. A., Met, Özcan, Nastasi, C., Klausen, U., dqp123, dqp123, Pedersen, Lars Møller, Munksgaard, Lars, Ødum, Niels, Woetmann, Anders , Svane, Inge Marie & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 2, 10 p., e1390641.
Research output: Contribution to journal › Journal article › Research › peer-review
2017
Published
Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling
Donia, M., Harbst, K., van Buuren, M., Kvistborg, P., Lindberg, M. F., Andersen, R., Idorn, M., Munir Ahmad, S., Ellebæk, E., Mueller, A., Fagone, P., Nicoletti, F., Libra, M., Lauss, M., Hadrup, S. R., Schmidt, H., Andersen, M. H., Thor Straten, P., Nilsson, J. A., Schumacher, T. N. & 3 others, Seliger, B., Jönsson, G. & Svane, Inge Marie, 1 Sep 2017, In: Cancer Research. 77, 17, p. 4562-4566 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trial
Ascierto, P. A., Del Vecchio, M., Robert, C., Mackiewicz, A., Chiarion-Sileni, V., Arance, A., Lebbé, C., Bastholt, L., Hamid, O., Rutkowski, P., McNeil, C., Garbe, C., Loquai, C., Dreno, B., Thomas, L., Grob, J-J., Liszkay, G., Nyakas, M., Gutzmer, R., Pikiel, J. & 10 others, Grange, F., Hoeller, C., Ferraresi, V., Smylie, M., Schadendorf, D., Mortier, L., Svane, Inge Marie, Hennicken, D., Qureshi, A. & Maio, M., May 2017, In: Lancet Oncology. 18, 5, p. 611-622 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II study
Kongsted, P., Borch, T. H., Ellebaek, E., Iversen, T. Z., Andersen, R., Met, Özcan, Hansen, M., Lindberg, H., Sengeløv, L. & Svane, Inge Marie, 1 Apr 2017, In: Cytotherapy. 19, 4, p. 500-513 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cancer immunotherapy in patients with preexisting autoimmune disorders
dqp123, dqp123, Pedersen, M. & Svane, Inge Marie, Apr 2017, In: Seminars in Immunopathology. 39, 3, p. 333-337 5 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Clinical Impact of the Number of Treatment Cycles in First-Line Docetaxel for Patients With Metastatic Castration-Resistant Prostate Cancer
Kongsted, P., Svane, Inge Marie, Lindberg, H. & Sengeløv, L., Apr 2017, In: Clinical Genitourinary Cancer. 15, 2, p. e281-e287
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
Jespersen, H., Lindberg, M. F., dqp123, dqp123, Söderberg, E. M. V., Andersen, R., Keller, U., Ny, L., Svane, Inge Marie, Nilsson, L. M. & Nilsson, J. A., 2017, In: Nature Communications. 8, 10 p., 707.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immunterapi er kræftbehandling med en helt ny bivirkningsprofil
Kondrup, M., Raunkilde, L., Svane, Inge Marie, Schmidt, H. & Bastholt, L., 2017, In: Ugeskrift for Laeger. 179, 5 p., V05170365.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Indoleamine 2,3-dioxygenase and survivin peptide vaccine combined with temozolomide in metastatic melanoma
Nitschke, N. J., Bjoern, J., Iversen, T. Z., Andersen, Mads Hald & Svane, Inge Marie, 2017, In: Stem Cell Investigation. 4, 13 p., 77.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma
Bjoern, J., Lyngaa, R., Andersen, R., Hølmich, Lisbet Rosenkrantz, Hadrup, S. R., dqp123, dqp123 & Svane, Inge Marie, 2017, In: OncoTarget. 8, 16, p. 27062-27074
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
Lauss, M., dqp123, dqp123, Harbst, K., Andersen, R., Mitra, S., Rosengren, F., Salim, M., Vallon-Christersson, J., Törngren, T., Kvist, A., Ringnér, M., Svane, Inge Marie & Jönsson, G., 2017, In: Nature Communications. 8, 11 p., 1738.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
PD-1⁺ Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer
dqp123, dqp123, Kjeldsen, J. W., Andersen, R., Westergaard, M. C. W., Bianchi, V., Legut, M., Attaf, M., Szomolay, B., Ott, S., Dolton, G., Lyngaa, R., Hadrup, S. R., Sewell, A. K. & Svane, Inge Marie, 2017, In: Clinical Cancer Research. 23, 19, p. 5779-5788
Research output: Contribution to journal › Journal article › Research › peer-review
Published
PD-L1 expression and survival among melanoma patients treated with standard immunotherapy or chemotherapy
Steiniche, T., Vestergaard Danielsen, A., Wang, Z., Feng, Y., Switten Nielsen, P., Bastholt, L., Schmidt, H., Svane, Inge Marie, Dolled-Filhart, M., Emancipator, K., Weiner, R., Busch-Sørensen, M. & Zhou, W., 2017, In: Journal of the European Academy of Dermatology and Venereology. 31, 7, p. e319-e321
Research output: Contribution to journal › Comment/debate › Research
Published
Predictors of responses to immune checkpoint blockade in advanced melanoma
Jacquelot, N., Roberti, M. P., Enot, D. P., Rusakiewicz, S., Ternès, N., Jegou, S., Woods, D. M., Sodré, A. L., Hansen, M., Meirow, Y., Sade-Feldman, M., Burra, A., Kwek, S. S., Flament, C., Messaoudene, M., Duong, C. P. M., Chen, L., Kwon, B. S., Anderson, A. C., Kuchroo, V. K. & 30 others, Weide, B., Aubin, F., Borg, C., Dalle, S., Beatrix, O., Ayyoub, M., Balme, B., Tomasic, G., Di Giacomo, A. M., Maio, M., Schadendorf, D., Melero, I., Dréno, B., Khammari, A., Dummer, R., Levesque, M., Koguchi, Y., Fong, L., Lotem, M., Baniyash, M., Schmidt, H., Svane, Inge Marie, Kroemer, G., Marabelle, A., Michiels, S., Cavalcanti, A., Smyth, M. J., Weber, J. S., Eggermont, A. M. & Zitvogel, L., 2017, In: Nature Communications. 8, 13 p., 592.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
Buschow, S. I., Ramazzotti, M., Reinieren-Beeren, I. M. J., Heinzerling, L. M., Westdorp, H., Stefanini, I., Beltrame, L., Hato, S. V., Ellebaek, E., Gross, S., Nguyen, V. A., Weinlich, G., Ragoussis, J., Baban, D., Schuler-Thurner, B., Svane, I. M., Romani, N., Austyn, J. M., De Vries, I. J. M., Schuler, G. & 2 others, Cavalieri, D. & Figdor, C. G., 2017, In: OncoTarget. 8, 40, p. 67439-67456 18 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The JAK2V617F mutation is a target for specific T cells in the JAK2V617F-positive myeloproliferative neoplasms
Holmström, M. O., Hjortso, M. D., Ahmad, S. M., Met, Özcan, Martinenaite, E., Riley, C., Straten, P., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2017, In: Leukemia. 31, p. 495-498
Research output: Contribution to journal › Letter › Research › peer-review
Published
The majority of patients with metastatic melanoma are not represented in pivotal phase III immunotherapy trials
dqp123, dqp123, Kimper-Karl, M. L., Høyer, K. L., Bastholt, L., Schmidt, H. & Svane, Inge Marie, 2017, In: European Journal of Cancer. 74, p. 89-95
Research output: Contribution to journal › Journal article › Research › peer-review
2016
Published
Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma
Gjorup, C. A., Hendel, Helle Westergren, Svane, Inge Marie & Hølmich, Lisbet Rosenkrantz, 1 Dec 2016, In: J P R A S Open. 10, p. 1-4 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The CALR exon 9 mutations are shared neoantigens in patients with CALR mutant chronic myeloproliferative neoplasms
Holmström, M. O., Riley, C. H., Svane, Inge Marie, Hasselbalch, H. C. & Andersen, Mads Hald, Dec 2016, In: Leukemia. 30, 12, p. 2413-2416 14 p.
Research output: Contribution to journal › Letter › Research › peer-review
Published
The Danish Melanoma Database
Hølmich, Lisbet Rosenkrantz, Klausen, S., Spaun, E., Schmidt, G., Gad, D., Svane, Inge Marie, Schmidt, H., Lorentzen, H. F. & Ibfelt, E. H., 25 Oct 2016, In: Clinical Epidemiology. 8, p. 543-548 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes
Bentzen, A. K., Marquard, A. M., Lyngaa, R., Saini, S. K., Ramskov, S., Donia, M., Such, L., Furness, A. J. S., McGranahan, N., Rosenthal, R., thor Straten, E. P., Szallasi, Z., Svane, Inge Marie, Swanton, C., Quezada, S. A., Jakobsen, S. N., Eklund, A. C. & Hadrup, S. R., Oct 2016, In: Nature Biotechnology. 34, 10, p. 1037-1045 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Therapeutic Vaccination against A Modified Minimal Survivin Epitope Induces Functional CD4 T Cells That Recognize Survivin-Expressing Cells
Nitschke, N. J., Bjoern, J., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 1 Sep 2016, In: Scandinavian Journal of Immunology. 84, 3, p. 191-193 3 p.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma
Borch, T. H., Engell-Noerregaard, L., Iversen, T. Z., Ellebaek, E., Met, Özcan, Hansen, M., Andersen, Mads Hald, thor Straten, E. P. & Svane, Inge Marie, 1 Sep 2016, In: OncoImmunology. 5, 9, 12 p., e1207842.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Autocrine CCL19 blocks dendritic cell migration toward weak gradients of CCL21
Hansen, M., Met, Özcan, Larsen, N. B., Rosenkilde, Mette, Andersen, Mads Hald, Svane, Inge Marie & Hjortø, Gertrud Malene, Sep 2016, In: Cytotherapy. 18, 9, p. 1187-1196
Research output: Contribution to journal › Journal article › Research › peer-review
Published
PD-L1 peptide co-stimulation increases immunogenicity of a dendritic cell-based cancer vaccine
Munir Ahmad, S., Martinenaite, E., Hansen, M., Junker, N., Borch, T. H., Met, Özcan, Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2 Aug 2016, In: OncoImmunology. 5, 8, e1202391.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cabazitaxel as second-line or third-line therapy in patients with metastatic castration-resistant prostate cancer
Kongsted, P., Svane, Inge Marie, Lindberg, H., Bisbjerg, R., Daugaard, G. & Sengeløv, L., Aug 2016, In: Anti-Cancer Drugs. 27, 7, p. 695-701 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen
Andersen, R., Donia, M., Ellebæk, E., Borch, T. H., Kongsted, P., Iversen, T. Z., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Met, Özcan, Andersen, Mads Hald, Thor Straten, E. P. & Svane, Inge Marie, Aug 2016, In: Clinical Cancer Research. 22, 15, p. 3734-3745 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Safety, immune and clinical responses in metastatic melanoma patients vaccinated with a long peptide derived from indoleamine 2,3-dioxygenase in combination with ipilimumab
Bjørn, J., Iversen, T. Z., Nitschke, N. J., Andersen, Mads Hald & Svane, Inge Marie, Aug 2016, In: Cytotherapy. 18, 8, p. 1043-1055 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Behandlingen af BRAF-muteret metastatisk melanom med BRAF/MEK-inhibitorer bedrer prognosen
Boyles, T. B., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V02160126.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment
Martinenaite, E., Munir Ahmad, S., Hansen, M., Met, Özcan, Westergaard, M. W., Larsen, S. K., Klausen, T. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2016, In: OncoImmunology. 5, 11, 10 p., e1238541.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immuncheckpointantistoffer øger overlevelsen for patienter med metastatisk melanom
Fløe, L. E., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V01160070.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immune monitoring using mRNA-transfected dendritic cells
Borch, T. H., Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Humana Press, Vol. 1428. p. 245-259 15 p. (Methods in Molecular Biology, Vol. 1428).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
Immunological correlates of treatment and response in stage IV malignant melanoma patients treated with Ipilimumab
Bjoern, J., Juul Nitschke, N., Zeeberg Iversen, T., Schmidt, H., Fode, K. & Svane, Inge Marie, 2016, In: OncoImmunology. 5, 4, 10 p., e1100788.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Interferon-α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK2V617F-positive essential thrombocythemia and polycythemia vera
Riley, C. H., Brimnes, M. K., Hansen, M., Jensen, M. K., Hasselbalch, Hans Carl, Kjaer, L., Straten, P. T. & Svane, Inge Marie, 2016, In: European Journal of Haematology. 97, 1, p. 83-92 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Large-scale mRNA transfection of dendritic cells by electroporation in continuous flow systems
Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., 2016, Methods in Molecular Biology. Humana Press, Vol. 1428. p. 151-161 11 p. (Methods in Molecular Biology, Vol. 1428).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
Peptide vaccination against multiple myeloma using peptides derived from anti-apoptotic proteins: a phase I trial
Jørgensen, N. G., Ahmad, S. M., Abildgaard, N., Straten, P. T., Svane, Inge Marie, Andersen, Mads Hald & Knudsen, L. M., 2016, In: Stem Cell Investigation. 3, 5 p., 95.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Predictors of Chemotherapy-Induced Toxicity and Treatment Outcomes in Elderly Versus Younger Patients With Metastatic Castration-Resistant Prostate Cancer
Kongsted, P., Svane, Inge Marie, Lindberg, H. & Sengeløv, L., 2016, In: Clinical Genitourinary Cancer. 14, 6, p. e559-e568
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The controversial role of TNF in melanoma
Donia, M., Kjeldsen, J. W. & Svane, Inge Marie, 2016, In: OncoImmunology. 5, 4, 2 p., e1107699.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
Transfection of tumor-infiltrating T cells with mRNA encoding CXCR2
Idorn, M., thor Straten, E. P., Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Rhoads, R. E. (ed.). Springer, Vol. 1428. p. 261-276 16 p. (Methods in Molecular Biology, Vol. 1428).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
2015
Published
Tumor-infiltrating lymphocytes for the treatment of metastatic cancer
Geukes Foppen, M. H., Donia, M., Svane, Inge Marie & Haanen, J. B. A. G., Dec 2015, In: Molecular Oncology. 9, 10, p. 1918-35 18 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Low-dose prednisolone in first-line docetaxel for patients with metastatic castration-resistant prostate cancer: is there a clinical benefit?
Kongsted, P., Svane, Inge Marie, Lindberg, H., Daugaard, G. & Sengeløv, L., Nov 2015, In: Urologic Oncology: Seminars and Original Investigations. 33, 11, p. 494.e15-20
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05
Frøsig, T. M., Yap, J., Seremet, T., Lyngaa, R., Svane, Inge Marie, Thor Straten, P., Heemskerk, M. H. M., Grotenbreg, G. M. & Hadrup, S. R., Oct 2015, In: Cytometry. Part A. 87, 10, p. 967-75 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4⁺ T- Cells, Which Dampen CD8⁺ T-cell Antitumor Reactivity
Donia, M., Andersen, R., Kjeldsen, J. W., Fagone, P., Munir, S., Nicoletti, F., Andersen, Mads Hald, Thor Straten, P. & Svane, Inge Marie, 15 Sep 2015, In: Cancer Research. 75, 18, p. 3747-59 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers
Dolton, G., Tungatt, K., Lloyd, A., Bianchi, V., Theaker, S. M., Trimby, A., Holland, C. J., Donia, M., Godkin, A. J., Cole, D. K., Straten, P. T., Peakman, M., Svane, Inge Marie & Sewell, A. K., Sep 2015, In: Immunology. 146, 1, p. 11-22 12 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Reorienting the immune system in the treatment of cancer by using anti-PD-1 and anti-PD-L1 antibodies
Borch, T. H., Donia, M., Andersen, Mads Hald & Svane, Inge Marie, Sep 2015, In: Drug Discovery Today. 20, 9, p. 1127-34 8 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Broadening the repertoire of melanoma-associated T-cell epitopes
Frøsig, T. M., Lyngaa, R., Met, Özcan, Larsen, S. K., Donia, M., Svane, Inge Marie, Thor Straten, P. & Hadrup, S. R., May 2015, In: Cancer immunology, immunotherapy : CII. 64, 5, p. 609-20 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Neuroprotective and anti-inflammatory mechanisms are activated early in optic neuritis
Tsakiri, A., Ravanidis, S., Lagoudaki, R., Poulatsidou, K., Svane, Inge Marie, Fredriksen, Jette Lautrup & Grigoriadis, N., May 2015, In: Acta Neurologica Scandinavica. 131, 5, p. 305-12 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Confinement dependent chemotaxis in two-photon polymerized linear migration constructs with highly definable concentration gradients
Hjortø, Gertrud Malene, Olsen, M. H., Svane, Inge Marie & Larsen, N. B., Apr 2015, In: Biomedical Microdevices. 17, 2, p. 1-10 10 p., 30.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
Weber, J. S., D'Angelo, S. P., Minor, D., Hodi, F. S., Gutzmer, R., Neyns, B., Hoeller, C., Khushalani, N. I., Miller, W. H., Lao, C. D., Linette, G. P., Thomas, L., Lorigan, P., Grossmann, K. F., Hassel, J. C., Maio, M., Sznol, M., Ascierto, P. A., Mohr, P., Chmielowski, B. & 8 others, Bryce, A., Svane, Inge Marie, Grob, J., Krackhardt, A. M., Horak, C., Lambert, A., Yang, A. S. & Larkin, J., Apr 2015, In: Lancet Oncology. 16, 4, p. 375-84 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Expansion of circulating CD56^bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α
Riley, C. H., Hansen, M., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., Straten, P. T., Svane, Inge Marie & Jensen, M. K., Mar 2015, In: European Journal of Haematology. 94, 3, p. 227–234 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Antibody Stabilization of Peptide–MHC Multimers Reveals Functional T Cells Bearing Extremely Low-Affinity TCRs
Tungatt, K., Bianchi, V., Crowther, M. D., Powell, W. E., Schauenburg, A. J., Trimby, A., Donia, M., Miles, J. J., Holland, C. J., Cole, D. K., Godkin, A. J., Peakman, M., Straten, P. T., Svane, Inge Marie, Sewell, A. K. & Dolton, G., Jan 2015, In: Journal of immunology (Baltimore, Md. : 1950). 194, 1, p. 463-474 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The Targeting of Indoleamine 2,3 Dioxygenase -Mediated Immune Escape in Cancer
Iversen, T. Z., Andersen, Mads Hald & Svane, Inge Marie, Jan 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 1, p. 19-24 6 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Tryptophan 2,3-dioxygenase (TDO)-reactive T cells differ in their functional characteristics in health and cancer
Hjortsø, M. D., Larsen, S. K., Kongsted, P., Met, Özcan, Frøsig, T. M., Andersen, G. H., Ahmad, S. M., Svane, Inge Marie, Becker, J. C., Straten, P. T. & Andersen, Mads Hald, Jan 2015, In: OncoImmunology. 4, 1, e968480.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Indoleamine 2,3-dioxygenase vaccination
Andersen, Mads Hald & Svane, Inge Marie, 2015, In: OncoImmunology. 4, 1, p. 1-3 3 p., e983770.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma
Andersen, R., Donia, M., Westergaard, M. C. W., Pedersen, M., Hansen, M. & Svane, Inge Marie, 2015, In: Human Vaccines & Immunotherapeutics. 11, 12, p. 2790-5 6 p.
Research output: Contribution to journal › Comment/debate › Research
2014
Published
Successful treatment with Ipilimumab and Interleukin‑2 in two patients with metastatic melanoma and systemic autoimmune disease
Pedersen, M., Andersen, R., Larsen, P. N., Jacobsen, Søren, Thielsen, P., Thor Straten, P. & Svane, Inge Marie, Dec 2014, In: Cancer immunology, immunotherapy : CII. 63, 12, p. 1341-6 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Simplified protocol for clinical-grade tumor-infiltrating lymphocyte manufacturing with use of the Wave bioreactor
Donia, M., Larsen, S. M., Met, Özcan & Svane, Inge Marie, Aug 2014, In: Cytotherapy. 16, 8, p. 1117–1120 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Late development of splenic sarcoidosis-like lesions in a patient with metastatic melanoma and long-lasting clinical response to ipilimumab
Andersen, R., Nørgaard, P. H., Al-Jailawi, M. K. M. & Svane, Inge Marie, 23 Jan 2014, In: OncoImmunology. 3, 8, e954506.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Long-lasting Disease Stabilization in the Absence of Toxicity in Metastatic Lung Cancer Patients Vaccinated with an Epitope Derived from Indoleamine 2,3 Dioxygenase
Iversen, T. Z., Engell-Noerregaard, L., Ellebaek, E., Andersen, R. S., Larsen, S. K., Bjoern, J., Zeyher, C., Gouttefangeas, C., Thomsen, B. M., Holm, B., Thor Straten, P., Mellemgaard, A., Andersen, Mads Hald & Svane, Inge Marie, 1 Jan 2014, In: Clinical Cancer Research. 20, 1, p. 221-232 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Spontaneous presence of FOXO3-specific T cells in cancer patients
Larsen, S. K., Ahmad, S. M., Idorn, M., Met, Özcan, Martinenaite, E., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 1 Jan 2014, In: OncoImmunology. 3, 8, e953411.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway
Ahmad, S. M., Larsen, S. K., Svane, Inge Marie & Andersen, M. H., Jan 2014, In: Leukemia. 28, 1, p. 236-238 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?
Svane, Inge Marie & Verdegaal, E. M., 2014, In: Cancer immunology, immunotherapy : CII. 63, 10, p. 1081-1091 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2013
Published
In-chip fabrication of free-form 3D constructs for directed cell migration analysis
Olsen, M. H., Hjortø, Gertrud Malene, Hansen, M., Met, Özcan, Svane, Inge Marie & Larsen, N. B., 21 Dec 2013, In: Lab On a Chip. 13, 24, p. 4800-4809 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Functional characterization of Foxp3-specific spontaneous immune responses
Larsen, S. K., Munir, S., Woetmann, Anders , Frøsig, T. M., Ødum, Niels, Svane, Inge Marie, Becker, J. C. & Andersen, Mads Hald, Dec 2013, In: Leukemia. 27, 12, p. 2332-40 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients
Munir, S., Andersen, G. H., Met, Özcan, Donia, M., Frøsig, T. M., Larsen, S. K., Klausen, T. W., Svane, Inge Marie & Andersen, Mads Hald, 15 Mar 2013, In: Cancer Research. 73, 6, p. 1764-76 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Analysis of Survivin-Specific T Cells in Breast Cancer Patients Using Human DCs Engineered with Survivin mRNA
Met, Özcan & Svane, Inge Marie, 2013, Synthetic Messenger RNA and Cell Metabolism Modulation. Vol. 969. p. 275-292 18 p. (Methods in Molecular Biology).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy
Hansen, M., Hjortø, Gertrud Malene, Donia, M., Met, Özcan, Larsen, N. B., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2013, In: Vaccine. 31, 4, p. 639-46 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients
Iversen, T. Z., Brimnes, M. K., Nikolajsen, K., Andersen, R. S., Hadrup, S. R., Andersen, M. H., Bastholt, L. & Svane, Inge Marie, 2013, In: OncoImmunology. 2, 2, p. 1-10 10 p., e23288.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
FDG PET scans as evaluation of clinical response to dendritic cell vaccination in patients with malignant melanoma
Engell-Noerregaard, L., Hendel, H. W., Johannesen, H. H., Alslev, L. & Svane, Inge Marie, 2013, In: Cancer Immunology, Immunotherapy. 62, 1, p. 17-25 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Methods to Improve Adoptive T-Cell Therapy for Melanoma: IFN-γ Enhances Anticancer Responses of Cell Products for Infusion
Donia, M., Hansen, M., Sendrup, S. L., Iversen, T. Z., Ellebæk, E., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2013, In: Journal of Investigative Dermatology. 133, 2, p. 545-52 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Silencing of the glucocorticoid-induced leucine zipper improves the immunogenicity of clinical-grade dendritic cells
Cathelin, D., Met, Özcan & Svane, Inge Marie, 2013, In: Cytotherapy. 15, 6, p. 740-749 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4(+) T cells
Munir, S., Andersen, G. H., Svane, Inge Marie & Andersen, Mads Hald, 2013, In: OncoImmunology. 2, 4, 9 p., e23991.
Research output: Contribution to journal › Journal article › Research › peer-review
2012
Published
A promiscuous survivin-derived T-cell epitope restricted to the HLA-A3 super-type alleles
Junker, N., Munir, S., Kvistborg, P., Straten, P. T., Svane, Inge Marie & Andersen, M. H., 2012, In: Journal of Investigative Dermatology. 132, 8, p. 2115-2118 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients
Ellebaek, E., Iversen, T. Z., Junker, N., Donia, M., Engell-Noerregaard, L., Met, Özcan, Hølmich, Lisbet Rosenkrantz, Andersen, R. S., Hadrup, S. R., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2012, In: Journal of Translational Medicine. 10, p. 169
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes
Donia, M., Ellebaek, E., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2012, In: OncoImmunology. 1, 8, p. 1297-1304 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer
Donia, M., Fagone, P., Nicoletti, F., Andersen, R. S., Høgdall, E., Straten, P. T., Andersen, M. H. & Svane, Inge Marie, 2012, In: OncoImmunology. 1, 9, p. 1476-1483 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cellular based cancer vaccines: type 1 polarization of dendritic cells
Hansen, M., Met, O., Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cellular based cancer vaccines: type 1 polarization of dendritic cells
Hansen, M., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Characterization and comparison of "Standard" and "Young" tumor infiltrating lymphocytes for adoptive cell therapy at a Danish Translational Research Institution
Donia, M., Junker, N., Ellebaek, E., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2012, In: Scandinavian Journal of Immunology. 75, 2, p. 157-167 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Characterization of Spontaneous Immune Responses against Long Peptides Derived from Bcl-X(L) in Cancer Patients Using Elispot
Svane, Inge Marie, Straten, P. T., Andersen, M. H., Larsen, S. K. & Hansen, M., 2012, In: Cells. 1, 2, p. 51-60 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Characterization of T-cell responses against IκBα in cancer patients
Munir, S., Frøsig, T. M., Hansen, M., Svane, Inge Marie & Andersen, M. H., 2012, In: OncoImmunology. 1, 8, p. 1290-1296 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comment on "Adoptive T-cell therapy for malignant melanoma patients with TILs obtained by ultrasound-guided needle biopsy" by Gustav J. Ullenhag et al
Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 5, p. 747; author reply 749
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dissection of T-cell antigen specificity in human melanoma
Andersen, R. S., Albæk Thrue, C., Junker, N., Skou, R. B. L., Donia, M., Ellebæk, E., Svane, Inge Marie, Schumacher, T. N., Thor Straten, P. & Hadrup, S. R., 2012, In: Cancer Research. 72, 7, p. 1642-50 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effector and regulatory T cells in patients with acute optic neuritis
Tsakiri, A., Kjærsgaard, E., Grigoriadis, N., Svane, Inge Marie & Frederiksen, J. L., 2012, In: Neuroimmunomodulation. 19, 2, p. 111-20 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Generation of autologous tumor-specific T cells for adoptive transfer based on vaccination, in vitro restimulation and CD3/CD28 dynabead-induced T cell expansion
Brimnes, M. K., Gang, A. O., Donia, M., Thor Straten, P., Svane, Inge Marie & Hadrup, S. R., 2012, In: Cancer Immunology, Immunotherapy. 61, 8, p. 1221-31 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
IFN-γ to improve immunotherapy for melanoma
Donia, M., Svane, Inge Marie, Andersen, M. H., Hansen, M., Straten, P. T., Ellebæk, E., Iversen, T. Z. & SL, S., 2012. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Immunotherapy for metastatic colorectal cancer: Present status and new options
Ellebaek, E., Andersen, M. H., Svane, Inge Marie & Straten, P. T., 2012, In: Scandinavian Journal of Gastroenterology. 47, 3, p. 315-24 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial
Ellebaek, E., Engell-Noerregaard, L., Iversen, T. Z., Moerch Froesig, T., Munir, S., Hadrup, S. R., Andersen, M. H. & Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 10, p. 1791-1804 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase
Munir, S., Larsen, S. K., Iversen, T. Z., Donia, M., Klausen, T. W., Svane, Inge Marie, Straten, P. T. & Andersen, M. H., 2012, In: P L o S One. 7, 4, p. e34568
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tumor associated antigen specific T-cell populations identified in ex vivo expanded TIL cultures
Junker, N., Kvistborg, P., Køllgaard, T., Straten, P. T., Andersen, Mads Hald & Svane, Inge Marie, 2012, In: Cellular Immunology. 273, 1, p. 1-9 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2011
Published
Increase in circulating CD4CD25Foxp3 T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α
Riley, C. H., Morten Krogh, J., Brimnes, M. K., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Bjerrum, O. W., 25 Aug 2011, In: Blood. 118, 8, p. 2170-2173 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip
Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., Apr 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., Buchwald, C. V., Andersen, E., Straten, P. T., Svane, Inge Marie & Andersen, Mads Hald, 24 Mar 2011, In: Cytotherapy. 13, 7, p. 822-34
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2
Sørensen, R. B., Køllgaard, T., Andersen, R. S., van den Berg, J. H., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 15 Mar 2011, In: Cancer Research. 71, 6, p. 2038-44 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators
Sørensen, R. B., Hadrup, S. R., Svane, Inge Marie, Hjortsø, M. C., Thor Straten, P., Andersen, Mads Hald, Hjortsø, M. C. & Andersen, Mads Hald, 17 Feb 2011, In: Blood. 117, 7, p. 2200-10 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cell culture plastics with immobilized interleukin-4 for monocyte differentiation
Hansen, M., Hjortø, Gertrud Malene, Met, Özcan, Jakobsen, M. H., Svane, Inge Marie & Larsen, N. B., Feb 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer
Met, Özcan, Balslev, E., Flyger, H. & Svane, Inge Marie, 1 Jan 2011, In: Breast Cancer Research and Treatment. 125, 2, p. 395-406 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., von Buchwald, Christian, Andersen, E., Straten, P. T. & Svane, Inge Marie, 2011, In: Cytotherapy. 13, 7, p. 822-34 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cell culture plastics with immobilized interleukin-4 for monocyte differentiation
Hansen, M., Hjortø, Gertrud Malene, Met, Ö., Jakobsen, M. H., Svane, Inge Marie & Larsen, N., 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Changes in peripheral blood level of regulatory T cells in patients with malignant melanoma during treatment with dendritic cell vaccination and low-dose IL-2
Bjoern, J., Brimnes, M. K., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2011, In: Scandinavian Journal of Immunology. 73, 3, p. 222-33 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Characterization of ex vivo expanded tumor infiltrating lymphocytes from patients with malignant melanoma for clinical application
Junker, N., Thor Straten, P., Andersen, Mads Hald & Svane, Inge Marie, 2011, In: Journal of Skin Cancer. 2011, 574695, 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip
Selmeczi, D., Hansen, T., Met, Ö., Svane, Inge Marie & Larsen, N., 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors
Andersen, R. S., Sørensen, R. B., Ritter, C., Svane, Inge Marie, Becker, J. C., thor Straten, P. & Andersen, Mads Hald, 2011, In: Cancer Immunology, Immunotherapy. 60, 2, p. 227-34 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Increase in circulating CD4⁺CD25⁺Foxp3⁺ T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α
Riley, C. H., Jensen, M. K., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., Straten, P. T. & Svane, Inge Marie, 2011, In: Blood. 118, 8, p. 2170-3 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Wildtype p53-specific Antibody and T-Cell Responses in Cancer Patients
Pedersen, Anders Elm, Stryhn, A., Justesen, S., Harndahl, M., Rasmussen, S., Donskov, F., Claesson, Mogens Helweg, Pedersen, J. W., Wandall, Hans H., Svane, Inge Marie & Buus, Søren, 2011, In: Journal of Immunotherapy. 34, 9, p. 629-40 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2010
Published
Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR⁻/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma
Brimnes, M. K., Vangsted, A. J., Knudsen, L. M., Gimsing, P., Gang, A. O., Johnsen, H. & Svane, Inge Marie, 1 Dec 2010, In: Scandinavian Journal of Immunology. 72, 6, p. 540-7 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial
Schmidt, H., Brown, J., Mouritzen, U., Selby, P., Fode, K., Svane, Inge Marie, Cook, G. P., Mollerup, D. H. & Geertsen, P. F., 1 Nov 2010, In: Clinical Cancer Research. 16, 21, p. 5312-9 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial
Trepiakas, R., Berntsen, A., Hadrup, S. R., Bjørn, J., Geertsen, P. F., Straten, P. T., Andersen, Mads Hald, Pedersen, Anders Elm, Soleimani, A., Lorentzen, T., Johansen, Julia Sidenius & Svane, Inge Marie, 1 Oct 2010, In: Cytotherapy. 12, 6, p. 721-34 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Increased immunopotency of monocyte derived dendritic cells from patients with optic neuritis is inhibited in vitro by simvastatin
Tsakiri, A., Tsiantoulas, D., Fredriksen, Jette Lautrup & Svane, Inge Marie, 1 Feb 2010, In: Experimental Neurology. 221, 2, p. 320-8 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Therapeutic cancer vaccines in combination with conventional therapy
Andersen, Mads Hald, Junker, N., Ellebaek, E., Svane, Inge Marie, Thor Straten, P. & Andersen, Mads Hald, 1 Jan 2010, In: Journal of Biomedicine and Biotechnology. 2010, p. 237623
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Combined Treatment with Dendritic Cell Vaccine and Low-Dose Cyclophosphamide in Patients with Malignant Melanoma
Engell-Noerregaard, L., Ellebaek, E., Buch-Hansen, T. Z., Nikolajsen, K., Straten, P. T., Andersen, Mads Hald, Svane, Inge Marie & Andersen, Mads Hald, 2010, In: Journal of Immunotherapy. 33, 8, p. 876-877 2 p.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Dendritic Cells Transfected with mRNA for p53, Survivin and hTERT as Treatment for Patients With Malignant Melanoma or Breast Cancer-A Phase I Study
Engell-Noerregaard, L., Hansen, T. H., Met, Ö., Andersen, Mads Hald, Svane, Inge Marie & Andersen, Mads Hald, 2010, In: Journal of Immunotherapy. 33, 8, p. 876 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Increase of Circulating CD4(+)CD25(high)Foxp3(+) Regulatory T Cells in Patients With Metastatic Renal Cell Carcinoma During Treatment With Dendritic Cell Vaccination and Low-Dose Interleukin-2
Berntsen, A., Brimnes, M. K., Straten, P. T., Svane, Inge Marie, Berntsen, A., Brimnes, M. K., Straten, P. T. & Svane, Inge Marie, 2010, In: Journal of Immunotherapy. 33, 4, p. 425-434 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Increase of circulating CD4+CD25highFoxp3+ regulatory T cells in patients with metastatic renal cell carcinoma during treatment with dendritic cell vaccination and low-dose interleukin-2
Berntsen, A., Brimnes, M. K., thor Straten, P. & Svane, Inge Marie, 2010, In: Journal of Immunotherapy. 33, 4, p. 425-34 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR⿻/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma
Brimnes, M. K., Vangsted, Annette Juul, Knudsen, L. M., Gimsing, P., Gang, Uffe Jakob Ortved, Johnsen, H. & Svane, Inge Marie, 2010, In: Scandinavian Journal of Immunology. 72, 6, p. 540-7
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Therapeutic Vaccination Targeting Indoleamine-2, 3 Dioxygenase (IDO) Using a IDO Derived Class I Restricted Peptide in Combination with Aldara and Montanide for Patients With Locally Advanced or Metastatic Non Small-Cell Lung Cancer. A First-in-man Phase I Trial
Buch-Hansen, T. Z., Sørensen, R. B., Mellemgaard, A., Straten, P. T., Andersen, Mads Hald, Svane, Inge Marie & Andersen, Mads Hald, 2010, In: Journal of Immunotherapy. 33, 8, p. 919-920 2 p.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Therapeutic cancer vaccines
Larsen, S. K., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 2010, In: Current Cancer Therapy Reviews. 6, 2, p. 163-174
Research output: Contribution to journal › Journal article › Research › peer-review
2009
Published
Addition of interferon-alpha to a standard maturation cocktail induces CD38 up-regulation and increases dendritic cell function
Trepiakas, R., Pedersen, Anders Elm, Met, Özcan & Svane, Inge Marie, 2009, In: Vaccine. 27, 16, p. 2213-9 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
CD8 T-cell responses against cyclin B1 in breast cancer patients with tumors overexpressing p53
Sørensen, R. B., Andersen, R. S., Svane, Inge Marie, Engell-Noerregaard, L., Hadrup, S. R., Balslev, E., Andersen, Mads Hald & thor Straten, P., 2009, In: Clinical Cancer Research. 15, 5, p. 1543-9 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Identification of heme oxygenase-1-specific regulatory CD8+ T cells in cancer patients
Andersen, Mads Hald, Sørensen, R. B., Brimnes, M. K., Svane, Inge Marie, Becker, J. C. & thor Straten, P., 2009, In: Journal of Clinical Investigation. 119, 8, p. 2245-56 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immune responses in patients with metastatic renal cell carcinoma treated with dendritic cells pulsed with tumor lysate
Soleimani, A., Berntsen, A., Svane, Inge Marie & Pedersen, Anders Elm, 2009, In: Scandinavian Journal of Immunology. 70, 5, p. 481-9 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Induction of novel CD8+ T-cell responses during chronic untreated HIV-1 infection by immunization with subdominant cytotoxic T-lymphocyte epitopes
Kloverpris, H., Karlsson, I., Bonde, J., Thorn, M., Vinner, L., Pedersen, A., Hentze, J., Andresen, B., Svane, I., Gerstoft, J., Kronborg, G., Fomsgaard, A., Kloverpris, H., Karlsson, I., Bonde, J., Thorn, M., Vinner, L., Pedersen, A. E., Hentze, J. L., Andresen, B. S. & 4 others, Svane, I. M., Gerstoft, J., Kronborg, Gitte & Fomsgaard, A., 2009, In: AIDS. 23, 11, p. 1329-40 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: assessment of correlation between clinical response and vaccine parameters
Engell-Noerregaard, L., Hansen, T. H., Andersen, Mads Hald, Thor Straten, P. & Svane, Inge Marie, 2009, In: Cancer Immunology, Immunotherapy. 58, 1, p. 1-14 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The 1170 A-P single-nucleotide polymorphism (SNP) in the Her-2/neu protein (HER2) as a minor histocompatibility antigen (mHag)
Wenandy, L., Kollgaard, T., Letsch, A., Andersen, R. S., Stather, D., Seremet, T., Svane, Inge Marie, Vindeløv, L., Andersen, M. H. & thor Straten, P., 2009, In: Leukemia. 23, 10, p. 1926-9 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase
Sørensen, R. B., Berge-Hansen, L., Junker, N., Hansen, C. A., Hadrup, S. R., Schumacher, T. N. M., Svane, Inge Marie, Becker, J. C., thor Straten, P. & Andersen, Mads Hald, 2009, In: PLoS ONE. 4, 9, p. e6910
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The immunodominant HLA-A2-restricted MART-1 epitope is not presented on the surface of many melanoma cell lines
Sørensen, R. B., Junker, N., Kirkin, A., Voigt, H., Svane, Inge Marie, Becker, J. C., thor Straten, P. & Andersen, Mads Hald, 2009, In: Cancer Immunology, Immunotherapy. 58, 5, p. 665-75 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2008
Published
Studies on mRNA electroporation of immature and mature dendritic cells: effects on their immunogenic potential
Met, Özcan, Eriksen, J. & Svane, Inge Marie, Oct 2008, In: Molecular Biotechnology. 40, 2, p. 151-60 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cancer treatment: the combination of vaccination with other therapies
Andersen, M. H., Sorensen, R. B., Schrama, D., Becker, J. C., Straten, P. T. & Svane, Inge Marie, 2008, In: Cancer Immunology, Immunotherapy. 57, 11, p. 1735-1743 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Characterization of a single peptide derived from cytochrome P4501B1 that elicits spontaneous human leukocyte antigen (HLA)-A1 as well as HLA-B35 restricted CD8 T-cell responses in cancer patients
Kvistborg, P., Hadrup, S. R., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2008, In: Human Immunology. 69, 4-5, p. 266-272 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immunogenicity of the hTERT540-548 peptide in cancer
Wenandy, L., Sorensen, R. B., Sengelov, L., Straten, P. T., Andersen, M. H. & Svane, Inge Marie, 2008, In: Clinical Cancer Research. 14, 1, p. 4-7 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
RhoC a new target for therapeutic vaccination against metastatic cancer
Wenandy, L., Sorensen, R. B., Straten, P. T., Andersen, M. H. & Svane, Inge Marie, 2008, In: Cancer Immunology, Immunotherapy. 57, 12, p. 1871-1878 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Studies on mRNA electroporation of immature and mature dendritic cells: Effects on their immunogenic potential
Met, O., Eriksen, J. & Svane, Inge Marie, 2008, In: Journal of Molecular Microbiology and Biotechnology. 40, 2, p. 151-160 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2005
Published
Immunogenicity of Bcl-2 in patients with cancer
Andersen, M. H., Svane, Inge Marie, Kvistborg, P., Nielsen, O. J., Balslev, E., Reker, S., Becker, J. C. & Straten, P. T., 15 Jan 2005, In: Blood. 105, 2, p. 728-34 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2003
Published
Clinical application of dendritic cells in cancer vaccination therapy
Svane, Inge Marie, Soot, M. L., Buus, Søren & Johnsen, H. E., 2003, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 111, 7-8, p. 818-34 16 p.
Research output: Contribution to journal › Journal article › Research › peer-review

ID: 4054758

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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published
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T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
Research output: Contribution to journal › Journal article › Research › peer-review
Published
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Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
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Published

Inge Marie Svane

Member of:

Clinical Oncology