Helle Krogh Johansen
Clinical Professor
- 2024
- Published
Adaptive Evolution of Pseudomonas aeruginosa in Human Airways Shows Phenotypic Convergence Despite Diverse Patterns of Genomic Changes
Espaillat, A., Colque, C. A., Rago, D., La Rosa, R., Molin, S. & Johansen, Helle Krogh, 2024, In: MOLECULAR BIOLOGY AND EVOLUTION . 41, 2, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance
Laborda, P., Lolle, S., Hernando-Amado, S., Alcalde-Rico, M., Aanæs, Kasper, Martínez, J. L., Molin, S. & Johansen, Helle Krogh, 2024, In: Nature Communications. 15, 1, 12 p., 2584.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting the primary infection source of Escherichia coli bacteremia using virulence-associated genes
Ilsby, C. S., Hertz, Frederik Boëtius, Westh, Henrik T., Monk, J., Worning, P., Johansen, Helle Krogh, Hansen, Katrine Hartung & Pinholt, M., 2024, In: European Journal of Clinical Microbiology and Infectious Diseases. 43, 4, p. 641-648 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ventriculostomy-associated infection (VAI) in patients with acute brain injury—a retrospective study
Nielsen, P., Olsen, M. H., Willer-Hansen, R. S., Hauerberg, J., Johansen, Helle Krogh, Andersen, A. B., Knudsen, J. D. & Møller, Kirsten, 2024, In: Acta Neurochirurgica. 166, 1, 10 p., 128.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
A Dedicated Mycosis Flask Increases the Likelihood of Identifying Candidemia Sepsis
Ahlström, M. G., Antsupova, V. S., Pedersen, M., Johansen, Helle Krogh, Hansen, D. S. & Knudsen, I. J. D., 2023, In: Journal of Fungi. 9, 4, 15 p., 441.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination
Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup, Pressler, T., Johansen, Helle Krogh & Kolpen, Mette, 2023, In: APMIS. 131, 8, p. 419-425Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhalation devices and inhaled corticosteroids particle size influence on severe pneumonia in patients with chronic obstructive pulmonary disease: a nationwide cohort study
Heerfordt, C. K., Rønn, C., Harboe, Zitta F B Barrella, Ingebrigtsen, T. S., Svorre Jordan, A., Wilcke, Jon Torgny Rostrup, Bonnesen, B., Biering-Sørensen, Tor, Sørensen, Rikke, Holler, J. G., Itenov, Theis Skovsgaard, Johansen, Helle Krogh, Sivapalan, P., Eklöf, J. & Jensen , Jens-Ulrik Stæhr , 2023, In: BMJ Open Respiratory Research. 10, 1, 10 p., e001814. .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term evolution of antibiotic tolerance in Pseudomonas aeruginosa lung infections
Ghoul, M., Andersen, Sandra Breum, Marvig, R. L., Johansen, Helle Krogh, Jelsbak, L., Molin, S., Perron, G. & Griffin, A. S., 2023, In: Evolution Letters. 7, 6, p. 389–400 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Achromobacter spp. in a Cohort of Non-Selected Pre-and Post-Lung Transplant Recipients
Crone, C. G., Rezahosseini, O., Schultz, H. H. L., Qvist, T., Johansen, Helle Krogh, Nielsen, Susanne Dam & Perch, Michael, 2022, In: Pathogens. 11, 2, 181.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic criteria of CNS infection in patients with external ventricular drainage after traumatic brain injury: a pilot study
Willer-Hansen, R. S., Olsen, M. H., Hauerberg, J., Johansen, Helle Krogh, Andersen, Å. B. & Møller, Kirsten, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 507-515 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inter-species interactions alter antibiotic efficacy in bacterial communities
Bottery, M. J., Matthews, J. L., Wood, A. J., Johansen, Helle Krogh, Pitchford, J. W. & Friman, V. P., 2022, In: ISME Journal. 16, p. 812–821Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams
Colque, C. A., albarracín Orio, A. G., Tomatis, P. E., Dotta, G., Moreno, D. M., Hedemann, L. G., Hickman, R. A., Sommer, L. M., Feliziani, S., Moyano, A. J., Bonomo, R. A., Johansen, Helle Krogh, Molin, S., Vila, A. J. & Smania, A. M., 2022, In: mBio. 13, 5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance
Goltermann, L., Andersen, Kasper Langebjerg, Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1594-1601Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance: author's response
Goltermann, L., Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1667-1668 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
New concepts in antimicrobial resistance in cystic fibrosis respiratory infections
Drevinek, P., Canton, R., Johansen, Helle Krogh, Hoffman, L., Coenye, T., Burgel, P. & Davies, J. C., 2022, In: Journal of Cystic Fibrosis. 21, 6, p. 937-945 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease
Eklöf, J., Misiakou, M. A., Sivapalan, P., Armbruster, K., Browatzki, A., Nielsen, T. L., Lapperre, T. S., Andreassen, H. F., Janner, J., Ulrik, C. S., Gabrielaite, M., Johansen, H. K., Jensen, A., Nielsen, T. V., Hertz, F. B., Ghathian, K., Calum, H., Wilcke, T., Seersholm, N., Jensen, J. U. S. & 1 others, , 2022, In: Clinical Microbiology and Infection. 28, 7, p. 990-995 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution
La Rosa, R., Johansen, Helle Krogh & Molin, S., 2022, In: Antibiotics. 11, 3, 419.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs
Luján, A. M., Paterson, S., Hesse, E., Sommer, L. M., Marvig, R. L., Sharma, M. D., Alseth, E. O., Ciofu, Oana, Smania, A. M., Molin, S., Johansen, Helle Krogh & Buckling, A., 2022, In: Nature Ecology and Evolution. 6, p. 979–988Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial
Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., Rades, T. & 17 others, , 2022, In: Clinical and Translational Medicine. 12, 5, e790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of inhaled antibiotics among Danish patients with cystic fibrosis
Møller, R., Nielsen, B. U., Faurholt-Jepsen, D., Katzenstein, T. L., Skov, M., Philipsen, L. K. D., Pressler, T., Johansen, Helle Krogh & Qvist, T., 2022, In: Pediatric Pulmonology. 57, 7, p. 1726-1734 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Achromobacter spp. genetic adaptation in cystic fibrosis
Gabrielaite, M., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marvig, R. L., 2021, In: Microbial genomics. 7, 7, 13 p., 000582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
Rossi, E., La Rosa, R., Bartell, J. A., Marvig, R. L., Haagensen, J. A. J., Sommer, L. M., Molin, S. & Johansen, Helle Krogh, 2021, In: Nature Reviews Microbiology. 19, p. 331–342Research output: Contribution to journal › Review › Research › peer-review
- Published
A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19
Backer, Vibeke, Sjöbring, U., Sonne, J., Weiss, A., Hostrup, Morten, Johansen, Helle Krogh, Becker, V., Sonne, D. P., Balchen, T., Jellingsø, M. & Sommer, M. O. A., 2021, In: The Lancet Regional Health - Europe. 4, 8 p., 100084.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A retrospective review of Achromobacter species and antibiotic treatments in patients with primary ciliary dyskinesia
Holgersen, M. G., Marthin, J. K., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: Chronic Respiratory Disease. 18Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adaptive interactions of achromobacter spp. With pseudomonas aeruginosa in cystic fibrosis chronic lung co-infection
Sandri, A., Haagensen, J. A. J., Veschetti, L., Johansen, Helle Krogh, Molin, S., Malerba, G., Signoretto, C., Boaretti, M. & Lleo, M. M., 2021, In: Pathogens. 10, 8, 12 p., 978.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial re-colonization occurs early after lung transplantation in cystic fibrosis patients
Holm, A. E., Schultz, H. H. L., Johansen, Helle Krogh, Pressler, T., Lund, T. K., Iversen, M. & Perch, Michael, 2021, In: Journal of Clinical Medicine. 10, 6, 11 p., 1275.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-delivery of ciprofloxacin and colistin using microcontainers for bacterial biofilm treatment
Birk, S. E., Mazzoni, C., Mobasharah Javed, M., Borre Hansen, M., Johansen, Helle Krogh, Anders Juul Haagensen, J., Molin, S., Hagner Nielsen, L. & Boisen, A., 2021, In: International Journal of Pharmaceutics. 599, 120420.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Compensatory evolution of Pseudomonas aeruginosa’s slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis
La Rosa, R., Rossi, E., Feist, A. M., Johansen, Helle Krogh & Molin, S., 2021, In: Nature Communications. 12, 1, 3186.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-throughput dilution-based growth method enables time-resolved exo-metabolomics of Pseudomonas putida and Pseudomonas aeruginosa
Pedersen, B. H., Gurdo, N., Johansen, Helle Krogh, Molin, S., Nikel, P. I. & La Rosa, R., 2021, In: Microbial Biotechnology. 14, 5, p. 2214-2226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
International BEAT-PCD consensus statement for infection prevention and control for primary ciliary dyskinesia in collaboration with ERN-LUNG PCD Core Network and patient representatives
Marthin, J. K., Lucas, J. S., Boon, M., Casaulta, C., Crowley, S., Destouches, D. M. S., Eber, E., Escribano, A., Haarman, E., Hogg, C., Maitre, B., Marsh, G., Martinu, V., Moreno-Galdó, A., Mussaffi, H., Omran, H., Pohunek, P., Rindlisbacher, B., Robinson, P., Snijders, D. & 4 others, , 2021, In: ERJ Open Research. 7, 3, 14 p., 00301-2021.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Omics-based tracking of Pseudomonas aeruginosa persistence in "eradicated" cystic fibrosis patients
Bartell, J. A., Sommer, L. M., Marvig, R. L., Skov, M., Pressler, T., Molin, S. & Johansen, Helle Krogh, 2021, In: The European Respiratory Journal. 57, 4, 2000512.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transmission and Antibiotic Resistance of Achromobacter in Cystic Fibrosis
Gabrielaite, M., Bartell, J. A., Nørskov-Lauritsen, N., Pressler, T., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marviga, R. L., 2021, In: Journal of Clinical Microbiology. 59, 4, e02911-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Update 2016–2018 of the Nationwide Danish Fungaemia Surveillance Study: Epidemiologic Changes in a 15-Year Perspective
Risum, M., Astvad, K., Johansen, Helle Krogh, Schønheyder, H. C., Rosenvinge, F., Knudsen, J. D., Hare, R. K., Datcu, R., Røder, B. L., Antsupova, V. S., Kristensen, L., Gertsen, J. B., Møller, J. K., Dzajic, E., Søndergaard, T. S. & Arendrup, Maiken Cavling, 2021, In: Journal of Fungi. 7, 6, 16 p., 491.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms
Birk, S. E., Haagensen, J. A. J., Johansen, Helle Krogh, Molin, S., Nielsen, L. H. & Boisen, A., May 2020, In: Advanced Healthcare Materials. 9, 10, 10 p., 1901779.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypermutator Pseudomonas Aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients
Colque, C. A., Albarracín Orio, A. G., Feliziani, S., Marvig, R. L., Tobares, A. R., Johansen, Helle Krogh, Molin, S. & Smania, A. M., Apr 2020, In: Antimicrobial Agents and Chemotherapy. 64, 5, p. e02142-19Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nanograss sensor for selective detection of Pseudomonas aeruginosa by pyocyanin identification in airway samples
Alatraktchi, F. A. Z. A., Dimaki, M., Støvring, N., Johansen, Helle Krogh, Molin, S. & Svendsen, W. E., Mar 2020, In: Analytical Biochemistry. 593, 6 p., 113586.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypermutation as an Evolutionary Mechanism for Achromobacter Xylosoxidans in Cystic Fibrosis Lung Infection
Veschetti, L., Sandri, A., Johansen, Helle Krogh, Lleò, M. M. & Malerba, G., Feb 2020, In: Pathogens. 9, 2, 10 p., 72.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new device to prevent contamination of nasal swabs by Staphylococcus aureus in acute rhinosinutitis
Kirkegaard Kiaer, E., Hakansson, K., Orntoft, S., Bartels, Mette Damkjær, Johansen, Helle Krogh & von Buchwald, Christian, 2020, In: Rhinology Online. 3, p. 39-44Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments
Sommer, L. M., Johansen, Helle Krogh & Molin, S., 2020, In: Microbial Genomics. 6, 5, p. 1-6 6 p., 000370.Research output: Contribution to journal › Review › Research › peer-review
- Published
Azole-Resistant Aspergillus fumigatus Among Danish Cystic Fibrosis Patients: Increasing Prevalence and Dominance of TR34/L98H
Risum, M., Hare, R. K., Gertsen, J. B., Kristensen, L., Johansen, Helle Krogh, Helweg-Larsen, J., Abou-Chakra, N., Pressler, T., Skov, M., Jensen-Fangel, S. & Arendrup, Maiken Cavling, 2020, In: Frontiers in Microbiology. 11, 10 p., 1850.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment
Bartell, J. A., Cameron, D. R., Mojsoska, B., Haagensen, J. A. J., Pressler, T., Sommer, L. M., Lewis, K., Molin, S. & Johansen, Helle Krogh, 2020, In: PLOS Pathogens. 16, 12 December, e1009112.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene loss and acquisition in lineages of pseudomonas aeruginosa evolving in cystic fibrosis patient airways
Gabrielaite, M., Johansen, Helle Krogh, Molin, S., Nielsen, Finn Cilius & Marvig, R. L., 2020, In: mBio. 11, 5, p. 1-16 16 p., e02359-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs
Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.Research output: Contribution to journal › Letter › Research › peer-review
- 2019
- Published
Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate
Halfon, Y., Jimenez-Fernandez, A., La Rosa, R., Espinosa Portero, R., Johansen, Helle Krogh, Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S. & Yonath, A., 29 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22275-22281 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients
La Rosa, R., Johansen, Helle Krogh & Molin, S., 2019, In: Metabolites. 9, 10, 15 p., 234.Research output: Contribution to journal › Review › Research › peer-review
- Published
Evolutionary highways to persistent bacterial infection
Bartell, J. A., Sommer, L. M., Haagensen, J. A. J., Loch, A., Espinosa, R., Molin, S. & Johansen, Helle Krogh, 2019, In: Nature Communications. 10, 1, 13 p., 629.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis
Burgener, E. B., Sweere, J. M., Bach, M. S., Secor, P. R., Haddock, N., Jennings, L. K., Marvig, R. L., Johansen, Helle Krogh, Rossi, E., Cao, X., Tian, L., Nedelec, L., Molin, S., Bollyky, P. L. & Milla, C. E., 2019, In: Science Translational Medicine. 11, 488, 12 p., eaau9748.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reconciling Antimicrobial Susceptibility Testing and Clinical Response in Antimicrobial Treatment of Chronic Cystic Fibrosis Lung Infections
Waters, V. J., Kidd, T. J., Canton, R., Ekkelenkamp, M. B., Johansen, Helle Krogh, LiPuma, J. J., Bell, S. C., Elborn, J. S., Flume, P. A., VanDevanter, D. R., Gilligan, P. & Antimicrobial Resistance International Working Group in Cystic Fibrosis , A. R. I. W. G. I. C. F., 2019, In: Clinical Infectious Diseases. 69, 10, p. 1812-1816Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia
Scott, W. K., Medie, F. M., Ruffin, F., Sharma-Kuinkel, B. K., Cyr, D. D., Guo, S., Dykxhoorn, D. M., Skov, R. L., Bruun, N. E., Dahl, A., Lerche, C. J., Petersen, A., Larsen, A. R., Lauridsen, T. K., Johansen, H. K., Ullum, H., Sørensen, E., Hassager, C., Bundgaard, H., Schønheyder, H. C. & 9 others, , Oct 2018, In: P L o S Genetics. 14, 10, p. 1-22 e1007667.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Genetic Susceptibility to Native Valve Staphylococcus aureus Endocarditis in Patients With S. aureus Bacteremia: Genome-Wide Association Study
Moreau, K., Clemenceau, A., Le Moing, V., Messika-Zeitoun, D., Andersen, P. S., Bruun, Niels Eske, Skov, R. L., Couzon, F., Bouchiat, C., Erpelding, M. L., van Belkum, A., Bossé, Y., Duval, X., Vandenesch, F., The French VIRSTA-AEPEI, COFRASA Study Groups and the Danish DANSAB Study Group, T. F. V. C. S. G. A. T. D. D. S. G., Johansen, Helle Krogh, Hassager, Christian & Ullum, H., 4 Apr 2018, In: Frontiers in Microbiology. 9, p. 1-11 640.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8804
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2008
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Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model
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Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry
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168
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The small RNA ErsA of Pseudomonas aeruginosa contributes to biofilm development and motility through post-transcriptional modulation of AmrZ
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