Hans K Hasselbalch

Hans K Hasselbalch

Clinical Professor

Member of:

  • Internal Medicine: Haematology


Publication year:
All
1 - 133 out of 133Page size: 500
  1. 2024
  2. Published

    JAK2V617F drives gut microbiota differences in patients with myeloproliferative neoplasms

    Eickhardt-Dalbøge, C. S., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Andersen, L. O., Lilje, B., Larsen, Morten Kranker, Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Sørensen, A. L., Ellervik, Christina, Olsen, L. R., Christensen, J. J. E., Nielsen, X. C., Hasselbalch, Hans Carl & Ingham, A. C., 2024, In: European Journal of Haematology. 112, 5, p. 776-787 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    CHIP-JAK2V617F, chronic inflammation, abnormal megakaryocyte morphology, organ failure, and multimorbidties

    Hasselbalch, Hans Carl, Kristiansen, M. H., Kjær, L., Skov, V., Larsen, Morten Kranker, Ellervik, Christina & Wienecke, Troels, 2024, In: Blood advances. 8, 3, p. 681-682 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  4. Published

    Neutrophil-to-lymphocyte ratio and all-cause mortality with and without myeloproliferative neoplasms-a Danish longitudinal study

    Larsen, Morten Kranker, Skov, V., Kjær, L., Eickhardt-Dalbøge, C. S., Knudsen, T. A., Kristiansen, M. H., Sørensen, A. L., Wienecke, Troels, Andersen, M., Ottesen, J. T., Gudmand-Høyer, J., Snyder, J. A., Andersen, M. P., Torp-Pedersen, Christian, Poulsen, Henrik Enghusen, Stiehl, T., Hasselbalch, Hans Carl & Ellervik, Christina, 2024, In: Blood Cancer Journal. 14, 1, 12 p., 28.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2023
  6. Published

    Serum levels of IL-4, IL-13 and IL-33 in patients with age-related macular degeneration and myeloproliferative neoplasms

    Gotfredsen, K., Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 11 Mar 2023, In: Scientific Reports. 13, 1, p. 4077 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A novel integrated biomarker index for the assessment of hematological responses in MPNs during treatment with hydroxyurea and interferon-alpha2

    Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Ellervik, Christina, Larsen, Morten Kranker, Kjær, L., Skov, V., Hasselbalch, Hans Carl & Ottesen, J. T., 2023, In: Cancer Medicine. 12, 4, p. 4218-4226

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    An arginase1- and PD-L1-derived peptide-based vaccine for myeloproliferative neoplasms: A first-in-man clinical trial

    Grauslund, J. H., Holmström, M. O., Martinenaite, E., Lisle, T. L., Glöckner, H. J., Fassi, Daniel El , Klausen, U., Mortensen, R. E. J., Jørgensen, N., Kjær, L., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1117466.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Case Report: First longitudinal study of a patient with CALR positive clonal hematopoiesis of indeterminate potential developing into pre-fibrotic myelofibrosis

    Kjær, L., Skov, V., Larsen, Morten Kranker, Boklund, T. I., Andersen, M., Kefala, Maria, Knudsen, T. A., Schjellerup Eickhardt-Dalbøge, C., Stiehl, T., Gudmand-Høyer, J., Snyder, J., Holmström, M., Andersen, M. H., Ottesen, J. T., Ellervik, Christina & Hasselbalch, Hans Carl, 2023, In: Frontiers in Oncology. 13, 8 p., 1176173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Elevated white blood cell counts in ischemic stroke patients are associated with increased mortality and new vascular events

    Vo, T. P., Kristiansen, M. H., Hasselbalch, Hans Carl & Wienecke, Troels, 2023, In: Frontiers in Neurology. 14, 8 p., 1232557.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Event-free survival in patients with polycythemia vera treated with ropeginterferon alfa-2b versus best available treatment

    the PROUD-PV Study Group, T. P. S. G., 2023, In: Leukemia. 37, 10, p. 2129-2132 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  12. Published

    High JAK2V617F variant allele frequency is associated with coronary artery but not aortic valve calcifications in patients with Philadelphia-negative myeloproliferative neoplasms

    Solli, C. N., Chamat-Hedemand, S., Elming, H., Ngo, A., Kjær, L., Skov, V., Sørensen, A. L., Ellervik, Christina, Hasselbalch, Hans Carl & Bruun, Niels Eske, 2023, In: European Journal of Haematology. 111, 3, p. 400-406 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Interferon alpha-2 treatment reduces circulating neutrophil extracellular trap levels in myeloproliferative neoplasms

    Massarenti, Laura, Knudsen, T. A., Enevold, Christian, Skov, V., Kjær, L., Larsen, M. K., Larsen, T. S., Hansen, D. L., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, 2023, In: British Journal of Haematology. 202, 2, p. 318-327 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    JAK2V617F mutation is highly prevalent in patients with ischemic stroke: a case-control study

    Kristiansen, M. H., Kjær, L., Skov, V., Larsen, Morten Kranker, Ellervik, Christina, Hasselbalch, Hans Carl & Wienecke, Troels, 2023, In: Blood advances. 7, 19, p. 5825-5834 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Pronounced gut microbiota signatures in patients with JAK2V617F-positive essential thrombocythemia

    Eickhardt-Dalbøge, C. S., Ingham, A. C., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Andersen, L. O., Larsen, Morten Kranker, Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Ellervik, Christina, Olsen, L. R., Hasselbalch, Hans Carl, Elmer Christensen, J. J. & Nielsen, X. C., 2023, In: Microbiology Spectrum. 11, 5, 19 p., e0066223.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Revisiting Circulating Extracellular Matrix Fragments as Disease Markers in Myelofibrosis and Related Neoplasms

    Hasselbalch, Hans Carl, Junker, P., Skov, V., Kjær, L., Knudsen, T. A., Larsen, Morten Kranker, Holmström, M. O., Andersen, Mads Hald, Jensen, C., Karsdal, M. A. & Willumsen, N., 2023, In: Cancers. 15, 17, 47 p., 4323.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    The gut microbiota in patients with polycythemia vera is distinct from that of healthy controls and varies by treatment

    Eickhardt-dalbøge, C. S., Ingham, A. C., Andersen, L. O., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Larsen, M. K., Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Ellervik, C., Olsen, L. R., Hasselbalch, Hans Carl, Nielsen, X. C. & Christensen, J. J. E., 2023, In: Blood advances. 7, 13, p. 3326-3337 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Therapeutic cancer vaccination against mutant calreticulin in myeloproliferative neoplasms induces expansion of specific T cells in the periphery but specific T cells fail to enrich in the bone marrow

    Holmström, M. O., Andersen, M., Traynor, S., Ahmad, S. M., Lisle, T. L., Handlos Grauslund, J., Skov, V., Kjær, L., Ottesen, J. T., Gjerstorff, M. F., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1240678.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2022
  20. Published

    Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers

    Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, Jun 2022, In: PLoS ONE. 17, 6, 16 p., e0269960.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Long-term outcomes of polycythemia vera patients treated with ropeginterferon Alfa-2b

    PROUD-PV Study Grp, P. S. G., May 2022, In: Leukemia. 36, 5, p. 1408-1411 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  22. Published

    Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

    Gigoux, M., Holmström, M. O., Zappasodi, R., Park, J. J., Pourpe, S., Bozkus, C. C., Mangarin, L. M. B., Redmond, D., Verma, S., Schad, S., George, M. M., Venkatesh, D., Ghosh, A., Hoyos, D., Molvi, Z., Kamaz, B., Marneth, A. E., Duke, W., Leventhal, M. J., Jan, M. & 23 others, Ho, V. T., Hobbs, G. S., Knudsen, T. A., Skov, V., Kjær, L., Larsen, T. S., Hansen, D. L., Lindsley, R. C., Hasselbalch, Hans Carl, Grauslund, J. H., Lisle, T. L., Met, Özcan, Wilkinson, P., Greenbaum, B., Sepulveda, M. A., Chan, T., Rampal, R., Andersen, Mads Hald, Abdel-Wahab, O., Bhardwaj, N., Wolchok, J. D., Mullally, A. & Merghoub, T., 2022, In: Science Translational Medicine. 14, 649, eaba4380.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Clonal haematopoiesis of indeterminate potential and impaired kidney function—A Danish general population study with 11 years follow-up

    Larsen, Morten Kranker, Skov, V., Kjær, L., Møller-Palacino, N. A., Pedersen, R. K., Andersen, M., Ottesen, J. T., Cordua, S., Poulsen, Henrik Enghusen, Dahl, Morten, Knudsen, T. A., Eickhardt-Dalbøge, C. S., Koschmieder, S., Pedersen, K. M., Çolak, Y., Bojesen, Stig Egil, Nordestgaard, Børge, Stiehl, T., Hasselbalch, Hans Carl & Ellervik, Christina, 2022, In: European Journal of Haematology. 109, 5, p. 576-585 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Coronary artery- and aortic valve calcifications in patients with Philadelphia-negative myeloproliferative neoplasms

    Solli, C. N., Chamat-Hedemand, S., Elming, H., Ngo, A., Kjær, L., Skov, V., Sørensen, A. L., Ellervik, Christina, Fuchs, A., Sigvardsen, P. E., Kühl, J. T., Kofoed, Klaus Fuglsang, Nordestgaard, Børge, Hasselbalch, Hans Carl & Bruun, Niels Eske, 2022, In: International Journal of Cardiology. 364, p. 112-118 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Genomic profiling of a randomized trial of interferon-a vs hydroxyurea in MPN reveals mutation-specific responses

    Knudsen, T. A., Skov, V., Stevenson, K., Werner, L., Duke, W., Laurore, C., Gibson, C. J., Nag, A., Thorner, A. R., Wollison, B., Hansen, D. L., Ellervik, C., Fassi, D. E., de Stricker, K., Ocias, L. F., Brabrand, M., Bjerrum, O. W., Overgaard, U. M., Frederiksen, M., Kristensen, T. K. & 12 others, Kruse, T. A., Thomassen, M., Mourits-Andersen, T., Severinsen, M. T., Stentoft, J., Starklint, J., Neuberg, D. S., Kjaer, L., Larsen, T. S., Hasselbalch, Hans Carl, Lindsley, R. C. & Mullally, A., 2022, In: Blood advances. 6, 7, p. 2107-2119 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Healthcare resource utilization in patients with myeloproliferative neoplasms: A Danish nationwide matched cohort study

    Christensen, S. F., Svingel, L. S., Kjaersgaard, A., Stenling, A., Darvalics, B., Paulsson, B., Andersen, Christen Bertel L, Christiansen, C. F., Stentoft, J., Starklint, J., Severinsen, M. T., Clausen, M. B., Hilsoe, M. H., Hasselbalch, Hans Carl, Frederiksen, H., Mikkelsen, E. M. & Bak, M., 2022, In: European Journal of Haematology. 109, 5, p. 526-541 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms favorably impacts deregulation of oxidative stress genes and antioxidative defense mechanisms

    Skov, V., Thomassen, M., Kjær, L., Ellervik, Christina, Larsen, Morten Kranker, Knudsen, T. A., Kruse, T. A. & Hasselbalch, Hans Carl, 2022, In: PLoS ONE. 17, 6 , e0270669.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Patients With Myeloproliferative Neoplasms Harbor High Frequencies of CD8 T Cell-Platelet Aggregates Associated With T Cell Suppression

    Carnaz Simões, A. M., Holmström, M. O., Aehnlich, P., Rahbech, A., Radziwon-Balicka, A., Zamora, C., Wirenfeldt Klausen, T., Skov, V., Kjær, L., Ellervik, Christina, Fassi, Daniel El , Vidal, S., Hasselbalch, Hans Carl, Andersen, Mads Hald & thor Straten, P., 2022, In: Frontiers in Immunology. 13, 866610.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Patients with MPNs and retinal drusen show signs of complement system dysregulation and a high degree of chronic low-grade inflammation

    Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2022, In: EClinicalMedicine. 43, 101248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Recombinant Interferon-β in the Treatment of Polycythemia Vera and Related Neoplasms: Rationales and Perspectives

    Hasselbalch, Hans Carl, Skov, V., Kjær, L., Larsen, Morten Kranker, Knudsen, T. A., Lucijanić, M. & Kusec, R., 2022, In: Cancers. 14, 22, 5495.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2021
  32. Published

    Forhøjede blodcelletal og vaskulær sygdom med de myeloproliferative neoplasier som modelsygdomme

    Hasselbalch, Hans Carl, Knudsen, T. A., Sørensen, A. L., Christensen, S. F., Larsen, Morten Kranker, Bak, M., El Fassi, D., Cordua, S., Brabrand, M., Thomsen, G., Stentoft, J., Starklint, J., Ellervik, Christina, Wienecke, Troels, Bruun, Niels Eske, Eickhardt-Dalbøge, C. E., Kjær, L. & Skov, V., 18 Oct 2021, In: Ugeskrift for Laeger. 183, 42, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Therapeutic Cancer Vaccination With a Peptide Derived From the Calreticulin Exon 9 Mutations Induces Strong Cellular Immune Responses in Patients With CALR-Mutant Chronic Myeloproliferative Neoplasms

    Handlos Grauslund, J., Holmström, M. O., Jørgensen, N. G., Klausen, U., Weis-Banke, S. E., El Fassi, D., Schöllkopf, C., Clausen, M. B., Gjerdrum, L. M. R., Breinholt, M. F., Kjeldsen, J. W., Hansen, M., Koschmieder, S., Chatain, N., Novotny, G. W., Petersen, J., Kjær, L., Skov, V., Met, Ö., Svane, I. M. & 2 others, Hasselbalch, Hans Carl & Andersen, Mads Hald, 26 Feb 2021, In: Frontiers in Oncology. 11, 17 p., 637420.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis

    Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Ottesen, J. T., 2021, In: European Journal of Haematology. 107, 6, p. 624-633 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Early detection of myeloproliferative neoplasms in a Danish general population study

    Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Kefala, Maria, Gjerdrum, Lise Mette Rahbek, Hasselbalch, Hans Carl & Ellervik, Christina, 2021, In: Leukemia. 35, 9, p. 2706-2709 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Elevated levels of oxidized nucleosides in individuals with the JAK2V617F mutation from a general population study

    Sørensen, A. L., Hasselbalch, Hans Carl, Bjørn, M. E., Nielsen, C. H., Cordua, S., Skov, V., Kjær, L., Poulsen, Henrik Enghusen & Ellervik, Christina, 2021, In: Redox Biology. 41, 101895.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    New Perspectives of Interferon-alpha2 and Inflammation in Treating Philadelphia-negative Chronic Myeloproliferative Neoplasms

    Hasselbalch, Hans Carl & Silver, R. T., 2021, In: HemaSphere. 5, 12, p. 1-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Response to pegylated interferon in a COVID-19 positive male with metastatic jejunal neuroendocrine tumor treated with everolimus

    Frankel, A. E., Yip, W. C., Naik, E. & Hasselbalch, Hans Carl, 2021, In: Clinical Case Reports. 9, 6, e04218.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Response to pegylated interferon in a COVID-19–positive elderly woman with primary myelofibrosis treated with ruxolitinib

    Frankel, A. E., Reddy, R., DeSuza, K. R., Deeb, K., Carlin, A. F., Smith, D., Xie, Y., Naik, E., Silver, R. T. & Hasselbalch, Hans Carl, 2021, In: Clinical Case Reports. 9, 4, p. 2228-2235 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Retinal drusen in patients with chronic myeloproliferative blood cancers are associated with an increased proportion of senescent T cells and signs of an aging immune system

    Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2021, In: Aging. 13, 24, p. 25763—25777

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Smoking impairs molecular response, and reduces overall survival in patients with chronic myeloproliferative neoplasms: A retrospective cohort study

    Sørensen, A. L., Knudsen, T. A., Skov, V., Kjær, L., Holm, N., Ellervik, Christina & Hasselbalch, Hans Carl, 2021, In: British Journal of Haematology. 193, 1, p. 83-92

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The pathobiology of thrombosis, microvascular disease, and hemorrhage in the myeloproliferative neoplasms

    Hasselbalch, Hans Carl, Elvers, M. & Schafer, A. I., 2021, In: Blood. 137, 16, p. 2152-2160 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Tobacco use in the Myeloproliferative neoplasms: symptom burden, patient opinions, and care

    Christensen, S. F., Scherber, R. M., Mazza, G. L., Dueck, A. C., Brochmann, N., Andersen, Christen Bertel L, Hasselbalch, Hans Carl, Mesa, R. A. & Geyer, H. L., 2021, In: BMC Cancer. 21, 1, 13 p., 691.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. 2020
  45. Published

    Smoking, blood cells and myeloproliferative neoplasms: meta-analysis and Mendelian randomization of 2·3 million people

    Jayasuriya, N. A., Kjaergaard, A. D., Pedersen, K. M., Sørensen, A. L., Bak, M., Larsen, M. K., Nordestgaard, Børge, Bojesen, Stig Egil, Çolak, Y., Skov, V., Kjaer, L., Tolstrup, J. S., Hasselbalch, Hans Carl & Ellervik, Christina, Apr 2020, In: British Journal of Haematology. 189, 2, p. 323-334 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Age-related prevalence and clinical significance of neutropenia - isolated or combined with other cytopenias: Real world data from 373 820 primary care individuals

    Palmblad, J., Siersma, Volkert Dirk, Lind, B., Bjerrum, O. W., Hasselbalch, Hans Carl & Andersen, Christen Bertel L, 2020, In: American Journal of Hematology. 95, 5, p. 521-528 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Cancer immune therapy for Philadelphia chromosome-negative chronic myeloproliferative neoplasms

    Holmström, M. O., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2020, In: Cancers. 12, 7, p. 1-21 21 p., 1763.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Data-driven analysis of JAK2V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms

    Pedersen, R. K., Andersen, M., Knudsen, T. A., Sajid, Z., Gudmand-Hoeyer, J., Dam, M. J. B., Skov, V., Kjær, L., Ellervik, Christina, Larsen, T. S., Hansen, D., Pallisgaard, N., Hasselbalch, Hans Carl & Ottesen, J. T., 2020, In: Cancer Medicine. 9, 6, p. 2039-2051

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Evidence of immune elimination, immuno-editing and immune escape in patients with hematological cancer

    Holmström, M. O., Cordua, S., Skov, V., Kjær, L., Pallisgaard, N., Ellervik, Christina, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2020, In: Cancer Immunology, Immunotherapy. 69, p. 315–324

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    Increased oxidative stress with substantial dysregulation of genes related to oxidative stress and DNA repair after laparoscopic colon cancer surgery

    Watt, S. K., Hasselbalch, Hans Carl, Skov, V., Kjær, L., Thomassen, M., Kruse, T. A., Burton, M., Poulsen, Henrik Enghusen & Gögenur, Ismail, 2020, In: Surgical Oncology. 35, p. 71-78 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Loss-of-function polymorphism in IL6R reduces risk of JAK2V617F somatic mutation and myeloproliferative neoplasm: A Mendelian randomization study

    Pedersen, K. M., Çolak, Y., Ellervik, Christina, Hasselbalch, Hans Carl, Bojesen, Stig Egil & Nordestgaard, Børge, 2020, In: EClinicalMedicine. 21, 100280.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Myeloproliferative blood cancers as a human neuroinflammation model for development of Alzheimer's disease: evidences and perspectives

    Hasselbalch, Hans Carl, Skov, V., Kjær, L., Sørensen, Torben Lykke, Ellervik, Christina & Wienecke, Troels, 2020, In: Journal of Neuroinflammation. 17, 13 p., 248.

    Research output: Contribution to journal › Review › Research › peer-review

  53. Published

    Ocular Manifestations in Patients with Philadelphia-Negative Myeloproliferative Neoplasms

    Liisborg, C., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2020, In: Cancers. 12, 3, 14 p., 573.

    Research output: Contribution to journal › Review › Research › peer-review

  54. Published

    Patients with myeloproliferative neoplasms and high levels of systemic inflammation develop age-related macular degeneration

    Liisborg, C., Krogh Nielsen, M., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2020, In: EClinicalMedicine. 26, 8 p., 100526.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Rationaler for behandling med januskinase 1/2-hæmning af svært syge patienter med COVID-19-pneumoni

    Hasselbalch, Hans Carl, Poulsen, Anne, Skov, V., Kjær, L., Nielsen, C. H. & Poulsen, T. D., 2020, In: Ugeskrift for Laeger. 182, 25, 9 p., V04200234.

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    Ropeginterferon Alfa-2b: Efficacy and Safety in Different Age Groups

    Gisslinger, H., Klade, C., Georgiev, P., Krochmalczyk, D., Gercheva-kyuchukova, L., Egyed, M., Rossiev, V., Dulicek, P., Illes, A., Pylypenko, H., Sivcheva, L., Mayer, J., Yablokova, V., Krejcy, K., Hasselbalch, Hans Carl, Kralovics, R. & Kiladjian, J., 2020, In: HemaSphere. 4, 6, 4 p., e485.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study

    Gisslinger, H., Klade, C., Georgiev, P., Krochmalczyk, D., Gercheva-Kyuchukova, L., Egyed, M., Rossiev, V., Dulicek, P., Illes, A., Pylypenko, H., Sivcheva, L., Mayer, J., Yablokova, V., Krejcy, K., Grohmann-Izay, B., Hasselbalch, H. C., Kralovics, R., Kiladjian, J. J., Bauer, F., Berbec, N. & 41 others, Besses Raebel, C., Borbenyi, Z., Bumbea, H., Buxhofer-Ausch, V., Calbecka, M., Cayssials-Caylus, E., Cazzola, M., Cerna, O., Cucuianu, A., Dima, D. M., Forjan, E., Gheorghita, E., Greil, R., Hatalova, A., Hrubisko, M., Jakucs, J., Kaplan, P., Klymenko, S., Koschmieder, S., Lazaroiu, M., Lysa, T., Masliak, Z., Masszi, T., Mihaylov, G., Myasnikov, A., Platzbecker, U., Puyade, M., Rey, J., Roy, L., Schwarz, J., Skotnicki, A., Sokolova, I., Soroka-Wojtaszko, M., Starzak-Gwozdz, J., Stoeva, V., Torregrosa-Diaz, J. M., Vallova, A., Volodicheva, E., Warzocha, K., Willenbacher, E. & Wolf, D., 2020, In: The Lancet Haematology. 7, 3, p. e196-e208 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Safety and efficacy of the combination of sonidegib and ruxolitinib in myelofibrosis: A phase 1b/2 dose-finding study

    Gupta, V., Wolleschak, D., Hasselbalch, Hans Carl, Vannucchi, A. M., Koschmieder, S., Cervantes, F., Li, Y., Dong, T., Wroclawska, M., Bharathy, S. & Harrison, C., 2020, In: Blood advances. 4, 13, p. 3063-3071 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Tocilizumab and soluble interleukin-6 receptor in JAK2V617F somatic mutation and myeloproliferative neoplasm

    Pedersen, K. M., Çolak, Y., Hasselbalch, Hans Carl, Bojesen, Stig Egil & Nordestgaard, Børge, 2020, In: EClinicalMedicine. 22, 100337.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  60. Published

    Two-fold risk of pneumonia and respiratory mortality in individuals with myeloproliferative neoplasm: A population-based cohort study

    Pedersen, K. M., Çolak, Y., Hasselbalch, Hans Carl, Ellervik, Christina, Nordestgaard, Børge & Bojesen, Stig Egil, 2020, In: EClinicalMedicine. 21, 100295.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. 2019
  62. Published

    Ruxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis

    Bjørn, M. E., Brimnes, M. K., Gudbrandsdottir, S., Andersen, C. L., Poulsen, Henrik Enghusen, Henriksen, T., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, Oct 2019, In: Leukemia and Lymphoma. 60, 10, p. 2549-2557 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Anxiety and depression in patients with Philadelphia-negative myeloproliferative neoplasms: a nationwide population-based survey in Denmark

    Brochmann, N., Flachs, E. M., Christensen, A. I., Bak, M., Andersen, Christen Bertel L, Juel, K., Hasselbalch, Hans Carl, Zwisler, A. & Rottmann, N., 2019, In: Clinical Epidemiology. 11, p. 23-33

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Association of the blood eosinophil count with end-organ symptoms

    Bjerrum, O. W., Siersma, Volkert Dirk, Hasselbalch, Hans Carl, Lind, B. & Andersen, Christen Bertel L, 2019, In: Annals of Medicine and Surgery. 45, p. 11-18

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Bridging blood cancers and inflammation: The reduced Cancitis model

    Ottesen, J. T., Pedersen, R. K., Sajid, Z., Gudmand-hoeyer, J., Bangsgaard, K. O., Skov, V., Kjær, L., Knudsen, T. A., Pallisgaard, N., Hasselbalch, Hans Carl & Andersen, M., 2019, In: Journal of Theoretical Biology. 465, p. 90-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Cancer immune therapy for myeloid malignancies: present and future

    Holmström, M. O. & Hasselbalch, Hans Carl, 2019, In: Seminars in Immunopathology. 41, 1, p. 97-109

    Research output: Contribution to journal › Review › Research › peer-review

  67. Published

    Cancerimmunterapi til behandling af hæmatologisk cancer

    Holmström, M. O., Klausen, U., Jørgensen, N. G., Holmberg, S., Grauslund, J., Met, Ö., Svane, Inge Marie, Pedersen, Lars Møller, Knudsen, L. M., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: Ugeskrift for Laeger. 181, 10, 5 p., V06180421.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Cardiovascular disease in chronic myelomonocytic leukemia: do monocytosis and chronic inflammation predispose to accelerated atherosclerosis?

    Elbæk, M. V., Sørensen, A. L. & Hasselbalch, Hans Carl, 2019, In: Annals of Hematology. 98, 1, p. 101-109

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Effect of thrombopoietin receptor agonists on markers of coagulation and P-selectin in patients with immune thrombocytopenia

    Garabet, L., Ghanima, W., Monceyron Jonassen, C., Skov, V., Holst, R., Mowinckel, M., Hasselbalch, Hans Carl, A. Kruse, T., Thomassen, M., Liebman, H., Bussel, J. B. & Sandset, P. M., 2019, In: Platelets. 30, 2, p. 206-212

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group

    Birgegard, G., Samuelsson, J., Ahlstrand, E., Ejerblad, E., Enevold, C., Ghanima, W., Hasselbalch, Hans Carl, Nielsen, Claus Henrik, Knutsen, H., Pedersen, Ole Birger Vesterager, Sørensen, A. & Andreasson, B., 2019, In: European Journal of Haematology. 102, 3, p. 235-240

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation

    Czech, J., Cordua, S., Weinbergerova, B., Baumeister, J., Crepcia, A., Han, L., Maié, T., Costa, I. G., Denecke, B., Maurer, A., Schubert, C., Feldberg, K., Gezer, D., Brümmendorf, T. H., Müller-newen, G., Mayer, J., Racil, Z., Kubesova, B., Knudsen, T., Sørensen, A. L. & 7 others, Holmström, M., Kjær, L., Skov, V., Larsen, T. S., Hasselbalch, Hans Carl, Chatain, N. & Koschmieder, S., 2019, In: Leukemia. 33, 4, p. 995-1010

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Methylation age as a correlate for allele burden, disease status, and clinical response in myeloproliferative neoplasm patients treated with vorinostat

    McPherson, S., Greenfield, G., Andersen, Christen Bertel L, Grinfeld, J., Hasselbalch, Hans Carl, Nangalia, J., Mills, K. I. & McMullin, M. F., 2019, In: Experimental Hematology. 79, p. 26-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Neo-antigen specific memory T-cell responses in healthy individuals

    Holmström, M. O., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: OncoImmunology. 8, 7, 2 p., 1599640.

    Research output: Contribution to journal › Letter › Research › peer-review

  74. Published

    Perspectives on interferon-alpha in the treatment of polycythemia vera and related myeloproliferative neoplasms: minimal residual disease and cure?

    Hasselbalch, Hans Carl & Holmström, M. O., 2019, In: Seminars in Immunopathology. 41, 1, p. 5-19

    Research output: Contribution to journal › Review › Research › peer-review

  75. Published

    Prevalence and phenotypes of JAK2 V617F and calreticulin mutations in a Danish general population

    Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Hasselbalch, Hans Carl & Ellervik, Christina, 2019, In: Blood. 134, 5, p. 469-479

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Progression of JAK2-mutant polycythemia vera to CALR-mutant myelofibrosis severely impacts on disease phenotype and response to therapy

    Holmström, M. O., Novotny, G. W., Petersen, J., Aaboe-Jørgensen, M., Hasselbalch, Hans Carl, Andersen, Mads Hald, Nielsen, S. L., Fassi, Daniel El & Schöllkopf, C., 2019, In: Leukemia and Lymphoma. 60, 13, p. 3296-3299

    Research output: Contribution to journal › Letter › Research › peer-review

  77. Published

    Smoking and Increased White and Red Blood Cells

    Pedersen, K. M., Çolak, Y., Ellervik, Christina, Hasselbalch, Hans Carl, Bojesen, Stig Egil & Nordestgaard, Børge, 2019, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 5, p. 965-977 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Statin treatment, oxidative stress and inflammation in a Danish population

    Sørensen, A. L., Hasselbalch, Hans Carl, Nielsen, C. H., Poulsen, Henrik Enghusen & Ellervik, C., 2019, In: Redox Biology. 21, 7 p., 101088.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Terapeutisk cancervaccination mod hæmatologisk cancer

    Holmström, M. O., Grauslund, J. H., Dahlager-Jørgensen, N. G., Klausen, U., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: Ugeskrift for Laeger. 181, 20A, 5 p., V04190233.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Time for revival of the red blood cell count and red cell mass in the differential diagnosis between essential thrombocythemia and polycythemia vera?

    Hasselbalch, Hans Carl, 2019, In: Haematologica. 104, 11, p. 2119-2125

    Research output: Contribution to journal › Editorial › Research

  81. Published

    Variant‐specific discrepancy when quantitating BCR‐ABL1 e13a2 and e14a2 transcripts using the Europe Against Cancer qPCR assay

    Kjaer, L., Skov, V., Andersen, M. T., Aggerholm, A., Clair, P., Gniot, M., Søby, K., Udby, L., Dorff, Mikkel Helleberg, Hasselbalch, Hans Carl & Pallisgaard, N., 2019, In: European Journal of Haematology. 103, 1, p. 26-34

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Vascular diseases in patients with chronic myeloproliferative neoplasms: Impact of comorbidity

    Frederiksen, H., Szépligeti, S., Bak, M., Ghanima, W., Hasselbalch, Hans Carl & Christiansen, C. F., 2019, In: Clinical Epidemiology. 2019, 11, p. 955-967

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. 2018
  84. Published

    Safety and efficacy of combination therapy of interferon-α2 and ruxolitinib in polycythemia vera and myelofibrosis

    Mikkelsen, Stine Ulrik, Kjaer, L., Bjørn, M. E., Knudsen, T. A., Sørensen, A. L., Andersen, Christen Bertel L, Bjerrum, O. W., Brochmann, N., Fassi, Daniel El , Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, Claus Henrik, Pallisgaard, N., Thomassen, M., Skov, V. & Hasselbalch, Hans Carl, Aug 2018, In: Cancer Medicine. 7, 8, p. 3571-3581 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes

    Kjaer, L., Holmström, M. O., Cordua, S., Andersen, Mads Hald, Svane, Inge Marie, Thomassen, M., Kruse, T. A., Pallisgaard, N., Skov, V. & Hasselbalch, Hans Carl, Apr 2018, In: Leukemia and Lymphoma. 59, 4, p. 973-977 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy

    Holmstrom, M. O., Martinenaite, E., Ahmad, S. M., Met, Özcan, Friese, C., Kjaer, L., Riley, C. H., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 1 Feb 2018, In: Leukemia. 32, 2, p. 429-437

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Associations between Fatigue, Physical Activity, and QoL in Patients with Myeloproliferative Neoplasms

    Tolstrup Larsen, R., Tang, L. H., Brochmann, N., Meulengracht Flachs, E., Illemann Christensen, A., Hasselbalch, Hans Carl & Zwisler, A., 2018, In: European Journal of Haematology. 100, 6, p. 550-559 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Classification and Personalized Prognosis in Myeloproliferative Neoplasms

    Grinfeld, J., Nangalia, J., Baxter, E. J., Wedge, D. C., Angelopoulos, N., Cantrill, R., Godfrey, A. L., Papaemmanuil, E., Gundem, G., MacLean, C., Cook, J., O'Neil, L., O'Meara, S., Teague, J. W., Butler, A. P., Massie, C. E., Williams, N., Nice, F. L., Andersen, C. L., Hasselbalch, H. C. & 7 others, Guglielmelli, P., McMullin, M. F., Vannucchi, A. M., Harrison, C. N., Gerstung, M., Green, A. R. & Campbell, P. J., 2018, In: The New England Journal of Medicine. 379, 15, p. 1416-1430

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Distinguishing myelofibrosis from polycythemia vera and essential thrombocythemia: The utility of enumerating circulating stem cells with aberrant hMICL expression by flow cytometry

    Herborg, L. L., Nederby, L., Hasselbalch, Hans Carl, Aggerholm, A. & Roug, A. S., 2018, In: International Journal of Laboratory Hematology. 40, 3, p. 320-325

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Effects of rituximab and dexamethasone on regulatory and proinflammatory B-cell subsets in patients with primary immune thrombocytopenia

    Gudbrandsdottir, S., Brimnes, M., Køllgaard, T., Hasselbalch, Hans Carl & Nielsen, C. H., 2018, In: European Journal of Haematology. 100, 1, p. 45-52

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Myeloproliferative Neoplasms in Danish Twins

    Andersen, M. A., Bjerrum, O. W., Ranjan, A., Skov, V., Kruse, T. A., Thomassen, M., Skytthe, A., Hasselbalch, Hans Carl & Christensen, K., 2018, In: Acta Haematologica. 139, 3, p. 195-198 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Philadelphia chromosome-negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet

    Barbui, T., Tefferi, A., Vannucchi, A. M., Passamonti, F., Silver, R. T., Hoffman, R., Verstovsek, S., Mesa, R., Kiladjian, J-J., Hehlmann, R., Reiter, A., Cervantes, F., Harrison, C., Mc Mullin, M. F., Hasselbalch, H. C., Koschmieder, S., Marchetti, M., Bacigalupo, A., Finazzi, G., Kroeger, N. & 3 others, Griesshammer, M., Birgegard, G. & Barosi, G., 2018, In: Leukemia. 32, 5, p. 1057-1069

    Research output: Contribution to journal › Review › Research › peer-review

  93. Published

    Smoking is associated with increased risk of myeloproliferative neoplasms: A general population-based cohort study

    Pedersen, K. M., Bak, M., Sørensen, A. L., Zwisler, A., Ellervik, Christina, Larsen, M. K., Hasselbalch, Hans Carl & Tolstrup, J. S., 2018, In: Cancer Medicine. 7, 11, p. 5796-5802 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Spontaneous T-cell responses against Arginase-1 in the chronic myeloproliferative neoplasms relative to disease stage and type of driver mutation

    Jørgensen, M. A., Holmström, M. O., Martinenaite, E., Riley, C. H., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 9, 8 p., e1468957.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Spontaneous T-cell responses against the immune check point programmed-death-ligand 1 (PD-L1) in patients with chronic myeloproliferative neoplasms correlate with disease stage and clinical response

    Holmström, M. O., Riley, C. H., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 6, e1433521.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    The effectiveness of exercise-based rehabilitation to patients with myeloproliferative neoplasms: An explorative study

    Pedersen, K. M., Zangger, G., Brochmann, N., Grønfeldt, B. M., Zwisler, A. D., Hasselbalch, Hans Carl & Tang, L. H., 2018, In: European Journal of Cancer Care. 27, 5, 10 p., e12865.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Whole Blood Gene Expression Profiling in patients undergoing colon cancer surgery identifies differential expression of genes involved in immune surveillance, inflammation and carcinogenesis

    Watt, S. K., Hasselbalch, Hans Carl, Skov, V., Kjær, L., Thomassen, M., Kruse, T. A., Burton, M. & Gögenur, Ismail, 2018, In: Surgical Oncology. 27, 2, p. 208-215 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. 2017
  99. Published

    Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period

    Hansen, Jakob Werner, Sandholdt, H., Siersma, Volkert Dirk, mxz703, mxz703, Holmberg, S., Bjerrum, O. W., Hasselbalch, Hans Carl, Olivarius, Niels de Fine, Grønbæk, Kirsten & Andersen, Christen Bertel L, Jul 2017, In: American Journal of Hematology. 92, 7, p. E130-E132 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  100. Published

    Non-invasive imaging of retinal blood flow in myeloproliferative neoplasms

    Willerslev, A., Hansen, M. M., Klefter, O. N., Bjerrum, O. W., Hasselbalch, Hans Carl, Clemmensen, S. N., Larsen, Michael & Munch, I. C., Mar 2017, In: Acta Ophthalmologica. 95, 2, p. 146–152

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents

    Brochmann, N., Flachs, E. M., Christensen, A. I., Andersen, Christen Bertel L, Juel, K., Hasselbalch, Hans Carl & Zwisler, A., 2017, In: Clinical Epidemiology. 9, p. 141-150

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    A retrospective analysis of the impact of treatments and blood counts on survival and the risk of vascular events during the course of polycythaemia vera

    Enblom-Larsson, A., Girodon, F., Bak, M., Hersby, D., Jooste, V., Hasselbalch, Hans Carl, Johansson, P. & Andreasson, B., 2017, In: British Journal of Haematology. 177, 5, p. 800-805

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Age-Related Macular Degeneration in Patients With Chronic Myeloproliferative Neoplasms

    Bak, M., Sørensen, Torben Lykke, Flachs, E. M., Zwisler, A., Juel, K., Frederiksen, H. & Hasselbalch, Hans Carl, 2017, In: JAMA Ophthalmology. 135, 8, p. 835-843

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

    Myrtue Nielsen, H., Andersen, Christen Bertel L, Westman, M., Sommer Kristensen, L., Asmar, F., Arvid Kruse, T., Thomassen, M., Stauffer Larsen, T., Skov, V., Lotte Hansen, L., Weis Bjerrum, O., Hasselbalch, Hans Carl, Punj, V. & Grønbæk, Kirsten, 2017, In: Scientific Reports. 7, 11 p., 6774.

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development

    Andersen, M., Sajid, Z., Pedersen, R. K., Gudmand-hoeyer, J., Ellervik, C., Skov, V., Kjær, L., Pallisgaard, N., Kruse, T. A., Thomassen, M., Troelsen, J., Hasselbalch, Hans Carl & Ottesen, J. T., 2017, In: PLOS ONE. 12, 8, 18 p., e0183620.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    Minimal residual disease or cure in MPNs? Rationales and perspectives on combination therapy with interferon-alpha2 and ruxolitinib

    Bjørn, M. E. & Hasselbalch, Hans Carl, 2017, In: Expert Review of Hematology. 10, 5, p. 393-404

    Research output: Contribution to journal › Review › Research › peer-review

  107. Published

    Molecular profiling as a novel tool to predict response to interferon-α2 in MPNs: The proof of concept in early myelofibrosis

    Hasselbalch, Hans Carl, 2017, In: Cancer. 123, 14, p. 2600-2603

    Research output: Contribution to journal › Editorial › Research

  108. Published

    Second malignancies in hydroxyurea and interferon-treated Philadelphia-negative myeloproliferative neoplasms

    Hansen, I. O., Sørensen, A. L. & Hasselbalch, Hans Carl, 2017, In: European Journal of Haematology. 98, 1, p. 75-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    The JAK2V617F and CALR exon 9 mutations are shared immunogenic neoantigens in hematological malignancy

    Holmstrom, M. O., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2017, In: OncoImmunology. 6, 11, 3 p., e1358334.

    Research output: Contribution to journal › Journal article › Research › peer-review

  110. Published

    The JAK2V617F mutation is a target for specific T cells in the JAK2V617F-positive myeloproliferative neoplasms

    Holmström, M. O., Hjortso, M. D., Ahmad, S. M., Met, Özcan, Martinenaite, E., Riley, C., Straten, P., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2017, In: Leukemia. 31, p. 495-498

    Research output: Contribution to journal › Letter › Research › peer-review

  111. 2016
  112. Published

    Chronic inflammation and autoimmunity as risk factors for the development of chronic myelomonocytic leukemia?

    Elbæk, M. V., Sørensen, A. L. & Hasselbalch, Hans Carl, 2 Aug 2016, In: Leukemia and Lymphoma. 57, 8, p. 1793-1799 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  113. Published

    Antecedent cardiovascular disease and autoimmunity in Philadelphia-negative chronic myeloproliferative neoplasms

    Sørensen, A. L. & Hasselbalch, Hans Carl, 1 Feb 2016, In: Leukemia Research. 41, p. 27-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  114. Published

    A new internet-based tool for reporting and analysing patient-reported outcomes and the feasibility of repeated data collection from patients with myeloproliferative neoplasms

    Brochmann, N., Zwisler, A., Kjerholt, M., Flachs, E. M., Hasselbalch, Hans Carl & Andersen, Christen Bertel L, 2016, In: Quality of Life Research. 25, 4, p. 835-846 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  115. Published

    Interferon-α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK2V617F-positive essential thrombocythemia and polycythemia vera

    Riley, C. H., Brimnes, M. K., Hansen, M., Jensen, M. K., Hasselbalch, Hans Carl, Kjaer, L., Straten, P. T. & Svane, Inge Marie, 2016, In: European Journal of Haematology. 97, 1, p. 83-92 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  116. Published

    Optimal therapy for polycythemia vera and essential thrombocythemia: Preferred use of interferon therapy based on phase 2 trials

    Silver, R. T. & Hasselbalch, Hans Carl, 2016, In: Hematology. 21, 7, p. 387-391 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  117. 2015
  118. Published

    WHO classification 2008 of myeloproliferative neoplasms: a workshop learning effect - the Danish experience

    Madelung, A. B., Bondo, H., Stamp, I., Løvgreen, P., Nielsen, S. L., Falensteen, A., Knudsen, H., Svendsen, K. D., Lange, Theis, Ralfkiaer, E., Nielsen, K., Hasselbalch, Hans Carl & Thiele, J., Sep 2015, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 123, 9, p. 787-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  119. Published

    Association of the blood eosinophil count with hematological malignancies and mortality

    Andersen, Christen Bertel L, Siersma, Volkert Dirk, Hasselbalch, Hans Carl, Vestergaard, H., Mesa, R., Felding, P., Olivarius, Niels de Fine & Bjerrum, O. W., Mar 2015, In: American Journal of Hematology. 90, 3, p. 225-229 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  120. Published

    Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

    Andersen, Christen Bertel L, Nielsen, H. M., Sommer Kristensen, L., Helbo, A. S., Vikeså, J., Jønson, L., Nielsen, Finn Cilius, Hasselbalch, Hans Carl, Bjerrum, O. W., Punj, V. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 38, p. 40588-97 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  121. 2014
  122. Published

    Circulating YKL-40 in myelofibrosis a potential novel biomarker of disease activity and the inflammatory state

    Bjørn, M. E., Andersen, Christen Bertel L, Jensen, M. K. & Hasselbalch, Hans Carl, 2014, In: European Journal of Haematology. 93, 3, p. 224-228 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  123. 2013
  124. Published

    The role of cytokines in the initiation and progression of myelofibrosis

    Hasselbalch, Hans Carl, Apr 2013, In: Cytokine & Growth Factor Reviews. 24, 2, p. 133-45 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  125. Published

    Chronic inflammation as a promotor of mutagenesis in essential thrombocythemia, polycythemia vera and myelofibrosis. A human inflammation model for cancer development?

    Hasselbalch, Hans Carl, Feb 2013, In: Leukemia Research. 37, 2, p. 214-20 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  126. Published

    Interferon and the treatment of polycythemia vera, essential thrombocythemia and myelofibrosis

    Silver, R. T., Kiladjian, J. & Hasselbalch, Hans Carl, Feb 2013, In: Expert Review of Hematology. 6, 1, p. 49-58 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  127. 2012
  128. Published

    Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: Identification of deregulated genes of significance for inflammation and immune surveillance

    Skov, V., Thomassen, M., Kruse, T. A., Larsen, T. S., Riley, C. H., Jensen, M. S. K., Bjerrum, O. W. & Hasselbalch, Hans Carl, 1 Nov 2012, In: Leukemia Research. 36, 11, p. 1387-1392 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  129. Published

    Gene expression profiling with principal component analysis depicts the biological continuum from essential thrombocythemia over polycythemia vera to myelofibrosis

    Skov, V., Thomassen, M., Kruse, T. A., Riley, C. H., Jensen, M. K., Bjerrum, O. W., Hasselbalch, Hans Carl & Larsen, T. S., 1 Sep 2012, In: Experimental Hematology. 40, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  130. Published

    Thrombopoietin-receptor agonists in haematological disorders: The Danish experience

    Gudbrandsdottir, S., Hasselbalch, Hans Carl & Frederiksen, H., 1 Sep 2012, In: Platelets. 23, 6, p. 423-429 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  131. Published

    Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer?

    Hasselbalch, Hans Carl, 5 Apr 2012, In: Blood. 119, 14, p. 3219-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  132. Published

    Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms

    Andersen, Christen Bertel L, Grønbæk, Kirsten & Hasselbalch, Hans Carl, 1 Apr 2012, In: Leukemia Research. 36, 4, p. 485-487 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  133. Published

    A highly sensitive quantitative real-time pcr assay for determination of mutant jak2 exon 12 allele burden

    Kjær, L., Riley, C. H., Westman, M., Høgdall, Estrid Vilma Solyom, Bjerrum, O. W. & Hasselbalch, Hans Carl, 5 Mar 2012, In: PLOS ONE. 7, 3

    Research output: Contribution to journal › Journal article › Research › peer-review

  134. Published

    A novel immunohistochemical sequential multi-labelling and erasing technique enables epitope characterization of bone marrow pericytes in primary myelofibrosis

    Madelung, A., Bzorek, M., Bondo, H., Zetterberg, E., Bjerrum, O. W., Hasselbalch, Hans Carl, Scheding, S. & Ralfkiaer, E., 2012, In: Histopathology. 60: 554 – 660.

    Research output: Contribution to journal › Journal article › Research › peer-review

  135. Published

    Somatic mutations of the CREBBP and EP300 genes affect response to histone deacetylase inhibition in malignant DLBCL clones

    Andersen, Christen Bertel L, Asmar, F., Klausen, T., Hasselbalch, Hans Carl & Grønbæk, K., 2012, In: Leukemia Research Reports. 2, 1, p. 1-3 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  136. 2011
  137. Published

    Chronic myeloproliferative neoplasms and subsequent cancer risk: A Danish population-based cohort study

    Frederiksen, H., Farkas, D. K., Christiansen, C. F., Sørensen, H. T. & Hasselbalch, Hans Carl, 15 Dec 2011, In: Blood. 118, 25, p. 6515-6520 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  138. Published

    A new era for IFN-α in the treatment of Philadelphia-negative chronic myeloproliferative neoplasms

    Hasselbalch, Hans Carl, 1 Dec 2011, In: Expert Review of Hematology. 4, 6, p. 637-655 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  139. Published

    Fibroproliferative activity in patients with immune thrombocytopenia (ITP) treated with thrombopoietic agents

    Ghanima, W., Bussel, J. B., Junker, P., Hasselbalch, Hans Carl, Gudbrandsdottir, S., Boiocchi, L., Geyer, J. T., Orazi, A. & Feng, X., 1 Oct 2011, In: British Journal of Haematology. 155, 2, p. 248-255 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  140. Published

    Increase in circulating CD4CD25Foxp3 T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α

    Riley, C. H., Morten Krogh, J., Brimnes, M. K., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Bjerrum, O. W., 25 Aug 2011, In: Blood. 118, 8, p. 2170-2173 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  141. Published

    Interferon alfa in the treatment of philadelphia-negative chronic myeloproliferative neoplasms

    Hasselbalch, Hans Carl, Kiladjian, J. & Silver, R. T., 20 Jun 2011, In: Journal of Clinical Oncology. 29, 18

    Research output: Contribution to journal › Journal article › Research › peer-review

  142. Published

    Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European leukemiaNet

    Barbui, T., Barosi, G., Birgegard, G., Cervantes, F., Finazzi, G., Griesshammer, M., Harrison, C., Hasselbalch, H. C., Hehlmann, R., Hoffman, R., Kiladjian, J-J., Kröger, N., Mesa, R., McMullin, M. F., Pardanani, A., Passamonti, F., Vannucchi, A. M., Reiter, A., Silver, R. T., Verstovsek, S. & 1 others, Tefferi, A., 20 Feb 2011, In: Journal of Clinical Oncology. 29, 6, p. 761-770 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  143. Published

    Interferon alpha2 in the treatment of hematological malignancies. status and perspectives

    Hasselbalch, Hans Carl, 1 Jan 2011, In: Current Drug Targets. 12, 3, p. 387-391 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  144. Published

    Interferon-alpha in the treatment of Philadelphia-negative chronic myeloproliferative neoplasms. Status and perspectives

    Hasselbalch, Hans Carl, Larsen, T. S., Riley, C. H., Jensen, M. K. & Kiladjian, J., 1 Jan 2011, In: Current Drug Targets. 12, 3, p. 392-419 28 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  145. Published

    High expression of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 6 and 8 in primary myelofibrosis

    Hasselbalch, Hans Carl, Skov, V., Larsen, T. S., Thomassen, M., Riley, C. H., Jensen, M. K., Bjerrum, O. W. & Kruse, T. A., 2011, In: Leukemia Research. 35, 10, p. 1330-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  146. 2008
  147. Published

    Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence

    Lataillade, J. J., Pierre-Louis, O., Uzan, G., Jasmin, C., Martyre, M. C., Bousse-Kerdiles, M. C. L. & Hasselbalch, Hans Carl, 2008, In: Blood. 112, 8, p. 3026-3035 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  148. 1996
  149. Published

    Sonographic measurement of the thymus in infants

    Hasselbalch, Hans Carl, Nielsen, Michael Bachmann, Jeppesen, Dorthe Lisbeth, Pedersen, J. F. & Karkov, J., 1996, In: European Radiology. 6, 5, p. 700-703 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 2849472