Helena Safavi

Helena Safavi

Safavi Group


  1. 2020
  2. Published

    A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

    Xiong, X., Menting, J. G., Disotuar, M. M., Smith, N. A., Delaine, C. A., Ghabash, G., Agrawal, R., Wang, X., He, X., Fisher, S. J., MacRaild, C. A., Norton, R. S., Gajewiak, J., Forbes, B. E., Smith, B. J., Safavi, Helena, Olivera, B., Lawrence, M. C. & Chou, D. H. C., 2020, In : Nature Structural and Molecular Biology. 27, p. 615-624

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research

    Bjørn-Yoshimoto, Walden, Ramiro, Iris Bea, Yandell, M., McIntosh, J. M., Olivera, B. M., Ellgaard, Lars & Safavi, Helena, 2020, In : Biomedicines. 8, 8, 22 p., 235.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Transcriptomic Profiling Reveals Extraordinary Diversity of Venom Peptides in Unexplored Predatory Gastropods of the Genus Clavus

    Lu, A., Watkins, M., Li, Q., Robinson, S. D., Concepcion, G. P., Yandell, M., Weng, Z., Olivera, B. M., Safavi, Helena & Fedosov, A. E., 2020, In : Genome Biology and Evolution. 12, 5, p. 684-700 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2019
  6. Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

    Ahorukomeye, P., Disotuar, M. M., Gajewiak, J., Karanth, S., Watkins, M., Robinson, S. D., Flórez Salcedo, P., Smith, N. A., Smith, B. J., Schlegel, A., Forbes, B. E., Olivera, B., Hung-Chieh Chou, D. & Safavi, Helena, 2019, In : eLife. 8, 28 p., e41574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways

    Safavi, Helena, Brogan, S. E. & Olivera, B. M., 2019, In : Journal of Proteomics. 190, p. 12-20 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

    Kjelgaard, Lau Dalby, Foged, M. M., Albert, A., Bertelsen, A. B., Søltoft, Cecilie Lützen, Robinson, S. D., Petersen, S. V., Purcell, A. W., Olivera, B. M., Norton, R. S., Vasskog, T., Safavi, Helena, Teilum, Kaare & Ellgaard, Lars, 2019, In : The Journal of Biological Chemistry. 294, 22, p. 8745-8759

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2018
  10. Conopeptides promote itch through human itch receptor hMgprX1

    Espino, S. S., Robinson, S. D., Safavi, Helena, Gajewiak, J., Yang, W., Olivera, B. M. & Liu, Q., 2018, In : Toxicon. 154, p. 28-34 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Discovery of Novel Conotoxin Candidates Using Machine Learning

    Li, Q., Watkins, M., Robinson, S. D., Safavi, Helena & Yandell, M., 2018, In : Toxins. 10, 12, 503.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Ero1-Mediated Reoxidation of Protein Disulfide Isomerase Accelerates the Folding of Cone Snail Toxins

    O'Brien, H., Kanemura, S., Okumura, M., Baskin, R. P., Bandyopadhyay, P. K., Olivera, B. M., Ellgaard, Lars, Inaba, K. & Safavi, Helena, 2018, In : International Journal of Molecular Sciences . 19, 11, 15 p., 3418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Evolutionary Adaptations to Cysteine-rich Peptide Folding

    Safavi, Helena, Foged, M. M. & Ellgaard, Lars, 2018, Oxidative Folding of Proteins: Basic Principles, Cellular Regulation and Engineering . Feige, M. J. (ed.). Royal Society of Chemistry, p. 99-128 30 p. (Chemical Biology, Vol. 9).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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