Inge Marie Svane

Inge Marie Svane

Clinical Professor

Member of:

  • Clinical Oncology


  1. 2003
  2. Published

    Clinical application of dendritic cells in cancer vaccination therapy

    Svane, Inge Marie, Soot, M. L., Buus, Søren & Johnsen, H. E., 2003, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 111, 7-8, p. 818-34 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2005
  4. Published

    Immunogenicity of Bcl-2 in patients with cancer

    Andersen, M. H., Svane, Inge Marie, Kvistborg, P., Nielsen, O. J., Balslev, E., Reker, S., Becker, J. C. & Straten, P. T., 15 Jan 2005, In: Blood. 105, 2, p. 728-34 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2008
  6. Published

    Cancer treatment: the combination of vaccination with other therapies

    Andersen, M. H., Sorensen, R. B., Schrama, D., Becker, J. C., Straten, P. T. & Svane, Inge Marie, 2008, In: Cancer Immunology, Immunotherapy. 57, 11, p. 1735-1743 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Characterization of a single peptide derived from cytochrome P4501B1 that elicits spontaneous human leukocyte antigen (HLA)-A1 as well as HLA-B35 restricted CD8 T-cell responses in cancer patients

    Kvistborg, P., Hadrup, S. R., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2008, In: Human Immunology. 69, 4-5, p. 266-272 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Immunogenicity of the hTERT540-548 peptide in cancer

    Wenandy, L., Sorensen, R. B., Sengelov, L., Straten, P. T., Andersen, M. H. & Svane, Inge Marie, 2008, In: Clinical Cancer Research. 14, 1, p. 4-7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    RhoC a new target for therapeutic vaccination against metastatic cancer

    Wenandy, L., Sorensen, R. B., Straten, P. T., Andersen, M. H. & Svane, Inge Marie, 2008, In: Cancer Immunology, Immunotherapy. 57, 12, p. 1871-1878 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Studies on mRNA electroporation of immature and mature dendritic cells: Effects on their immunogenic potential

    Met, O., Eriksen, J. & Svane, Inge Marie, 2008, In: Journal of Molecular Microbiology and Biotechnology. 40, 2, p. 151-160 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Studies on mRNA electroporation of immature and mature dendritic cells: effects on their immunogenic potential

    Met, Özcan, Eriksen, J. & Svane, Inge Marie, Oct 2008, In: Molecular Biotechnology. 40, 2, p. 151-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2009
  13. Published

    Addition of interferon-alpha to a standard maturation cocktail induces CD38 up-regulation and increases dendritic cell function

    Trepiakas, R., Pedersen, Anders Elm, Met, Özcan & Svane, Inge Marie, 2009, In: Vaccine. 27, 16, p. 2213-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    CD8 T-cell responses against cyclin B1 in breast cancer patients with tumors overexpressing p53

    Sørensen, R. B., Andersen, R. S., Svane, Inge Marie, Engell-Noerregaard, L., Hadrup, S. R., Balslev, E., Andersen, Mads Hald & thor Straten, P., 2009, In: Clinical Cancer Research. 15, 5, p. 1543-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Identification of heme oxygenase-1-specific regulatory CD8+ T cells in cancer patients

    Andersen, Mads Hald, Sørensen, R. B., Brimnes, M. K., Svane, Inge Marie, Becker, J. C. & thor Straten, P., 2009, In: Journal of Clinical Investigation. 119, 8, p. 2245-56 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Immune responses in patients with metastatic renal cell carcinoma treated with dendritic cells pulsed with tumor lysate

    Soleimani, A., Berntsen, A., Svane, Inge Marie & Pedersen, Anders Elm, 2009, In: Scandinavian Journal of Immunology. 70, 5, p. 481-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Induction of novel CD8+ T-cell responses during chronic untreated HIV-1 infection by immunization with subdominant cytotoxic T-lymphocyte epitopes

    Kloverpris, H., Karlsson, I., Bonde, J., Thorn, M., Vinner, L., Pedersen, A., Hentze, J., Andresen, B., Svane, I., Gerstoft, J., Kronborg, G., Fomsgaard, A., Kloverpris, H., Karlsson, I., Bonde, J., Thorn, M., Vinner, L., Pedersen, A. E., Hentze, J. L., Andresen, B. S. & 4 others, Svane, I. M., Gerstoft, J., Kronborg, Gitte & Fomsgaard, A., 2009, In: AIDS. 23, 11, p. 1329-40 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: assessment of correlation between clinical response and vaccine parameters

    Engell-Noerregaard, L., Hansen, T. H., Andersen, Mads Hald, Thor Straten, P. & Svane, Inge Marie, 2009, In: Cancer Immunology, Immunotherapy. 58, 1, p. 1-14 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The 1170 A-P single-nucleotide polymorphism (SNP) in the Her-2/neu protein (HER2) as a minor histocompatibility antigen (mHag)

    Wenandy, L., Kollgaard, T., Letsch, A., Andersen, R. S., Stather, D., Seremet, T., Svane, Inge Marie, Vindeløv, L., Andersen, M. H. & thor Straten, P., 2009, In: Leukemia. 23, 10, p. 1926-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase

    Sørensen, R. B., Berge-Hansen, L., Junker, N., Hansen, C. A., Hadrup, S. R., Schumacher, T. N. M., Svane, Inge Marie, Becker, J. C., thor Straten, P. & Andersen, Mads Hald, 2009, In: PLoS ONE. 4, 9, p. e6910

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The immunodominant HLA-A2-restricted MART-1 epitope is not presented on the surface of many melanoma cell lines

    Sørensen, R. B., Junker, N., Kirkin, A., Voigt, H., Svane, Inge Marie, Becker, J. C., thor Straten, P. & Andersen, Mads Hald, 2009, In: Cancer Immunology, Immunotherapy. 58, 5, p. 665-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2010
  23. Published

    Combined Treatment with Dendritic Cell Vaccine and Low-Dose Cyclophosphamide in Patients with Malignant Melanoma

    Engell-Noerregaard, L., Ellebaek, E., Buch-Hansen, T. Z., Nikolajsen, K., Straten, P. T., Andersen, Mads Hald, Svane, Inge Marie & Andersen, Mads Hald, 2010, In: Journal of Immunotherapy. 33, 8, p. 876-877 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  24. Published

    Dendritic Cells Transfected with mRNA for p53, Survivin and hTERT as Treatment for Patients With Malignant Melanoma or Breast Cancer-A Phase I Study

    Engell-Noerregaard, L., Hansen, T. H., Met, Ö., Andersen, Mads Hald, Svane, Inge Marie & Andersen, Mads Hald, 2010, In: Journal of Immunotherapy. 33, 8, p. 876 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  25. Published

    Increase of Circulating CD4(+)CD25(high)Foxp3(+) Regulatory T Cells in Patients With Metastatic Renal Cell Carcinoma During Treatment With Dendritic Cell Vaccination and Low-Dose Interleukin-2

    Berntsen, A., Brimnes, M. K., Straten, P. T., Svane, Inge Marie, Berntsen, A., Brimnes, M. K., Straten, P. T. & Svane, Inge Marie, 2010, In: Journal of Immunotherapy. 33, 4, p. 425-434 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Increase of circulating CD4+CD25highFoxp3+ regulatory T cells in patients with metastatic renal cell carcinoma during treatment with dendritic cell vaccination and low-dose interleukin-2

    Berntsen, A., Brimnes, M. K., thor Straten, P. & Svane, Inge Marie, 2010, In: Journal of Immunotherapy. 33, 4, p. 425-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR⿻/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma

    Brimnes, M. K., Vangsted, Annette Juul, Knudsen, L. M., Gimsing, P., Gang, Uffe Jakob Ortved, Johnsen, H. & Svane, Inge Marie, 2010, In: Scandinavian Journal of Immunology. 72, 6, p. 540-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Therapeutic Vaccination Targeting Indoleamine-2, 3 Dioxygenase (IDO) Using a IDO Derived Class I Restricted Peptide in Combination with Aldara and Montanide for Patients With Locally Advanced or Metastatic Non Small-Cell Lung Cancer. A First-in-man Phase I Trial

    Buch-Hansen, T. Z., Sørensen, R. B., Mellemgaard, A., Straten, P. T., Andersen, Mads Hald, Svane, Inge Marie & Andersen, Mads Hald, 2010, In: Journal of Immunotherapy. 33, 8, p. 919-920 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  29. Published

    Therapeutic cancer vaccines

    Larsen, S. K., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 2010, In: Current Cancer Therapy Reviews. 6, 2, p. 163-174

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Therapeutic cancer vaccines in combination with conventional therapy

    Andersen, Mads Hald, Junker, N., Ellebaek, E., Svane, Inge Marie, Thor Straten, P. & Andersen, Mads Hald, 1 Jan 2010, In: Journal of Biomedicine and Biotechnology. 2010, p. 237623

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Increased immunopotency of monocyte derived dendritic cells from patients with optic neuritis is inhibited in vitro by simvastatin

    Tsakiri, A., Tsiantoulas, D., Fredriksen, Jette Lautrup & Svane, Inge Marie, 1 Feb 2010, In: Experimental Neurology. 221, 2, p. 320-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial

    Trepiakas, R., Berntsen, A., Hadrup, S. R., Bjørn, J., Geertsen, P. F., Straten, P. T., Andersen, Mads Hald, Pedersen, Anders Elm, Soleimani, A., Lorentzen, T., Johansen, Julia Sidenius & Svane, Inge Marie, 1 Oct 2010, In: Cytotherapy. 12, 6, p. 721-34 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial

    Schmidt, H., Brown, J., Mouritzen, U., Selby, P., Fode, K., Svane, Inge Marie, Cook, G. P., Mollerup, D. H. & Geertsen, P. F., 1 Nov 2010, In: Clinical Cancer Research. 16, 21, p. 5312-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR⁻/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma

    Brimnes, M. K., Vangsted, A. J., Knudsen, L. M., Gimsing, P., Gang, A. O., Johnsen, H. & Svane, Inge Marie, 1 Dec 2010, In: Scandinavian Journal of Immunology. 72, 6, p. 540-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2011
  36. Published

    Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer

    Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., von Buchwald, Christian, Andersen, E., Straten, P. T. & Svane, Inge Marie, 2011, In: Cytotherapy. 13, 7, p. 822-34 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cell culture plastics with immobilized interleukin-4 for monocyte differentiation

    Hansen, M., Hjortø, Gertrud Malene, Met, Ö., Jakobsen, M. H., Svane, Inge Marie & Larsen, N., 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Changes in peripheral blood level of regulatory T cells in patients with malignant melanoma during treatment with dendritic cell vaccination and low-dose IL-2

    Bjoern, J., Brimnes, M. K., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2011, In: Scandinavian Journal of Immunology. 73, 3, p. 222-33 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Characterization of ex vivo expanded tumor infiltrating lymphocytes from patients with malignant melanoma for clinical application

    Junker, N., Thor Straten, P., Andersen, Mads Hald & Svane, Inge Marie, 2011, In: Journal of Skin Cancer. 2011, 574695, 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip

    Selmeczi, D., Hansen, T., Met, Ö., Svane, Inge Marie & Larsen, N., 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors

    Andersen, R. S., Sørensen, R. B., Ritter, C., Svane, Inge Marie, Becker, J. C., thor Straten, P. & Andersen, Mads Hald, 2011, In: Cancer Immunology, Immunotherapy. 60, 2, p. 227-34 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Increase in circulating CD4⁺CD25⁺Foxp3⁺ T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α

    Riley, C. H., Jensen, M. K., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., Straten, P. T. & Svane, Inge Marie, 2011, In: Blood. 118, 8, p. 2170-3 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Wildtype p53-specific Antibody and T-Cell Responses in Cancer Patients

    Pedersen, Anders Elm, Stryhn, A., Justesen, S., Harndahl, M., Rasmussen, S., Donskov, F., Claesson, Mogens Helweg, Pedersen, J. W., Wandall, Hans H., Svane, Inge Marie & Buus, Søren, 2011, In: Journal of Immunotherapy. 34, 9, p. 629-40 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer

    Met, Özcan, Balslev, E., Flyger, H. & Svane, Inge Marie, 1 Jan 2011, In: Breast Cancer Research and Treatment. 125, 2, p. 395-406 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Cell culture plastics with immobilized interleukin-4 for monocyte differentiation

    Hansen, M., Hjortø, Gertrud Malene, Met, Özcan, Jakobsen, M. H., Svane, Inge Marie & Larsen, N. B., Feb 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators

    Sørensen, R. B., Hadrup, S. R., Svane, Inge Marie, Hjortsø, M. C., Thor Straten, P., Andersen, Mads Hald, Hjortsø, M. C. & Andersen, Mads Hald, 17 Feb 2011, In: Blood. 117, 7, p. 2200-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2

    Sørensen, R. B., Køllgaard, T., Andersen, R. S., van den Berg, J. H., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 15 Mar 2011, In: Cancer Research. 71, 6, p. 2038-44 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer

    Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., Buchwald, C. V., Andersen, E., Straten, P. T., Svane, Inge Marie & Andersen, Mads Hald, 24 Mar 2011, In: Cytotherapy. 13, 7, p. 822-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip

    Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., Apr 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Increase in circulating CD4CD25Foxp3 T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α

    Riley, C. H., Morten Krogh, J., Brimnes, M. K., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Bjerrum, O. W., 25 Aug 2011, In: Blood. 118, 8, p. 2170-2173 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2012
  52. Published

    A promiscuous survivin-derived T-cell epitope restricted to the HLA-A3 super-type alleles

    Junker, N., Munir, S., Kvistborg, P., Straten, P. T., Svane, Inge Marie & Andersen, M. H., 2012, In: Journal of Investigative Dermatology. 132, 8, p. 2115-2118 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

    Ellebaek, E., Iversen, T. Z., Junker, N., Donia, M., Engell-Noerregaard, L., Met, Özcan, Hølmich, Lisbet Rosenkrantz, Andersen, R. S., Hadrup, S. R., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2012, In: Journal of Translational Medicine. 10, p. 169

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes

    Donia, M., Ellebaek, E., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2012, In: OncoImmunology. 1, 8, p. 1297-1304 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer

    Donia, M., Fagone, P., Nicoletti, F., Andersen, R. S., Høgdall, E., Straten, P. T., Andersen, M. H. & Svane, Inge Marie, 2012, In: OncoImmunology. 1, 9, p. 1476-1483 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Cellular based cancer vaccines: type 1 polarization of dendritic cells

    Hansen, M., Met, O., Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Cellular based cancer vaccines: type 1 polarization of dendritic cells

    Hansen, M., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Characterization and comparison of "Standard" and "Young" tumor infiltrating lymphocytes for adoptive cell therapy at a Danish Translational Research Institution

    Donia, M., Junker, N., Ellebaek, E., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2012, In: Scandinavian Journal of Immunology. 75, 2, p. 157-167 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Characterization of Spontaneous Immune Responses against Long Peptides Derived from Bcl-X(L) in Cancer Patients Using Elispot

    Svane, Inge Marie, Straten, P. T., Andersen, M. H., Larsen, S. K. & Hansen, M., 2012, In: Cells. 1, 2, p. 51-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Characterization of T-cell responses against IκBα in cancer patients

    Munir, S., Frøsig, T. M., Hansen, M., Svane, Inge Marie & Andersen, M. H., 2012, In: OncoImmunology. 1, 8, p. 1290-1296 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Comment on "Adoptive T-cell therapy for malignant melanoma patients with TILs obtained by ultrasound-guided needle biopsy" by Gustav J. Ullenhag et al

    Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 5, p. 747; author reply 749

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Dissection of T-cell antigen specificity in human melanoma

    Andersen, R. S., Albæk Thrue, C., Junker, N., Skou, R. B. L., Donia, M., Ellebæk, E., Svane, Inge Marie, Schumacher, T. N., Thor Straten, P. & Hadrup, S. R., 2012, In: Cancer Research. 72, 7, p. 1642-50 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Effector and regulatory T cells in patients with acute optic neuritis

    Tsakiri, A., Kjærsgaard, E., Grigoriadis, N., Svane, Inge Marie & Frederiksen, J. L., 2012, In: Neuroimmunomodulation. 19, 2, p. 111-20 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Generation of autologous tumor-specific T cells for adoptive transfer based on vaccination, in vitro restimulation and CD3/CD28 dynabead-induced T cell expansion

    Brimnes, M. K., Gang, A. O., Donia, M., Thor Straten, P., Svane, Inge Marie & Hadrup, S. R., 2012, In: Cancer Immunology, Immunotherapy. 61, 8, p. 1221-31 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    IFN-γ to improve immunotherapy for melanoma

    Donia, M., Svane, Inge Marie, Andersen, M. H., Hansen, M., Straten, P. T., Ellebæk, E., Iversen, T. Z. & SL, S., 2012. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  66. Published

    Immunotherapy for metastatic colorectal cancer: Present status and new options

    Ellebaek, E., Andersen, M. H., Svane, Inge Marie & Straten, P. T., 2012, In: Scandinavian Journal of Gastroenterology. 47, 3, p. 315-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial

    Ellebaek, E., Engell-Noerregaard, L., Iversen, T. Z., Moerch Froesig, T., Munir, S., Hadrup, S. R., Andersen, M. H. & Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 10, p. 1791-1804 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase

    Munir, S., Larsen, S. K., Iversen, T. Z., Donia, M., Klausen, T. W., Svane, Inge Marie, Straten, P. T. & Andersen, M. H., 2012, In: P L o S One. 7, 4, p. e34568

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Tumor associated antigen specific T-cell populations identified in ex vivo expanded TIL cultures

    Junker, N., Kvistborg, P., Køllgaard, T., Straten, P. T., Andersen, Mads Hald & Svane, Inge Marie, 2012, In: Cellular Immunology. 273, 1, p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. 2013
  71. Published

    Analysis of Survivin-Specific T Cells in Breast Cancer Patients Using Human DCs Engineered with Survivin mRNA

    Met, Özcan & Svane, Inge Marie, 2013, Synthetic Messenger RNA and Cell Metabolism Modulation. Vol. 969. p. 275-292 18 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  72. Published

    Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy

    Hansen, M., Hjortø, Gertrud Malene, Donia, M., Met, Özcan, Larsen, N. B., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2013, In: Vaccine. 31, 4, p. 639-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients

    Iversen, T. Z., Brimnes, M. K., Nikolajsen, K., Andersen, R. S., Hadrup, S. R., Andersen, M. H., Bastholt, L. & Svane, Inge Marie, 2013, In: OncoImmunology. 2, 2, p. 1-10 10 p., e23288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    FDG PET scans as evaluation of clinical response to dendritic cell vaccination in patients with malignant melanoma

    Engell-Noerregaard, L., Hendel, H. W., Johannesen, H. H., Alslev, L. & Svane, Inge Marie, 2013, In: Cancer Immunology, Immunotherapy. 62, 1, p. 17-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Methods to Improve Adoptive T-Cell Therapy for Melanoma: IFN-γ Enhances Anticancer Responses of Cell Products for Infusion

    Donia, M., Hansen, M., Sendrup, S. L., Iversen, T. Z., Ellebæk, E., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2013, In: Journal of Investigative Dermatology. 133, 2, p. 545-52 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Silencing of the glucocorticoid-induced leucine zipper improves the immunogenicity of clinical-grade dendritic cells

    Cathelin, D., Met, Özcan & Svane, Inge Marie, 2013, In: Cytotherapy. 15, 6, p. 740-749 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4(+) T cells

    Munir, S., Andersen, G. H., Svane, Inge Marie & Andersen, Mads Hald, 2013, In: OncoImmunology. 2, 4, 9 p., e23991.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients

    Munir, S., Andersen, G. H., Met, Özcan, Donia, M., Frøsig, T. M., Larsen, S. K., Klausen, T. W., Svane, Inge Marie & Andersen, Mads Hald, 15 Mar 2013, In: Cancer Research. 73, 6, p. 1764-76 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Functional characterization of Foxp3-specific spontaneous immune responses

    Larsen, S. K., Munir, S., Woetmann, Anders , Frøsig, T. M., Ødum, Niels, Svane, Inge Marie, Becker, J. C. & Andersen, Mads Hald, Dec 2013, In: Leukemia. 27, 12, p. 2332-40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    In-chip fabrication of free-form 3D constructs for directed cell migration analysis

    Olsen, M. H., Hjortø, Gertrud Malene, Hansen, M., Met, Özcan, Svane, Inge Marie & Larsen, N. B., 21 Dec 2013, In: Lab On a Chip. 13, 24, p. 4800-4809 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. 2014
  82. Published

    Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?

    Svane, Inge Marie & Verdegaal, E. M., 2014, In: Cancer immunology, immunotherapy : CII. 63, 10, p. 1081-1091 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway

    Ahmad, S. M., Larsen, S. K., Svane, Inge Marie & Andersen, M. H., Jan 2014, In: Leukemia. 28, 1, p. 236-238 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Long-lasting Disease Stabilization in the Absence of Toxicity in Metastatic Lung Cancer Patients Vaccinated with an Epitope Derived from Indoleamine 2,3 Dioxygenase

    Iversen, T. Z., Engell-Noerregaard, L., Ellebaek, E., Andersen, R. S., Larsen, S. K., Bjoern, J., Zeyher, C., Gouttefangeas, C., Thomsen, B. M., Holm, B., Thor Straten, P., Mellemgaard, A., Andersen, Mads Hald & Svane, Inge Marie, 1 Jan 2014, In: Clinical Cancer Research. 20, 1, p. 221-232 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Spontaneous presence of FOXO3-specific T cells in cancer patients

    Larsen, S. K., Ahmad, S. M., Idorn, M., Met, Özcan, Martinenaite, E., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 1 Jan 2014, In: OncoImmunology. 3, 8, e953411.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Late development of splenic sarcoidosis-like lesions in a patient with metastatic melanoma and long-lasting clinical response to ipilimumab

    Andersen, R., Nørgaard, P. H., Al-Jailawi, M. K. M. & Svane, Inge Marie, 23 Jan 2014, In: OncoImmunology. 3, 8, e954506.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Simplified protocol for clinical-grade tumor-infiltrating lymphocyte manufacturing with use of the Wave bioreactor

    Donia, M., Larsen, S. M., Met, Özcan & Svane, Inge Marie, Aug 2014, In: Cytotherapy. 16, 8, p. 1117–1120 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Successful treatment with Ipilimumab and Interleukin‑2 in two patients with metastatic melanoma and systemic autoimmune disease

    Pedersen, M., Andersen, R., Larsen, P. N., Jacobsen, Søren, Thielsen, P., Thor Straten, P. & Svane, Inge Marie, Dec 2014, In: Cancer immunology, immunotherapy : CII. 63, 12, p. 1341-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. 2015
  90. Published

    Indoleamine 2,3-dioxygenase vaccination

    Andersen, Mads Hald & Svane, Inge Marie, 2015, In: OncoImmunology. 4, 1, p. 1-3 3 p., e983770.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma

    Andersen, R., Donia, M., Westergaard, M. C. W., Pedersen, M., Hansen, M. & Svane, Inge Marie, 2015, In: Human Vaccines & Immunotherapeutics. 11, 12, p. 2790-5 6 p.

    Research output: Contribution to journalComment/debateResearch

  92. Published

    Antibody Stabilization of Peptide–MHC Multimers Reveals Functional T Cells Bearing Extremely Low-Affinity TCRs

    Tungatt, K., Bianchi, V., Crowther, M. D., Powell, W. E., Schauenburg, A. J., Trimby, A., Donia, M., Miles, J. J., Holland, C. J., Cole, D. K., Godkin, A. J., Peakman, M., Straten, P. T., Svane, Inge Marie, Sewell, A. K. & Dolton, G., Jan 2015, In: Journal of immunology (Baltimore, Md. : 1950). 194, 1, p. 463-474 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    The Targeting of Indoleamine 2,3 Dioxygenase -Mediated Immune Escape in Cancer

    Iversen, T. Z., Andersen, Mads Hald & Svane, Inge Marie, Jan 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 1, p. 19-24 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  94. Published

    Tryptophan 2,3-dioxygenase (TDO)-reactive T cells differ in their functional characteristics in health and cancer

    Hjortsø, M. D., Larsen, S. K., Kongsted, P., Met, Özcan, Frøsig, T. M., Andersen, G. H., Ahmad, S. M., Svane, Inge Marie, Becker, J. C., Straten, P. T. & Andersen, Mads Hald, Jan 2015, In: OncoImmunology. 4, 1, e968480.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α

    Riley, C. H., Hansen, M., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., Straten, P. T., Svane, Inge Marie & Jensen, M. K., Mar 2015, In: European Journal of Haematology. 94, 3, p. 227–234 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Confinement dependent chemotaxis in two-photon polymerized linear migration constructs with highly definable concentration gradients

    Hjortø, Gertrud Malene, Olsen, M. H., Svane, Inge Marie & Larsen, N. B., Apr 2015, In: Biomedical Microdevices. 17, 2, p. 1-10 10 p., 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial

    Weber, J. S., D'Angelo, S. P., Minor, D., Hodi, F. S., Gutzmer, R., Neyns, B., Hoeller, C., Khushalani, N. I., Miller, W. H., Lao, C. D., Linette, G. P., Thomas, L., Lorigan, P., Grossmann, K. F., Hassel, J. C., Maio, M., Sznol, M., Ascierto, P. A., Mohr, P., Chmielowski, B. & 8 others, Bryce, A., Svane, Inge Marie, Grob, J., Krackhardt, A. M., Horak, C., Lambert, A., Yang, A. S. & Larkin, J., Apr 2015, In: Lancet Oncology. 16, 4, p. 375-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Broadening the repertoire of melanoma-associated T-cell epitopes

    Frøsig, T. M., Lyngaa, R., Met, Özcan, Larsen, S. K., Donia, M., Svane, Inge Marie, Thor Straten, P. & Hadrup, S. R., May 2015, In: Cancer immunology, immunotherapy : CII. 64, 5, p. 609-20 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Neuroprotective and anti-inflammatory mechanisms are activated early in optic neuritis

    Tsakiri, A., Ravanidis, S., Lagoudaki, R., Poulatsidou, K., Svane, Inge Marie, Fredriksen, Jette Lautrup & Grigoriadis, N., May 2015, In: Acta Neurologica Scandinavica. 131, 5, p. 305-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers

    Dolton, G., Tungatt, K., Lloyd, A., Bianchi, V., Theaker, S. M., Trimby, A., Holland, C. J., Donia, M., Godkin, A. J., Cole, D. K., Straten, P. T., Peakman, M., Svane, Inge Marie & Sewell, A. K., Sep 2015, In: Immunology. 146, 1, p. 11-22 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  101. Published

    Reorienting the immune system in the treatment of cancer by using anti-PD-1 and anti-PD-L1 antibodies

    Borch, T. H., Donia, M., Andersen, Mads Hald & Svane, Inge Marie, Sep 2015, In: Drug Discovery Today. 20, 9, p. 1127-34 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  102. Published

    Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity

    Donia, M., Andersen, R., Kjeldsen, J. W., Fagone, P., Munir, S., Nicoletti, F., Andersen, Mads Hald, Thor Straten, P. & Svane, Inge Marie, 15 Sep 2015, In: Cancer Research. 75, 18, p. 3747-59 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05

    Frøsig, T. M., Yap, J., Seremet, T., Lyngaa, R., Svane, Inge Marie, Thor Straten, P., Heemskerk, M. H. M., Grotenbreg, G. M. & Hadrup, S. R., Oct 2015, In: Cytometry. Part A. 87, 10, p. 967-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Low-dose prednisolone in first-line docetaxel for patients with metastatic castration-resistant prostate cancer: is there a clinical benefit?

    Kongsted, P., Svane, Inge Marie, Lindberg, H., Daugaard, G. & Sengeløv, L., Nov 2015, In: Urologic Oncology: Seminars and Original Investigations. 33, 11, p. 494.e15-20

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Tumor-infiltrating lymphocytes for the treatment of metastatic cancer

    Geukes Foppen, M. H., Donia, M., Svane, Inge Marie & Haanen, J. B. A. G., Dec 2015, In: Molecular Oncology. 9, 10, p. 1918-35 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  106. 2016
  107. Published

    Behandlingen af BRAF-muteret metastatisk melanom med BRAF/MEK-inhibitorer bedrer prognosen

    Boyles, T. B., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V02160126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment

    Martinenaite, E., Munir Ahmad, S., Hansen, M., Met, Özcan, Westergaard, M. W., Larsen, S. K., Klausen, T. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2016, In: OncoImmunology. 5, 11, 10 p., e1238541.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Immuncheckpointantistoffer øger overlevelsen for patienter med metastatisk melanom

    Fløe, L. E., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V01160070.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Immune monitoring using mRNA-transfected dendritic cells

    Borch, T. H., Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Humana Press, Vol. 1428. p. 245-259 15 p. (Methods in Molecular Biology, Vol. 1428).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  111. Published

    Immunological correlates of treatment and response in stage IV malignant melanoma patients treated with Ipilimumab

    Bjoern, J., Juul Nitschke, N., Zeeberg Iversen, T., Schmidt, H., Fode, K. & Svane, Inge Marie, 2016, In: OncoImmunology. 5, 4, 10 p., e1100788.

    Research output: Contribution to journalJournal articleResearchpeer-review

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