Helle Krogh Johansen

Clinical Professor

Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
- helle.krogh.johansen@regionh.dk
- https://ikm.ku.dk/
Phone: +4531228406

Member of:

Clinical Microbiology

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2024
Published
Adaptive Evolution of Pseudomonas aeruginosa in Human Airways Shows Phenotypic Convergence Despite Diverse Patterns of Genomic Changes
Espaillat, A., Colque, C. A., Rago, D., La Rosa, R., Molin, S. & Johansen, Helle Krogh, 2024, In: MOLECULAR BIOLOGY AND EVOLUTION . 41, 2, 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance
Laborda, P., Lolle, S., Hernando-Amado, S., Alcalde-Rico, M., Aanæs, Kasper, Martínez, J. L., Molin, S. & Johansen, Helle Krogh, 2024, In: Nature Communications. 15, 1, 12 p., 2584.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Predicting the primary infection source of Escherichia coli bacteremia using virulence-associated genes
Ilsby, C. S., Hertz, Frederik Boëtius, Westh, Henrik T., Monk, J., Worning, P., Johansen, Helle Krogh, Hansen, Katrine Hartung & Pinholt, M., 2024, In: European Journal of Clinical Microbiology and Infectious Diseases. 43, 4, p. 641-648 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ventriculostomy-associated infection (VAI) in patients with acute brain injury—a retrospective study
Nielsen, P., Olsen, M. H., Willer-Hansen, R. S., Hauerberg, J., Johansen, Helle Krogh, Andersen, A. B., Knudsen, J. D. & Møller, Kirsten, 2024, In: Acta Neurochirurgica. 166, 1, 10 p., 128.
Research output: Contribution to journal › Journal article › Research › peer-review
2023
Published
A Dedicated Mycosis Flask Increases the Likelihood of Identifying Candidemia Sepsis
Ahlström, M. G., Antsupova, V. S., Pedersen, M., Johansen, Helle Krogh, Hansen, D. S. & Knudsen, I. J. D., 2023, In: Journal of Fungi. 9, 4, 15 p., 441.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination
Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup, Pressler, T., Johansen, Helle Krogh & Kolpen, Mette, 2023, In: APMIS. 131, 8, p. 419-425
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Inhalation devices and inhaled corticosteroids particle size influence on severe pneumonia in patients with chronic obstructive pulmonary disease: a nationwide cohort study
Heerfordt, C. K., Rønn, C., Harboe, Zitta F B Barrella, Ingebrigtsen, T. S., Svorre Jordan, A., Wilcke, Jon Torgny Rostrup, Bonnesen, B., Biering-Sørensen, Tor, Sørensen, Rikke, Holler, J. G., Itenov, Theis Skovsgaard, Johansen, Helle Krogh, Sivapalan, P., Eklöf, J. & Jensen , Jens-Ulrik Stæhr , 2023, In: BMJ Open Respiratory Research. 10, 1, 10 p., e001814. .
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Long-term evolution of antibiotic tolerance in Pseudomonas aeruginosa lung infections
Ghoul, M., Andersen, Sandra Breum, Marvig, R. L., Johansen, Helle Krogh, Jelsbak, L., Molin, S., Perron, G. & Griffin, A. S., 2023, In: Evolution Letters. 7, 6, p. 389–400 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2022
Published
Achromobacter spp. in a Cohort of Non-Selected Pre-and Post-Lung Transplant Recipients
Crone, C. G., Rezahosseini, O., Schultz, H. H. L., Qvist, T., Johansen, Helle Krogh, Nielsen, Susanne Dam & Perch, Michael, 2022, In: Pathogens. 11, 2, 181.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Diagnostic criteria of CNS infection in patients with external ventricular drainage after traumatic brain injury: a pilot study
Willer-Hansen, R. S., Olsen, M. H., Hauerberg, J., Johansen, Helle Krogh, Andersen, Å. B. & Møller, Kirsten, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 507-515 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Inter-species interactions alter antibiotic efficacy in bacterial communities
Bottery, M. J., Matthews, J. L., Wood, A. J., Johansen, Helle Krogh, Pitchford, J. W. & Friman, V. P., 2022, In: ISME Journal. 16, p. 812–821
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams
Colque, C. A., albarracín Orio, A. G., Tomatis, P. E., Dotta, G., Moreno, D. M., Hedemann, L. G., Hickman, R. A., Sommer, L. M., Feliziani, S., Moyano, A. J., Bonomo, R. A., Johansen, Helle Krogh, Molin, S., Vila, A. J. & Smania, A. M., 2022, In: mBio. 13, 5
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance
Goltermann, L., Andersen, Kasper Langebjerg, Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1594-1601
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance: author's response
Goltermann, L., Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1667-1668 2 p.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
New concepts in antimicrobial resistance in cystic fibrosis respiratory infections
Drevinek, P., Canton, R., Johansen, Helle Krogh, Hoffman, L., Coenye, T., Burgel, P. & Davies, J. C., 2022, In: Journal of Cystic Fibrosis. 21, 6, p. 937-945 9 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease
Eklöf, J., Misiakou, M. A., Sivapalan, P., Armbruster, K., Browatzki, A., Nielsen, T. L., Lapperre, T. S., Andreassen, H. F., Janner, J., Ulrik, C. S., Gabrielaite, M., Johansen, H. K., Jensen, A., Nielsen, T. V., Hertz, F. B., Ghathian, K., Calum, H., Wilcke, T., Seersholm, N., Jensen, J. U. S. & 1 others, Marvig, R. L., 2022, In: Clinical Microbiology and Infection. 28, 7, p. 990-995 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution
La Rosa, R., Johansen, Helle Krogh & Molin, S., 2022, In: Antibiotics. 11, 3, 419.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs
Luján, A. M., Paterson, S., Hesse, E., Sommer, L. M., Marvig, R. L., Sharma, M. D., Alseth, E. O., Ciofu, Oana, Smania, A. M., Molin, S., Johansen, Helle Krogh & Buckling, A., 2022, In: Nature Ecology and Evolution. 6, p. 979–988
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial
Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., Rades, T. & 17 others, Johansen, Helle Krogh, Westh, Henrik T., Kim, W., Mylonakis, E., Friis, C., Guardabassi, Luca, Pace, J., Lundberg, C. V., M'Zali, F., Butty, P., Sørensen, N., Nielsen, H. B., Toft-Kehler, R., Guttman-Yassky, E., Stingl, G., Zeitlinger, M. & Sommer, M., 2022, In: Clinical and Translational Medicine. 12, 5, e790.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Use of inhaled antibiotics among Danish patients with cystic fibrosis
Møller, R., Nielsen, B. U., Faurholt-Jepsen, D., Katzenstein, T. L., Skov, M., Philipsen, L. K. D., Pressler, T., Johansen, Helle Krogh & Qvist, T., 2022, In: Pediatric Pulmonology. 57, 7, p. 1726-1734 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2021
Published
Achromobacter spp. genetic adaptation in cystic fibrosis
Gabrielaite, M., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marvig, R. L., 2021, In: Microbial genomics. 7, 7, 13 p., 000582.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
Rossi, E., La Rosa, R., Bartell, J. A., Marvig, R. L., Haagensen, J. A. J., Sommer, L. M., Molin, S. & Johansen, Helle Krogh, 2021, In: Nature Reviews Microbiology. 19, p. 331–342
Research output: Contribution to journal › Review › Research › peer-review
Published
A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19
Backer, Vibeke, Sjöbring, U., Sonne, J., Weiss, A., Hostrup, Morten, Johansen, Helle Krogh, Becker, V., Sonne, D. P., Balchen, T., Jellingsø, M. & Sommer, M. O. A., 2021, In: The Lancet Regional Health - Europe. 4, 8 p., 100084.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A retrospective review of Achromobacter species and antibiotic treatments in patients with primary ciliary dyskinesia
Holgersen, M. G., Marthin, J. K., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: Chronic Respiratory Disease. 18
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Adaptive interactions of achromobacter spp. With pseudomonas aeruginosa in cystic fibrosis chronic lung co-infection
Sandri, A., Haagensen, J. A. J., Veschetti, L., Johansen, Helle Krogh, Molin, S., Malerba, G., Signoretto, C., Boaretti, M. & Lleo, M. M., 2021, In: Pathogens. 10, 8, 12 p., 978.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Bacterial re-colonization occurs early after lung transplantation in cystic fibrosis patients
Holm, A. E., Schultz, H. H. L., Johansen, Helle Krogh, Pressler, T., Lund, T. K., Iversen, M. & Perch, Michael, 2021, In: Journal of Clinical Medicine. 10, 6, 11 p., 1275.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Co-delivery of ciprofloxacin and colistin using microcontainers for bacterial biofilm treatment
Birk, S. E., Mazzoni, C., Mobasharah Javed, M., Borre Hansen, M., Johansen, Helle Krogh, Anders Juul Haagensen, J., Molin, S., Hagner Nielsen, L. & Boisen, A., 2021, In: International Journal of Pharmaceutics. 599, 120420.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Compensatory evolution of Pseudomonas aeruginosa’s slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis
La Rosa, R., Rossi, E., Feist, A. M., Johansen, Helle Krogh & Molin, S., 2021, In: Nature Communications. 12, 1, 3186.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High-throughput dilution-based growth method enables time-resolved exo-metabolomics of Pseudomonas putida and Pseudomonas aeruginosa
Pedersen, B. H., Gurdo, N., Johansen, Helle Krogh, Molin, S., Nikel, P. I. & La Rosa, R., 2021, In: Microbial Biotechnology. 14, 5, p. 2214-2226
Research output: Contribution to journal › Journal article › Research › peer-review
Published
International BEAT-PCD consensus statement for infection prevention and control for primary ciliary dyskinesia in collaboration with ERN-LUNG PCD Core Network and patient representatives
Marthin, J. K., Lucas, J. S., Boon, M., Casaulta, C., Crowley, S., Destouches, D. M. S., Eber, E., Escribano, A., Haarman, E., Hogg, C., Maitre, B., Marsh, G., Martinu, V., Moreno-Galdó, A., Mussaffi, H., Omran, H., Pohunek, P., Rindlisbacher, B., Robinson, P., Snijders, D. & 4 others, Walker, W. T., Yiallouros, P., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: ERJ Open Research. 7, 3, 14 p., 00301-2021.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Omics-based tracking of Pseudomonas aeruginosa persistence in "eradicated" cystic fibrosis patients
Bartell, J. A., Sommer, L. M., Marvig, R. L., Skov, M., Pressler, T., Molin, S. & Johansen, Helle Krogh, 2021, In: The European Respiratory Journal. 57, 4, 2000512.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Transmission and Antibiotic Resistance of Achromobacter in Cystic Fibrosis
Gabrielaite, M., Bartell, J. A., Nørskov-Lauritsen, N., Pressler, T., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marviga, R. L., 2021, In: Journal of Clinical Microbiology. 59, 4, e02911-20.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Update 2016–2018 of the Nationwide Danish Fungaemia Surveillance Study: Epidemiologic Changes in a 15-Year Perspective
Risum, M., Astvad, K., Johansen, Helle Krogh, Schønheyder, H. C., Rosenvinge, F., Knudsen, J. D., Hare, R. K., Datcu, R., Røder, B. L., Antsupova, V. S., Kristensen, L., Gertsen, J. B., Møller, J. K., Dzajic, E., Søndergaard, T. S. & Arendrup, Maiken Cavling, 2021, In: Journal of Fungi. 7, 6, 16 p., 491.
Research output: Contribution to journal › Journal article › Research › peer-review
2020
Published
Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms
Birk, S. E., Haagensen, J. A. J., Johansen, Helle Krogh, Molin, S., Nielsen, L. H. & Boisen, A., May 2020, In: Advanced Healthcare Materials. 9, 10, 10 p., 1901779.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypermutator Pseudomonas Aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients
Colque, C. A., Albarracín Orio, A. G., Feliziani, S., Marvig, R. L., Tobares, A. R., Johansen, Helle Krogh, Molin, S. & Smania, A. M., Apr 2020, In: Antimicrobial Agents and Chemotherapy. 64, 5, p. e02142-19
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Nanograss sensor for selective detection of Pseudomonas aeruginosa by pyocyanin identification in airway samples
Alatraktchi, F. A. Z. A., Dimaki, M., Støvring, N., Johansen, Helle Krogh, Molin, S. & Svendsen, W. E., Mar 2020, In: Analytical Biochemistry. 593, 6 p., 113586.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypermutation as an Evolutionary Mechanism for Achromobacter Xylosoxidans in Cystic Fibrosis Lung Infection
Veschetti, L., Sandri, A., Johansen, Helle Krogh, Lleò, M. M. & Malerba, G., Feb 2020, In: Pathogens. 9, 2, 10 p., 72.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A new device to prevent contamination of nasal swabs by Staphylococcus aureus in acute rhinosinutitis
Kirkegaard Kiaer, E., Hakansson, K., Orntoft, S., Bartels, Mette Damkjær, Johansen, Helle Krogh & von Buchwald, Christian, 2020, In: Rhinology Online. 3, p. 39-44
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments
Sommer, L. M., Johansen, Helle Krogh & Molin, S., 2020, In: Microbial Genomics. 6, 5, p. 1-6 6 p., 000370.
Research output: Contribution to journal › Review › Research › peer-review
Published
Azole-Resistant Aspergillus fumigatus Among Danish Cystic Fibrosis Patients: Increasing Prevalence and Dominance of TR34/L98H
Risum, M., Hare, R. K., Gertsen, J. B., Kristensen, L., Johansen, Helle Krogh, Helweg-Larsen, J., Abou-Chakra, N., Pressler, T., Skov, M., Jensen-Fangel, S. & Arendrup, Maiken Cavling, 2020, In: Frontiers in Microbiology. 11, 10 p., 1850.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment
Bartell, J. A., Cameron, D. R., Mojsoska, B., Haagensen, J. A. J., Pressler, T., Sommer, L. M., Lewis, K., Molin, S. & Johansen, Helle Krogh, 2020, In: PLOS Pathogens. 16, 12 December, e1009112.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Gene loss and acquisition in lineages of pseudomonas aeruginosa evolving in cystic fibrosis patient airways
Gabrielaite, M., Johansen, Helle Krogh, Molin, S., Nielsen, Finn Cilius & Marvig, R. L., 2020, In: mBio. 11, 5, p. 1-16 16 p., e02359-20.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs
Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.
Research output: Contribution to journal › Letter › Research › peer-review
2019
Published
Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate
Halfon, Y., Jimenez-Fernandez, A., La Rosa, R., Espinosa Portero, R., Johansen, Helle Krogh, Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S. & Yonath, A., 29 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22275-22281 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients
La Rosa, R., Johansen, Helle Krogh & Molin, S., 2019, In: Metabolites. 9, 10, 15 p., 234.
Research output: Contribution to journal › Review › Research › peer-review
Published
Evolutionary highways to persistent bacterial infection
Bartell, J. A., Sommer, L. M., Haagensen, J. A. J., Loch, A., Espinosa, R., Molin, S. & Johansen, Helle Krogh, 2019, In: Nature Communications. 10, 1, 13 p., 629.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis
Burgener, E. B., Sweere, J. M., Bach, M. S., Secor, P. R., Haddock, N., Jennings, L. K., Marvig, R. L., Johansen, Helle Krogh, Rossi, E., Cao, X., Tian, L., Nedelec, L., Molin, S., Bollyky, P. L. & Milla, C. E., 2019, In: Science Translational Medicine. 11, 488, 12 p., eaau9748.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Reconciling Antimicrobial Susceptibility Testing and Clinical Response in Antimicrobial Treatment of Chronic Cystic Fibrosis Lung Infections
Waters, V. J., Kidd, T. J., Canton, R., Ekkelenkamp, M. B., Johansen, Helle Krogh, LiPuma, J. J., Bell, S. C., Elborn, J. S., Flume, P. A., VanDevanter, D. R., Gilligan, P. & Antimicrobial Resistance International Working Group in Cystic Fibrosis , A. R. I. W. G. I. C. F., 2019, In: Clinical Infectious Diseases. 69, 10, p. 1812-1816
Research output: Contribution to journal › Journal article › Research › peer-review
2018
Published
Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia
Scott, W. K., Medie, F. M., Ruffin, F., Sharma-Kuinkel, B. K., Cyr, D. D., Guo, S., Dykxhoorn, D. M., Skov, R. L., Bruun, N. E., Dahl, A., Lerche, C. J., Petersen, A., Larsen, A. R., Lauridsen, T. K., Johansen, H. K., Ullum, H., Sørensen, E., Hassager, C., Bundgaard, H., Schønheyder, H. C. & 9 others, Torp-Pedersen, C., Østergaard, L. B., Arpi, M., Rosenvinge, F., Erikstrup, L. T., Chehri, M., Søgaard, P., Andersen, P. S. & Fowler, V. G., Oct 2018, In: P L o S Genetics. 14, 10, p. 1-22 e1007667.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Human Genetic Susceptibility to Native Valve Staphylococcus aureus Endocarditis in Patients With S. aureus Bacteremia: Genome-Wide Association Study
Moreau, K., Clemenceau, A., Le Moing, V., Messika-Zeitoun, D., Andersen, P. S., Bruun, Niels Eske, Skov, R. L., Couzon, F., Bouchiat, C., Erpelding, M. L., van Belkum, A., Bossé, Y., Duval, X., Vandenesch, F., The French VIRSTA-AEPEI, COFRASA Study Groups and the Danish DANSAB Study Group, T. F. V. C. S. G. A. T. D. D. S. G., Johansen, Helle Krogh, Hassager, Christian & Ullum, H., 4 Apr 2018, In: Frontiers in Microbiology. 9, p. 1-11 640.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Update from a 12-year nationwide fungemia surveillance: Increasing intrinsic and acquired resistance causes concern
Astvad, K. M. T., Johansen, Helle Krogh, Røder, B. L., Rosenvinge, F. S., Knudsen, J. D., Lemming, L., Schønheyder, H. C., Hare, R. K., Kristensen, L., Nielsen, L., Gertsen, J. B., Dzajic, E., Pedersen, M., Østergård, C., Olesen, B., Søndergaard, T. S. & Arendrup, Maiken Cavling, 1 Apr 2018, In: Journal of Clinical Microbiology. 56, 4, 15 p., e01564.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Drug-Driven Phenotypic Convergence Supports Rational Treatment Strategies of Chronic Infections
Imamovic, L., Ellabaan, M. M. H., Dantas Machado, A. M., Citterio, L., Wulff, T., Molin, S., Johansen, Helle Krogh & Sommer, M. O. A., 11 Jan 2018, In: Cell. 172, 1-2, p. 121-134.e14
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study
Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Convergent metabolic specialization through distinct evolutionary paths in Pseudomonas aeruginosa
La Rosa, R., Johansen, Helle Krogh & Molina, S., 2018, In: mBio. 9, 2, 15 p., e00269-18.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Defining antimicrobial resistance in cystic fibrosis
Kidd, T. J., Canton, R., Ekkelenkamp, M., Johansen, Helle Krogh, Gilligan, P., LiPuma, J. J., Bell, S. C., Elborn, J. S., Flume, P. A., VanDevanter, D. R., Waters, V. J. & Antimicrobial Resistance in Cystic Fibrosis International Working Group, A. R. I. C. F. I. W. G., 2018, In: Journal of Cystic Fibrosis. 17, 6, p. 696-704 9 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
High incidence of candidaemia in a nationwide cohort: Underlying diseases, risk factors and mortality
Lausch, K. R., Søgaard, M., Rosenvinge, F. S., Johansen, Helle Krogh, jfn630, jfn630, Røder, B., Mortensen, K. L., Nielsen, L., Lemming, L., Olesen, B., Leitz, C., Kristensen, L., Dzajic, E., Østergaard, L., Schønheyder, H. C. & Arendrup, Maiken Cavling, 2018, In: International Journal of Infectious Diseases. 76, p. 58-63 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
Rossi, E., Falcone, M., Molin, S. & Johansen, Helle Krogh, 2018, In: Nature Communications. 9, 1, p. 1-13 3459.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts
Frimodt-Møller, Jakob, Rossi, E., Haagensen, J. A. J., Falcone, M., Molin, S. & Johansen, Helle Krogh, 2018, In: Scientific Reports. 8, 1, p. 1-13 12512.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa
Alatraktchi, F. A. Z. A., Noori, J. S., Tanev, G. P., Mortensen, J., Dimaki, M., Johansen, Helle Krogh, Madsen, J., Molin, S. & Svendsen, W. E., 2018, In: PLoS ONE. 13, 3, 9 p., e0194157.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Privatisation rescues function following loss of cooperation
Andersen, Sandra Breum, Ghoul, M., Marvig, R. L., Lee, Z., Molin, S., Johansen, Helle Krogh & Griffin, A. S., 2018, In: eLife. 7, p. 1-27 27 p., e38594.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The accessibility of topical treatment in the paranasal sinuses on operated cystic fibrosis patients assessed by scintigraphy
Aanæs, Kasper, Alanin, M. C., Nielsen, Kim G., Jørgensen, M. M., von Buchwald, Christian, Høiby, N., Johansen, Helle Krogh, Johannesen, H. H. & Mortensen, Jann, 2018, In: Rhinology. 56, 3, p. 268-273
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The small RNA ErsA of Pseudomonas aeruginosa contributes to biofilm development and motility through post-transcriptional modulation of AmrZ
Falcone, M., Ferrara, S., Rossi, E., Johansen, Helle Krogh, Molin, S. & Bertoni, G., 2018, In: Frontiers in Microbiology. 9, FEB, 238.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment
Lausch, K. R., Søgaard, M., Rosenvinge, F. S., Johansen, Helle Krogh, jfn630, jfn630, Røder, B. L., Mortensen, K. L., Nielsen, L., Lemming, L., Olesen, B., Leitz, C., Kristensen, L., Dzajic, E., Østergaard, L. J., Schønheyder, H. C. & Arendrup, Maiken Cavling, 2018, In: Infection and Drug Resistance. 11, p. 2449-2459 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2017
Published
Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?
Jensen, Ramon Gordon, Johansen, Helle Krogh, Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R. & Homøe, Preben, Jul 2017, In: European Archives of Oto-Rhino-Laryngology. 274, 7, p. 2741-2747 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia
Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, Kim G., Johansen, Helle Krogh & von Buchwald, Christian, Mar 2017, In: International Forum of Allergy Rhinology. 7, 3, p. 240-247
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats
Søe, Niels Henrik, Jensen, N. V., Jensen, Asger Lundorff, Koch, J., Poulsen, Steen Seier, Pier, G. B. & Johansen, Helle Krogh, 2017, In: In Vivo. 31, 1, p. 45-50 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Clinical care of children with primary ciliary dyskinesia
Lucas, J. S., Alanin, M. C., Collins, S., Harris, A., Johansen, Helle Krogh, Nielsen, Kim G., Papon, J. F., Robinson, P. & Walker, W. T., 2017, In: Expert Review of Respiratory Medicine. 11, 10, p. 779-790 12 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Diversity, prevalence, and longitudinal occurrence of type II toxin-antitoxin systems of Pseudomonas aeruginosa infecting cystic fibrosis lungs
Andersen, Sandra Breum, Ghoul, M., Griffin, A. S., Petersen, Bent, Johansen, Helle Krogh & Molin, S., 2017, In: Frontiers in Microbiology. 8, 12 p., 1180.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Is parotid saliva is sterile on entry to the oral cavity ?
Schrøder, S., Jensen, A. B., Eickhardt-Dalbøge, S. R., Johansen, Helle Krogh & Homøe, Preben, 2017, In: Acta Oto-Laryngologica. 137, 7, p. 762-764 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients
Lauridsen, R. K., Sommer, L. M., Johansen, Helle Krogh, Rindzevicius, T., Molin, S., Jelsbak, L., Engelsen, Søren Balling & Boisen, A., 2017, In: Scientific Reports. 7, 7 p., 45264.
Research output: Contribution to journal › Journal article › Research › peer-review
2016
Published
Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways?
Sommer, L. M., Marvig, R. L., Luján, A., Koza, A., Pressler, T., Molin, S. & Johansen, Helle Krogh, 9 Aug 2016, In: BMC Genomics. 17, 10 p., 589.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction
Michelsen, C. F., Hossein Khademi, S. M., Johansen, Helle Krogh, Ingmer, Hanne, Dorrestein, P. C. & Jelsbak, L., Jun 2016, In: I S M E Journal. 10, 6, p. 1323-1336
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry
Alatraktchi, F. A., Andersen, S. B., Johansen, Helle Krogh, Molin, S. & Svendsen, W. E., 19 Mar 2016, In: Sensors. 16, 3, 10 p., 408.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Posttreatment Antifungal Resistance among Colonizing Candida Isolates in Candidemia Patients: Results from a Systematic Multicenter Study
Jensen, R. H., Johansen, Helle Krogh, Søes, L. M., Lemming, L. E., Rosenvinge, F. S., Nielsen, L., Olesen, B., Kristensen, L., Dzajic, E., Astvad, K. M. T. & Arendrup, M. C., Mar 2016, In: Antimicrobial Agents and Chemotherapy. 60, 3, p. 1500-8 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Bacterial evolution in PCD and CF patients follows the same mutational steps
Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, Kim G., Høiby, Niels, von Buchwald, Christian, Molin, S. & Johansen, Helle Krogh, 2016, In: Scientific Reports. 6, 8 p., 28732.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease: Review
Gøtzsche, P. C. & Johansen, Helle Krogh, 2016, In: Cochrane Database of Systematic Reviews. 9, p. 1-27 27 p., CD007851.
Research output: Contribution to journal › Review › Research › peer-review
Published
Sinus surgery postpones chronic gram-negative lung infection: Cohort study of 106 patients with cystic fibrosis
Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, Helle Krogh & von Buchwald, Christian, 2016, In: Rhinology. 54, 3, p. 206-213 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2015
Published
A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia
Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients
Marvig, R. L., Dolce, D., Sommer, L. M., Petersen, Bent, Ciofu, Oana, Campana, S., Molin, S., Taccetti, G. & Johansen, Helle Krogh, 19 Oct 2015, In: B M C Microbiology. 15, 13 p., 218.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection
Jorgensen, K. M., Wassermann, T., Johansen, Helle Krogh, Christiansen, L. E., Molin, S., Høiby, Niels & Ciofu, Oana, Jul 2015, In: Microbiology. 161, 7, p. 1447-1462 16 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Antibiofilm Properties of Acetic Acid
Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients
Wessman, M., Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R., Johansen, Helle Krogh & Homøe, Preben, May 2015, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 272, 5, p. 1079-1085 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Monitoring meticillin resistant Staphylococcus aureus and its spread in Copenhagen, Denmark, 2013, through routine whole genome sequencing
Bartels, Mette Damkjær, Larner-Svensson, H., Meiniche, H., Kristoffersen, K., Schønning, Kristian, Nielsen, J. B., Rohde, S. M., Christensen, L. B., Skibsted, A. W., Jarlov, J. O., Johansen, Helle Krogh, Andersen, L. P., Petersen, I. S., Crook, D. W., Bowden, R., Boye, K., Worning, P. & Westh, Henrik T., 30 Apr 2015, In: Eurosurveillance. 20, 17, 9 p., 21112.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study
Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia
Alanin, M. C., Johansen, Helle Krogh, Aanaes, K., Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G. & von Buchwald, Christian, Jan 2015, In: Acta Oto-Laryngologica. 135, 1, p. 58-63 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Kompendium i mikrobiologi og infektionsmedicin
Høiby, N., Skinhøj, P., Andersen, Å. B., Andersen, Leif Percival, Arendrup, M. C., Christiansen, C. B., Ciofu, Oana, Gerstoft, Jan, Johansen, Helle Krogh, Kemp, M., Kurtzhals, Jørgen, Nielsen, L. P., Lyngsøe Svejgaard, E., Theander, Thor Grundtvig & Thomsen, Allan Randrup, 2015, 1. ed. FADL's Forlag.
Research output: Book/Report › Book › Education
Published
Long-term social dynamics drive loss of function in pathogenic bacteria
Andersen, Sandra Breum, Marvig, R. L., Molin, S., Johansen, Helle Krogh & Griffin, A. S., 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 34, p. 10756-10761 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis
Johansen, Helle Krogh & Gøtzsche, P. C., 2015, In: Cochrane Database of Systematic Reviews. 2015, 8, p. 1-19 19 p., CD001399.
Research output: Contribution to journal › Review › Research › peer-review
2014
Published
Comparing whole-genome sequencing with sanger sequencing for spa typing of methicillin-resistant staphylococcus aureus
Bartels, Mette Damkjær, Petersen, A., Worning, P., Nielsen, J. B., Larner-Svensson, H., Johansen, Helle Krogh, Andersen, Leif Percival, Jarløv, J. O., Boye, K., Larsen, A. R. & Westh, Henrik T., 1 Dec 2014, In: Journal of clinical microbiology. 52, 12, p. 4305-4308 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Increasing prevalence of group B streptococcal infection among pregnant women
Petersen, K. B., Johansen, Helle Krogh, Rosthøj, Susanne, Krebs, Lone, Pinborg, Anja & Hedegaard, M., Sep 2014, In: Danish Medical Journal. 61, 9, p. 1-5 5 p., A4908.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Epiglottitis with an abscess caused by Haemophilus parainfluenzae
Juul, M. L., Johansen, Helle Krogh & Homøe, Preben, 17 Mar 2014, In: Ugeskrift for Laeger. 176, 12A, p. 2-3 2 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Amphotericin B lipid soluble formulations versus amphotericin B in cancer patients with neutropenia
Johansen, Helle Krogh & Gøtzsche, P. C., 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-30 30 p., CD000969.
Research output: Contribution to journal › Review › Research › peer-review
Published
Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients
Johansen, Helle Krogh & Gøtzsche, P. C., 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-38 38 p., CD000239.
Research output: Contribution to journal › Review › Research › peer-review
Published
Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa
Markussen, T., Marvig, R. L., Gómez-Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., 2014, In: mBio. 5, 5, p. 1-10 10 p., e01592-14.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Nystatin prophylaxis and treatment in severely immunodepressed patients
Gøtzsche, P. C. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-23 23 p., CD002033.
Research output: Contribution to journal › Review › Research › peer-review
Published
Routine versus selective antifungal administration for control of fungal infections in patients with cancer
Gøtzsche, P. C. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-48 48 p., CD000026.
Research output: Contribution to journal › Review › Research › peer-review
Published
Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?
Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia
Jørgensen, K. J., Gøtzsche, P. C., Dalbøge, C. S. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 2, p. 1-17 17 p.
Research output: Contribution to journal › Review › Research › peer-review
2013
Published
P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs
Ciofu, Oana, Johansen, Helle Krogh, Aanæs, Kasper, Wassermann, T., Alhede, M., von Buchwald, Christian & Høiby, Niels, 8 Mar 2013, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 12, 6, p. 729-736 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF
Dalbøge, C. S., Pressler, T., Høiby, Niels, Nielsen, Kim G. & Johansen, Helle Krogh, Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 42-8 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Clinical effects of sinus surgery and adjuvant therapy in cystic fibrosis patients - can chronic lung infections be postponed?
Aanæs, Kasper, Johansen, Helle Krogh, Skov, M., Buchvald, F. F., Hjuler, Thomas, Pressler, T., Høiby, Niels, Nielsen, Kim G. & von Buchwald, Christian, 2013, In: Rhinology. 51, 3, p. 222-230 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model
van de Weert-van Leeuwen, P. B., de Vrankrijker, A. M. M., Fentz, J., Ciofu, Oana, Wojtaszewski, Jørgen F P, Arets, H. G. M., Hulzebos, H. J., van der Ent, C. K., Beekman, J. M. & Johansen, Helle Krogh, 2013, In: P L o S One. 8, 12, 7 p., e82869.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis
Aanaes, K., von Buchwald, Christian, Hjuler, Thomas, Skov, M., Alanin, M. & Johansen, Helle Krogh, 2013, In: American Journal of Rhinology & Allergy. 27, 1, p. e1-4 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2012
Published
Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective
Folkesson, A., Jelsbak, L., Yang, L., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels & Molin, S., Dec 2012, In: Nature Reviews. Microbiology. 10, 12, p. 841-851 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response
Johansen, Helle Krogh, Aanæs, Kasper, Pressler, T., Nielsen, Kim G., Fisker, J., Skov, M., Høiby, Niels & von Buchwald, Christian, Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 525-531 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa
Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates
Tramper-Stranders, G. A., van der Ent, C. K., Molin, S., Yang, L., Hansen, S. K., Rau, M. H., Ciofu, Oana, Johansen, Helle Krogh & Wolfs, T. F. W., Jun 2012, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 18, 6, p. 567-74 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients
Moskowitz, S. M., Brannon, M. K., Dasgupta, N., Pier, M., Sgambati, N., Miller, A. K., Selgrade, S. E., Miller, S. I., Denton, M., Conway, S. P., Johansen, Helle Krogh & Høiby, Niels, Feb 2012, In: Antimicrobial Agents and Chemotherapy. 56, 2, p. 1019-1030 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A novel knee prosthesis model of implant-related osteo- myelitis in rats
Søe, N. H., Jensen, N. V., Nürnberg, B. M., Jensen, Asger Lundorff, Koch, J., Poulsen, Steen Seier, Pier, G. & Johansen, Helle Krogh, 2012, In: Acta Orthopaedica (Print Edition). 84, 1, p. 92-97 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients
Rasmussen, J., Aanæs, Kasper, Norling, R., Nielsen, K. G., Johansen, Helle Krogh & von Buchwald, C., 2012, In: Journal of Cystic Fibrosis. 11, 2, p. 93-99
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection
Hansen, S. K., Rau, M. H., Johansen, Helle Krogh, Ciofu, Oana, Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, Kasper, von Buchwald, Christian, Høiby, Niels & Molin, S., 2012, In: I S M E Journal. 6, 1, p. 31-45
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Extensive endoscopic image-guided sinus surgery decreases BPI-ANCA in patients with cystic fibrosis
Aanæs, Kasper, Rasmussen, N., Pressler, T., Segelmark, M., Johansen, Helle Krogh, Lindberg, U., Høiby, Niels, Carlsson, M., Wieslander, J. & Buchwald, C., 2012, In: Scandinavian Journal of Immunology. 76, 6, p. 573-9 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization
Aanæs, Kasper, Johansen, Helle Krogh, Poulsen, Steen Seier, Pressler, T., Buchwald, C. & Høiby, Niels, 2012, In: Journal of Cystic Fibrosis. 12, 1, p. 81-87 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2011
Published
PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients
Miller, A. K., Brannon, M. K., Stevens, L., Johansen, Helle Krogh, Selgrade, S. E., Miller, S. I., Høiby, Niels & Moskowitz, S. M., 3 Oct 2011, In: Antimicrobial Agents and Chemotherapy. 55, 12, p. 5761-5769
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis
Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Cystic Fibrosis. 10, 5, p. 318-25 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Diagnostic Issues, Clinical Characteristics, and Outcomes for Patients with Fungemia
Arendrup, M. C., Sulim, S., Holm, A., Nielsen, L., Nielsen, S. D., Knudsen, J. D., Drenck, N. E., Christensen, J. J. & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Clinical Microbiology. 49, 9, p. 3300-8 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance
Mortensen, K. L., Jensen, R. H., Johansen, Helle Krogh, Skov, M., Pressler, T., Howard, S. J., Leatherbarrow, H., Mellado, E. & Arendrup, M. C., 1 Jun 2011, In: Journal of Clinical Microbiology. 49, 6, p. 2243-51 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography
Rasmussen, R. V., Høst, U., Arpi, M., Hassager, Christian, Johansen, Helle Krogh, Korup, E., Schønheyder, H. C., Berning, J., Gill, S., Rosenvinge, F. S., Fowler, V. G., Møller, J. E., Skov, R. L., Larsen, C. T., Hansen, T. F., Mard, S., Smit, J., Andersen, P. S. & Bruun, Niels Eske, 1 Jun 2011, In: European Journal of Echocardiography. 12, 6, p. 414-20 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Differentiation of Candida glabrata, C. nivariensis and C. bracarensis based on fragment length polymorphism of ITS1 and ITS2 and restriction fragment length polymorphism of ITS and D1/D2 regions in rDNA
Mirhendi, H., Bruun, B., Schønheyder, H. C., Christensen, J. J., Fuursted, K., Gahrn-Hansen, B., Johansen, Helle Krogh, Nielsen, L., Knudsen, J. D. & Arendrup, M. C., 24 May 2011, In: European Journal of Clinical Microbiology & Infectious Diseases. 30, p. 1409-1416 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility
Mortensen, K. L., Johansen, Helle Krogh, Fuursted, K., Knudsen, J. D., Gahrn-Hansen, B., Jensen, R. H., Howard, S. & Arendrup, M. C., 4 May 2011, In: European Journal of Clinical Microbiology & Infectious Diseases. 30, 11, p. 1355-1363 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Evolutionary dynamics of bacteria in a human host environment
Yang, L., Jelsbak, L., Marvig, R. L., Damkiær, S., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels, Sommer, M. & Molin, S., 3 May 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-6 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Biofilm ved kronisk rhinosinuitis og cystisk fibrose
Fisker, J., Buchwald, C. V. & Johansen, Helle Krogh, 7 Feb 2011, In: Ugeskrift for Laeger. 173, 6, p. 417-9 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
National surveillance of fungemia in Denmark (2004 to 2009)
Arendrup, M. C., Bruun, B., Christensen, J. J., Fuursted, K., Johansen, Helle Krogh, Kjaeldgaard, P., Knudsen, J. D., Kristensen, L., Møller, J., Nielsen, L., Rosenvinge, F. S., Røder, B., Schønheyder, H. C., Thomsen, M. & Truberg, K., 1 Jan 2011, In: Journal of Clinical Microbiology. 49, 1, p. 325-34 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients
Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis
Aanæs, Kasper, Rickelt, L. F., Johansen, Helle Krogh, von Buchwald, Christian, Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The clinical impact of bacterial biofilms
Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65
Research output: Contribution to journal › Journal article › Research › peer-review
2010
Published
Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain
Mortensen, K. L., Mellado, E., Lass-Flörl, C., Rodriguez-Tudela, J. L., Johansen, Helle Krogh & Arendrup, M. C., 1 Nov 2010, In: Antimicrobial Agents and Chemotherapy. 54, 11, p. 4545-9 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Intravenous alpha-1 antitrypsin augmentation therapy: systematic review
Gøtzsche, P. C. & Johansen, Helle Krogh, 1 Sep 2010, In: Danish Medical Bulletin (Online). 57, 9, p. A4175
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients
Nørskov-Lauritsen, N., Johansen, Helle Krogh, Fenger, M. G., Nielsen, X. C., Pressler, T., Olesen, H. V. & Høiby, Niels, 1 Aug 2010, In: Journal of Clinical Microbiology. 48, 8, p. 2981-3 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection
Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, Oana, Johansen, Helle Krogh, Høiby, Niels & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chronic infection with Stenotrophomonas maltophilia in patients with cystic fibrosis at the Copenhagen CF centre
Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 17 Jun 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts
Rau, M. H., Hansen, S. K., Johansen, Helle Krogh, Thomsen, L. E., Workman, C. T., Nielsen, K. F., Jelsbak, L., Høiby, Niels, Yang, L. & Molin, S., 1 Jun 2010, In: Environmental Microbiology. 12, 6, p. 1643-58 16 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Gene transcription profiles of paired mucoid and non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis
Ciofu, O., Johansen, Helle Krogh, Wassermann, T., Aanæs, Kasper, Alhede, M. & Høiby, Niels, 23 May 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Diagnosis of bacterial biofilms in chronic sinusitis and pneumonia
Høiby, Niels, Buchwald, C. V., Aaanæs, K., Pressler, T. & Johansen, Helle Krogh, 10 Apr 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Molecular screening for Candida orthopsilosis and Candida metapsilosis among Danish Candida parapsilosis group blood culture isolates: proposal of a new RFLP profile for differentiation
Mirhendi, H., Bruun, B., Schønheyder, H. C., Christensen, J. J., Fuursted, K., Gahrn-Hansen, B., Johansen, Helle Krogh, Nielsen, L., Knudsen, J. D. & Arendrup, M. C., 1 Apr 2010, In: Journal of Medical Microbiology. 59, Pt 4, p. 414-20 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Increased incidence of Mycoplasma pneumoniae infections detected by laboratory-based surveillance in Denmark in 2010
Rasmussen, J., Voldstedlund, M., R L, A., Ellermann-Eriksen, S., Jensen, T. G., Johansen, Helle Krogh, Kolmos, B., Mølvadgaard, M., Nielsen, S. S., Olsen, E., Schønning, Kristian & Uldum, S. A., 1 Jan 2010, In: Eurosurveillance (Online Edition). 15, 45
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease
Gøtzsche, P. C. & Johansen, Helle Krogh, 1 Jan 2010, In: Cochrane Database of Systematic Reviews. 7, p. CD007851
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Active immunization against Staphylococcus aureus (oca+) periprosthetic osteomyelitis in rats
Koch, J., Johansen, Helle Krogh, Vedel-Jensen, N., Jensen, A., poulsen, S. & Søe, H., 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections
Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Effects of antibiotic treatment of Staphylococcus aureus infection in patients with cystic fibrosis at the Copenhagen CF centre
Dalbøge, C. S., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Emergence of ESBL-producing Klebsiella pneumoniae in Danish hospitals; this is in part explained by spread of one CTX-M-15 clone in Zealand
Lester, C., Olsen, S., Arpi, R. M., Fuursted, K., Hansen, D. S., Heltberg, O., Holm, A., Højbjerg, T., Jensen, K., Johansen, Helle Krogh, Justesen, U., Kemp, M., Knudsen, I. J. D., Røder, B., Frimodt-Møller, N. & Hammerum, A., 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Gene transcription profiles of paired mucoid & non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis
Johansen, Helle Krogh, Wassermann, T., Alhede, M., Aanæs, Kasper, Buchwald, C. V. & Høiby, Niels, 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Linezolid in infective endocarditis - it seems to work
Lauridsen, T., Bruun, L., Rasmussen, R., Moser, Claus Ernst, Johansen, Helle Krogh, Arpi, R. M., Hassager, Christian & Bruun, Niels Eske, 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
National Surveillance of Fungaemia in Denmark 2004-2009
Arendrup, M., Christensen, J., Fuursted, K., Johansen, Helle Krogh, Kjeldgaard, P., Knudsen, I. J. D., L, K., Møller, J., Nielsen, L., Olesen, L., Rosenvinge, F., Røder, B., Schønheyder, H., Thomsen, M. & Truberg, K., 2010. 0 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
The relation of biofilms to chronic otitis media and other ear related chronic infections
Homøe, Preben & Johansen, Helle Krogh, 2010, Biofilm Infections. Springer Publishing Company
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
2009
Published
Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media
Homøe, Preben, Bjarnsholt, Thomas, Wessman, M., Sørensen, H. C. F. & Johansen, Helle Krogh, 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Håndens akutte infektioner
Søe, Niels Henrik, Jensen, N. V., Dahlin, L. & Johansen, Helle Krogh, 2009, In: Ugeskrift for læger. 171, 14, p. 1189-93 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice
de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2008
Published
Har ny teknologi overflødiggjort Grams farvemetode? Dansk Selskab for Klinisk Mikrobiologi
Johansen, Helle Krogh, Bjarnsholt, Thomas, Høiby, Niels & Dansk Selskab for Klinisk Mikrobiologi, D. S. F. K. M., 17 Mar 2008, In: Ugeskrift for læger. 170, 12, p. 1041
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Den 2. kittelrevolution?
Høiby, Niels, Johansen, Helle Krogh, Tvede, M. & Andersen, Leif Percival, 2008, In: Ugeskrift for læger. 170, 14, p. 1169
Research output: Contribution to journal › Comment/debate › Research
Published
House dust mite control measures for asthma
Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Cochrane Database of Systematic Reviews. 2, p. CD001187-
Research output: Contribution to journal › Journal article › Research › peer-review
Published
House dust mite control measures for asthma: systematic review
Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Allergy. European Journal of Allergy and Clinical Immunology. 63, 6, p. 646-659 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections
Yang, L., Haagensen, J. A., Jelsbak, L., Sternberg, C., Høiby, Niels, Molin, S. & Johansen, Helle Krogh, 2008, In: Journal of Bacteriology. 190, 8, p. 2767-2776 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling
Johansen, H. K., Andersen, L. P., Skinhoj, P., Høiby, Niels & Johansen, Helle Krogh, 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 6. p. 223-298 75 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
Published
Pseudomonas aeruginosa diversity in distinct paediatric patient groups
Tramper-Stranders, G. A., Ent, C. K. V. D., Wolfs, T. F., Kimpen, J. L., Fleer, A., Johansen, U., Høiby, Niels & Johansen, Helle Krogh, 2008, In: Clinical Microbiology and Infection. 14, 10, p. 935-941 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Semi-national surveillance of fungaemia in Denmark 2004-2006: increasing incidence of fungaemia and numbers of isolates with reduced azole susceptibility
Arendrup, M. C., Fuursted, K., Gahrn-Hansen, B., Schonheyder, H. C., Knudsen, J. D., Jensen, I. M., Bruun, B., Christensen, J. J., Johansen, H. K., Johansen, Helle Krogh & Knudsen, J. D., 2008, In: Clinical Microbiology and Infection. 14, 5, p. 487-494 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients.
Johansen, Helle Krogh, Moskowitz, S. M., Ciofu, Oana, Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 5, p. 391-7 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes
Pamp, S. J., Gjermansen, M., Johansen, Helle Krogh & Tolker-Nielsen, Tim, 2008, In: Molecular Microbiology. 68, 1, p. 223-40 17 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis
Johansen, H. K., Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Cochrane Database of Systematic Reviews. 4, p. CD001399
Research output: Contribution to journal › Journal article › Research › peer-review
2007
Published
Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice
Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z. J., Johansen, Helle Krogh, Givskov, M. C. & Høiby, Niels, 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-3687 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.
Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ghost authorship in industry-initiated randomised trials
Gotzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, Mette Ewers, Altman, D. G. & Chan, A. W., 2007, In: PLoS Medicine. 4, 1, p. 47-52 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review?
Høiby, Niels & Johansen, Helle Krogh, 2007, In: Journal of Hospital Infection. 65, 4, p. 374-375 1 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mannan-binding lectin is a determinant of survival in infective endocarditis
Tran, C. T., Kjeldsen, K. E., Haunsø, Stig, Høiby, Niels, Johansen, Helle Krogh & Christiansen, M., 2007, In: Clinical and Experimental Immunology. 148, 1, p. 101-105 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.
Jelsbak, L., Johansen, Helle Krogh, Frost, A., Thøgersen, R., Thomsen, Line Elnif, Ciofu, Oana, Yang, L., Haagensen, J. A. J., Høiby, Niels & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-24 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2006
Published
Begrænsninger i publikationsrettighederne i industriinitierede kliniske forsøg: sekundærpublikation
Gotzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, M. T., Altman, D. G. & Chan, A. W., 2006, In: Ugeskrift for læger. 168, 25, p. 2467-2469 2 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Constraints on publication rights in industry-initiated clinical trials
Gøtzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, M. T., Altman, D. G. & Chan, A. W., 2006, In: JAMA - Journal of the American Medical Association. 295, 14, p. 1645-1646 1 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Flaws in design, analysis and interpretation of Pfizer's antifungal trials of voriconazole and uncritical subsequent quotations
Jorgensen, K. J., Johansen, Helle Krogh & Gøtzsche, P. C., 2006, In: Trials. 7, p. Art no. 3-
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Fungal infection-related mortality versus total mortality as an outcome in trials of antifungal agents
Due, A. K., Johansen, Helle Krogh & Gøtzsche, P. C., 2006, In: BMC Medical Research Methodology. 6, p. Art no. 40-
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa
Zuercher, A. W., Horn, M. P., Wu, H., Song, Z. J., Bundgaard, C. J., Johansen, Helle Krogh, Høiby, Niels, Marcus, P. & Lang, A. B., 2006, In: Vaccine. 24, 20, p. 4333-4342 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Voriconazole versus amphotericin B in cancer patients with neutropenia
Jorgensen, K. J., Gøtzsche, P. C. & Johansen, Helle Krogh, 2006, In: Cochrane Database of Systematic Reviews. 1, p. Art no. CD004707-
Research output: Contribution to journal › Journal article › Research › peer-review
2005
Published
Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))
Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
Ginseng modulerer immunresponset via påvirkning af cytokinproduktionen
Song, Z., Moser, C., Wu, H., Larsen, M. W., Johansen, Helle Krogh, Faber, V., Kharazmi, A. & Høiby, Niels, 2005, In: Ugeskrift for læger. 167, p. 3054-3056
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mycoplasma hominis-meningitis hos et præmaturt barn med hydrocefalus
Nielsen, P. E., Poulsen, S., Johansen, Helle Krogh & Greisen, Gorm, 2005, In: Ugeskrift for læger. 167, p. 2416-2417
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis
Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2004
Published
Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success? - A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection
Johansen, Helle Krogh, Nørregaard, L., Gøtzsche, P. C., Pressler, T., Koch, C. & Høiby, Niels, 2004, In: Pediatric Pulmonology. 37, 5, p. 427-432
Research output: Contribution to journal › Journal article › Research › peer-review
2003
Published
Epidemic spread of Pandoraea apista, a new pathogen causing severe lung disease in cystic fibrosis patients
Jorgensen, I. M., Johansen, Helle Krogh, Frederiksen, B., Pressler, T., Hansen, A., Vandamme, P., Høiby, Niels & Koch, C., 2003, In: Pediatric Pulmonology. 36(5), p. 439-446
Research output: Contribution to journal › Journal article › Research › peer-review
2002
Published
Amphotericin B lipid soluble formulations vs amphotericin B in cancer patients with neutropenia (Cochrane Review)
Johansen, Helle Krogh & Gøtzsche, P. C., 2002, The Cochrane Library, Issue 2. Oxford: Update Software (updated), p. -
Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
Published
Er indløsning af en ny antibiotikarecept efter behandling med sulfonamid eller pivmecillinam en validere metode til vurdering af behandlingssvigt?
Høiby, Niels, Tvede, M. & Johansen, Helle Krogh, 2002, In: Ugeskrift for læger. 164, p. 920-921
Research output: Contribution to journal › Journal article › Research › peer-review
2001
Published
Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis
Jensen, P., Johansen, Helle Krogh, Carmi, P., Høiby, Niels & Cohen, I. R., 2001, In: J. Autoimmunity. 17, p. 165-172
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Diagnostik ved infektionssygdomme. Pneumoni
Permin, H., Johansen, Helle Krogh & Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 6259-6260
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.
Høiby, Niels, Johansen, Helle Krogh, Moser, C., Song, Z., Ciofu, Oana & Kharazmi, A., 2001, In: Microbes and Infection. 3, 1, p. 23-35 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pseudomonas mendocina as a cause of chronic infective endocarditis in a patient with situs inversus
Johansen, Helle Krogh, Kjeldsen, K. & Høiby, Niels, 2001, In: Clinical Microbiology and Infection. 7, p. 650-652
Research output: Contribution to journal › Journal article › Research › peer-review
2000
Published
Effects of Radix angelicae sinensis and Shuanghuanglian on a rat model of chronic Pseudomonas aeruginosa pneumonia
Song, Z. J., Johansen, Helle Krogh, Moser, C., Faber, V., Kharazmi, A., Rygaard, J. & Høiby, Niels, 2000, In: Chinese Medical Sciences Journal. 15(2), p. 83-88
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Routine versus selective antifungal administration for control of fungal infections in patients with cancer (Cochrane Review)
Gøtzsche, P. C. & Johansen, Helle Krogh, 2000, The Cochrane Library, Issue 2. Oxford: Update software, p. -
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
Published
The Copenhagen Study Group on antibiotics in sweat: Excretion of beta-lactam antibiotics in sweat - a neglected mechanism for development of antibiotic resistance?
Høiby, Niels, Pers, C., Johansen, Helle Krogh & Hansen, H., 2000, In: Antimicrobial Agents and Chemotherapy. 44, p. 2855-57
Research output: Contribution to journal › Journal article › Research › peer-review
1999
Published
Activation of the immune defence in blood and lung after ginseng treatment in a rat model with chronic Pseudomonas aeruginosa pneumonia
Song, Z. J., Wu, H., Kharazmi, A., Faber, V., Moser, C., Johansen, Helle Krogh & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 70-70
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Immunomodulatory properties of ginseng. Effects on P. aeruginosa lung infection
Song, Z. J., Kharazmi, A., Wu, H., Moser, C., Johansen, Helle Krogh, Faber, V. & Høiby, Niels, 1999, In: Clinical Microbiology and Infection. 5, p. 537-538
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Problems in the design and reporting of trials of antifungal agents encountered during meta-analysis
Johansen, Helle Krogh & Gøtzsche, P. C., 1999, In: JAMA - Journal of the American Medical Association. 282, p. 1752-9
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Randomised trial of pivampicillin plus pivmecillinam vs. pivampicillin in children and young adults with chronic obstructive pulmonary disease and infection with Haemophilus influenzae
Johansen, Helle Krogh, Børch, K., Espersen, F., Koch, C. & Høiby, Niels, 1999, In: Current Medical Research and Opinion. 15(4), p. 300-309
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Rat model of chronic Pseudomonas aeruginosa lung infection
Johansen, Helle Krogh & Høiby, Niels, 1999, Handbook of animal models of infection. Academic Press, p. 517-526
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
1998
Published
Effect of ginseng treatment on neutrophil chemiluminescence and IgG subclasses in a rat model of chronic Pseudomonas aeruginosa pneumonia
Song, Z., Kharazmi, A., Wu, H., Moser, C., Johansen, Helle Krogh, Faber, V., Rygaard, J. & Høiby, Niels, 1998, In: Clinical and Vaccine Immunology. 5, p. 882-887
Research output: Contribution to journal › Journal article › Research › peer-review
1997
Published
Antifungal prophylactic or empiric therapy vs. placebo or no treatment in cancer patients with neutropenia
Gøtzsche, P. C. & Johansen, Helle Krogh, 1997, Infectious Diseases Module of the Cochrane Database of Systematic Reviews. Oxford: The Cochrane Collaboration, Issue 2
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
Published
Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice
Moser, Claus Ernst, Johansen, Helle Krogh, Song, Z., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1997, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 105, 11, p. 838-42 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia
Gøtzsche, P. C. & Johansen, Helle Krogh, 1997, In: BMJ. British Medical Journal (International Ed.). 314, p. 1238-1244
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia. A new prophylactic principle
Johansen, Helle Krogh, Cryz, S. J., Hougen, H. P., Moser, Claus Ernst & Høiby, Niels, 1997, In: Behring Institute Mitteilungen. 98, p. 269-73 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1996
Published
Interferon-gamma (IFN-gamma) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats
Johansen, Helle Krogh, Hougen, H. P., Rygaard, J. & Høiby, Niels, 1996, In: Clinical and Experimental Immunology. 103, 2, p. 212-8 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics.
Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh, Bender Koch, Christian & Høiby, Niels, 1996, In: Clinical Microbiology and Infection. 2, 2, p. 91-98 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis.
Høiby, Niels, Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh & Koch, C., 1996, In: Pediatric Infectious Disease Journal. 15, 8, p. 738-43 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1995
Published
Experimental chronic Pseudomonas aeruginosa lung infection in rats. Non-specific stimulation with LPS reduces lethality as efficiently as specific immunization
Lange, Kai, Hougen, H. P., Høiby, Niels, Fomsgaard, A., Rygaard, J. & Johansen, Helle Krogh, 1995, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 103, 5, p. 367-74 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia in rats
Johansen, Helle Krogh, Hougen, H. P., Cryz, S. J., Rygaard, J. & Høiby, Niels, 1995, In: American Journal of Respiratory and Critical Care Medicine. 152, 4 Pt 1, p. 1337-46 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1994
Published
Immunization with Pseudomonas aeruginosa vaccines and adjuvant can modulate the type of inflammatory response subsequent to infection
Johansen, Helle Krogh, Espersen, F., Cryz, S. J., Hougen, H. P., Fomsgaard, A., Rygaard, J. & Høiby, Niels, 1994, In: Infection and Immunity. 62, 8, p. 3146-55 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1993
Published
Chronic Pseudomonas aeruginosa lung infection in normal and athymic rats
Johansen, Helle Krogh, Espersen, F., Pedersen, S. S., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1993, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 101, 3, p. 207-225 19 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1991
Published
Manzinellaforgiftning kompliceret med streptokokpharyngitis og impetigo
Bygbjerg, Ib Christian & Johansen, Helle Krogh, 30 Dec 1991, In: Ugeskrift for Laeger. 154, 1, p. 27-8 2 p.
Research output: Contribution to journal › Journal article › Research › peer-review

ID: 8804

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Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model
Research output: Contribution to journal › Journal article › Research › peer-review
Published
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Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry
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Published
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The small RNA ErsA of Pseudomonas aeruginosa contributes to biofilm development and motility through post-transcriptional modulation of AmrZ
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Published

Helle Krogh Johansen

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Clinical Microbiology